Increased oxidative stress and iron overload in Jordanian β-thalassemic children

Hemoglobin

Volumn 35, Issue 1, 2011, Pages 67-79

  Abdalla, Maher Y ^a   Fawzi, Mohammad ^a   Al Maloul, Salem R ^a   El Banna, Nasser ^a   Tayyem, Reema F ^a   Ahmad, Iman M ^a  

^a HASHEMITE UNIVERSITY   (Jordan)

Author keywords

Glutathione (GSH); Oxidative stress; Thalassemia; thiobarbituric acid reactive substances (TBARS)

Indexed keywords

ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; CATALASE; FERRITIN; GAMMA GLUTAMYLTRANSFERASE; HEMOGLOBIN; IRON; LIVER ENZYME; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE; THIOBARBITURIC ACID REACTIVE SUBSTANCE;

ANTIOXIDANT ACTIVITY; ARTICLE; BLOOD LEVEL; BLOOD TRANSFUSION; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME BLOOD LEVEL; FEMALE; FERRITIN BLOOD LEVEL; HEMOGLOBIN BLOOD LEVEL; HUMAN; IRON OVERLOAD; JORDAN; LIPID PEROXIDATION; MALE; OXIDATIVE STRESS; PRESCHOOL CHILD; SCHOOL CHILD; SEX DIFFERENCE; THALASSEMIA MAJOR;

BETA-THALASSEMIA; BLOOD TRANSFUSION; CASE-CONTROL STUDIES; CATALASE; CHILD; CHILD, PRESCHOOL; DEFEROXAMINE; ENZYME ASSAYS; FEMALE; FERRITINS; HUMANS; IRON; IRON OVERLOAD; JORDAN; LIVER; MALE; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; SUPEROXIDE DISMUTASE; THIOBARBITURIC ACID REACTIVE SUBSTANCES;

EID: 79952169044     PISSN: 03630269     EISSN: 1532432X     Source Type: Journal    
DOI: 10.3109/03630269.2010.544624     Document Type: Article

References (55)

1. Manca L, Masala B. Disorders of the synthesis of human fetal hemoglobin. IUBMB Life. 2008;60(2):94-111.
2. Clegg JB, Weatherall DJ. Thalassemia and malaria: new insights into an old problem. Proc Assoc Am Phys.1999;111(4):278-282. (Pubitemid 29331458)
3. Sutcharitchan P, Saiki R, Huisman THJ, et al. Reverse dot-blot detection of the African-American β-thalassemia mutations. Blood. 1995;86(4):1580-1585.
4. Hilliard LM, Berkow RL. The thalassemia syndromes. Primary Care Update for OB/GYNS. 1996;3(5):157-162 (http://www.sciencedirect.com/science/article/ B6TMB-3W3NBGY-2/2/b6ae9d3dcab796ef4e002acc7bab99b6).
5. Mehrvar A, Azarkeivan A, Faranoush M, et al. Endocrinopathies in patients with transfusion-dependent β-thalassemia. Pediatr Hematol Oncol. 2008;25(3):187-194.
6. Scott MD. H2O2 injury in β thalassemic erythrocytes: protective role of catalase and the prooxidant effects of GSH. Free Radic Biol Med. 2006;40(7):1264-1272.
7. Meral A, Tuncel P, Sürmen-Gür E, Ozbek R, Oztürk E. Lipid peroxidation and antioxidant status in β-thalassemia. Pediatr Hematol Oncol. 2000;17(8):687-693.
8. Advani R, Rubin E, Mohandas N, Schrier S. Oxidative red blood cell membrane injury in the pathophysiology of severe mouse β-thalassemia. Blood. 1992;79(4):1064-1067.
9. Olivieri O, De Franceschi L, Capellini MD, Girelli D, Corrocher R, Brugnara C. Oxidative damage and erythrocyte membrane transport abnormalities in thalassemias. Blood. 1994;84(1):315-320. (Pubitemid 24193836)
10. Grinberg LN, Rachmilewitz EA, Kitrossky N, Chevion M. Hydroxyl radical generation in β-thalassemic red blood cells. Free Radic Biol Med. 1995;18(3):611-615.
11. Schrier SL, Centis F, Verneris M, Ma L, Angelucci E. The role of oxidant injury in the pathophysiology of human thalassemias. Redox Rep. 2003;8(5):241-245. (Pubitemid 38035580)
12. Ohkawa H, Ohishi N, Yagi K. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem. 1979;95(2):351-358. (Pubitemid 9194347)
13. Setianingsih I, Williamson R, Marzuk S, Harahap A, Tamam M, Forrest S. Molecular basis of β-thalassemia in indonesia: application to prenatal diagnosis. Molec Diagn. 1998;3(1):11-20. (Pubitemid 28311193)
14. Scott MD, Eaton JW. Thalassaemic erythrocytes: cellular suicide arising from iron and glutathione-dependent oxidation reactions? Br J Haematol. 1995;91(4):811-819.
15. Chan AC, Chow CK, Chiu D. Interaction of antioxidants and their implication in genetic anemia. Proc Soc Exp Biol Med.1999;222(3):274-282. (Pubitemid 129708642)
16. Watkins JA, Kawanishi S, Caughey WS. Autoxidation reactions of Hemoglobin A free from other red cell components: a minimal mechanism. Biochem Biophys Res Commun. 1985;132(2):742-748. (Pubitemid 16198687)
17. Das SK, Nair RC. Superoxide dismutase, glutathione peroxidase, catalase and lipid peroxidation of normal and sickled erythrocytes. Br J Haematol. 1980;44(1):87-92. (Pubitemid 10201711)
18. Gaston BM. Nitric oxide and radicals in the pulmonary vasculature. Pediatr Pulmonol 1998;25(5):353-354.
19. Geetha RK, Vasudevan DM. Inhibition of lipid peroxidation by botanical extracts of Ocimum sanctum: in vivo and in vitro studies. Life Sci. 2004; 76(1):21-28. (Pubitemid 39389168)
20. Kassab-Chekir A, Laradi S, Ferchichi S, et al. Oxidant, antioxidant status and metabolic data in patients with β-thalassemia. Clin Chim Acta. 2003;338(1-2):79-86. (Pubitemid 37456693)
21. Borgna-Pignatti C, Rugolotto S, De Stefano P, et al. Survival and disease complications in thalassemia major. Ann NY Acad Sci. 1998;850:227-231. (Pubitemid 28369763)
22. Weatherall DJ, Clegg JB. Thalassemia - a global public health problem. Nat Med. 1996;2(8):847-849. (Pubitemid 26296746)
23. Halle M, König D, Berg A, Keul J, Baumstark MW. Relationship of serum ferritin concentrations with metabolic cardiovascular risk factors in men without evidence for coronary artery disease. Atherosclerosis. 1997;128(2):235-240. (Pubitemid 27092158)
24. Canale VC, Steinherz P, New M, Erlandson M. Endocrine function in thalassemia major. Ann NY Acad Sci. 1974;232:333-345.
25. Knutson MD, Walter PB, Ames BN, Viteri FE. Both iron deficiency and daily iron supplements increase lipid peroxidation in rats. J Nutr. 2000;130(3):621-628. (Pubitemid 30118081)
26. Poli G. Pathogenesis of liver fibrosis: role of oxidative stress. Molec Aspects Med. 2000;21(3):49-98. (Pubitemid 30642764)
27. Boyd JW. The intracellular distribution, latency and electrophoretic mobility of l-glutamate-oxaloacetate transaminase from rat liver. Biochem J. 1961;81(2):434-441.
28. Livrea M, Tesoriere L, Pintaudi A, et al. A. Oxidative stress and antioxidant status in β-thalassemia major: iron overload and depletion of lipid-soluble antioxidants. Blood 1996; 88(9):3608-3614.
29. Panigrahi I, Agarwal S. Thromboembolic complications in β-thalassemia: beyond the horizon. Thromb Res. 2007;120(6):783-789. (Pubitemid 47422335)
30. Muretto P, Angelucci E, Lucarelli G. Reversibility of cirrhosis in patients cured of thalassemia by bone marrow transplantation. Ann Intern Med. 2002;136(9):667-672. (Pubitemid 34462679)
31. Prati D, Maggioni M, Milani S, et al. Clinical and histological characterization of liver disease in patients with transfusion-dependent β-thalassemia. A multicenter study of 117 cases. Haematologica. 2004;89(10):1179-1186.
32. Sanyal AJ, American Gastroenterological Association. AGA technical review on nonalcoholic fatty liver disease. Gastroenterology. 2002;123(5):1705-1725. (Pubitemid 35231670)
33. De Gobbi M, Pasquero P, Brunello F, Paccotti P, Mazza U, Camaschella C. Juvenile hemochromatosis associated with β-thalassemia treated by phlebotomy and recombinant human erythropoietin. Haematologica. 2000;85(8):865-867.
34. Zhihua Z, Goldstein BD, Witz G. Iron-stimulated ring-opening of benzene in a mouse liver microsomal system: mechanistic studies and formation of a new metabolite. Biochem Pharmacol. 1995;50(10):1607-1617.
35. Ryan TP, Aust SD. The role of iron in oxygen-mediated toxicities. Crit Rev Toxicol. 1992;22(2):119-141.
36. Selek S, Aslan M, Horoz M, Gur M, Erel O. Oxidative status and serum PON1 activity in β-thalassemia minor. Clin Biochem. 2007;40(5-6):287-291.
37. Ludwiczek S, Aigner E, Theurl I,Weiss G. Cytokine-mediated regulation of iron transport in human monocytic cells. Blood. 2003;101(10):4148-4154. (Pubitemid 36857898)
38. Dirican M, Safak Ö, Uncu G, Sarandöl E. Susceptibility of red blood cell lipids to in vitro oxidation and antioxidant status in preeclampsia. Eur J Obstet Gynecol Reprod Biol. 2008;140(2):158-164.
39. Nielsen F, Mikkelsen BB, Nielsen JB, Andersen HR, Grandjean P. Plasma malondialdehyde as biomarker for oxidative stress: reference interval and effects of life-style factors. Clin Chem. 1997;43(7):1209-1214. (Pubitemid 27297265)
40. Grotto D, Santa Maria LD, Boeira S, et al. Rapid quantification of malondialdehyde in plasma by high performance liquid chromatography-visible detection. J Pharm Biomed Anal. 2007;43(2):619-624. (Pubitemid 44960559)
41. Dorléac E, Morlé L, Gentilhomme O, Jaccoud P, Baudonnet C, Delaunay J. Thalassemia-like abnormalities of the red cell membrane in Hemoglobin E trait and disease. Am J Hematol. 1984;16(3):207-217. (Pubitemid 14127678)
42. Cighetti G, Duca L, Bortone L, et al. Oxidative status and malondialdehyde in β-thalassaemia patients. Eur J Clin Invest. 2002;32(Suppl. 1):55-60. (Pubitemid 41704989)
43. Naithani R, Chandra J, Narayan S, Sharma S, Singh V. Thalassemia major - on the verge of bleeding or thrombosis? Hematology. 2006;11(1):57-61.
44. Miller NJ, Rice-Evans C, Davies MJ, Gopinathan V, Milner A. A novel method for measuring antioxidant capacity and its application to monitoring the antioxidant status in premature neonates. Clin Sci. 1993;84(4):407-412. (Pubitemid 23113948)
45. Naithani R, Chandra J, Bhattacharjee J, Verma P, Narayan S. Peroxidative stress and antioxidant enzymes in children with β-thalassemia major. Pediatr Blood Cancer. 2006;46(7):780-785. (Pubitemid 43726427)
46. Moreno-Manzano V, Ishikawa Y, Lucio-Cazana J, Kitamura M. Selective involvement of superoxide anion, but not downstream compounds hydrogen peroxide and peroxynitrite, in tumor necrosis factor-α-induced apoptosis of rat mesangial cells. J Biol Chem. 2000;275(17):12684-12691. (Pubitemid 30241419)
47. Çimen MY. Free radical metabolism in human erythrocytes. Clin Chim Acta. 2008;390(1-2):1-11.
48. Jaffe E. Clinical profile: hereditary hemolytic disorders and enzymatic deficiencies of human erythrocytes. Blood. 1970;35(1):116-134.
49. Vetrano AM, Heck DE, Mariano TM, Mishin V, Laskin DL, Laskin JD. Characterization of the oxidase activity in mammalian catalase. J Biol Chem. 2005;280(42):35372-35381. (Pubitemid 41532726)
50. Gibbons NCJ, Wood JM, Rokos H, Schallreuter KU. Computer simulation of native epidermal enzyme structures in the presence and absence of hydrogen peroxide (H2O2): potential and pitfalls. J Invest Dermatol. 2006;126(12):2576- 2582. (Pubitemid 44764041)
51. Churbanova IY, Sevrioukova IF. Redox-dependent changes in molecular properties of mitochondrial apoptosis-inducing factor. J Biol Chem. 2008;283(9):5622-5631.
52. Walter PB, Fung EB, Killilea DW, et al. Oxidative stress and inflammation in iron-overloaded patients with β-thalassaemia or sickle cell disease. Br J Haematol. 2006;135(2):254-263. (Pubitemid 44401624)
53. Cheng ML, Ho HY, Tseng HC, Lee CH, Shih LY, Chiu DT. Antioxidant deficit and enhanced susceptibility to oxidative damage in individuals with different forms of α-thalassaemia. Br J Haematol. 2005;128(1):119-127.
54. Marín J, Rodríguez-Martínez MA. Nitric oxide, oxygen-derived free radicals and vascular endothelium. J Auton Pharmacol. 1995;15(4):279-307.
55. Cappellini MD, Tavazzi D, Duca L, et al. Metabolic indicators of oxidative stress correlate with haemichrome attachment to membrane, band 3 aggregation and erythrophagocytosis in β-thalassaemia intermedia. Br J Haematol. 1999;104(3):504-512.