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Volumn 13, Issue 2, 2011, Pages 97-106

Rufinamide for pediatric patients with Lennox-Gastaut syndrome: A comprehensive overview

Author keywords

[No Author keywords available]

Indexed keywords

CARBAMAZEPINE; CARBOXYLESTERASE; CGP 47292; CLOBAZAM; CLONAZEPAM; DRUG METABOLITE; ETHINYLESTRADIOL; FELBAMATE; LAMOTRIGINE; NORETHISTERONE; ORA PLUS; ORA SWEET; ORA SWEET SF; OXCARBAZEPINE; PHENOBARBITAL; PHENYTOIN; PLACEBO; PRIMIDONE; RUFINAMIDE; SODIUM CHANNEL; TOPIRAMATE; UNCLASSIFIED DRUG; VALPROIC ACID; VIGABATRIN;

EID: 79952126763     PISSN: 11745878     EISSN: 11792019     Source Type: Journal    
DOI: 10.2165/11586920-000000000-00000     Document Type: Review
Times cited : (28)

References (32)
  • 2
    • 77950641483 scopus 로고    scopus 로고
    • Medical management of Lennox-Gastaut syndrome
    • Michoulas A, Farrell K. Medical management of Lennox-Gastaut syndrome. CNS Drugs 2010; 24 (5): 363-74
    • (2010) CNS Drugs , vol.24 , Issue.5 , pp. 363-374
    • Michoulas, A.1    Farrell, K.2
  • 3
    • 1642498346 scopus 로고    scopus 로고
    • Lennox-Gastaut Syndrome (Childhood Epileptic Encephalopathy)
    • DOI 10.1097/00004691-200311000-00005
    • Markand ON. Lennox-Gastaut syndrome (childhood epileptic encephalopathy). J Clin Neurophysiol 2003; 20 (6): 426-41 (Pubitemid 38133970)
    • (2003) Journal of Clinical Neurophysiology , vol.20 , Issue.6 , pp. 426-441
    • Markand, O.N.1
  • 4
    • 0001539938 scopus 로고
    • Clinical correlates of the fast and the slow spike-wave electroencephalogram
    • Lennox WG, Davis JP. Clinical correlates of the fast and the slow spike-wave electroencephalogram. Pediatrics 1950; 5 (4): 626-44
    • (1950) Pediatrics , vol.5 , Issue.4 , pp. 626-644
    • Lennox, W.G.1    Davis, J.P.2
  • 5
    • 0017341238 scopus 로고
    • Treatment of generalized epilepsies of childhood and adolescence with sodium valproate ('Epilim')
    • Jeavons PM, Clark JE, Maheshwari MC. Treatment of generalized epilepsies of childhood and adolescence with sodium valproate ("epilim"). Dev Med Child Neurol 1977; 19 (1): 9-25 (Pubitemid 8036537)
    • (1977) Developmental Medicine and Child Neurology , vol.19 , Issue.1 , pp. 9-25
    • Jeavons, P.M.1    Clark, J.E.2    Maheshwari, M.C.3
  • 6
    • 68249089775 scopus 로고    scopus 로고
    • Woodcliff Lake (NJ): Eisai Inc
    • Banzel [package insert]. Woodcliff Lake (NJ): Eisai Inc, 2008
    • (2008) Banzel [Package Insert]
  • 7
    • 33747038871 scopus 로고    scopus 로고
    • The influence of rufinamide on sodium currents and action potential firing in rodent neurons
    • McLean MJ, Schmutz M, Pozza M, et al. The influence of rufinamide on sodium currents and action potential firing in rodent neurons. Epilepsia 2005; 46 Suppl. 8: 296
    • (2005) Epilepsia , vol.46 , Issue.SUPPL. 8 , pp. 296
    • McLean, M.J.1    Schmutz, M.2    Pozza, M.3
  • 8
    • 0033061573 scopus 로고    scopus 로고
    • Progress report on new antiepileptic drugs: A summary of The Fourth Eilat Conference (EILAT IV)
    • DOI 10.1016/S0920-1211(98)00108-9, PII S0920121198001089
    • Bialer M, Johannesen SI, Kupferberg HJ, et al. Progress report on new antiepileptic drugs: a summary of the fourth Eilat conference (EILAT IV). Epilepsy Res 1999; 34 (1): 1-41 (Pubitemid 29130316)
    • (1999) Epilepsy Research , vol.34 , Issue.1 , pp. 1-41
    • Bialer, M.1    Johannessen, S.I.2    Kupferberg, H.J.3    Levy, R.H.4    Loiseau, P.5    Perucca, E.6
  • 9
    • 45749116975 scopus 로고    scopus 로고
    • Rufinamide: Clinical pharmacokinetics and concentration-response relationships in patients with epilepsy
    • DOI 10.1111/j.1528-1167.2008.01665.x
    • Perucca E, Cloyd J, Critchley D, et al. Rufinamide: clinical pharmacokinetics and concentration-response relationships in patients with epilepsy. Epilepsia 2008; 49 (7): 1123-41 (Pubitemid 351991401)
    • (2008) Epilepsia , vol.49 , Issue.7 , pp. 1123-1141
    • Perucca, E.1    Cloyd, J.2    Critchley, D.3    Fuseau, E.4
  • 10
    • 47249119666 scopus 로고    scopus 로고
    • The anticonvulsant profile of rufinamide (CGP 33101) in rodent seizure models
    • DOI 10.1111/j.1528-1167.2008.01552.x
    • White HS, Franklin MR, Kupferberg HJ, et al. The anticonvulsant profile of rufinamide (CGP33101) in rodent seizuremodels. Epilepsia 2008; 49 (7): 1213-20 (Pubitemid 351991388)
    • (2008) Epilepsia , vol.49 , Issue.7 , pp. 1213-1220
    • White, H.S.1    Franklin, M.R.2    Kupferberg, H.J.3    Schmutz, M.4    Stables, J.P.5    Wolf, H.H.6
  • 11
    • 0034663006 scopus 로고    scopus 로고
    • Modulation of absence seizures by the GABA(A) receptor: A critical role for metabotropic glutamate receptor 4 (mGluR4)
    • Snead III OC, Banerjee PK, Burnham M, et al. Modulation of absence seizures by the GABA(A) receptor: a critical role for metabotropic glutamate receptor 4 (mGluR4). J Neurosci 2000; 20 (16): 6218-24 (Pubitemid 30658415)
    • (2000) Journal of Neuroscience , vol.20 , Issue.16 , pp. 6218-6224
    • Snead III, O.C.1    Banerjee, P.K.2    Burnham, M.3    Hampson, D.4
  • 12
    • 44949184519 scopus 로고    scopus 로고
    • Rufinamide for generalized seizures associated with Lennox-Gastaut syndrome
    • Glauser T, Kluger G, Sachdeo R, et al. Rufinamide for generalized seizures associated with Lennox-Gastaut syndrome. Neurology 2008; 70 (21): 1950-8
    • (2008) Neurology , vol.70 , Issue.21 , pp. 1950-1958
    • Glauser, T.1    Kluger, G.2    Sachdeo, R.3
  • 13
    • 0000489497 scopus 로고    scopus 로고
    • Pharmacokinetics and safety of adjunctive rufinamide therapy in pediatric patients with epilepsy
    • Sachdeo RC, Rovenfeld WE, Choi L. Pharmacokinetics and safety of adjunctive rufinamide therapy in pediatric patients with epilepsy. Epilepsia 1998; 39 (6): 166-7
    • (1998) Epilepsia , vol.39 , Issue.6 , pp. 166-167
    • Sachdeo, R.C.1    Rovenfeld, W.E.2    Choi, L.3
  • 14
    • 76049084221 scopus 로고    scopus 로고
    • A 24-week multicenter randomized doubleblind parallel-group dose-ranging study of rufinamide in adults and adolescents with inadequately controlled partial seizures
    • Elger CE, Stefan H, Mann A, et al.A24-week multicenter randomized, doubleblind, parallel-group, dose-ranging study of rufinamide in adults and adolescents with inadequately controlled partial seizures. Epilepsy Res 2010; 88 (2-3): 255-63
    • (2010) Epilepsy Res , vol.88 , Issue.2-3 , pp. 255-263
    • Elger, C.E.1    Stefan, H.2    Mann, A.3
  • 15
    • 0006757668 scopus 로고    scopus 로고
    • A pharmacokinetic evaluation of rufinamide in elderly and younger subjects
    • Chang SW, Choi L, Karopheyk MA. A pharmacokinetic evaluation of rufinamide in elderly and younger subjects. Epilepsia 1998; 39 Suppl. 6: S59
    • (1998) Epilepsia , vol.39 , Issue.SUPPL. 6
    • Chang, S.W.1    Choi, L.2    Karopheyk, M.A.3
  • 16
  • 17
    • 77949266502 scopus 로고    scopus 로고
    • Supporting the recommended paediatric dosing regimen for rufinamide in Lennox-Gastaut syndrome using clinical trial simulation
    • Marchand M, Fuseau E, Critchley DJ. Supporting the recommended paediatric dosing regimen for rufinamide in Lennox-Gastaut syndrome using clinical trial simulation. J Pharmacokinet Pharmacodyn 2010; 37 (1): 99-118
    • (2010) J Pharmacokinet Pharmacodyn , vol.37 , Issue.1 , pp. 99-118
    • Marchand, M.1    Fuseau, E.2    Critchley, D.J.3
  • 18
    • 33748519527 scopus 로고    scopus 로고
    • Rufinamide
    • DOI 10.2165/00023210-200620090-00007
    • Deeks ED, Scott LJ. Rufinamide. CNS Drugs 2006; 20 (9): 751-60 (Pubitemid 44373706)
    • (2006) CNS Drugs , vol.20 , Issue.9 , pp. 751-760
    • Deeks, E.D.1    Scott, L.J.2
  • 19
    • 0029566317 scopus 로고
    • Intra- and inter-subject variabilities of CGP 33101 after replicate single oral doses of two 200-mg tablets and 400-mg suspension
    • DOI 10.1023/A:1016275402723
    • Cheung WK, Kianifard F, Wong A, et al. Intra-and inter-subject variabilities of CGP 33101 after replicate single oral doses of two 200-mg tablets and 400 mg suspension. Pharm Res 1995; 12 (12): 1878-82 (Pubitemid 26032294)
    • (1995) Pharmaceutical Research , vol.12 , Issue.12 , pp. 1878-1882
    • Cheung, W.K.1    Kianifard, F.2    Wong, A.3    Mathieu, J.4    Cook, T.5    John, V.6    Redalieu, E.7    Chan, K.8
  • 20
    • 0031959729 scopus 로고    scopus 로고
    • The influence of food on the disposition of the antiepileptic rufinamide in healthy volunteers
    • DOI 10.10 02/(SICI)10 99-081X(199 805)19:4<259 ::AID-BD D98>3.0.CO;2-V
    • Cardot JM, Lecaillon JB, Czendlik C, et al. The influence of food on the disposition of the antiepileptic rufinamide in healthy volunteers. Biopharm Drug Dispos 1998; 19: 259-62 (Pubitemid 28218421)
    • (1998) Biopharmaceutics and Drug Disposition , vol.19 , Issue.4 , pp. 259-262
    • Cardot, J.-M.1    Lecaillon, J.-B.2    Czendlik, C.3    Godbillon A, J.4
  • 21
    • 0035150482 scopus 로고    scopus 로고
    • Rufinamide: A double-blind, placebo-controlled proof of principle trial in patients with epilepsy
    • DOI 10.1016/S0920-1211(00)00185-6, PII S0920121100001856
    • Palhagen S, Canger R, Henriksen O, et al. Rufinamide: a double-blind, placebocontrolled proof of principle trial in patients with epilepsy. Epilepsy Res 2001; 43 (2): 115-24 (Pubitemid 32115522)
    • (2001) Epilepsy Research , vol.43 , Issue.2 , pp. 115-124
    • Palhagen, S.1    Canger, R.2    Henriksen, O.3    Van Parys, J.A.4    Riviere, M.-E.5    Karolchyk, M.A.6
  • 22
    • 68749111361 scopus 로고    scopus 로고
    • Treatment of Lennox-Gastaut syndrome (LGS)
    • Ferrie CD, Patel A. Treatment of Lennox-Gastaut syndrome (LGS). Eur J Paediatr Neurol 2009; 13 (6): 493-504
    • (2009) Eur J Paediatr Neurol , vol.13 , Issue.6 , pp. 493-504
    • Ferrie, C.D.1    Patel, A.2
  • 23
    • 85129694326 scopus 로고    scopus 로고
    • Rufinamide: A novel broad-spectrum antiepileptic drug
    • Wheless JW, Vazquez B. Rufinamide: a novel broad-spectrum antiepileptic drug. Epilepsy Curr 2010; 10 (1): 1-6
    • (2010) Epilepsy Curr , vol.10 , Issue.1 , pp. 1-6
    • Wheless, J.W.1    Vazquez, B.2
  • 24
    • 33846185983 scopus 로고    scopus 로고
    • Rufinamide
    • DOI 10.1016/j.nurt.2006.11.006, PII S1933721306001851, New Antiepileptic Drugs: Discovery, Development, and Update
    • Arroyo S. Rufinamide. Neurotherapeutics 2007; 4 (1): 155-62 (Pubitemid 46107325)
    • (2007) Neurotherapeutics , vol.4 , Issue.1 , pp. 155-162
    • Arroyo, S.1
  • 25
    • 77955298453 scopus 로고    scopus 로고
    • Adjunctive rufinamide in Lennox-Gastaut syndrome: A long-term open-label extension study
    • Kluger G, Glauser T, Krauss G, et al. Adjunctive rufinamide in Lennox-Gastaut syndrome: a long-term, open-label extension study. Acta Neurol Scand 2010; 122 (3): 202-8
    • (2010) Acta Neurol Scand , vol.122 , Issue.3 , pp. 202-208
    • Kluger, G.1    Glauser, T.2    Krauss, G.3
  • 26
    • 77952240784 scopus 로고    scopus 로고
    • First European long-term experience with the orphan drug rufinamide in childhood-onset refractory epilepsy
    • Kluger G, Haberlandt E, Kurlemann G, et al. First European long-term experience with the orphan drug rufinamide in childhood-onset refractory epilepsy. Epilepsy Behav 2010; 17 (4): 546-8
    • (2010) Epilepsy Behav , vol.17 , Issue.4 , pp. 546-548
    • Kluger, G.1    Haberlandt, E.2    Kurlemann, G.3
  • 27
    • 63249107131 scopus 로고    scopus 로고
    • Effectiveness and tolerability of rufinamide in children and adults with refractory epilepsy; First European experience
    • Kluger G, Kurdlemann G, Haberlandt E, et al. Effectiveness and tolerability of rufinamide in children and adults with refractory epilepsy; first European experience. Epilepsy Behav 2009; 14 (3): 491-5
    • (2009) Epilepsy Behav , vol.14 , Issue.3 , pp. 491-495
    • Kluger, G.1    Kurdlemann, G.2    Haberlandt, E.3
  • 28
    • 68149096743 scopus 로고    scopus 로고
    • Rufinamide for the adjunctive treatment of partial seizures in adults and adolescents: A randomized placebocontrolled trial
    • Brodie MJ, Rosenfeld WE, Vazquez B, et al. Rufinamide for the adjunctive treatment of partial seizures in adults and adolescents: a randomized placebocontrolled trial. Epilepsia 2009; 50 (8): 1899-909
    • (2009) Epilepsia , vol.50 , Issue.8 , pp. 1899-1909
    • Brodie, M.J.1    Rosenfeld, W.E.2    Vazquez, B.3
  • 29
    • 79952139953 scopus 로고    scopus 로고
    • Adopting an orphan drug: Rufinamide for Lennox-Gastaut syndrome
    • Herman ST. Adopting an orphan drug: rufinamide for Lennox-Gastaut syndrome. Epilepsy Curr 2009; 9 (3): 72-4
    • (2009) Epilepsy Curr , vol.9 , Issue.3 , pp. 72-74
    • Herman, S.T.1
  • 30
    • 75149122341 scopus 로고    scopus 로고
    • Safety and tolerability of rufinamide in children with epilepsy: A pooled analysis of 7 clinical studies
    • Wheless JW, Conry J, Krauss G, et al. Safety and tolerability of rufinamide in children with epilepsy: a pooled analysis of 7 clinical studies. J Child Neurol 2009; 24 (12): 1520-5
    • (2009) J Child Neurol , vol.24 , Issue.12 , pp. 1520-1525
    • Wheless, J.W.1    Conry, J.2    Krauss, G.3
  • 31
    • 77749314406 scopus 로고    scopus 로고
    • Stability of extemporaneously prepared rufinamide oral suspensions
    • Hutchinson DJ, Liou Y, Best R, et al. Stability of extemporaneously prepared rufinamide oral suspensions. Ann Pharmacother 2010; 44 (3): 462-5
    • (2010) Ann Pharmacother , vol.44 , Issue.3 , pp. 462-465
    • Hutchinson, D.J.1    Liou, Y.2    Best, R.3
  • 32
    • 22244452355 scopus 로고    scopus 로고
    • Rufinamide: CGP 33101, E 2080, RUF 331, Xilep
    • Rufinamide: CGP 33101, E 2080, RUF 331, Xilep. Drugs R D 2005; 6 (4): 249-52
    • (2005) Drugs R D , vol.6 , Issue.4 , pp. 249-252


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