Usual physical activity and hip fracture in older men: An application of semiparametric methods to observational data

American Journal of Epidemiology

Volumn 173, Issue 5, 2011, Pages 578-586

  MacKey, Dawn C ^a,b   Hubbard, Alan E ^a   Cawthon, Peggy M ^b   Cauley, Jane A ^c   Cummings, Steven R ^b   Tager, Ira B ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b CALIFORNIA PACIFIC MEDICAL CENTER   (United States)

^c UNIVERSITY OF PITTSBURGH GRADUATE SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

aged; confounding factors (epidemiology); exercise; hip fractures; men; motor activity; prospective studies

Indexed keywords

CALCIUM;

AGE CLASS; BONE; CONFIDENCE INTERVAL; ELDERLY POPULATION; EPIDEMIOLOGY; OSTEOLOGY; SKELETON;

AGED; ANAMNESIS; ARTICLE; CALCIUM INTAKE; CLINICAL ASSESSMENT; CONFOUNDING VARIABLE; DAILY LIFE ACTIVITY; GRIP STRENGTH; HEALTH STATUS; HIP FRACTURE; HOUSEHOLD; HUMAN; MAJOR CLINICAL STUDY; MALE; PHYSICAL ACTIVITY; QUESTIONNAIRE; RANDOMIZATION; RISK ASSESSMENT; RISK FACTOR; STANDING; WALKING;

AGED; FOLLOW-UP STUDIES; HIP FRACTURES; HUMANS; INCIDENCE; MALE; MATHEMATICAL COMPUTING; MOTOR ACTIVITY; OSTEOPOROTIC FRACTURES; PROSPECTIVE STUDIES; QUESTIONNAIRES; RISK ASSESSMENT; RISK FACTORS; UNITED STATES;

UNITED STATES;

EID: 79952129832     PISSN: 00029262     EISSN: 14766256     Source Type: Journal    
DOI: 10.1093/aje/kwq405     Document Type: Article

References (45)

1. Bentler SE, Liu L, Obrizan M, et al. The aftermath of hip fracture: discharge placement, functional status change, and mortality. Am J Epidemiol. 2009;170(10):1290-1299.
2. Brauer CA, Coca-Perraillon M, Cutler DM, et al. Incidence and mortality of hip fractures in the United States. JAMA. 2009;302(14):1573-1579.
3. Center JR, Nguyen TV, Schneider D, et al. Mortality after all major types of osteoporotic fracture in men and women: an observational study. Lancet. 1999;353(9156):878-882. (Pubitemid 29126875)
4. Liu-Ambrose TY, Khan KM, Eng JJ, et al. Both resistance and agility training increase cortical bone density in 75-to 85-year-old women with low bone mass: a 6-month randomized controlled trial. J Clin Densitom. 2004;7(4):390-398. (Pubitemid 40115999)
5. Karinkanta S, Heinonen A, Sievänen H, et al. A multi-component exercise regimen to prevent functional decline and bone fragility in home-dwelling elderly women: randomized, controlled trial. Osteoporos Int. 2007;18(4):453-462. (Pubitemid 46354919)
6. Fiatarone MA, O'Neill EF, Ryan ND, et al. Exercise training and nutritional supplementation for physical frailty in very elderly people. N Engl J Med. 1994;330(25):1769-1775. (Pubitemid 24177611)
7. Lord SR, Ward JA, Williams P, et al. The effect of a 12-month exercise trial on balance, strength, and falls in older women: a randomized controlled trial. J Am Geriatr Soc. 1995;43(11):1198-1206.
8. Schlicht J, Camaione DN, Owen SV. Effect of intense strength training on standing balance, walking speed, and sit-to-stand performance in older adults. J Gerontol A Biol Sci Med Sci. 2001;56(5):M281-M286. (Pubitemid 32381805)
9. Wolf SL, Barnhart HX, Ellison GL, et al. The effect of Tai Chi Quan and computerized balance training on postural stability in older subjects. Phys Ther. 1997;77(4):371-381.
10. Liu-Ambrose T, Khan KM, Eng JJ, et al. Resistance and agility training reduce fall risk in women aged 75 to 85 with low bone mass: a 6-month randomized, controlled trial. J Am Geriatr Soc. 2004;52(5):657-665. (Pubitemid 38596481)
11. Lord SR, Castell S, Corcoran J, et al. The effect of group exercise on physical functioning and falls in frail older people living in retirement villages: a randomized, controlled trial. J Am Geriatr Soc. 2003;51(12):1685- 1692. (Pubitemid 37543353)
12. Province MA, Hadley EC, Hornbrook MC, et al. The effects of exercise on falls in elderly patients. A preplanned metaanalysis of the FICSIT Trials. Frailty and Injuries: Cooperative Studies of Intervention Techniques. JAMA. 1995;273(17):1341-1347.
13. Campbell AJ, Robertson MC, Gardner MM, et al. Randomised controlled trial of a general practice programme of home based exercise to prevent falls in elderly women. BMJ. 1997;315(7115):1065-1069. (Pubitemid 27458401)
14. Moayyeri A. The association between physical activity and osteoporotic fractures: a review of the evidence and implications for future research. Ann Epidemiol. 2008;18(11):827-835.
15. Feskanich D, Willett W, Colditz G. Walking and leisure-time activity and risk of hip fracture in postmenopausal women. JAMA. 2002;288(18):2300-2306. (Pubitemid 35291760)
16. Gregg EW, Cauley JA, Seeley DG, et al. Physical activity and osteoporotic fracture risk in older women. Study of Osteoporotic Fractures Research Group. Ann Intern Med. 1998;129(2):81-88. (Pubitemid 28337248)
17. Høidrup S, Sørensen TI, Strøger U, et al. Leisure-time physical activity levels and changes in relation to risk of hip fracture in men and women. Am J Epidemiol. 2001;154(1):60-68. (Pubitemid 32565687)
18. Blank JB, Cawthon PM, Carrion-Petersen ML, et al. Overview of recruitment for the Osteoporotic Fractures in Men Study (MrOS). Contemp Clin Trials. 2005;26(5):557-568. (Pubitemid 41242401)
19. Orwoll E, Blank JB, Barrett-Connor E, et al. Design and baseline characteristics of the Osteoporotic Fractures in Men (MrOS) Study-a large observational study of the determinants of fracture in older men. Contemp Clin Trials. 2005;26(5):569-585. (Pubitemid 41242402)
20. Washburn RA, Smith KW, Jette AM, et al. The Physical Activity Scale for the Elderly (PASE): development and evaluation. J Clin Epidemiol. 1993;46(2):153-162. (Pubitemid 23092124)
21. Block G, Woods M, Potosky A, et al. Validation of a selfadministered diet history questionnaire using multiple diet records. J Clin Epidemiol. 1990;43(12):1327-1335.
22. Cummings SR, Cawthon PM, Ensrud KE, et al. BMD and risk of hip and nonvertebral fractures in older men: a prospective study and comparison with older women. J Bone Miner Res. 2006;21(10):1550-1556. (Pubitemid 44484599)
23. Cawthon PM, Fullman RL, Marshall L, et al. Physical performance and risk of hip fractures in older men. J Bone Miner Res. 2008;23(7):1037-1044. (Pubitemid 351915725)
24. Neyman J. On the application of probability theory to agricultural experiments. Stat Sci. 1990;5(4):465-480.
25. Rubin DB. Bayesian inference for causal effects: the role of randomization. Ann Statist. 1978;6(1):34-58.
26. van der Laan MJ, Robins JM. Unified Methods for Censored Longitudinal Data and Causality. New York, NY: Springer-Verlag; 2003.
27. Cole SR, Hernán MA. Constructing inverse probability weights for marginal structural models. Am J Epidemiol. 2008;168(6):656-664.
28. Mortimer KM, Neugebauer R, van der Laan M, et al. An application of model-fitting procedures for marginal structural models. Am J Epidemiol. 2005;162(4):382-388. (Pubitemid 41389720)
29. Petersen ML, Wang Y, van der Laan MJ, et al. Assessing the effectiveness of antiretroviral adherence interventions. Using marginal structural models to replicate the findings of randomized controlled trials. J Acquir Immune Defic Syndr. 2006;43(suppl 1): S96-S103. (Pubitemid 44885647)
30. Robins JM, Hernán MA, Brumback B. Marginal structural models and causal inference in epidemiology. Epidemiology. 2000;11(5):550-560. (Pubitemid 30660034)
31. Sinisi SE, van der Laan MJ. Deletion/substitution/addition algorithm in learning with applications in genomics. Stat Appl Genet Mol Biol. 2004;3(1): article 18. (doi: 10.2202/1544-6115.1069).
32. van der Laan MJ, Gruber S. Collaborative double robust targeted maximum likelihood estimation. Int J Biostat. 2010;6(1): article 17. (doi: 10.2202/1557-4679. 1181).
33. van der Laan MJ, Rubin D. Targeted maximum likelihood learning. Int J Biostat. 2006;2(1): article 11. (doi: 10.2202/1557-4679.1043).
34. Kujala UM, Kaprio J, Kannus P, et al. Physical activity and osteoporotic hip fracture risk in men. Arch Intern Med. 2000;160(5):705-708. (Pubitemid 30140421)
35. Meyer HE, Tverdal A, Falch JA. Risk factors for hip fracture in middle-aged Norwegian women and men. Am J Epidemiol. 1993;137(11):1203-1211. (Pubitemid 23205895)
36. Mussolino ME, Looker AC, Madans JH, et al. Risk factors for hip fracture in white men: the NHANES I Epidemiologic Follow-up Study. J Bone Miner Res. 1998;13(6):918-924. (Pubitemid 28265269)
37. Grisso JA, Kelsey JL, O'Brien LA, et al. Risk factors for hip fracture in men. Hip Fracture Study Group. Am J Epidemiol. 1997;145(9):786-793. (Pubitemid 27188515)
38. Michaëlsson K, Olofsson H, Jensevik K, et al. Leisure physical activity and the risk of fracture in men. PLoS Med. 2007;4(6):e199. (doi: 10.1371/journal.pmed.0040199). (Pubitemid 46998626)
39. Paganini-Hill A, Chao A, Ross RK, et al. Exercise and other factors in the prevention of hip fracture: the Leisure World Study. Epidemiology. 1991;2(1):16-25.
40. Robling AG, Burr DB, Turner CH. Partitioning a daily mechanical stimulus into discrete loading bouts improves the osteogenic response to loading. J Bone Miner Res. 2000;15(8):1596-1602. (Pubitemid 30484530)
41. Robling AG, Burr DB, Turner CH. Recovery periods restore mechanosensitivity to dynamically loaded bone. J Exp Biol. 2001;204(pt 19):3389):3389-3399. (Pubitemid 34861350)
42. Cawthon PM, Ewing SK, McCulloch CE, et al. Loss of hip BMD in older men: the Osteoporotic Fractures in Men (MrOS) Study. J Bone Miner Res. 2009;24(10):1728-1735.
43. Cauley JA, Lacroix AZ, Wu L, et al. Serum 25-hydroxyvitamin D concentrations and risk for hip fractures. Ann Intern Med. 2008;149(4):242-250.
44. Looker AC, Mussolino ME. Serum 25-hydroxyvitamin D and hip fracture risk in older U. S. white adults. J Bone Miner Res. 2008;23(1):143-150.
45. Mackey DC, Hubbard A, Tager I, et al. Physical activity effects on hip fracture in older men [abstract]. Am J Epidemiol. 2009;169(suppl): S94.