Hb S-β-thalassemia: Molecular, hematological and clinical comparisons

Hemoglobin

Volumn 35, Issue 1, 2011, Pages 1-12

  Serjeant, Graham R ^a   Serjeant, Beryl E ^a   Fraser, Raphael A ^b   Hambleton, Ian R ^c   Higgs, Douglas R ^d   Kulozik, Andreas E ^e   Donaldson, Alan ^f  

^a Med Research Council Laboratories   (Jamaica)

^b UNIVERSITY OF THE WEST INDIES   (Jamaica)

^c UNIVERSITY OF THE WEST INDIES   (Jamaica)

^d JOHN RADCLIFFE HOSPITAL   (United Kingdom)

^e UNIVERSITY OF HEIDELBERG   (Germany)

^f ST MICHAEL'S HOSPITAL   (United Kingdom)

Author keywords

+ Thalassemia ( + thal) trait; 0 Thalassemia ( 0 thal) trait; Hb S + thalassemia ( + thal); Hb S 0 thalassemia ( 0 thal); Thalassemia mutations

Indexed keywords

HEMOGLOBIN; HEMOGLOBIN A; HEMOGLOBIN A2; HEMOGLOBIN F; HEMOGLOBIN S; HEMOGLOBIN VARIANT; POLYADENYLIC ACID;

ADOLESCENT; ADULT; APLASTIC CRISIS; ARTICLE; BETA THALASSEMIA; CHILD; CHOLECYSTECTOMY; CLINICAL FEATURE; CODON; CONTROLLED STUDY; DEATH; DISEASE SEVERITY; ERYTHROCYTE; EVALUATION AND FOLLOW UP; FRAMESHIFT MUTATION; GALLSTONE; GENE DELETION; GENE MUTATION; GENETIC TRAIT; HAND FOOT SYNDROME; HEMATOLOGY; HUMAN; HYPERSPLENISM; LEG ULCER; MAJOR CLINICAL STUDY; MEAN CORPUSCULAR HEMOGLOBIN; MEAN CORPUSCULAR VOLUME; MOLECULAR PATHOLOGY; MORBIDITY; MORTALITY; NONSENSE MUTATION; PHENOTYPIC VARIATION; PRIAPISM; RETICULOCYTE; SCHOOL CHILD; SEPTICEMIA; SICKLE CELL BETA THALASSEMIA; SICKLE CELL BETA THALASSEMIA TYPE 1; SICKLE CELL BETA THALASSEMIA TYPE 3; SPLENOMEGALY;

ADULT; ANEMIA, SICKLE CELL; BETA-THALASSEMIA; CHILD; CODON; FETAL HEMOGLOBIN; GENETIC ASSOCIATION STUDIES; HEMATOLOGIC TESTS; HEMOGLOBIN A2; HEMOGLOBINS, ABNORMAL; HUMANS; INFANT, NEWBORN; MUTATION; NEONATAL SCREENING; SEQUENCE ANALYSIS, DNA; SURVIVAL RATE;

EID: 79952138729     PISSN: 03630269     EISSN: 1532432X     Source Type: Journal    
DOI: 10.3109/03630269.2010.546306     Document Type: Article

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