-
1
-
-
14944385553
-
Global cancer statistics, 2002
-
Parkin, D.M.; Bray, F.; Ferlay, J.; Pisani, P. Global cancer statistics, 2002. CA Cancer J. Clin. 2005, 55, 74-108.
-
(2005)
CA Cancer J. Clin.
, vol.55
, pp. 74-108
-
-
Parkin, D.M.1
Bray, F.2
Ferlay, J.3
Pisani, P.4
-
2
-
-
41349099104
-
Cancer statistics, 2008
-
Jemal, A.; Siegel, R.; Ward, E.; Hao, Y.; Xu, J.; Murray, T.; Thun, M.J. Cancer statistics, 2008. CA Cancer J. Clin. 2008, 58, 71-96.
-
(2008)
CA Cancer J. Clin.
, vol.58
, pp. 71-96
-
-
Jemal, A.1
Siegel, R.2
Ward, E.3
Hao, Y.4
Xu, J.5
Murray, T.6
Thun, M.J.7
-
3
-
-
45949104460
-
New therapies for ovarian cancer: Cytotoxics and molecularly targeted agents
-
Dinh, P.; Harnett, P.; Piccart-Gebhart, M.J.; Awada, A. New therapies for ovarian cancer: cytotoxics and molecularly targeted agents. Crit. Rev. Oncol. Hematol. 2008, 67, 103-112.
-
(2008)
Crit. Rev. Oncol. Hematol.
, vol.67
, pp. 103-112
-
-
Dinh, P.1
Harnett, P.2
Piccart-Gebhart, M.J.3
Awada, A.4
-
4
-
-
0035114558
-
Cancer statistics, 2001
-
Greenlee, R.T.; Hill-Harmon, M.B.; Murray, T.; Thun, M. Cancer statistics, 2001. CA Cancer J. Clin. 2001, 51, 15-36.
-
(2001)
CA Cancer J. Clin.
, vol.51
, pp. 15-36
-
-
Greenlee, R.T.1
Hill-Harmon, M.B.2
Murray, T.3
Thun, M.4
-
5
-
-
0141688377
-
Phase III trial of carboplatin and paclitaxel compared with cisplatin and paclitaxel in patients with optimally resected stage III ovarian cancer: A Gynecologic Oncology Group study
-
Ozols, R.F.; Bundy, B.N.; Greer, B.E.; Fowler, J.M.; Clarke-Pearson, D.; Burger, R.A.; Mannel, R.S.; DeGeest, K.; Hartenbach, E.M; Baergen, R. Phase III trial of carboplatin and paclitaxel compared with cisplatin and paclitaxel in patients with optimally resected stage III ovarian cancer: a Gynecologic Oncology Group study. J. Clin. Oncol. 2003, 21, 3194-3200.
-
(2003)
J. Clin. Oncol.
, vol.21
, pp. 3194-3200
-
-
Ozols, R.F.1
Bundy, B.N.2
Greer, B.E.3
Fowler, J.M.4
Clarke-Pearson, D.5
Burger, R.A.6
Mannel, R.S.7
Degeest, K.8
Hartenbach, E.M.9
Baergen, R.10
-
6
-
-
1242275074
-
Systemic treatment policies in ovarian cancer: The next 10 years
-
Biagi, J.J.; Eisenhauer, E.A. Systemic treatment policies in ovarian cancer: the next 10 years. Int. J. Gynecol. Cancer 2003, 13(Suppl 2), 231-240.
-
(2003)
Int. J. Gynecol. Cancer
, vol.13
, Issue.SUPPL. 2
, pp. 231-240
-
-
Biagi, J.J.1
Eisenhauer, E.A.2
-
7
-
-
0037037385
-
First-line treatment for advanced ovarian cancer: Paclitaxel, platinum and the evidence
-
Sandercock, J.; Parmar, M.K.; Torri, V.; Qian, W. First-line treatment for advanced ovarian cancer: paclitaxel, platinum and the evidence. Br. J. Cancer 2002, 87, 815-824.
-
(2002)
Br. J. Cancer
, vol.87
, pp. 815-824
-
-
Sandercock, J.1
Parmar, M.K.2
Torri, V.3
Qian, W.4
-
8
-
-
19744368302
-
Cancer of the ovary
-
Cannistra, S.A. Cancer of the ovary. N. Engl. J. Med. 2004, 351, 2519-2529.
-
(2004)
N. Engl. J. Med.
, vol.351
, pp. 2519-2529
-
-
Cannistra, S.A.1
-
9
-
-
0043240182
-
Ovarian cancer: Strategies for overcoming resistance to chemotherapy
-
Agarwal, R.; Kaye, S.B. Ovarian cancer: strategies for overcoming resistance to chemotherapy. Nat. Rev. Cancer 2003, 3, 502-516.
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 502-516
-
-
Agarwal, R.1
Kaye, S.B.2
-
10
-
-
0037103424
-
Efficacy and safety of imatinib mesylate in advanced gastrointestinal stromal tumors
-
Demetri, G.D.; von Mehren, M.; Blanke, C.D.; van den Abbeele, A.D.; Eisenberg, B.; Roberts, P.J.; Heinrich, M.C.; Tuveson, D.A.; Singer, S.; Janicek, M. et al. Efficacy and safety of imatinib mesylate in advanced gastrointestinal stromal tumors. N. Engl. J. Med. 2002, 347, 472-480.
-
(2002)
N. Engl. J. Med.
, vol.347
, pp. 472-480
-
-
Demetri, G.D.1
von Mehren, M.2
Blanke, C.D.3
van den Abbeele, A.D.4
Eisenberg, B.5
Roberts, P.J.6
Heinrich, M.C.7
Tuveson, D.A.8
Singer, S.9
Janicek, M.10
-
11
-
-
2542561964
-
Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
-
Hurwitz, H.; Fehrenbacher, L.; Novotny, W.; Cartwright, T.; Hainsworth, J.; Heim, W.; Berlin, J.; Baron, A.; Griffing, S.; Holmgren, E., et al. Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. N. Engl. J. Med. 2004, 350, 2335-2342.
-
(2004)
N. Engl. J. Med.
, vol.350
, pp. 2335-2342
-
-
Hurwitz, H.1
Fehrenbacher, L.2
Novotny, W.3
Cartwright, T.4
Hainsworth, J.5
Heim, W.6
Berlin, J.7
Baron, A.8
Griffing, S.9
Holmgren, E.10
-
12
-
-
3042643346
-
Bevacizumab: An angiogenesis inhibitor with efficacy in colorectal and other malignancies
-
Zondor, S.D.; Medina, P.J. Bevacizumab: an angiogenesis inhibitor with efficacy in colorectal and other malignancies. Ann. Pharmacother. 2004, 38, 1258-1264.
-
(2004)
Ann. Pharmacother.
, vol.38
, pp. 1258-1264
-
-
Zondor, S.D.1
Medina, P.J.2
-
13
-
-
37549040613
-
Paclitaxel plus Bevacizumab versus Paclitaxel Alone for Metastatic Breast Cancer
-
Miller, K.; Wang, M.; Gralow, J.; Dickler, M.; Cobleigh, M.; Perez, E.A.; Shenkier, T.; Cella, D.; Davidson, N.E. Paclitaxel plus Bevacizumab versus Paclitaxel Alone for Metastatic Breast Cancer. N. Engl. J. Med. 2007, 357, 2666-2676.
-
(2007)
N. Engl. J. Med.
, vol.357
, pp. 2666-2676
-
-
Miller, K.1
Wang, M.2
Gralow, J.3
Dickler, M.4
Cobleigh, M.5
Perez, E.A.6
Shenkier, T.7
Cella, D.8
Davidson, N.E.9
-
14
-
-
33746911955
-
Combining Targeted Agents: Blocking the Epidermal Growth Factor and Vascular Endothelial Growth Factor Pathways
-
Sandler, A.; Herbst, R. Combining Targeted Agents: Blocking the Epidermal Growth Factor and Vascular Endothelial Growth Factor Pathways. Clin. Cancer Res. 2006, 12, 4421-4425s.
-
(2006)
Clin. Cancer Res.
, vol.12
-
-
Sandler, A.1
Herbst, R.2
-
15
-
-
34548720158
-
Sorafenib improves survival in advanced Hepatocellular Carcinoma (HCC): Result of a Phase III randomised placebo-controlled trial (SHARP trial)
-
Abstr. LBA1
-
Llovet, J.; Ricci, S.; Mazzaferro, V.; Hilgard, P.; Raoul, J.; Zeuzern, S.; Poulin-Costello, M.; Moscovici, M.; Voliotis, D.; Bruix, J. Sorafenib improves survival in advanced Hepatocellular Carcinoma (HCC): Result of a Phase III randomised placebo-controlled trial (SHARP trial). J. Clin. Oncol. 2007, 25 (18S), Abstr. LBA1.
-
(2007)
J. Clin. Oncol.
, vol.25
, Issue.18 S
-
-
Llovet, J.1
Ricci, S.2
Mazzaferro, V.3
Hilgard, P.4
Raoul, J.5
Zeuzern, S.6
Poulin-Costello, M.7
Moscovici, M.8
Voliotis, D.9
Bruix, J.10
-
16
-
-
33846148701
-
Sorafenib in advanced clear-cell renal-cell carcinoma
-
Escudier, B.; Eisen, T.; Stadler, W.M.; Szczylik, C.; Oudard, S.; Siebels, M.; Negrier, S.; Chevreau, C.; Solska, E.; Desai, A.A., et al. Sorafenib in advanced clear-cell renal-cell carcinoma. N. Engl. J. Med. 2007, 356, 125-134.
-
(2007)
N. Engl. J. Med.
, vol.356
, pp. 125-134
-
-
Escudier, B.1
Eisen, T.2
Stadler, W.M.3
Szczylik, C.4
Oudard, S.5
Siebels, M.6
Negrier, S.7
Chevreau, C.8
Solska, E.9
Desai, A.A.10
-
17
-
-
33846181370
-
Sunitinib versus interferon alfa in metastatic renalcell carcinoma
-
Motzer, R.J.; Hutson, T.E.; Tomczak, P.; Michaelson, M.D.; Bukowski, R.M.; Rixe, O.; Oudard, S.; Negrier, S.; Szczylik, C.; Kim, S.T., et al. Sunitinib versus interferon alfa in metastatic renalcell carcinoma. N. Engl. J. Med. 2007, 356, 115-124.
-
(2007)
N. Engl. J. Med.
, vol.356
, pp. 115-124
-
-
Motzer, R.J.1
Hutson, T.E.2
Tomczak, P.3
Michaelson, M.D.4
Bukowski, R.M.5
Rixe, O.6
Oudard, S.7
Negrier, S.8
Szczylik, C.9
Kim, S.T.10
-
18
-
-
34447499062
-
Novel approaches in advancing the treatment of epithelial ovarian cancer: The role of angiogenesis inhibition
-
Martin, L.; Schilder, R. Novel approaches in advancing the treatment of epithelial ovarian cancer: the role of angiogenesis inhibition. J. Clin. Oncol. 2007, 25, 2894-901.
-
(2007)
J. Clin. Oncol.
, vol.25
, pp. 2894-2901
-
-
Martin, L.1
Schilder, R.2
-
19
-
-
0142009696
-
The influence of microvessel density on ovarian carcinogenesis
-
Stone, P.J.; Goodheart, M.J.; Rose, S.L.; DeYoung, B.R.; Buller, R.E. The influence of microvessel density on ovarian carcinogenesis. Gynecol. Oncol. 2003, 90, 566-571.
-
(2003)
Gynecol. Oncol.
, vol.90
, pp. 566-571
-
-
Stone, P.J.1
Goodheart, M.J.2
Rose, S.L.3
Deyoung, B.R.4
Buller, R.E.5
-
20
-
-
18844363423
-
The relationship of molecular markers of p53 function and angiogenesis to prognosis of stage I epithelial ovarian cancer
-
Goodheart, M.J.; Ritchie, J.M.; Rose, S.L.; Fruehauf, J.P.; DeYoung, B.R.; Buller, R.E. The relationship of molecular markers of p53 function and angiogenesis to prognosis of stage I epithelial ovarian cancer. Clin. Cancer Res. 2005, 11, 3733-3742.
-
(2005)
Clin. Cancer Res.
, vol.11
, pp. 3733-3742
-
-
Goodheart, M.J.1
Ritchie, J.M.2
Rose, S.L.3
Fruehauf, J.P.4
Deyoung, B.R.5
Buller, R.E.6
-
21
-
-
33847355587
-
Vascular endothelial growth factor gene polymorphisms are associated with prognosis in ovarian cancer
-
Hefler, L.A.; Mustea, A.; Konsgen, D.; Concin, N.; Tanner, B.; Strick, R.; Heinze, G.; Grimm, C.; Schuster, E.; Tempfer, C., et al. Vascular endothelial growth factor gene polymorphisms are associated with prognosis in ovarian cancer. Clin. Cancer Res. 2007, 13, 898-901.
-
(2007)
Clin. Cancer Res.
, vol.13
, pp. 898-901
-
-
Hefler, L.A.1
Mustea, A.2
Konsgen, D.3
Concin, N.4
Tanner, B.5
Strick, R.6
Heinze, G.7
Grimm, C.8
Schuster, E.9
Tempfer, C.10
-
22
-
-
0345060442
-
Vascular endothelial growth factor-trap decreases tumor burden, inhibits ascites, and causes dramatic vascular remodeling in an ovarian cancer model
-
Byrne, A.T.; Ross, L.; Holash, J.; Nakanishi, M.; Hu, L.; Hofmann, J.I.; Yancopoulos, G.D.; Jaffe, R.B. Vascular endothelial growth factor-trap decreases tumor burden, inhibits ascites, and causes dramatic vascular remodeling in an ovarian cancer model. Clin. Cancer Res. 2003, 9, 5721-5728.
-
(2003)
Clin. Cancer Res.
, vol.9
, pp. 5721-5728
-
-
Byrne, A.T.1
Ross, L.2
Holash, J.3
Nakanishi, M.4
Hu, L.5
Hofmann, J.I.6
Yancopoulos, G.D.7
Jaffe, R.B.8
-
23
-
-
34248592589
-
Modulation of angiogenic phenotype alters tumorigenicity in rat ovarian epithelial cells
-
Schumacher, J.J.; Dings, R.P.; Cosin, J.; Subramanian, I.V.; Auersperg, N.; Ramikrishnan, S. Modulation of angiogenic phenotype alters tumorigenicity in rat ovarian epithelial cells. Cancer Res. 2007, 67, 3683-3690.
-
(2007)
Cancer Res.
, vol.67
, pp. 3683-3690
-
-
Schumacher, J.J.1
Dings, R.P.2
Cosin, J.3
Subramanian, I.V.4
Auersperg, N.5
Ramikrishnan, S.6
-
24
-
-
41849092178
-
Angiogenesis as a strategic target for ovarian cancer therapy
-
Spannuth, W.A.; Sood, A.K.; Coleman, R.L. Angiogenesis as a strategic target for ovarian cancer therapy. Nat. Clin. Pract. Oncol. 2008, 5, 194-204.
-
(2008)
Nat. Clin. Pract. Oncol.
, vol.5
, pp. 194-204
-
-
Spannuth, W.A.1
Sood, A.K.2
Coleman, R.L.3
-
25
-
-
34548447618
-
Antiangiogenic therapy for ovarian cancer
-
Rosa, D.D.; Clamp, A.R.; Collinson, F.; Jayson, G.C. Antiangiogenic therapy for ovarian cancer. Curr. Opin. Oncol. 2007, 19, 497-505.
-
(2007)
Curr. Opin. Oncol.
, vol.19
, pp. 497-505
-
-
Rosa, D.D.1
Clamp, A.R.2
Collinson, F.3
Jayson, G.C.4
-
26
-
-
0031719516
-
Role of vascular endothelial growth factor in ovarian cancer: Inhibition of ascites formation by immunoneutralization
-
Mesiano, S.; Ferrara, N.; Jaffe, R.B. Role of vascular endothelial growth factor in ovarian cancer: inhibition of ascites formation by immunoneutralization. Am. J. Pathol. 1998, 153, 1249-1256.
-
(1998)
Am. J. Pathol.
, vol.153
, pp. 1249-1256
-
-
Mesiano, S.1
Ferrara, N.2
Jaffe, R.B.3
-
27
-
-
0036168948
-
Inhibition of phosphatidylinositol 3'-kinase increases efficacy of paclitaxel in vitro and in vivo ovarian cancer models
-
Hu, L.; Hofmann, J.; Lu, Y.; Mills, G.B.; Jaffe, R.B. Inhibition of phosphatidylinositol 3'-kinase increases efficacy of paclitaxel in vitro and in vivo ovarian cancer models. Cancer Res. 2002, 62, 1087-1092.
-
(2002)
Cancer Res.
, vol.62
, pp. 1087-1092
-
-
Hu, L.1
Hofmann, J.2
Lu, Y.3
Mills, G.B.4
Jaffe, R.B.5
-
28
-
-
59449084872
-
Maintenance treatment with bevacizumab prolongs survival in an in vivo ovarian cancer model
-
Mabuchi, S.; Terai, Y.; Morishige, K.; Tanabe-Kimura, A.; Sasaki, H.; Kanemura, M.; Tsunetoh, S.; Tanaka, Y.; Sakata, M.; Burger, R.A., et al. Maintenance treatment with bevacizumab prolongs survival in an in vivo ovarian cancer model. Clin. Cancer Res. 2008, 14, 7781-7789.
-
(2008)
Clin. Cancer Res.
, vol.14
, pp. 7781-7789
-
-
Mabuchi, S.1
Terai, Y.2
Morishige, K.3
Tanabe-Kimura, A.4
Sasaki, H.5
Kanemura, M.6
Tsunetoh, S.7
Tanaka, Y.8
Sakata, M.9
Burger, R.A.10
-
29
-
-
36849056497
-
Phase II study of bevacizumab in patients with platinum-resistant ovarian cancer or peritoneal serous cancer
-
Cannistra, S.A.; Matulonis, U.A.; Penson, R.T.; Hambleton, J.; Dupont, J.; Mackey, H.; Douglas, J.; Burger, R.A.; Armstrong, D.; Wenham, R., et al. Phase II study of bevacizumab in patients with platinum-resistant ovarian cancer or peritoneal serous cancer. J. Clin. Oncol. 2007, 25, 5180-5186.
-
(2007)
J. Clin. Oncol.
, vol.25
, pp. 5180-5186
-
-
Cannistra, S.A.1
Matulonis, U.A.2
Penson, R.T.3
Hambleton, J.4
Dupont, J.5
Mackey, H.6
Douglas, J.7
Burger, R.A.8
Armstrong, D.9
Wenham, R.10
-
30
-
-
33748475636
-
The use of bevacizumab to palliate symptomatic ascites in patients with refractory ovarian carcinoma
-
Numnum, T.M.; Rocconi, R.P.; Whitworth, J.; Barnes, M.N. The use of bevacizumab to palliate symptomatic ascites in patients with refractory ovarian carcinoma. Gynecol. Oncol. 2006, 102, 425-428.
-
(2006)
Gynecol. Oncol.
, vol.102
, pp. 425-428
-
-
Numnum, T.M.1
Rocconi, R.P.2
Whitworth, J.3
Barnes, M.N.4
-
31
-
-
33745923690
-
Salvage bevacizumab (rhuMAB VEGF)-based therapy after multiple prior cytotoxic regimens in advanced refractory epithelial ovarian cancer
-
Monk, B.J.; Han, E.; Josephs-Cowan, C.A.; Pugmire, G.; Burger, R.A. Salvage bevacizumab (rhuMAB VEGF)-based therapy after multiple prior cytotoxic regimens in advanced refractory epithelial ovarian cancer. Gynecol. Oncol. 2006, 102, 140-144.
-
(2006)
Gynecol. Oncol.
, vol.102
, pp. 140-144
-
-
Monk, B.J.1
Han, E.2
Josephs-Cowan, C.A.3
Pugmire, G.4
Burger, R.A.5
-
32
-
-
36849019301
-
Phase II trial of bevacizumab in persistent or recurrent epithelial ovarian cancer or primary peritoneal cancer: A Gynecologic Oncology Group Study
-
Burger, R.A.; Sill, M.W.; Monk, B.J.; Greer, B.E.; Sorosky, J.I. Phase II trial of bevacizumab in persistent or recurrent epithelial ovarian cancer or primary peritoneal cancer: a Gynecologic Oncology Group Study. J. Clin. Oncol. 2007, 25, 5165-5171.
-
(2007)
J. Clin. Oncol.
, vol.25
, pp. 5165-5171
-
-
Burger, R.A.1
Sill, M.W.2
Monk, B.J.3
Greer, B.E.4
Sorosky, J.I.5
-
33
-
-
37849035249
-
Phase II clinical trial of bevacizumab and low-dose metronomic oral cyclophosphamide in recurrent ovarian cancer: A trial of the California, Chicago, and Princess Margaret Hospital phase II consortia
-
Garcia, A.A.; Hirte, H.; Fleming, G.; Yang, D.; Tsao-Wei, D.D.; Roman, L.; Groshen, S.; Swenson, S.; Markland, F.; Gandara, D., et al. Phase II clinical trial of bevacizumab and low-dose metronomic oral cyclophosphamide in recurrent ovarian cancer: a trial of the California, Chicago, and Princess Margaret Hospital phase II consortia. J. Clin. Oncol. 2008, 26, 76-82.
-
(2008)
J. Clin. Oncol.
, vol.26
, pp. 76-82
-
-
Garcia, A.A.1
Hirte, H.2
Fleming, G.3
Yang, D.4
Tsao-Wei, D.D.5
Roman, L.6
Groshen, S.7
Swenson, S.8
Markland, F.9
Gandara, D.10
-
34
-
-
43449107359
-
A multi-institutional evaluation of factors predictive of toxicity and efficacy of bevacizumab for recurrent ovarian cancer
-
Wright, J.D.; Secord, A.A.; Numnum, T.M.; Rocconi, R.P.; Powell, M.A.; Berchuck, A.; Alvarez, R.D.; Gibb, R.K.; Trinkaus, K.; Rader, J.S., et al. A multi-institutional evaluation of factors predictive of toxicity and efficacy of bevacizumab for recurrent ovarian cancer. Int. J. Gynecol. Cancer 2008, 18, 400-406.
-
(2008)
Int. J. Gynecol. Cancer
, vol.18
, pp. 400-406
-
-
Wright, J.D.1
Secord, A.A.2
Numnum, T.M.3
Rocconi, R.P.4
Powell, M.A.5
Berchuck, A.6
Alvarez, R.D.7
Gibb, R.K.8
Trinkaus, K.9
Rader, J.S.10
-
35
-
-
34447258681
-
Tumor microenvironment abnormalities: Causes, consequences, and strategies to normalize
-
Fukumura, D.; Jain, R.K. Tumor microenvironment abnormalities: causes, consequences, and strategies to normalize. J. Cell Biochem. 2007, 101, 937-949.
-
(2007)
J. Cell Biochem.
, vol.101
, pp. 937-949
-
-
Fukumura, D.1
Jain, R.K.2
-
36
-
-
0034048358
-
Less is more, regularly: Metronomic dosing of cytotoxic drugs can target tumor angiogenesis in mice
-
Hanahan, D.; Bergers, G.; Bergsland, E. Less is more, regularly: metronomic dosing of cytotoxic drugs can target tumor angiogenesis in mice. J. Clin. Invest. 2000, 105, 1045-1047.
-
(2000)
J. Clin. Invest.
, vol.105
, pp. 1045-1047
-
-
Hanahan, D.1
Bergers, G.2
Bergsland, E.3
-
37
-
-
0034087691
-
Continuous low-dose therapy with vinblastine and VEGF receptor-2 antibody induces sustained tumor regression without overt toxicity
-
Klement, G.; Baruchel, S.; Rak, J.; Man, S.; Clark, K.; Hicklin, D.J.; Bohlen, P.; Kerbel, R.S. Continuous low-dose therapy with vinblastine and VEGF receptor-2 antibody induces sustained tumor regression without overt toxicity. J. Clin. Invest. 2000, 105, R15-R24.
-
(2000)
J. Clin. Invest.
, vol.105
-
-
Klement, G.1
Baruchel, S.2
Rak, J.3
Man, S.4
Clark, K.5
Hicklin, D.J.6
Bohlen, P.7
Kerbel, R.S.8
-
38
-
-
33846441659
-
Metronomic chemotherapy enhances the efficacy of antivascular therapy in ovarian cancer
-
Kamat, A.A.; Kim, T.J.; Landen, C.N., Jr.; Lu, C.; Han, L.Y.; Lin, Y.G.; Merritt, W.M.; Thaker, P.H.; Gershenson, D.M.; Bischoff, F.Z., et al. Metronomic chemotherapy enhances the efficacy of antivascular therapy in ovarian cancer. Cancer Res. 2007, 67, 281-288.
-
(2007)
Cancer Res.
, vol.67
, pp. 281-288
-
-
Kamat, A.A.1
Kim, T.J.2
Landen Jr., C.N.3
Lu, C.4
Han, L.Y.5
Lin, Y.G.6
Merritt, W.M.7
Thaker, P.H.8
Gershenson, D.M.9
Bischoff, F.Z.10
-
39
-
-
35348904080
-
Bevacizumab plus cyclophosphamide in heavily pretreated patients with recurrent ovarian cancer
-
Chura, J.C.; van Iseghem, K.; Downs, L.S., Jr.; Carson, L.F.; Judson, P.L. Bevacizumab plus cyclophosphamide in heavily pretreated patients with recurrent ovarian cancer. Gynecol. Oncol. 2007, 107, 326-330.
-
(2007)
Gynecol. Oncol.
, vol.107
, pp. 326-330
-
-
Chura, J.C.1
van Iseghem, K.2
Downs Jr., L.S.3
Carson, L.F.4
Judson, P.L.5
-
40
-
-
34447298651
-
A phase II study of outpatient first-line paclitaxel, carboplatin, and bevacizumab for advanced-stage epithelial ovarian, peritoneal, and fallopian tube cancer
-
Micha, J.P.; Goldstein, B.H.; Rettenmaier, M.A.; Genesen, M.; Graham, C.; Bader, K.; Lopez, K.L.; Nickle, M.; Brown, J.V., III. A phase II study of outpatient first-line paclitaxel, carboplatin, and bevacizumab for advanced-stage epithelial ovarian, peritoneal, and fallopian tube cancer. Int. J. Gynecol. Cancer 2007, 17, 771-776.
-
(2007)
Int. J. Gynecol. Cancer
, vol.17
, pp. 771-776
-
-
Micha, J.P.1
Goldstein, B.H.2
Rettenmaier, M.A.3
Genesen, M.4
Graham, C.5
Bader, K.6
Lopez, K.L.7
Nickle, M.8
Brown III, J.V.9
-
41
-
-
36849054884
-
Safety of maintenance bevacizumab after first-line chemotherapy for advanced ovarian and müllerian cancers
-
Abstr. 5517
-
Campos, S.M.; Dizon, D.S.; Cannistra, S.A.; Roche, M.; Krasner, C.N.; Berlin, S.T.; Horowitz, N.S.; DiSilvestro, P.; Matulonis, U.A.; Penson, R.T. Safety of maintenance bevacizumab after first-line chemotherapy for advanced ovarian and müllerian cancers. J. Clin. Oncol. 2007, 25(18S), Abstr. 5517.
-
(2007)
J. Clin. Oncol.
, vol.25
, Issue.18 S
-
-
Campos, S.M.1
Dizon, D.S.2
Cannistra, S.A.3
Roche, M.4
Krasner, C.N.5
Berlin, S.T.6
Horowitz, N.S.7
Disilvestro, P.8
Matulonis, U.A.9
Penson, R.T.10
-
42
-
-
0037208589
-
Randomized Trial Comparing Bevacizumab Plus Fluorouracil (FU)/Leucovorin (LV) With FU/LV Alone in Patients With Metastatic Colorectal Cancer
-
Kabbinavar, F.; Hurwitz, H.I.; Fehrenbacher, L.; Meropol, N.J.; Novotny, W.F.; Lieberman, G.; Griffing, S.; Bergsland, E. Phase II, Randomized Trial Comparing Bevacizumab Plus Fluorouracil (FU)/Leucovorin (LV) With FU/LV Alone in Patients With Metastatic Colorectal Cancer. J. Clin. Oncol. 2003, 21, 60-65.
-
(2003)
J. Clin. Oncol.
, vol.21
, pp. 60-65
-
-
Kabbinavar, F.1
Hurwitz, H.I.2
Fehrenbacher, L.3
Meropol, N.J.4
Novotny, W.F.5
Lieberman, G.6
Griffing, S.7
Bergsland, E.8
Phase, I.I.9
-
43
-
-
36849005801
-
VEGF-Trap for patients (pts) with recurrent platinum-resistant epithelial ovarian cancer (EOC): Preliminary results of a randomized, multicenter phase II study
-
Abstr. 5508
-
Tew, W.P.; Colombo, N.; Ray-Coquard, I.; Oza, A.; del Campo, J.; Scambia, G.; Spriggs, D. VEGF-Trap for patients (pts) with recurrent platinum-resistant epithelial ovarian cancer (EOC): Preliminary results of a randomized, multicenter phase II study. J. Clin. Oncol. 2007, 25(18S), Abstr. 5508.
-
(2007)
J. Clin. Oncol.
, vol.25
, Issue.18 S
-
-
Tew, W.P.1
Colombo, N.2
Ray-Coquard, I.3
Oza, A.4
del Campo, J.5
Scambia, G.6
Spriggs, D.7
-
44
-
-
58149248099
-
A phase II study of sunitinib (SU11248) in patients (pts) with recurrent epithelial ovarian, fallopian tube or primary peritoneal carcinoma - NCIC CTG IND 185
-
Abstr. 5522
-
Biagi, J.J.; Oza, A.M.; Grimshaw, R.; Ellard, S.L.; Lee, U.; Sederias, J.; Ivy, S.P.; Eisenhauer, E.A. A phase II study of sunitinib (SU11248) in patients (pts) with recurrent epithelial ovarian, fallopian tube or primary peritoneal carcinoma - NCIC CTG IND 185. J. Clin. Oncol. 2008, 26(suppl), Abstr. 5522.
-
(2008)
J. Clin. Oncol.
, vol.26
, Issue.SUPPL.
-
-
Biagi, J.J.1
Oza, A.M.2
Grimshaw, R.3
Ellard, S.L.4
Lee, U.5
Sederias, J.6
Ivy, S.P.7
Eisenhauer, E.A.8
-
45
-
-
58149257819
-
Cediranib (AZD2171) is an active agent in recurrent epithelial ovarian cancer
-
Abstr. 5501
-
Matulonis, U.A.; Berlin, S.T.; Krasner, C.N.; Tyburski, K.; Lee, J.; Roche, M.; Ivy, S.P.; Lenahan, C.; King, M.; Penson, R.T. Cediranib (AZD2171) is an active agent in recurrent epithelial ovarian cancer. J. Clin. Oncol. 2008, 26(suppl), Abstr. 5501.
-
(2008)
J. Clin. Oncol.
, vol.26
, Issue.SUPPL.
-
-
Matulonis, U.A.1
Berlin, S.T.2
Krasner, C.N.3
Tyburski, K.4
Lee, J.5
Roche, M.6
Ivy, S.P.7
Lenahan, C.8
King, M.9
Penson, R.T.10
-
46
-
-
58149225750
-
Phase II trial of sorafenib in persistent or recurrent epithelial ovarian cancer (EOC) or primary peritoneal cancer (PPC): A Gynecologic Oncology Group (GOG) study
-
Abstr. 5537
-
Matei, D.; Sill, M.W.; DeGeest, K.; Bristow, R.E. Phase II trial of sorafenib in persistent or recurrent epithelial ovarian cancer (EOC) or primary peritoneal cancer (PPC): A Gynecologic Oncology Group (GOG) study. J. Clin. Oncol. 2008, 26(suppl), Abstr. 5537.
-
(2008)
J. Clin. Oncol.
, vol.26
, Issue.SUPPL.
-
-
Matei, D.1
Sill, M.W.2
Degeest, K.3
Bristow, R.E.4
-
47
-
-
36549038661
-
Pazopanib (GW786034) is active in women with advanced epithelial ovarian, fallopian tube and peritoneal cancers: Initial results of a phase II study
-
Abstr. 5561
-
Friedlander, M.; Hancock, K.C.; Benigno, B.; Rischin, D.; Messing, M.; Stringer, C.A.; Tay, E.H.; Kathman, S.; Matthys, G.; Lager, J.J. Pazopanib (GW786034) is active in women with advanced epithelial ovarian, fallopian tube and peritoneal cancers: Initial results of a phase II study. J. Clin. Oncol. 2007, 25(18S), Abstr. 5561.
-
(2007)
J. Clin. Oncol.
, vol.25
, Issue.18 S
-
-
Friedlander, M.1
Hancock, K.C.2
Benigno, B.3
Rischin, D.4
Messing, M.5
Stringer, C.A.6
Tay, E.H.7
Kathman, S.8
Matthys, G.9
Lager, J.J.10
-
48
-
-
33644509244
-
Phase II trial of imatinib mesylate in patients with recurrent platinum- and taxane-resistant epithelial ovarian and primary peritoneal cancers
-
Coleman, R.L.; Broaddus, R.R.; Bodurka, D.C.; Wolf, J.K.; Burke, T.W.; Kavanagh, J.J.; Levenback, C.F.; Gershenson, D.M. Phase II trial of imatinib mesylate in patients with recurrent platinum- and taxane-resistant epithelial ovarian and primary peritoneal cancers. Gynecol. Oncol. 2006, 101, 126-131.
-
(2006)
Gynecol. Oncol.
, vol.101
, pp. 126-131
-
-
Coleman, R.L.1
Broaddus, R.R.2
Bodurka, D.C.3
Wolf, J.K.4
Burke, T.W.5
Kavanagh, J.J.6
Levenback, C.F.7
Gershenson, D.M.8
-
49
-
-
34547160422
-
A prospective analysis of imatinib-induced c-KIT modulation in ovarian cancer: A phase II clinical study with proteomic profiling
-
Posadas, E.M.; Kwitkowski, V.; Kotz, H.L.; Espina, V.; Minasian, L.; Tchabo, N.; Premkumar, A.; Hussain, M.M.; Chang, R.; Steinberg, S.M., et al. A prospective analysis of imatinib-induced c-KIT modulation in ovarian cancer: a phase II clinical study with proteomic profiling. Cancer 2007, 110, 309-317.
-
(2007)
Cancer
, vol.110
, pp. 309-317
-
-
Posadas, E.M.1
Kwitkowski, V.2
Kotz, H.L.3
Espina, V.4
Minasian, L.5
Tchabo, N.6
Premkumar, A.7
Hussain, M.M.8
Chang, R.9
Steinberg, S.M.10
-
50
-
-
58149219264
-
A phase II study of cediranib (AZD2171) in recurrent or persistent ovarian, peritoneal or fallopian tube cancer: Final results of a PMH, Chicago and California consortia trial
-
Abstr. 5521
-
Hirte, H.W.; Vidal, L.; Fleming, G.F.; Sugimoto, A.K.; Morgan, R.J.; Biagi, J.J.; Wang, L.; McGill, S.; Ivy, S.P.; Oza, A.M. A phase II study of cediranib (AZD2171) in recurrent or persistent ovarian, peritoneal or fallopian tube cancer: Final results of a PMH, Chicago and California consortia trial. J. Clin. Oncol. 2008, 26(suppl), Abstr. 5521.
-
(2008)
J. Clin. Oncol.
, vol.26
, Issue.SUPPL.
-
-
Hirte, H.W.1
Vidal, L.2
Fleming, G.F.3
Sugimoto, A.K.4
Morgan, R.J.5
Biagi, J.J.6
Wang, L.7
McGill, S.8
Ivy, S.P.9
Oza, A.M.10
-
51
-
-
49249113484
-
Combination targeted therapy with sorafenib and bevacizumab results in enhanced toxicity and antitumor activity
-
Azad, N.S.; Posadas, E.M.; Kwitkowski, V.E.; Steinberg, S.M.; Jain, L.; Annunziata, C.M.; Minasian L.; Sarosy, G.; Kotz, H.L.; Premkumar, A., et al. Combination targeted therapy with sorafenib and bevacizumab results in enhanced toxicity and antitumor activity. J. Clin. Oncol. 2008, 26, 3709-3714.
-
(2008)
J. Clin. Oncol.
, vol.26
, pp. 3709-3714
-
-
Azad, N.S.1
Posadas, E.M.2
Kwitkowski, V.E.3
Steinberg, S.M.4
Jain, L.5
Annunziata, C.M.6
Minasian, L.7
Sarosy, G.8
Kotz, H.L.9
Premkumar, A.10
-
52
-
-
33746911955
-
Combining targeted agents: Blocking the epidermal growth factor and vascular endothelial growth factor pathways
-
Sandler, A.; Herbst, R. Combining targeted agents: blocking the epidermal growth factor and vascular endothelial growth factor pathways. Clin. Cancer Res. 2006, 12, 4421s-4425s.
-
(2006)
Clin. Cancer Res.
, vol.12
-
-
Sandler, A.1
Herbst, R.2
-
53
-
-
45549099056
-
Efficacy and safety of bevacizumab plus erlotinib for patients with recurrent ovarian, primary peritoneal, and fallopian tube cancer: A trial of the Chicago, PMH, and California Phase II Consortia
-
Nimeiri, H.S.; Oza, A.M.; Morgan, R.J.; Friberg, G.; Kasza, K.; Faoro, L.; Salgia, R.; Stadler, W.M.; Vokes, E.E.; Fleming, G.F. Efficacy and safety of bevacizumab plus erlotinib for patients with recurrent ovarian, primary peritoneal, and fallopian tube cancer: a trial of the Chicago, PMH, and California Phase II Consortia. Gynecol. Oncol. 2008, 110, 49-55.
-
(2008)
Gynecol. Oncol.
, vol.110
, pp. 49-55
-
-
Nimeiri, H.S.1
Oza, A.M.2
Morgan, R.J.3
Friberg, G.4
Kasza, K.5
Faoro, L.6
Salgia, R.7
Stadler, W.M.8
Vokes, E.E.9
Fleming, G.F.10
-
54
-
-
59949102930
-
A randomized phase IIIB trial of chemotherapy, bevacizumab, and panitumumab compared with chemotherapy and bevacizumab alone for metastatic colorectal cancer
-
Hecht, J.R.; Mitchell, E.; Chidiac, T.; Scroggin, C.; Hagenstad, C.; Spigel, D.; Marshall, J.; Cohn, A.; McCollum, D.; Stella, P et al. A randomized phase IIIB trial of chemotherapy, bevacizumab, and panitumumab compared with chemotherapy and bevacizumab alone for metastatic colorectal cancer. J. Clin. Oncol. 2009, 27, 672-680.
-
(2009)
J. Clin. Oncol.
, vol.27
, pp. 672-680
-
-
Hecht, J.R.1
Mitchell, E.2
Chidiac, T.3
Scroggin, C.4
Hagenstad, C.5
Spigel, D.6
Marshall, J.7
Cohn, A.8
McCollum, D.9
Stella, P.10
-
55
-
-
60749109735
-
A phase I study of combretastatin A4 phosphate (CA4P) and bevacizumab in subjects with advanced solid tumors
-
Abstr. 3550
-
Nathan, P.D.; Judson, I.; Padhani, A.; Harris, A.; Carden, C.P.; Smythe, J.; Collins, D.; Leach, M.; Walicke, P.; Rustin, G.J. A phase I study of combretastatin A4 phosphate (CA4P) and bevacizumab in subjects with advanced solid tumors. J. Clin. Oncol. 2008, 26(suppl), Abstr. 3550.
-
(2008)
J. Clin. Oncol.
, vol.26
, Issue.SUPPL.
-
-
Nathan, P.D.1
Judson, I.2
Padhani, A.3
Harris, A.4
Carden, C.P.5
Smythe, J.6
Collins, D.7
Leach, M.8
Walicke, P.9
Rustin, G.J.10
-
56
-
-
33749005405
-
Therapy-induced acute recruitment of circulating endothelial progenitor cells to tumors
-
Shaked, Y.; Ciarrocchi, A.; Franco, M.; Lee, C.R.; Man, S.; Cheung, A.M.; Hicklin, D.J.; Chaplin, D.; Foster, F.S.; Benezra, R. et al. Therapy-induced acute recruitment of circulating endothelial progenitor cells to tumors. Science 2006, 313, 1785-1787.
-
(2006)
Science
, vol.313
, pp. 1785-1787
-
-
Shaked, Y.1
Ciarrocchi, A.2
Franco, M.3
Lee, C.R.4
Man, S.5
Cheung, A.M.6
Hicklin, D.J.7
Chaplin, D.8
Foster, F.S.9
Benezra, R.10
-
57
-
-
68049108414
-
Vascular disrupting agents: A novel mechanism of action in the battle against non-small cell lung cancer
-
Gridelli, C.; Rossi, A.; Maione, P.; Rossi, E.; Castaldo, V.; Sacco, P.C.; Colantuoni, G. Vascular disrupting agents: a novel mechanism of action in the battle against non-small cell lung cancer. Oncologist 2009, 14, 612-620.
-
(2009)
Oncologist
, vol.14
, pp. 612-620
-
-
Gridelli, C.1
Rossi, A.2
Maione, P.3
Rossi, E.4
Castaldo, V.5
Sacco, P.C.6
Colantuoni, G.7
-
58
-
-
76449086344
-
Combretastatin A-4 phosphate (CA4P) carboplatin and paclitaxel in patients with platinum-resistant ovarian cancer: Final phase II trial results
-
Abstr. 5502
-
Zweifel, M.; Jayson, G.; Reed, N.; Osborne, R.; Hassan, B.; Shrreves, G.; Poupard, L.; Walicke, A.; Balkissoon, J.; Chaplin, D., et al. Combretastatin A-4 phosphate (CA4P) carboplatin and paclitaxel in patients with platinum-resistant ovarian cancer: Final phase II trial results. J. Clin. Oncol. 2009, 27(15S), Abstr. 5502.
-
(2009)
J. Clin. Oncol.
, vol.27
, Issue.15 S
-
-
Zweifel, M.1
Jayson, G.2
Reed, N.3
Osborne, R.4
Hassan, B.5
Shrreves, G.6
Poupard, L.7
Walicke, A.8
Balkissoon, J.9
Chaplin, D.10
-
59
-
-
66149121478
-
Risk of gastrointestinal perforation in patients with cancer treated with bevacizumab: A meta-analysis
-
Hapani, S.; Chu, D.; Wu, S. Risk of gastrointestinal perforation in patients with cancer treated with bevacizumab: a meta-analysis. Lancet Oncol. 2009, 10, 559-568.
-
(2009)
Lancet Oncol.
, vol.10
, pp. 559-568
-
-
Hapani, S.1
Chu, D.2
Wu, S.3
-
60
-
-
33947311852
-
What is the risk of bowel perforation associated with bevacizumab therapy in ovarian cancer?
-
Han, E.S.; Monk, B.J. What is the risk of bowel perforation associated with bevacizumab therapy in ovarian cancer? Gynecol. Oncol. 2007, 105, 3-6.
-
(2007)
Gynecol. Oncol.
, vol.105
, pp. 3-6
-
-
Han, E.S.1
Monk, B.J.2
-
61
-
-
33846638744
-
Risks of proteinuria and hypertension with bevacizumab, an antibody against vascular endothelial growth factor: Systematic review and meta-analysis
-
Zhu, X.; Wu, S.; Dahut, W.L.; Parikh, C.R. Risks of proteinuria and hypertension with bevacizumab, an antibody against vascular endothelial growth factor: Systematic review and meta-analysis. Am. J. Kidney Dis. 2007, 49, 186-193.
-
(2007)
Am. J. Kidney Dis.
, vol.49
, pp. 186-193
-
-
Zhu, X.1
Wu, S.2
Dahut, W.L.3
Parikh, C.R.4
-
62
-
-
0042343801
-
A randomized trial of bevacizumab, an antivascular endothelial growth factor antibody, for metastatic renal cancer
-
Yang, J.C.; Haworth, L.; Sherry, R.M.; Hwu, P.; Schwartzentruber, D.J.; Topalian, S.L.; Steinberg, S.M.; Chen, H.X.; Rosenberg, S.A. A randomized trial of bevacizumab, an antivascular endothelial growth factor antibody, for metastatic renal cancer. N. Engl. J. Med. 2003, 349, 427-434.
-
(2003)
N. Engl. J. Med.
, vol.349
, pp. 427-434
-
-
Yang, J.C.1
Haworth, L.2
Sherry, R.M.3
Hwu, P.4
Schwartzentruber, D.J.5
Topalian, S.L.6
Steinberg, S.M.7
Chen, H.X.8
Rosenberg, S.A.9
-
63
-
-
33645449812
-
Mechanisms of hypertension associated with BAY 43-9006
-
Veronese, M.L.; Mosenkis, A.; Flaherty, K.T.; Gallagher, M.; Stevenson, J.P.; Townsend, R.R.; O'Dwyer, P.J. Mechanisms of hypertension associated with BAY 43-9006. J. Clin. Oncol. 2006, 24, 1363-1369.
-
(2006)
J. Clin. Oncol.
, vol.24
, pp. 1363-1369
-
-
Veronese, M.L.1
Mosenkis, A.2
Flaherty, K.T.3
Gallagher, M.4
Stevenson, J.P.5
Townsend, R.R.6
O'Dwyer, P.J.7
-
64
-
-
0035913613
-
Epidermal growth factor receptor signaling and the invasive phenotype of ovarian carcinoma cells
-
Alper, O.; Bergmann-Leitner, E.S.; Bennett, T.A.; Hacker, N.F.; Stromberg, K.; Stetler- Stevenson, W.G. Epidermal growth factor receptor signaling and the invasive phenotype of ovarian carcinoma cells. J. Nat. Cancer Inst. 2001, 93, 1375-1384.
-
(2001)
J. Nat. Cancer Inst.
, vol.93
, pp. 1375-1384
-
-
Alper, O.1
Bergmann-Leitner, E.S.2
Bennett, T.A.3
Hacker, N.F.4
Stromberg, K.5
Stetler-Stevenson, W.G.6
-
65
-
-
0035027576
-
The growth factor receptors HER-2/neu and EGFR, their relationship, and their effects on the prognosis in early stage (FIGO I-II) epithelial ovarian carcinoma
-
Skirnisdottir, I.; Sorbe, B.; Seidal, T. The growth factor receptors HER-2/neu and EGFR, their relationship, and their effects on the prognosis in early stage (FIGO I-II) epithelial ovarian carcinoma. Int. J. Gynecol. Cancer 2001, 11, 119-129.
-
(2001)
Int. J. Gynecol. Cancer
, vol.11
, pp. 119-129
-
-
Skirnisdottir, I.1
Sorbe, B.2
Seidal, T.3
-
66
-
-
0041629450
-
Status of epidermal growth factor receptor antagonists in the biology and treatment of cancer
-
Mendelsohn, J.; Baselga, J. Status of epidermal growth factor receptor antagonists in the biology and treatment of cancer. J. Clin. Oncol. 2003, 21, 2787-2799.
-
(2003)
J. Clin. Oncol.
, vol.21
, pp. 2787-2799
-
-
Mendelsohn, J.1
Baselga, J.2
-
67
-
-
0028819660
-
Biological efficacy of a chimeric antibody to the epidermal growth factor receptor in a human tumor xenograft model
-
Goldstein, N.I.; Prewett, M.; Zuklys, K.; Rockwell, P.; Mendelsohn, J. Biological efficacy of a chimeric antibody to the epidermal growth factor receptor in a human tumor xenograft model. Clin. Cancer Res. 1995, 1, 1311-1318.
-
(1995)
Clin. Cancer Res.
, vol.1
, pp. 1311-1318
-
-
Goldstein, N.I.1
Prewett, M.2
Zuklys, K.3
Rockwell, P.4
Mendelsohn, J.5
-
68
-
-
33846950834
-
A phase II trial of EMD72000 (matuzumab), a humanized anti-EGFR monoclonal antibody, in patients with platinum-resistant ovarian and primary peritoneal malignancies
-
Seiden, M.V.; Burris, H.A.; Matulonis, U.; Hall, J.B.; Armstrong, D.K.; Speyer, J.; Weber, J.D.; Muggia, F. A phase II trial of EMD72000 (matuzumab), a humanized anti-EGFR monoclonal antibody, in patients with platinum-resistant ovarian and primary peritoneal malignancies. Gynecol. Oncol. 2007, 104, 727-731.
-
(2007)
Gynecol. Oncol.
, vol.104
, pp. 727-731
-
-
Seiden, M.V.1
Burris, H.A.2
Matulonis, U.3
Hall, J.B.4
Armstrong, D.K.5
Speyer, J.6
Weber, J.D.7
Muggia, F.8
-
69
-
-
8444221534
-
Administration of CI-1033, an Irreversible PanerbB Tyrosine Kinase Inhibitor, Is Feasible on a 7-Day On, 7-Day Off Schedule
-
Calvo, E.; Tolcher, A.W.; Hammond, L.A.; Patnaik, A.; de Bono, J.S.; Eiseman, I.A.; Olson, S.C.; Lenehan, P.F.; McCreery, H.; Lorusso, P., et al. Administration of CI-1033, an Irreversible PanerbB Tyrosine Kinase Inhibitor, Is Feasible on a 7-Day On, 7-Day Off Schedule. Clin. Cancer Res. 2004, 10, 7112-7120.
-
(2004)
Clin. Cancer Res.
, vol.10
, pp. 7112-7120
-
-
Calvo, E.1
Tolcher, A.W.2
Hammond, L.A.3
Patnaik, A.4
de Bono, J.S.5
Eiseman, I.A.6
Olson, S.C.7
Lenehan, P.F.8
McCreery, H.9
Lorusso, P.10
-
70
-
-
0001069404
-
Phase 2 Evaluation of OSI-774, a Potent Oral Antagonist of the EGFR-TK in Patients with Advanced Ovarian Carcinoma
-
(Proc ASCO 2001), Abstr. 831
-
Finkler, N.; Gordon, A.; Crozier, M.; Edwards, R.; Figueroa, J.; Garcia, A.; Hainsworth, J.; Irwin, D.; Silberman, S.; Allen, L., et al. Phase 2 Evaluation of OSI-774, a Potent Oral Antagonist of the EGFR-TK in Patients with Advanced Ovarian Carcinoma. J. Clin. Oncol. 2001, 20(Proc ASCO 2001), Abstr. 831.
-
(2001)
J. Clin. Oncol.
, vol.20
-
-
Finkler, N.1
Gordon, A.2
Crozier, M.3
Edwards, R.4
Figueroa, J.5
Garcia, A.6
Hainsworth, J.7
Irwin, D.8
Silberman, S.9
Allen, L.10
-
71
-
-
27744556593
-
A Phase II Study of Cetuximab/Paclitaxel/Carboplatin for the Initial Treatment of Advanced Stage Ovarian, Primary Peritoneal, and Fallopian Tube Cancer
-
Abstr. 2047
-
Aghajanian, C.; Sabbatini, P.; Derosa, F.; Gerst, S.; Spriggs, D.R.; Dupont, J.; Hensley, M.L.; Pezzulli, S.; Konner, J.; Schilder, R.J. A Phase II Study of Cetuximab/Paclitaxel/Carboplatin for the Initial Treatment of Advanced Stage Ovarian, Primary Peritoneal, and Fallopian Tube Cancer. J. Clin. Oncol. 2005, 23(16S), Abstr. 2047.
-
(2005)
J. Clin. Oncol.
, vol.23
, Issue.16 S
-
-
Aghajanian, C.1
Sabbatini, P.2
Derosa, F.3
Gerst, S.4
Spriggs, D.R.5
Dupont, J.6
Hensley, M.L.7
Pezzulli, S.8
Konner, J.9
Schilder, R.J.10
-
72
-
-
42649145667
-
Wild-type KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancer
-
Amado, R.G.; Wolf, M.; Peeters, M.; van Cutsem, E.; Siena, S.; Freeman, D.J.; Juan, T.; Sikorski, R.; Suggs, S.; Radinsky, R., et al. Wild-type KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancer. J. Clin. Oncol. 2008, 26, 1626-1634.
-
(2008)
J. Clin. Oncol.
, vol.26
, pp. 1626-1634
-
-
Amado, R.G.1
Wolf, M.2
Peeters, M.3
van Cutsem, E.4
Siena, S.5
Freeman, D.J.6
Juan, T.7
Sikorski, R.8
Suggs, S.9
Radinsky, R.10
-
73
-
-
1942469352
-
Ovarian tumorigenesis: A proposed model based on morphological and molecular genetic analysis
-
Shih, I.M.; Kurman, R.J. Ovarian tumorigenesis: a proposed model based on morphological and molecular genetic analysis. Am. J. Pathol 2004, 164, 1511-1518.
-
(2004)
Am. J. Pathol.
, vol.164
, pp. 1511-1518
-
-
Shih, I.M.1
Kurman, R.J.2
-
74
-
-
23044511620
-
Phase II study of gefitinib in patients with relapsed or persistent ovarian or primary peritoneal carcinoma and evaluation of epidermal growth factor receptor mutations and immunohistochemical expression: A Gynecologic Oncology Group Study
-
Schilder, R.J.; Sill, M.W.; Chen, X.; Darcy, K.M.; Decesare, S.L.; Lewandowski, G.; Lee, R.B.; Arciero, C.A.; Wu, H.; Godwin, A.K. Phase II study of gefitinib in patients with relapsed or persistent ovarian or primary peritoneal carcinoma and evaluation of epidermal growth factor receptor mutations and immunohistochemical expression: a Gynecologic Oncology Group Study. Clin. Cancer Res. 2005, 11, 5539-5548.
-
(2005)
Clin. Cancer Res.
, vol.11
, pp. 5539-5548
-
-
Schilder, R.J.1
Sill, M.W.2
Chen, X.3
Darcy, K.M.4
Decesare, S.L.5
Lewandowski, G.6
Lee, R.B.7
Arciero, C.A.8
Wu, H.9
Godwin, A.K.10
-
75
-
-
0037440042
-
Evaluation of monoclonal humanized anti-HER2 antibody, trastuzumab, in patients with recurrent or refractory ovarian or primary peritoneal carcinoma with overexpression of HER2: A phase II trial of the Gynecologic Oncology Group
-
Bookman, M.A.; Darcy, K.M.; Clarke-Pearson, D.; Boothby, R.A.; Horowitz, I.R. Evaluation of monoclonal humanized anti-HER2 antibody, trastuzumab, in patients with recurrent or refractory ovarian or primary peritoneal carcinoma with overexpression of HER2: a phase II trial of the Gynecologic Oncology Group. J. Clin. Oncol. 2003, 21, 283-90.
-
(2003)
J. Clin. Oncol.
, vol.21
, pp. 283-290
-
-
Bookman, M.A.1
Darcy, K.M.2
Clarke-Pearson, D.3
Boothby, R.A.4
Horowitz, I.R.5
-
76
-
-
33749003463
-
Clinical activity of pertuzumab (rhuMAb 2C4), a HER dimerization inhibitor, in advanced ovarian cancer: Potential predictive relationship with tumor HER2 activation status
-
Gordon, M.S.; Matei, D.; Aghajanian, C.; Matulonis, U.A.; Brewer, M.; Fleming, G.F.; Hainsworth, J.D.; Garcia, A.A.; Pegram, M.D.; Schilder, R.J., et al. Clinical activity of pertuzumab (rhuMAb 2C4), a HER dimerization inhibitor, in advanced ovarian cancer: potential predictive relationship with tumor HER2 activation status. J. Clin. Oncol. 2006, 24, 4324-4332.
-
(2006)
J. Clin. Oncol.
, vol.24
, pp. 4324-4332
-
-
Gordon, M.S.1
Matei, D.2
Aghajanian, C.3
Matulonis, U.A.4
Brewer, M.5
Fleming, G.F.6
Hainsworth, J.D.7
Garcia, A.A.8
Pegram, M.D.9
Schilder, R.J.10
-
77
-
-
60749110876
-
HER pathway gene expression analysis in a phase II study of pertuzumab + gemcitabine vs. gemcitabine + placebo in patients with platinum-resistant epithelial ovarian cancer
-
Abstr. 5522
-
Amler, L.; Makhija, S.; Januario, T.; Matulonis, U.A.; Strauss, A.; Dizon, D.S.; Sliwkowski, M.X.; Dolezal, M.; Tong, B.; Paton, V. HER pathway gene expression analysis in a phase II study of pertuzumab + gemcitabine vs. gemcitabine + placebo in patients with platinum-resistant epithelial ovarian cancer. J. Clin. Oncol. 2008, 26(15S), Abstr. 5522.
-
(2008)
J. Clin. Oncol.
, vol.26
, Issue.15 S
-
-
Amler, L.1
Makhija, S.2
Januario, T.3
Matulonis, U.A.4
Strauss, A.5
Dizon, D.S.6
Sliwkowski, M.X.7
Dolezal, M.8
Tong, B.9
Paton, V.10
-
78
-
-
33745867638
-
Poly(ADP-ribose): Novel functions for an old molecule
-
Schreiber, V.; Dantzer, F.; Ame, J.C.; de Murcia, G. Poly(ADP-ribose): novel functions for an old molecule. Nat Rev Mol Cell Biol 2006, 7, 517-528.
-
(2006)
Nat Rev Mol Cell Biol.
, vol.7
, pp. 517-528
-
-
Schreiber, V.1
Dantzer, F.2
Ame, J.C.3
de Murcia, G.4
-
79
-
-
4344685333
-
The PARP superfamily
-
Ame, J.C.; Spenlehauer, C.; de Murcia, G. The PARP superfamily. Bioessays 2004, 26, 882-893.
-
(2004)
Bioessays
, vol.26
, pp. 882-893
-
-
Ame, J.C.1
Spenlehauer, C.2
de Murcia, G.3
-
80
-
-
17244375049
-
Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase
-
Bryant, H.E.; Schultz, N.; Thomas, H.D.; Parker, K.M.; Flower, D.; Lopez, E.; Kyle, S.; Meuth, M.; Curtin, N.J.; Helleday, T. Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase. Nature 2005, 434, 913-917.
-
(2005)
Nature
, vol.434
, pp. 913-917
-
-
Bryant, H.E.1
Schultz, N.2
Thomas, H.D.3
Parker, K.M.4
Flower, D.5
Lopez, E.6
Kyle, S.7
Meuth, M.8
Curtin, N.J.9
Helleday, T.10
-
81
-
-
17244373777
-
Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy
-
Farmer, H.; McCabe, N.; Lord, C.J.; Tutt, A.N.; Johnson, D.A.; Richardson, T.B.; Santarosa, M.; Dillon, K.J.; Hickson, I.; Knights, C., et al. Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy. Nature 2005, 434, 917-921.
-
(2005)
Nature
, vol.434
, pp. 917-921
-
-
Farmer, H.1
McCabe, N.2
Lord, C.J.3
Tutt, A.N.4
Johnson, D.A.5
Richardson, T.B.6
Santarosa, M.7
Dillon, K.J.8
Hickson, I.9
Knights, C.10
-
82
-
-
28544433970
-
Efficient deletion of normal Brca2-deficient intestinal epithelium by poly(ADP-ribose) polymerase inhibition models potential prophylactic therapy
-
Hay, T.; Jenkins, H.; Sansom, O.J.; Martin, N.M.; Smith, G.C.; Clarke, A.R. Efficient deletion of normal Brca2-deficient intestinal epithelium by poly(ADP-ribose) polymerase inhibition models potential prophylactic therapy. Cancer Res. 2005, 65, 10145-10148.
-
(2005)
Cancer Res.
, vol.65
, pp. 10145-10148
-
-
Hay, T.1
Jenkins, H.2
Sansom, O.J.3
Martin, N.M.4
Smith, G.C.5
Clarke, A.R.6
-
83
-
-
34249024488
-
Phase I pharmacokinetic (PK) and pharmacodynamic (PD) evaluation of a small molecule inhibitor of Poly ADP-Ribose Polymerase (PARP), KU-0059436 (Ku) in patients (p) with advanced tumours
-
Abstr. 3022
-
Fong, P.C.; Spicer, J.; Reade, S.; Reid, A.; Vidal, L.; Schellens, J.H.; Tutt, A.; Harris, P.A.; Kaye, S.; DeBono, J.S. Phase I pharmacokinetic (PK) and pharmacodynamic (PD) evaluation of a small molecule inhibitor of Poly ADP-Ribose Polymerase (PARP), KU-0059436 (Ku) in patients (p) with advanced tumours. J. Clin. Oncol. 2006, 24(18S), Abstr. 3022.
-
(2006)
J. Clin. Oncol.
, vol.24
, Issue.18 S
-
-
Fong, P.C.1
Spicer, J.2
Reade, S.3
Reid, A.4
Vidal, L.5
Schellens, J.H.6
Tutt, A.7
Harris, P.A.8
Kaye, S.9
Debono, J.S.10
-
84
-
-
33746100822
-
Exploiting the DNA repair defect in BRCA mutant cells in the design of new therapeutic strategies for cancer
-
Tutt, A.N.; Lord, C.J.; McCabe, N.; Farmer, H.; Turner, N.; Martin, N.M.; Jackson, S.P.; Smith, G.C.; Ashworth, A. Exploiting the DNA repair defect in BRCA mutant cells in the design of new therapeutic strategies for cancer. Cold Spring Harb. Symp. Quant. Biol. 2005, 70, 139-148.
-
(2005)
Cold Spring Harb Symp. Quant. Biol.
, vol.70
, pp. 139-148
-
-
Tutt, A.N.1
Lord, C.J.2
McCabe, N.3
Farmer, H.4
Turner, N.5
Martin, N.M.6
Jackson, S.P.7
Smith, G.C.8
Ashworth, A.9
-
85
-
-
55749096953
-
AZD2281 (KU-0059436), a PARP (poly ADP-ribose polymerase) inhibitor with single agent anticancer activity in patients with BRCA deficient ovarian cancer: Results from a phase I study
-
Abstr. 5510
-
Fong, P.C.; Boss, D.S.; Carden, C.P.; Roelvink, M.; De Greve, J.; Gourley, C.M.; Carmichael, J.; De Bono, J.S.; Schellens, J.H.; Kaye, S.B. AZD2281 (KU-0059436), a PARP (poly ADP-ribose polymerase) inhibitor with single agent anticancer activity in patients with BRCA deficient ovarian cancer: Results from a phase I study. J. Clin. Oncol. 2008, 26(suppl), Abstr. 5510.
-
(2008)
J. Clin. Oncol.
, vol.26
, Issue.SUPPL.
-
-
Fong, P.C.1
Boss, D.S.2
Carden, C.P.3
Roelvink, M.4
de Greve, J.5
Gourley, C.M.6
Carmichael, J.7
de Bono, J.S.8
Schellens, J.H.9
Kaye, S.B.10
-
86
-
-
68149161777
-
Phase II trial of the oral PARP inhibitor olaparib (AZD2281) in BRCA-deficient advanced ovarian cancer
-
Abstr. 5500
-
Audeh, M.W.; Penson, R.T.; Friedlander, M.; Powell, B.; Bell-McGuinn, K.M.; Scott, C.; Weitzel, J.N.; Carmichael, J.; Tutt, A. Phase II trial of the oral PARP inhibitor olaparib (AZD2281) in BRCA-deficient advanced ovarian cancer. J. Clin. Oncol. 2009, 27(15S), Abstr. 5500.
-
(2009)
J. Clin. Oncol.
, vol.27
, Issue.15 S
-
-
Audeh, M.W.1
Penson, R.T.2
Friedlander, M.3
Powell, B.4
Bell-McGuinn, K.M.5
Scott, C.6
Weitzel, J.N.7
Carmichael, J.8
Tutt, A.9
-
87
-
-
4944229642
-
Hallmarks of 'BRCAness' in sporadic cancers
-
Turner, N.; Tutt, A.; Ashworth, A. Hallmarks of 'BRCAness' in sporadic cancers. Nat. Rev. Cancer 2004, 4, 814-819.
-
(2004)
Nat. Rev. Cancer
, vol.4
, pp. 814-819
-
-
Turner, N.1
Tutt, A.2
Ashworth, A.3
-
88
-
-
39549091276
-
Ovarian carcinomas with genetic and epigenetic BRCA1 loss have distinct molecular abnormalities
-
Press, J.Z.; De Luca, A.; Boyd, N.; Young, S.; Troussard, A.; Ridge, Y.; Kaurah, P.; Kalloger, S.E.; Blood, K.A.; Smith, M., et al. Ovarian carcinomas with genetic and epigenetic BRCA1 loss have distinct molecular abnormalities. BMC Cancer 2008, 8, 17.
-
(2008)
BMC Cancer
, vol.8
, pp. 17
-
-
Press, J.Z.1
de Luca, A.2
Boyd, N.3
Young, S.4
Troussard, A.5
Ridge, Y.6
Kaurah, P.7
Kalloger, S.E.8
Blood, K.A.9
Smith, M.10
-
89
-
-
32044466838
-
Exploiting the PI3K/AKT pathway for cancer drug discovery
-
Hennessy, B.T.; Smith, D.L.; Ram, P.T.; Lu, Y.; Mills, G.B. Exploiting the PI3K/AKT pathway for cancer drug discovery. Nat. Rev. Drug Discov. 2005, 4, 988-1004.
-
(2005)
Nat. Rev. Drug Discov.
, vol.4
, pp. 988-1004
-
-
Hennessy, B.T.1
Smith, D.L.2
Ram, P.T.3
Lu, Y.4
Mills, G.B.5
-
90
-
-
65549167833
-
Targeting the mTOR signaling network for cancer therapy
-
Meric-Bernstam, F.; Gonzalez-Angulo, A.M. Targeting the mTOR signaling network for cancer therapy. J. Clin. Oncol. 2009, 27, 2278-2287.
-
(2009)
J. Clin. Oncol.
, vol.27
, pp. 2278-2287
-
-
Meric-Bernstam, F.1
Gonzalez-Angulo, A.M.2
-
91
-
-
0032590011
-
PIK3CA is implicated as an oncogene in ovarian cancer
-
Shayesteh, L.; Lu, Y.; Kuo, W.L.; Baldocchi, R.; Godfrey, T.; Collins, C.; Pinkel, D.; Powell, B.; Mills, G.B.; Gray, J.W. PIK3CA is implicated as an oncogene in ovarian cancer. Nat. Genet. 1999, 21, 99-102.
-
(1999)
Nat. Genet.
, vol.21
, pp. 99-102
-
-
Shayesteh, L.1
Lu, Y.2
Kuo, W.L.3
Baldocchi, R.4
Godfrey, T.5
Collins, C.6
Pinkel, D.7
Powell, B.8
Mills, G.B.9
Gray, J.W.10
-
92
-
-
7444250290
-
Mutation of the PIK3CA gene in ovarian and breast cancer
-
Campbell, I.G.; Russell, S.E.; Choong, D.Y.; Montgomery, K.G.; Ciavarella, M.L.; Hooi, C.S.; Cristiano, B.E.; Pearson, R.B.; Phillips, W.A. Mutation of the PIK3CA gene in ovarian and breast cancer. Cancer Res. 2004, 64, 7678-7681.
-
(2004)
Cancer Res.
, vol.64
, pp. 7678-7681
-
-
Campbell, I.G.1
Russell, S.E.2
Choong, D.Y.3
Montgomery, K.G.4
Ciavarella, M.L.5
Hooi, C.S.6
Cristiano, B.E.7
Pearson, R.B.8
Phillips, W.A.9
-
93
-
-
0032523808
-
Frequent PTEN/MMAC mutations in endometrioid but not serous or mucinous epithelial ovarian tumors
-
Obata, K.; Morland, S.J.; Watson, R.H.; Hitchcock, A.; Chenevix-Trench, G.; Thomas, E.J.; Campbell, I.G. Frequent PTEN/MMAC mutations in endometrioid but not serous or mucinous epithelial ovarian tumors. Cancer Res. 1998, 58, 2095-2097.
-
(1998)
Cancer Res.
, vol.58
, pp. 2095-2097
-
-
Obata, K.1
Morland, S.J.2
Watson, R.H.3
Hitchcock, A.4
Chenevix-Trench, G.5
Thomas, E.J.6
Campbell, I.G.7
-
94
-
-
33646918756
-
Novel biologic terapies for the treatment of endometrial cancer
-
Wolf, J.; Slomovitz, B.M. Novel biologic terapies for the treatment of endometrial cancer. Int. J. Gynecol. Cancer 2005, 15, 411.
-
(2005)
Int. J. Gynecol. Cancer
, vol.15
, pp. 411
-
-
Wolf, J.1
Slomovitz, B.M.2
-
95
-
-
24944480788
-
The Akt-mTOR tango and its relevance to cancer
-
Hay, N. The Akt-mTOR tango and its relevance to cancer. Cancer Cell 2005, 8, 179-83.
-
(2005)
Cancer Cell
, vol.8
, pp. 179-183
-
-
Hay, N.1
-
96
-
-
4143111260
-
AKT and mTOR phosphorylation is frequently detected in ovarian cancer and can be targeted to disrupt ovarian tumor cell growth
-
Altomare, D.A.; Wang, H.Q.; Skele, K.L.; De Rienzo, A.; Klein-Szanto, A.J.; Godwin, A.K.; Testa, J.R. AKT and mTOR phosphorylation is frequently detected in ovarian cancer and can be targeted to disrupt ovarian tumor cell growth. Oncogene 2004, 23, 5853-5857.
-
(2004)
Oncogene
, vol.23
, pp. 5853-5857
-
-
Altomare, D.A.1
Wang, H.Q.2
Skele, K.L.3
de Rienzo, A.4
Klein-Szanto, A.J.5
Godwin, A.K.6
Testa, J.R.7
-
97
-
-
62549099008
-
The VEGF pathway and the AKT/mTOR/p70S6K1 signalling pathway in human epithelial ovarian cancer
-
Trinh, X.B.; Tjalma, W.A.; Vermeulen, P.B.; van den Eynden, G.; van der Auwera, I.; van Laere, S.J.; Helleman, J.; Berns, E.M.; Dirix, L.Y.; van Dam, P.A. The VEGF pathway and the AKT/mTOR/p70S6K1 signalling pathway in human epithelial ovarian cancer. Br. J. Cancer 2009, 100, 971-978.
-
(2009)
Br. J. Cancer
, vol.100
, pp. 971-978
-
-
Trinh, X.B.1
Tjalma, W.A.2
Vermeulen, P.B.3
van den Eynden, G.4
van der Auwera, I.5
van Laere, S.J.6
Helleman, J.7
Berns, E.M.8
Dirix, L.Y.9
van Dam, P.A.10
-
98
-
-
38849091289
-
Activation of fibronectin/PI-3K/Akt2 leads to chemoresistance to docetaxel by regulating survivin protein expression in ovarian and breast cancer cells
-
Xing, H.; Weng, D.; Chen, G.; Tao, W.; Zhu, T.; Yang, X.; Meng, L.; Wang, S.; Lu, Y.; Ma, D. Activation of fibronectin/PI-3K/Akt2 leads to chemoresistance to docetaxel by regulating survivin protein expression in ovarian and breast cancer cells. Cancer Lett. 2008, 261, 108-119.
-
(2008)
Cancer Lett.
, vol.261
, pp. 108-119
-
-
Xing, H.1
Weng, D.2
Chen, G.3
Tao, W.4
Zhu, T.5
Yang, X.6
Meng, L.7
Wang, S.8
Lu, Y.9
Ma, D.10
-
99
-
-
37349060695
-
Akt promotes cisplatin resistance in human ovarian cancer cells through inhibition of p53 phosphorylation and nuclear function
-
Fraser, M.; Bai, T.; Tsang, B.K. Akt promotes cisplatin resistance in human ovarian cancer cells through inhibition of p53 phosphorylation and nuclear function. Int. J. Cancer 2008, 122, 534-546.
-
(2008)
Int. J. Cancer
, vol.122
, pp. 534-546
-
-
Fraser, M.1
Bai, T.2
Tsang, B.K.3
-
100
-
-
6044259204
-
Targeting mammalian target of rapamycin synergistically enhances chemotherapy-induced cytotoxicity in breast cancer cells
-
Mondesire, W.H.; Jian, W.; Zhang, H.; Ensor, J.; Hung, M.C.; Mills, G.B.; Meric-Bernstam, F. Targeting mammalian target of rapamycin synergistically enhances chemotherapy-induced cytotoxicity in breast cancer cells. Clin. Cancer Res. 2004, 10, 7031-7042.
-
(2004)
Clin. Cancer Res
, vol.10
, pp. 7031-7042
-
-
Mondesire, W.H.1
Jian, W.2
Zhang, H.3
Ensor, J.4
Hung, M.C.5
Mills, G.B.6
Meric-Bernstam, F.7
-
101
-
-
46849093151
-
Dynamic contrast-enhanced magnetic resonance imaging: A useful tool for characterizing ovarian epithelial tumors
-
Thomassin-Naggara, I.; Darai, E.; Cuenod, C.A.; Rouzier, R.; Callard, P.; Bazot, M. Dynamic contrast-enhanced magnetic resonance imaging: a useful tool for characterizing ovarian epithelial tumors. J. Magn. Reson. Imaging 2008, 28, 111-120.
-
(2008)
J. Magn. Reson. Imaging
, vol.28
, pp. 111-120
-
-
Thomassin-Naggara, I.1
Darai, E.2
Cuenod, C.A.3
Rouzier, R.4
Callard, P.5
Bazot, M.6
-
102
-
-
0020559574
-
A radioimmunoassay using a monoclonal antibody to monitor the course of epithelial ovarian cancer
-
Bast, R.C., Jr.; Klug, T.L.; St John, E.; Jenison, E.; Niloff, J.M.; Lazarus, H.; Berkowitz, R.S.; Leavitt, T.; Griffiths, C.T.; Parker, L., et al. A radioimmunoassay using a monoclonal antibody to monitor the course of epithelial ovarian cancer. N. Engl. J. Med. 1983, 309, 883-887.
-
(1983)
N. Engl. J. Med.
, vol.309
, pp. 883-887
-
-
Bast Jr., R.C.1
Klug, T.L.2
St John, E.3
Jenison, E.4
Niloff, J.M.5
Lazarus, H.6
Berkowitz, R.S.7
Leavitt, T.8
Griffiths, C.T.9
Parker, L.10
-
103
-
-
1242334764
-
Biologic and immunologic therapies for ovarian cancer
-
Berek, J.S.; Schultes, B.C.; Nicodemus, C.F. Biologic and immunologic therapies for ovarian cancer. J. Clin. Oncol. 2003, 21(10S), 168s-174s.
-
(2003)
J. Clin. Oncol.
, vol.21
, Issue.10 S
-
-
Berek, J.S.1
Schultes, B.C.2
Nicodemus, C.F.3
-
104
-
-
0029001252
-
Antiidiotype induction therapy: Evidence for the induction of immune response through the idiotype network in patients with ovarian cancer after administration of anti-CA125 murine monoclonal antibody B43.13
-
Madiyalakan, R.; Sykes, T.R.; Dharampaul, S.; Sykes, C.J.; Baum, R.P.; Hör, G.; Noujaim, A.A. Antiidiotype induction therapy: evidence for the induction of immune response through the idiotype network in patients with ovarian cancer after administration of anti-CA125 murine monoclonal antibody B43.13. Hybridoma 1995, 14, 199-203.
-
(1995)
Hybridoma
, vol.14
, pp. 199-203
-
-
Madiyalakan, R.1
Sykes, T.R.2
Dharampaul, S.3
Sykes, C.J.4
Baum, R.P.5
Hör, G.6
Noujaim, A.A.7
-
105
-
-
14244250598
-
A pilot phase 2 study of oregovomab murine monoclonal antibody to CA125 as an immunotherapeutic agent for recurrent ovarian cancer
-
Ehlen, T.G.; Hoskins, P.J.; Miller, D.; Whiteside, T.L.; Nicodemus, C.F.; Schultes, B.C.; Swenerton, K.D. A pilot phase 2 study of oregovomab murine monoclonal antibody to CA125 as an immunotherapeutic agent for recurrent ovarian cancer. Int. J. Gynecol. Cancer 2005, 15, 1023-1034.
-
(2005)
Int. J. Gynecol. Cancer
, vol.15
, pp. 1023-1034
-
-
Ehlen, T.G.1
Hoskins, P.J.2
Miller, D.3
Whiteside, T.L.4
Nicodemus, C.F.5
Schultes, B.C.6
Swenerton, K.D.7
-
106
-
-
3142670929
-
CA125- and tumor-specific T-cell responses correlate with prolonged survival in oregovomab-treated recurrent ovarian cancer patients
-
Gordon, A.N.; Schultes, B.C.; Gallion, H.; Edwards, R.; Whiteside, T.L.; Cermak, J.M.; Nicodemus, C.F. CA125- and tumor-specific T-cell responses correlate with prolonged survival in oregovomab-treated recurrent ovarian cancer patients. Gynecol. Oncol 2004, 94, 340-351.
-
(2004)
Gynecol. Oncol.
, vol.94
, pp. 340-351
-
-
Gordon, A.N.1
Schultes, B.C.2
Gallion, H.3
Edwards, R.4
Whiteside, T.L.5
Cermak, J.M.6
Nicodemus, C.F.7
-
107
-
-
4444383336
-
Randomized, placebo-controlled study of oregovomab for consolidation of clinical remission in patients with advanced ovarian cancer
-
Berek, J.S.; Taylor, P.T.; Gordon, A.; Cunningham, M.J.; Finkler, N.; Orr, J., Jr.; Rivkin, S.; Schultes, B.C.; Whiteside, T.L.; Nicodemus, C.F. Randomized, placebo-controlled study of oregovomab for consolidation of clinical remission in patients with advanced ovarian cancer. J. Clin. Oncol. 2004, 22(17), 3507-3516.
-
(2004)
J. Clin. Oncol.
, vol.22
, Issue.17
, pp. 3507-3516
-
-
Berek, J.S.1
Taylor, P.T.2
Gordon, A.3
Cunningham, M.J.4
Finkler, N.5
Orr Jr., J.6
Rivkin, S.7
Schultes, B.C.8
Whiteside, T.L.9
Nicodemus, C.F.10
-
108
-
-
58549092734
-
Prospective evaluation of front-line chemo-immunotherapy (C-IT) with oregovomab (2 alternative dosing schedules) carboplatin-paclitaxel (C-P) in advanced ovarian cancer (OC)
-
Abstr. 3024
-
Braly, P.; Chu, C.; Collins, Y.; Edwards, R.; Gordon, A.; McGuire, W.; Smith, L.M.; Nicodemus, C.; Method, M. Prospective evaluation of front-line chemo-immunotherapy (C-IT) with oregovomab (2 alternative dosing schedules) carboplatin-paclitaxel (C-P) in advanced ovarian cancer (OC). J. Clin. Oncol. 2007, 25(18S), Abstr. 3024.
-
(2007)
J. Clin. Oncol.
, vol.25
, Issue.18 S
-
-
Braly, P.1
Chu, C.2
Collins, Y.3
Edwards, R.4
Gordon, A.5
McGuire, W.6
Smith, L.M.7
Nicodemus, C.8
Method, M.9
-
109
-
-
59149100151
-
Intraperitoneal treatment of malignant ascites due to epithelial tumors with catumaxomab, A phase II/III study
-
Abstr. 3000
-
Parsons, S.; Murawa, P.X.; Koralewski, P.; Kutarska, E.; Kolesnik, O.O.; Stroehlein, M.A.; Lahr, A.; Jaeger, M.; Heiss, M.M. Intraperitoneal treatment of malignant ascites due to epithelial tumors with catumaxomab, A phase II/III study. J. Clin. Oncol. 2008, 26(suppl), Abstr. 3000.
-
(2008)
J. Clin. Oncol.
, vol.26
, Issue.SUPPL.
-
-
Parsons, S.1
Murawa, P.X.2
Koralewski, P.3
Kutarska, E.4
Kolesnik, O.O.5
Stroehlein, M.A.6
Lahr, A.7
Jaeger, M.8
Heiss, M.M.9
-
110
-
-
32944463897
-
Role of folate receptor genes in reproduction and related cancers
-
Elnakat, H.; Ratnam, M. Role of folate receptor genes in reproduction and related cancers. Front. Biosci. 2006, 11, 506-519.
-
(2006)
Front. Biosci.
, vol.11
, pp. 506-519
-
-
Elnakat, H.1
Ratnam, M.2
-
111
-
-
33947166337
-
Preclinical evaluation of MORAb-003, a humanized monoclonal antibody antagonizing folate receptor-alpha
-
Ebel, W.; Routhier, E.L.; Foley, B.; Jacob, S.; McDonough, J.M.; Patel, R.K.; Turchin, H.A.; Chao, Q.; Kline, J.B.; Old, L.J., et al. Preclinical evaluation of MORAb-003, a humanized monoclonal antibody antagonizing folate receptor-alpha. Cancer Immun. 2007, 7, 6.
-
(2007)
Cancer Immun.
, vol.7
, pp. 6
-
-
Ebel, W.1
Routhier, E.L.2
Foley, B.3
Jacob, S.4
McDonough, J.M.5
Patel, R.K.6
Turchin, H.A.7
Chao, Q.8
Kline, J.B.9
Old, L.J.10
-
112
-
-
59349119253
-
Exploratory phase II efficacy study of MORAb-003, a monoclonal antibody against folate receptor alpha, in platinum-sensitive ovarian cancer in first relapse
-
Abstr. 5500
-
Armstrong, D.K.; Bicher, A.; Coleman, R.L.; Gibbon, D.G.; Glenn, D.; Old, L.; Senzer, N.N.; Schneeweiss, A.; Verheijen, R.H.; White, A.J.; Weil, S. Exploratory phase II efficacy study of MORAb-003, a monoclonal antibody against folate receptor alpha, in platinum-sensitive ovarian cancer in first relapse. J. Clin. Oncol. 2008, 26(suppl), Abstr. 5500.
-
(2008)
J. Clin. Oncol.
, vol.26
, Issue.SUPPL.
-
-
Armstrong, D.K.1
Bicher, A.2
Coleman, R.L.3
Gibbon, D.G.4
Glenn, D.5
Old, L.6
Senzer, N.N.7
Schneeweiss, A.8
Verheijen, R.H.9
White, A.J.10
Weil, S.11
-
113
-
-
29244449017
-
BGC 945, a novel tumor-selective thymidylate synthase inhibitor targeted to alpha-folate receptor-overexpressing tumors
-
Gibbs, D.D.; Theti, D.S.; Wood, N.; Green, M.; Raynaud, F.; Valenti, M.; Forster, M.D.; Mitchell, F.; Bavetsias, V.; Henderson, E., et al. BGC 945, a novel tumor-selective thymidylate synthase inhibitor targeted to alpha-folate receptor-overexpressing tumors. Cancer Res. 2005, 65, 11721-11728.
-
(2005)
Cancer Res.
, vol.65
, pp. 11721-11728
-
-
Gibbs, D.D.1
Theti, D.S.2
Wood, N.3
Green, M.4
Raynaud, F.5
Valenti, M.6
Forster, M.D.7
Mitchell, F.8
Bavetsias, V.9
Henderson, E.10
-
114
-
-
44849093562
-
Oncogene addiction
-
Weinstein, I.B.; Joe, A. Oncogene addiction. Cancer Res. 2008, 68, 3077-3080.
-
(2008)
Cancer Res.
, vol.68
, pp. 3077-3080
-
-
Weinstein, I.B.1
Joe, A.2
-
115
-
-
31544463584
-
Response of ovarian carcinomas to gefitinib-carboplatin-paclitaxel combination is not associated with EGFR kinase domain somatic mutations
-
Lacroix, L.; Pautier, P.; Duvillard, P.; Motté, N.; Saulnier, P.; Bidart, J.M.; Soria, J.C. Response of ovarian carcinomas to gefitinib-carboplatin-paclitaxel combination is not associated with EGFR kinase domain somatic mutations. Int. J. Cancer 2006, 118, 1068-1069.
-
(2006)
Int. J. Cancer
, vol.118
, pp. 1068-1069
-
-
Lacroix, L.1
Pautier, P.2
Duvillard, P.3
Motté, N.4
Saulnier, P.5
Bidart, J.M.6
Soria, J.C.7
-
116
-
-
79952163804
-
-
Gastrointestinal Cancers Symposium, San Francisco, CA, USA, 15-17 January 2009; Abstr. 34
-
Stella, G.; Rojas Llimpe, F.L.; Barone, C.; Falcone, A.; Di Fabio, F.; Lamba, S.; Martoni, A.A.; Siena, S.; Bardelli, A.; Pinto, C. KRAS and BRAF mutational status and response to cetuximab combination therapy in advanced gastric cancer (GC) patients. 2009 Gastrointestinal Cancers Symposium, San Francisco, CA, USA, 15-17 January 2009; Abstr. 34.
-
(2009)
KRAS and BRAF Mutational Status and Response to Cetuximab Combination Therapy in Advanced Gastric Cancer (GC) Patients
-
-
Stella, G.1
Rojas, L.F.L.2
Barone, C.3
Falcone, A.4
di Fabio, F.5
Lamba, S.6
Martoni, A.A.7
Siena, S.8
Bardelli, A.9
Pinto, C.10
-
117
-
-
49249091523
-
Identification and characterization of ovarian cancer-initiating cells from primary human tumors
-
Zhang, S.; Balch, C.; Chan, M.W.; Lai, H.C.; Matei, D.; Schilder, J.M.; Yan, P.S.; Huang, T.H.; Nephew, K.P. Identification and characterization of ovarian cancer-initiating cells from primary human tumors. Cancer Res. 2008, 68, 4311-4320.
-
(2008)
Cancer Res.
, vol.68
, pp. 4311-4320
-
-
Zhang, S.1
Balch, C.2
Chan, M.W.3
Lai, H.C.4
Matei, D.5
Schilder, J.M.6
Yan, P.S.7
Huang, T.H.8
Nephew, K.P.9
-
118
-
-
56749083527
-
Biomarkers in oncology drug development: Rescuers or troublemakers?
-
Marrer, E.; Dieterle, F. Biomarkers in oncology drug development: rescuers or troublemakers? Expert Opin. Drug Metab. Toxicol. 2008, 4, 1391-1402.
-
(2008)
Expert Opin. Drug Metab. Toxicol.
, vol.4
, pp. 1391-1402
-
-
Marrer, E.1
Dieterle, F.2
-
119
-
-
20244378677
-
Phase I clinical study of pertuzumab, a novel HER dimerization inhibitor, in patients with advanced cancer
-
Agus, D.B.; Gordon, M.S.; Taylor, C.; Natale, R.B.; Karlan, B.; Mendelson, D.S.; Press, M.F.; Allison, D.E.; Sliwkowski, M.X.; Lieberman, G., et al. Phase I clinical study of pertuzumab, a novel HER dimerization inhibitor, in patients with advanced cancer. J. Clin. Oncol. 2005, 23, 2534-2543.
-
(2005)
J. Clin. Oncol.
, vol.23
, pp. 2534-2543
-
-
Agus, D.B.1
Gordon, M.S.2
Taylor, C.3
Natale, R.B.4
Karlan, B.5
Mendelson, D.S.6
Press, M.F.7
Allison, D.E.8
Sliwkowski, M.X.9
Lieberman, G.10
-
120
-
-
18844444034
-
A phase Ib trial of erlotinib (E) in combination with docetaxel (D) and carboplatin (C) in untreated ovarian, fallopian tube and primary peritoneal cancers
-
Abstr. 5017
-
Vasey, P.; Kaye, S.; Paul, J.; Rustin, G.; Wilson, R.; Guastalla, J.P.; Pujade-Lauraine, E.; Gore, M.; Gabra, H.; Carty, K. A phase Ib trial of erlotinib (E) in combination with docetaxel (D) and carboplatin (C) in untreated ovarian, fallopian tube and primary peritoneal cancers J. Clin. Oncol. 2004, 22(14S), Abstr. 5017.
-
(2004)
J. Clin. Oncol.
, vol.22
, Issue.14 S
-
-
Vasey, P.1
Kaye, S.2
Paul, J.3
Rustin, G.4
Wilson, R.5
Guastalla, J.P.6
Pujade-Lauraine, E.7
Gore, M.8
Gabra, H.9
Carty, K.10
-
121
-
-
51749114292
-
Report of first-stage accrual for NCI 5886, a phase II study of erlotinib, carboplatin and paclitaxel as first-line treatment of ovarian cancer
-
Abstr. 5076
-
Blank, S.V.; Curtin, J.P.; Goldman, N.A.; Runowicz, C.D.; Speyer, J.L.; Tiersten, A.D.; Dancey, J.; Wadler, S.; Muggia, F.M. Report of first-stage accrual for NCI 5886, a phase II study of erlotinib, carboplatin and paclitaxel as first-line treatment of ovarian cancer. J. Clin. Oncol. 2006, 24(18S), Abstr. 5076.
-
(2006)
J. Clin. Oncol.
, vol.24
, Issue.18 S
-
-
Blank, S.V.1
Curtin, J.P.2
Goldman, N.A.3
Runowicz, C.D.4
Speyer, J.L.5
Tiersten, A.D.6
Dancey, J.7
Wadler, S.8
Muggia, F.M.9
-
122
-
-
45949093468
-
Phase I study of weekly topotecan and gefitinib in patients with platinum-resistant ovarian, peritoneal, or fallopian tube cancer
-
Abstr. 5090
-
Slomovitz, B.M.; Coleman, R.L.; Levenback, C.; Jung, M.; Gershenson, D.M.; Wolf, J. Phase I study of weekly topotecan and gefitinib in patients with platinum-resistant ovarian, peritoneal, or fallopian tube cancer J. Clin. Oncol. 2006, 24(18S), Abstr. 5090.
-
(2006)
J. Clin. Oncol.
, vol.24
, Issue.18 S
-
-
Slomovitz, B.M.1
Coleman, R.L.2
Levenback, C.3
Jung, M.4
Gershenson, D.M.5
Wolf, J.6
-
123
-
-
45949109268
-
Maintenance therapy in epithelial ovarian cancer (EOC): Could EGFR inhibitor- gefitinib be a candidate drug? A pilot study
-
Abstr. 15046
-
Hariprasad, R.; Kumar, L.; Patnaik, R.; Gupta, A.; Kumar, S. Maintenance therapy in epithelial ovarian cancer (EOC): Could EGFR inhibitor- gefitinib be a candidate drug? A pilot study. J. Clin. Oncol. 2006, 24(18S), Abstr. 15046.
-
(2006)
J. Clin. Oncol.
, vol.24
, Issue.18 S
-
-
Hariprasad, R.1
Kumar, L.2
Patnaik, R.3
Gupta, A.4
Kumar, S.5
-
124
-
-
18844397099
-
A phase I-II trial of gefitinib in combination with vinorelbine and oxaliplatin as salvage therapy in women with advanced ovarian cancer (AOC)
-
Abstr. 5020
-
Mavroudis, D.; Efstathiou, E.; Polyzos, A.; Athanasiadis, A.; Milaki, G.; Kastritis, E.; Kalykaki, A.; Saridaki, Z.; Dimopoulos, A.; Georgoulias, V. A phase I-II trial of gefitinib in combination with vinorelbine and oxaliplatin as salvage therapy in women with advanced ovarian cancer (AOC). J. Clin. Oncol. 2004, 22(14S), Abstr. 5020.
-
(2004)
J. Clin. Oncol.
, vol.22
, Issue.14 S
-
-
Mavroudis, D.1
Efstathiou, E.2
Polyzos, A.3
Athanasiadis, A.4
Milaki, G.5
Kastritis, E.6
Kalykaki, A.7
Saridaki, Z.8
Dimopoulos, A.9
Georgoulias, V.10
-
125
-
-
34548415747
-
Phase II trial of anastrazole in combination with gefitinib in women with asymptomatic mullerian cancer
-
Abstr. 5063
-
Krasner, C.N.; Debernardo, R.L.; Findley, M.; Penson, R.; Matulonis, U.; Atkinson, T.; Roche, M.; Seiden, M.V. Phase II trial of anastrazole in combination with gefitinib in women with asymptomatic mullerian cancer J. Clin. Oncol. 2005, 23(16S), Abstr. 5063.
-
(2005)
J. Clin. Oncol.
, vol.23
, Issue.16 S
-
-
Krasner, C.N.1
Debernardo, R.L.2
Findley, M.3
Penson, R.4
Matulonis, U.5
Atkinson, T.6
Roche, M.7
Seiden, M.V.8
-
126
-
-
22744441949
-
A phase I study of GW572016 in patients with solid tumors
-
Abstr. 3048
-
Minami, H.; Nakagawa, K.; Kawada, K.; Mukai, H.; Tahara, M.; Kurata, T.; Uejima, H.; Nogami, T.; Sasaki, Y.; Fukuoka, M. A phase I study of GW572016 in patients with solid tumors J. Clin. Oncol. 2004, 22(14S), Abstr. 3048
-
(2004)
J. Clin. Oncol.
, vol.22
, Issue.14 S
-
-
Minami, H.1
Nakagawa, K.2
Kawada, K.3
Mukai, H.4
Tahara, M.5
Kurata, T.6
Uejima, H.7
Nogami, T.8
Sasaki, Y.9
Fukuoka, M.10
-
127
-
-
15344339405
-
A phase 2, single agent study of CI-1033 administered at two doses in ovarian cancer patients who failed platinum therapy
-
Abstr. 5054
-
Campos, S.M.; Seiden, M.V.; Oza, A.; Plante, M.; Potkul, R.; Hamid, O.; Lenehan, P.; Kaldjian, E.; Jordan, C.; Hirte, H. A phase 2, single agent study of CI-1033 administered at two doses in ovarian cancer patients who failed platinum therapy J. Clin. Oncol. 2004, 22(14S), Abstr. 5054
-
(2004)
J. Clin. Oncol.
, vol.22
, Issue.14 S
-
-
Campos, S.M.1
Seiden, M.V.2
Oza, A.3
Plante, M.4
Potkul, R.5
Hamid, O.6
Lenehan, P.7
Kaldjian, E.8
Jordan, C.9
Hirte, H.10
|