Novel and known microsatellite markers within the β-globin cluster to support robust preimplantation genetic diagnosis of β-thalassemia and sickle cell syndromes

Hemoglobin

Volumn 35, Issue 1, 2011, Pages 56-66

  Zachaki, Sophia ^a   Vrettou, Christina ^a   Destouni, Aspasia ^a   Kokkali, Ggeorgia ^a   Traeger Synodinos, Joanne ^a   Kanavakis, Emmanuel ^a,b  

^a UNIVERSITY OF ATHENS   (Greece)

^b St Sophia's Children's Hospital   (Greece)

Author keywords

Thalassemia ( thal); Allele dropout (ADO); Microsatellite repeats; Misdiagnosis; Preimplantation genetic diagnosis (PGD)

Indexed keywords

BETA GLOBIN;

ALLELE; ARTICLE; BETA THALASSEMIA; CLINICAL PROTOCOL; COMPUTER MODEL; EMBRYO; GENE CLUSTER; GENE LOCUS; GENETIC RISK; GENETIC SCREENING; GENOTYPE; GLOBIN GENE; HEMOGLOBINOPATHY; HETEROZYGOSITY; HUMAN; HUMAN CELL; LYMPHOCYTE; MAJOR CLINICAL STUDY; MICROSATELLITE MARKER; MULTIPLEX POLYMERASE CHAIN REACTION; MUTATIONAL ANALYSIS; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PREIMPLANTATION GENETIC DIAGNOSIS; SHORT TANDEM REPEAT; SICKLE CELL ANEMIA;

ALLELES; ANEMIA, SICKLE CELL; BETA-GLOBINS; BETA-THALASSEMIA; BLASTOMERES; CYTOGENETIC ANALYSIS; EMBRYO TRANSFER; FEMALE; GENOTYPE; HETEROZYGOTE; HUMANS; MICROSATELLITE REPEATS; MUTATION; POLYMERASE CHAIN REACTION; PREGNANCY; PREIMPLANTATION DIAGNOSIS; SINGLE-CELL ANALYSIS; SYNDROME;

EID: 79952142429     PISSN: 03630269     EISSN: 1532432X     Source Type: Journal    
DOI: 10.3109/03630269.2010.544620     Document Type: Article

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