Topical gentamicin does not provide any additional anastomotic strength when combined with fibrin glue

American Journal of Surgery

Volumn 201, Issue 3, 2011, Pages 339-343

  Subhas, Gokulakkrishna ^a   Bhullar, Jasneet Singh ^a   Cook, Jonathan ^a   Shah, Asha ^a   Silberberg, Boris ^a   Andrus, Lee ^a   Decker, Melissa ^a   Mittal, Vijay K ^a  

^a PROVIDENCE HOSPITAL   (United States)

Author keywords

Adhesions; Bursting pressure; Colonic anastomosis; Fibrin glue; Fibroblasts; Gentamicin

Indexed keywords

FIBRIN GLUE; GENTAMICIN;

ADHESION; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; COLON ANASTOMOSIS; CONTROLLED STUDY; FIBROBLAST; HISTOLOGY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SUTURING METHOD; TRANSVERSE COLON;

ADMINISTRATION, TOPICAL; ANASTOMOSIS, SURGICAL; ANASTOMOTIC LEAK; ANIMALS; ANTI-BACTERIAL AGENTS; COLON; DRUG THERAPY, COMBINATION; FIBRIN TISSUE ADHESIVE; GENTAMICINS; HEMOSTATICS; MALE; PRESSURE; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY; SUTURE TECHNIQUES; TISSUE ADHESIVES; TREATMENT FAILURE; WOUND HEALING;

EID: 79952142741     PISSN: 00029610     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.amjsurg.2010.09.022     Document Type: Article

References (12)

1. A.C. van der Ham, W.J. Kort, and I.M. Weijma Effect of antibiotics in fibrin sealant on healing colonic anastomoses in the rat Br J Surg 79 1992 525 528
2. M. Binnebosel, K. Junge, and D.A. Kaemmer Intraperitoneally applied gentamicin increases collagen content and mechanical stability of colon anastomosis in rats Int J Colorectal Dis 24 2009 433 440
3. A. Akgun, S. Kuru, and C. Uraldi Early effects of fibrin sealant on colonic anastomosis in rats: an experimental and case-control study Tech Coloproctol 10 2006 208 214 (Pubitemid 44546802)
4. I. Kanellos, I. Mantzoros, and H. Demetriades Healing of colon anastomoses covered with fibrin glue after immediate postoperative intraperitoneal administration of 5-fluorouracil Dis Colon Rectum 47 2004 510 515 (Pubitemid 38436658)
5. H. Oka, R.C. Harrison, and H.J. Burhenne Effect of a biologic glue on the leakage rate of experimental rectal anastomoses Am J Surg 143 1982 561 564 (Pubitemid 12120501)
6. R.C. Burton, E.S. Hughes, and A.M. Cuthbertson Prophylactic use of gentamicin in colonic and rectal surgery Med J Aust 2 1975 597 599
7. A. Tekos, E. Prodromaki, and E. Papadimou Aminoglycosides suppress tRNA processing in human epidermal keratinocytes in vitro Skin Pharmacol Appl Skin Physiol 16 2003 252 258 (Pubitemid 36649415)
8. D. Wrzesniok, E. Buszman, and E. Karna Melanin potentiates gentamicin-induced inhibition of collagen biosynthesis in human skin fibroblasts Eur J Pharmacol 446 2002 7 13 (Pubitemid 34722552)
9. K. Junge, U. Klinge, and R. Rosch Improved collagen type I/III ratio at the interface of gentamicin-supplemented polyvinlyidenefluoride mesh materials Langenbecks Arch Surg 392 2007 465 471 (Pubitemid 46911416)
10. P. Wang, J. Wang, and W. Zhang Effect of the combination of fibrin glue and growth hormone on intestinal anastomoses in a pig model of traumatic shock associated with peritonitis World J Surg 33 2009 567 576
11. S. Erturk, S. Yuceyar, and M. Temiz Effects of hyaluronic acid-carboxymethylcellulose antiadhesion barrier on ischemic colonic anastomosis: an experimental study Dis Colon Rectum 46 2003 529 534 (Pubitemid 36428051)
12. Y. Li, Y. Bao, and T. Jiang Effect of the combination of fibrin glue and growth hormone on incomplete intestinal anastomoses in a rat model of intra-abdominal sepsis J Surg Res 131 2006 111 117 (Pubitemid 43227592)