Prognostic impact of comorbidity in elderly lung cancer patients: Use and comparison of two scores

Lung Cancer

Volumn 72, Issue 1, 2011, Pages 108-113

  Gironés, Regina ^a   Torregrosa, Dolores ^a   Gómez Codina, José ^b   Maestu, Inma ^c   Tenias, Jose M ^d   Rosell, Rafael ^e  

^a HOSPITAL LLUÍS ALCANYÍS   (Spain)

^b HOSPITAL UNIVERSITARIO LA FE   (Spain)

^c HOSPITAL UNIVERSITARIO DR PESET   (Spain)

^d Investigation Unit from La Mancha Centro Hospital   (Spain)

^e HOSPITAL UNIVERSITARI GERMANS TRIAS I PUJOL   (Spain)

Author keywords

Age; Charlson; Comorbidity; Elderly; Lung cancer; SCS

Indexed keywords

AGED; ARTICLE; CANCER GROWTH; CANCER STAGING; CANCER SURVIVAL; CARDIOVASCULAR DISEASE; CAUSE OF DEATH; CHRONIC OBSTRUCTIVE LUNG DISEASE; CIGARETTE SMOKING; COMORBIDITY; FEMALE; HUMAN; LUNG CANCER; MAJOR CLINICAL STUDY; MALE; PREVALENCE; PRIORITY JOURNAL; PROGNOSIS; SCORING SYSTEM;

AGED; AGED, 80 AND OVER; CAUSE OF DEATH; COMORBIDITY; FEMALE; HUMANS; LUNG NEOPLASMS; MALE; PREVALENCE; PROGNOSIS; PROSPECTIVE STUDIES; SURVIVAL ANALYSIS;

EID: 79952185210     PISSN: 01695002     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lungcan.2010.07.001     Document Type: Article

References (24)

1. Birim O., Kappetein A.P., Bogers J.J.C. Charlson comorbidity index as a predictor of long-term outcome after surgery for non-small cell lung cancer. Eur J Cardio-thoracic Surg 2005, 28:759-762.
2. Janssen-Heijnen M.L., Smulders S., Lemmens V.E., Smeenk F.W., van Geffen H.J., Coebergh J.W. Effect of comorbidity on the treatment and prognosis of elderly patients with non-small cell lung cancer. Thorax 2004, 59:602-607.
3. Charlson M., Szatrowski T.P., Peterson, Gold J. Validation of a combined comorbidity index. J Clin Epidemiol 1994, 47:1245-1251.
4. Colinet B., Jacot W., Bertrand D., Lacombe S., Bozonnat M.-C., Daurès J.-P., et al. A new simplified comorbidity score as a prognostic factor in non-small-cell lung cancer patients: description and comparison with the Charlson's index. Br J Cancer 2005, 93:1098-1105.
5. Extermann M., Overcash J., Lyman G.H., Parr J., Balducci L. Comorbidity and functional status are independent in older cancer patients. J Clin Oncol 1998, 16:1582-1587.
6. Domingo E., Suriñach J.M., Murillo J., Duran M., Suriñach J., Baselga J., et al. Prognostic factors in the diagnostic work-up of cancer patients in an internal medicine department: does age matter? Int J Clin Pract 2008, 62(11):1723-1729.
7. Jacot W., Colinet B., Bertrand D., Lacombe S., Bozonnat M.-C., Daurès J.-P., et al. Quality of life and comorbidity score as prognostic determinants in non-small-cell lung cancer patients. Ann Oncol 2008, 19:1458-1464.
8. Hervé LeCaer, Barlesi F., Robinet G., Fournel P., Geriniere L., Bombaron P., et al. An open multicenter phase II trial of weekly docetaxel for advanced-stage non-small-cell lung cancer in elderly patients with significant comorbidity and/or poor performance status: the GFPC 02-02b study. Lung Cancer 2007, 57:72-78.
9. Zubrod C.G. Origins and development of chemotherapy research at the National Cancer Institute. Cancer Treat Rep 1984, 68(1):9-19.
10. Balducci L., Extermann M. Management of cancer in the older person: a practical approach. Oncologist 2000, 5:224-237.
11. Rao A.V., Pearl H.S., Cohen H.J. Geriatric assessment and comorbidity. Semin Oncol 2004, 31(2):149-159.
12. Aapro M., kohne C.H., Cohen H.J., Extermann M. Never too old? Age should be a barrier to enrollment in cancer clinical trials. Oncologist 2005, 10:198-204.
13. Extermann M., Aapro M., Bernabei R., Cohen H.J., Droz J.P., Lichtman S., et al. Use of comprehensive geriatric assessment in older cancer patients: recommendations from the task force on CGA of the International Society of Geriatric Oncology (SIOG). Crit Rev Oncol Hematol 2005, 55(3):241-252.
14. Maestu I., Muñoz J., Gómez-Aldaravi L., Esquerdo G., Yubero A., Torregrosa M.D., et al. Assessment of functional status, symptoms and comorbidity in elderly patients with advanced non-small-cell lung cancer (NSCLC) treated with gemcitabine and vinorelbine. Clin Transl Oncol 2007, 9:99-105.
15. Ambrogi V., Pompeo E., Elia E., Pistolese G.R., Mineo T.C. The impact of cardiovascular comorbidity on the outcome of surgery for stages I and II non-small-cell lung cancer. Eur J Cardio-Thorac Surg 2003, 23:811-817.
16. Ludbrook J.J.S., Truong P.T., MacNeil M.V., Lesperance M., Webber A., Joe H., et al. Do age and comorbidity impact treatment allocation and outcomes in limited stage small-cell lung cancer? A community-based population analysis. Int J Radiat Oncol Biol Phys 2003, 55:1321-1330.
17. Firat S., Bousamra M., Gore E., Byhardt R.W. Comorbidity and KPS are independent prognostic factors in stage I non-small-cell lung cancer. Int J Radiat Oncol Biol Phys 2002, 52:1047-1057.
18. Firat S., Pleister A., Byhardt R.W., Gore E. Age is independent of comorbidity influencing patient selection for combined modality therapy for treatment of stage III non-small cell lung cancer (NSCLC). Am J Clin Oncol 2006, 29:252-257.
19. Battafarano R.J., Piccirillo J.F., Meyers B.F., Hsu H.S., Guthrie T.J., Cooper J.D., et al. Impact of comorbidity on survival after surgical resection in patients with stage I non-small cell lung cancer. J Thorac Cardiovasc Surg 2002, 123:280-287.
20. Tammemagi C.M., Neslund-Dudas C., Simoff M., Kvale P. Impact of comorbidity on lung cancer survival. Int J Cancer 2003, 103:792-802.
21. Asmis T.R., Ding K., Seymour L., Shepherd F.A., Leighl N.B., Witehead M., et al. Age and comorbidity as independent prognostic factors in the treatment of non-small-cell lung cancer: a review of National Cancer Institute of Canada Clinical Trials Group Trials. J Clin Oncol 2008, 26:54-59.
22. Miyazaki K., Kikuchi N., Satoh H., Sekizawa K., Janssen-Heijnen M.L.G., Coebergh J.W.W. Comorbidity in elderly NSCLC patients. Thorax 2005, 60:704.
23. Piccirillo J.F., Tierney R.M., Costas I., Grove L., Spitznagel E.L. Prognostic importance of comorbidity in a hospital-based cancer registry. JAMA 2004, 291:2441-2447.
24. Read W.L., Tierney R.M., Page N.C., Costas I., Govidan R., Spitznagel E.L.J., et al. Differential prognostic impact of comorbidity. J Clin Oncol 2004, 22:3099-3103.