Acute promyelocytic leukemia following chemotherapy for EBV-associated hemophagocytic lymphohistiocytosis

Pediatric Blood and Cancer

Volumn 56, Issue 5, 2011, Pages 850-852

  Sathiyamoorthy, Srividya ^a   Shad, Aziza ^a   Ozdemirli, Metin ^a  

^a GEORGETOWN UNIVERSITY HOSPITAL   (United States)

Author keywords

EBV; Hemophagocytosis; Leukemia; Promyelocytic; Secondary; Therapy related

Indexed keywords

ALANINE AMINOTRANSFERASE; AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; BILIRUBIN GLUCURONIDE; CD15 ANTIGEN; CD33 ANTIGEN; CD4 ANTIGEN; CYCLOSPORIN; CYTARABINE; DAUNORUBICIN; DEXAMETHASONE; EPSTEIN BARR VIRUS ANTIGEN 1; ETOPOSIDE; FERRITIN; FIBRINOGEN; LACTATE DEHYDROGENASE; METHOTREXATE; RETINOIC ACID; TRIACYLGLYCEROL;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANEMIA; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; ASPIRATION BIOPSY; BLOOD CLOTTING DISORDER; BLOOD SMEAR; BONE MARROW BIOPSY; CANCER CHEMOTHERAPY; CASE REPORT; CELL HYPERPLASIA; CERVICAL LYMPH NODE; CHILD; CHROMOSOME 12Q; CHROMOSOME 15; CHROMOSOME 17; CHROMOSOME 22Q; CHROMOSOME ANALYSIS; CHROMOSOME G BAND; DISEASE ASSOCIATION; DISEASE COURSE; DISSEMINATED INTRAVASCULAR CLOTTING; DRUG EFFICACY; ERYTHROCYTE; ERYTHROCYTE TRANSFUSION; FERRITIN BLOOD LEVEL; FEVER; FIBRINOGEN BLOOD LEVEL; FLOW CYTOMETRY; FOLLOW UP; HEMATOCRIT; HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS; HEPATITIS; HEPATOSPLENOMEGALY; HISTIOCYTE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; JAUNDICE; KUPFFER CELL; LACTATE DEHYDROGENASE BLOOD LEVEL; LEUKEMIA REMISSION; LEUKOCYTE COUNT; LIVER BIOPSY; LYMPHADENOPATHY; MALE; NATURAL KILLER CELL; NEUTROPENIA; PANCYTOPENIA; PARTIAL THROMBOPLASTIN TIME; PRESCHOOL CHILD; PRIORITY JOURNAL; PROMYELOCYTE; PROMYELOCYTIC LEUKEMIA; PROTHROMBIN TIME; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; THROMBIN TIME; THROMBOCYTE COUNT; THROMBOCYTE TRANSFUSION; THROMBOCYTOPENIA; TREATMENT RESPONSE; TRIACYLGLYCEROL BLOOD LEVEL;

ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CHROMOSOMES, HUMAN, PAIR 15; CHROMOSOMES, HUMAN, PAIR 17; CYCLOSPORINE; DEXAMETHASONE; EPSTEIN-BARR VIRUS INFECTIONS; ETOPOSIDE; HERPESVIRUS 4, HUMAN; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; INFANT; KARYOTYPING; LEUKEMIA, PROMYELOCYTIC, ACUTE; LYMPHATIC DISEASES; LYMPHOHISTIOCYTOSIS, HEMOPHAGOCYTIC; MALE; ONCOGENE PROTEINS, FUSION; TRANSLOCATION, GENETIC;

EID: 79952132558     PISSN: 15455009     EISSN: 15455017     Source Type: Journal    
DOI: 10.1002/pbc.22718     Document Type: Article

References (20)

1. Swerdlow SHCE, Harris NL, Jaffe ES, et al. WHO classification of tumours of haematopoietic and lymphoid tissues. Lyon: IARC; 2008.
2. Le Deley MC, Leblanc T, Shamsaldin A, et al. Risk of secondary leukemia after a solid tumor in childhood according to the dose of epipodophyllotoxins and anthracyclines: A case-control study by the Societe Francaise d'Oncologie Pediatrique. J Clin Oncol 2003; 21: 1074-1081.
3. Haupt R, Fears TR, Heise A, et al. Risk of secondary leukemia after treatment with etoposide (VP-16) for Langerhans' cell histiocytosis in Italian and Austrian-German populations. Int J Cancer 1997; 71: 9-13.
4. Detourmignies L, Castaigne S, Stoppa AM, et al. Therapy-related acute promyelocytic leukemia: A report on 16 cases. J Clin Oncol 1992; 10: 1430-1435.
5. Hoffmann L, Moller P, Pedersen-Bjergaard J, et al. Therapy-related acute promyelocytic leukemia with t(15;17) (q22;q12) following chemotherapy with drugs targeting DNA topoisomerase II. A report of two cases and a review of the literature. Ann Oncol 1995; 6: 781-788.
6. Kudo K, Yoshida H, Kiyoi H, et al. Etoposide-related acute promyelocytic leukemia. Leukemia 1998; 12: 1171-1175.
7. De Renzo A, Santoro LF, Notaro R, et al. Acute promyelocytic leukemia after treatment for non-Hodgkin's lymphoma with drugs targeting topoisomerase II. Am J Hematol 1999; 60: 300-304.
8. Au WY, Ma SK, Chung LP, et al. Two cases of therapy-related acute promyelocytic leukemia (t-APL) after mantle cell lymphoma and gestational trophoblastic disease. Ann Hematol 2002; 81: 659-661.
9. Martin J, Majumdar G. Platinum compounds and therapy related acute promyelocytic leukemia. Hematol J 2002; 3: 321-323.
10. Mochiduki Y, Muramoto S. Therapy-related acute promyelocytic leukemia with a t(9;22)(q34;q11) and t(15;17)(q22;q11 to approximately 12) subclone. Rinsho Ketsueki 2005; 46: 1218-1222.
11. Henter JI, Horne A, Arico M, et al. HLH-2004: Diagnostic and therapeutic guidelines for hemophagocytic lymphohistiocytosis. Pediatr Blood Cancer 2007; 48: 124-131.
12. Imashuku S. Etoposide-related secondary acute myeloid leukemia (t-AML) in hemophagocytic lymphohistiocytosis. Pediatr Blood Cancer 2007; 48: 121-123.
13. Rudd E, Goransdotter Ericson K, Zheng C, et al. Spectrum and clinical implications of syntaxin 11 gene mutations in familial haemophagocytic lymphohistiocytosis: Association with disease-free remissions and haematopoietic malignancies. J Med Genet 2006; 43: e14.
14. Henter JI, Arico M, Egeler RM, et al. HLH-94: A treatment protocol for hemophagocytic lymphohistiocytosis. HLH study Group of the Histiocyte Society. Med Pediatr Oncol 1997; 28: 342-347.
15. Janka G, zur Stadt U. Familial and acquired hemophagocytic lymphohistiocytosis. Hematology Am Soc Hematol Educ Program 2005; 82-88.
16. Kikuta H, Sakiyama Y. Etoposide (VP-16) inhibits Epstein-Barr virus determined nuclear antigen (EBNA) synthesis. Br J Haematol 1995; 90: 971-973.
17. Matsuzaki A, Inamitsu T, Watanabe T, et al. Acute promyelocytic leukaemia in a patient treated with etoposide for Langerhans cell histiocytosis. Br J Haematol 1994; 86: 887-889.
18. Ogami A, Morimoto A, Hibi S, et al. Secondary acute promyelocytic leukemia following chemotherapy for non-Hodgkin's lymphoma in a child. J Pediatr Hematol Oncol 2004; 26: 427-430.
19. Imashuku S, Teramura T, Kuriyama K, et al. Risk of etoposide-related acute myeloid leukemia in the treatment of Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis. Int J Hematol 2002; 75: 174-177.
20. Rudd E, Göransdotter Ericson K, Zheng C, et al. Spectrum and clinical implications of syntaxin 11 gene mutations in familial haemophagocytic lymphohistiocytosis: Association with disease-free remissions and haematopoietic malignancies. J Med Genet 2006; 43: e14.