Epstein-Barr virus, cytomegalovirus, and infectious mononucleosis

Adolescent Medicine: State of the Art Reviews

Volumn 21, Issue 2, 2010, Pages 251-264

  Bravender, Terrill ^a  

^a THE OHIO STATE UNIVERSITY COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADOLESCENT; CYTOMEGALOVIRUS INFECTION; EPSTEIN BARR VIRUS INFECTION; HUMAN; INFECTIOUS MONONUCLEOSIS; MEDICINE; REVIEW; VIROLOGY;

ADOLESCENT; ADOLESCENT MEDICINE; CYTOMEGALOVIRUS INFECTIONS; EPSTEIN-BARR VIRUS INFECTIONS; HUMANS; INFECTIOUS MONONUCLEOSIS;

EID: 79952113289     PISSN: 19344287     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (86)

1. Evans AS. The history of infectious mononucleosis. Am J Med Sci. 1974;267(3):189-195
2. Sprunt TP, Evans FA. Mononucleosis leukocytosis in reaction to acute infections (infectious mononucleosis). Johns Hopkins Hospital Bulletin. 1920;31:410
3. Davidsohn I. Serologic diagnosis of infectious mononucleosis. JAMA. 1937;108:289-295
4. Paul JR, Bumell WW. The presence of heterophile antibodies in infectious mononucleosis. Am J Med Sci. 1932;183:90-104
5. Basson V, Sharp AA. Monospot: a differential slide test for infectious mononucleosis. J Clin Pathol. 1969;22:324-325
6. Epstein MA, Achong BG, Barr YM. Virus particles in cultured lymphoblasts from Burkitt's lymphoma. Lancet. 1964;l(7335):702-703
7. Henle G, Henle W, Diehl V. Relation of Burkitt's tumor-associated herpes-ytpe virus to infectious mononucleosis. Proc Natl Acad Sci USA. 1968;59(1):94-101
8. Hurt C, Tammaro D. Diagnostic evaluation of mononucleosis-like illnesses. Am J Med. 2007; 120(10);el-e8
9. BravenderT, Walter EB. Infectious respiratory illnesses. In: Neinstein LS, Gordon CM, Katzman DK, Rosen DS, Woods ER, eds. Adolescent Healthcare: A Practical Guide. 5th ed. Philadelphia, PA: Lippincott Williams & Wilkins; 2008:413-426
10. Thorley-Lawson DA, Gross A. Persistence of the Epstein-Barr virus and the origins of associated lymphomas. N Engl J Med. 2004;350(13);1328-1337 (Pubitemid 38375368)
11. Miyashita EM, Yang B, Lam KM, Crawford DH, Thorley-Lawson DA. A novel form of Epstein-Barr virus latency in normal B cells in vivo. Cell. 1995;80(4):593-601
12. Hadinoto V, Shapiro M, Sun CC, Thorley-Lawson DA. The dynamics of EBV shedding implicate a central role for epithelial cells in amplifying viral output. Plos Pathogens. 2009; 5(7):el000496
13. Rowe M. Cell transformation induced by Epstein-Barr virus-living dangerously. Sem Cancer Biol. 2001;11(6):403-405 (Pubitemid 33105018)
14. Fleisher G, Henle G, Lennette ET, Biggar RJ. Primary infection with Epstein-Barr virus in infants in the United States: clinical and serologic observations. J Infect Dis. 1979;139:553-558 (Pubitemid 9158545)
15. Pereira MS, Blake JM, Macrae AD. EB virus antibody at different ages. BMJ. 1969;4:526-527
16. Nye FJ. Social class and infectious mononucleosis. J Hygiene. 1973;71:145-149
17. Johannsen EC, Kaye KM. Epstein-Barr virus (infectious mononucleosis, Epstein-Barr virus-associated malignant diseases, and other diseases. In: Mandell GL, Bennett JE, Dolin R, eds. Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases. 7th ed. Philadelphia, PA: Churchill, Livingston; 2009:1989-2010
18. Sumaya CV, Ench Y. Epstein-Barr virus infections in families: the role of children with infectious mononucleosis. J Infect Dis. 1986;154(5):842-850 (Pubitemid 17181611)
19. Henke CE, Kurland LT, Elveback LR. Infectious mononucleosis in Rochester, Minnesota, 1950 through 1969. Am J Epidemiol. 1973;98(6):483-490
20. Sitki-Green DL, Edwards RH, Covington MM, Raab-Traub N. Biology of Epstein-Barr virus during infectious mononucleosis. J Infect Dis. 2004;189(3):483-492 (Pubitemid 38210585)
21. Gerber MA, Shapiro ED, Ryan RW, Bell GL. Evaluations of enzyme-linked immunosorbent assay procedure for determining specific Epstein-Barr virus serology and of rapid test kits for diagnosis for infectious mononucleosis. J Clin Microbiol. 1996;34(12):3240-3241 (Pubitemid 26389394)
22. Bell AT, Fortune B. What test is the best for diagnosing infectious mononucleosis? J Fam Pract. 2006;55(9);799-802
23. Linderholm M, Bowman J, Juto P, Linde A. comparative evaluation of nine kits for rapid diagnosis of infectious mononucleosis and Epstein-Barr virus-specific serology. J Clin Microbiol. 1994;32:259-307
24. Sumaya CV, Ench Y. Epstein-Barr virus infectious mononucleosis in children. II. Heterophil antiboy and viral-specific responses. Pediatrics. 1985;75:1011-1019 (Pubitemid 15036513)
25. Fleisher GR, Collins M, Fager S. Limitations of available tests for diagnosis of infectious mononucleosis. J Clin Microbiol. 1983;17(4):619-624 (Pubitemid 13160865)
26. Henle W, Henle GE, Horwitz CA. Epstein-Barr virus specific diagnostic tests in infectious mononucleosis. Human Pathol. 1974;5:551-565
27. Hoagland RJ. The clinical manifestations of infectious mononucleosis: a report of two hundred cases. Am J Med Sei. 1960;240:55-63
28. Brigden ML, Au S, Thompson S, Brigden S, Doyle P, Tsaparas Y. Infectious mononucleosis in an outpatient population: diagnostic utility of 2 automated hematology analyzers and the sensitivity and specificity of Hoagland's criteria in heterophile-positive patients. Arch Pathol Lab Med. 1999;123(10):875-881 (Pubitemid 29480444)
29. Horwitz CA, Moulds J, Henle W, et al. Cold agglutinins in infectious mononucleosis and heterophil-antibody-negative mononucleosis-like syndromes. Blood. 1977;50(2): 195-202 (Pubitemid 8140392)
30. Place E, Wenzel JE, Arumugam R, Belani K, Messinger Y. Successful plasmapheresis for extreme hyperbilirubinemia caused by acute Epstein-Barr virus. J Pediatr Hematol Oncol. 2007;29(5);323-326 (Pubitemid 46707514)
31. Grotto I, Mimouni D, Huerta M, et al. Clinical and laboratory presentation of EBV positive infectious mononucleosis in young adults. Epidemiol Infect. 2003;131(1);683-689 (Pubitemid 37062890)
32. Maki DG, Reich RM. infectious mononucleosis in the athlete. Diagnosis, complications, and management Am J Sports Med. 1982;10:62-73
33. Rutkow IM. Rupture of the spleen in infectious mononucleosis: a critical review. Arch Surg. 1978;113(6):718-720 (Pubitemid 8376037)
34. Smith EB, Custer RP. Rupture of the spleen in infectious mononucleosis: a clinicopathologic report of seven cases. Blood. 1946;1:317-333
35. Putukian M, O'Connor FG, Strieker PR, et al. Mononucleosis and athletic participation: an evidence-based subject review. Clin J Sports Med. 2008;18(4):309-315
36. Spielmann AL, DeLong DM, Kliewer MA. Sonographic evaluation of spleen size in tall healthy athletes. Am J Roentgenol. 2005;184:45-49 (Pubitemid 40040903)
37. Hosey RG, Mattacola CG, Kriss V, Armsey T, Quarles JD, Jagger J. Ultrasound assessment of spleen size in collegiate athletes. Br J Sports Med. 2006;40(3);251-254 (Pubitemid 43384744)
38. Chan SC, Dawes PJ. The management of severe infectious mononucleosis tonsillitis and upper airway obstruction. J Laryngol Otol. 2001,115(12):973-977 (Pubitemid 33152246)
39. Collins M, Fleisher G, Fager SS. Incidence of beta hemolytic streptococcal pharyngitis in adolescents with infectious mononucleosis. J Adolesc Health Care. 1984;5(2):96-100 (Pubitemid 14133359)
40. Leung AK, Rafaat M. Eruption associated with amoxicillin in a patient with infectious mononucleosis. Int J Dermatol. 2003;42(7);553-555 (Pubitemid 36869150)
41. Pauzek ME. Making a rash diagnosis: amoxicillin therapy in infectious mononucleosis. Indiana Med J. 1990;83:330-331
42. Renn CN, Straff W, Dorfmuller A, Al-Masaoudi T, Merk HF, Sachs B. Amoxicillin-induced exanthema in young adults with infectious mononucleosis: demonstration of drug-specific lymphocyte reactivity. Br J Dermatol. 2002;147(6): 1166-1170 (Pubitemid 36963023)
43. Connelly KP, DeWitt LD. Neurologic complications of infectious mononucleosis. Pediatr Neurol. 1994;10(3):181-184 (Pubitemid 24158898)
44. Doja A, Bitnun A, Ford Jones EL, et al. Pediatric Epstein-Barr virus-associated encephalitis: 10-year review. J Child Neurol. 2006;21(5);384-391 (Pubitemid 44057056)
45. Liaw SB, Shen EY. Alice in Wonderland syndrome as a presenting symptom of EBV infection. Pediatr Neurol. 1991;7(6):464-466
46. Halvorsen JA, Brevig T, Aas T, Skar AG, Slevolden EM, Moi H. Genital ulcers as initial manifestation of Epstein-Barr virus infection: two new cases and a review of the literature. Acta Dermato-Venereologica. 2006;86(5);439-442 (Pubitemid 44450102)
47. Harley JB, Harley ITW, Guthridge JM, James JA. The curiously suspicious: a role for Epstein-Barr virus in lupus. Lupus. 2006; 15(11);768-777
48. Pohl D. Epstein-Barr virus and multiple sclerosis. J Neurol Sci. 2009;286(l-2):62-64
49. Rea TD, Russo JE, Katon W, Ashley RL, Buchwald DS. Prospective study of the natural history of infectious mononucleosis caused by Epstein-Barr virus. J Am Board Fam Pract. 2001;14(4); 234-242
50. White PD, Thomas JM, Amess J, et al. Incidence, risk and prognosis of acute and chronic fatigue syndromes and psychiatric disorders after glandular fever. Br J Psychiatry. 1998;173:475-481 (Pubitemid 28557128)
51. Fleisher G, Schwartz J, Lennette E. Primary Epstein-Barr virus infection in association with Reye syndrome. J Pediatrics. 1980;97(6):935-937 (Pubitemid 11209373)
52. Tynell E, Aurelius E, Brandell A, et al. Acyclovir and prednisolone treatment of acute infectious mononucleosis: a multicenter, double-blind, placebo-controlled study. J Infect Dis. 1996; 174(2): 324-331 (Pubitemid 26251418)
53. Thompson SK, Doerr TD, Hengerer AS. Infectious mononucleosis and corticosteroids: management practices and outcomes. Arch Otolaryngol Head Neck Surg. 2005;131:900-904 (Pubitemid 41464483)
54. Sokal EM, Hoppenbrouwers K, Vandermeulen C, et al. Recombinant gp350 vaccine for infectious mononucleosis: a phase 2, randomized, double-bind, placeb-controlled trial to evaluate the safety, immunogenicity, and efficacy of an Epstein-Barr virus vaccine in healthy young adults. J Infect Dis. 2007;196(12): 1749-1753 (Pubitemid 351411934)
55. Cohen JI. Epstein-Barr virus infection. N Engl J Med. 2000;343(7):481-492 (Pubitemid 30646489)
56. Strauss SE. The chronic mononucleosis syndrome. J Infect Dis. 1988;157(3):405-412
57. Marshall GS. Report of a workshop on the epidemiology, natural history, and pathogenesis of chronic fatigue syndrome in adolescents. J Pediatrics. 1999;134(4):395-405 (Pubitemid 30180619)
58. Young LS, Rickinson AB. Epstein-Barr virus: 40 years on. Nature Rev Cancer. 2004;4:757-768 (Pubitemid 39331148)
59. Hsu JL, Glaser SL. Epstein-Barr virus-associated malignancies: epidemiologic patterns and etiologic implications. Crit Rev Oncol Hematol. 2000;34:27-53 (Pubitemid 30227315)
60. Carbone A, Gloghini A, Dotti G. EBV-associated lymphoproliferative disroders: classification and treatment. Oncologist. 2008;13(5):577-585 (Pubitemid 351872874)
61. Grierson H, Purtilo DT. Epstein-Barr virus infections in males with the X-linked lymphoproliferative syndrome. Ann Intern Med. 1987;106:538-545 (Pubitemid 17095038)
62. Kitazawa Y, Saito F, Nomura S, Ishii K, Kadota E. A case of hemophagocytic lymphohistio-cytosis after the primary Epstein-Barr virus infection. Clin Appl Thromb Hemost. 2007;13(3); 323-328 (Pubitemid 47000560)
63. Smith MG. Propagation in tissue cultures of a cytopathogenic virus from human salivary gland virus (SGV) disease. Proc Soc Exp Biol Med. 1956;92(2):424-430
64. Klemola E, Kaarianen L. Cytomegalovirus as a possible cause of a disease resembling infectious mononucleosis. Br Med J. 1965;2(5470):1099-1102
65. Kaarianen L, Klemola E, Paloheimo J. Rise of cytomegalovirus antibodies in an infectious-mononucleosis-like syndrome after transfusion. Br Med J. 1966; 1 (5498): 1270-1272
66. Adler SP, Marshall B. Cytomegalovirus infections. Pediatr Rev. 2007;28(3):92-100 (Pubitemid 46495837)
67. Drew WL. Cytomegalovirus infection in patients with AIDS. Clin Infect Dis. 1992;14(2):608-615
68. Beersma MF, Bijlmakers MJ, Ploegh HL. Human cytomegalovirus down-regulates HLA class I expression by reducing the stability of class I H chains. J Immunol. 1993;151(9): 4455-4464 (Pubitemid 23318498)
69. Crumpacker CS, Zhang JL. Cytomegalovirus. In: Mandell GL, Bennett JE, Dolin R, eds. Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases. 7th ed. Philadelphia, PA: Churchill, Livingston; 2009:1971-1987
70. Ross SA, Arora N, Novak Z, Fowler KB, Britt WJ, Boppana SB. Cytomegalovirus reinfections in healthy seroimmune women. J Infect Dis. 2010;201(3);386-389
71. Spector DH, Spector SA. The oncogenic potential of human cytomegalovirus. Prog Med Virol. 1984;29:45-89
72. Bale JF Jr, Zimmerman B, Dawson JD, Souza IE, Petheram SJ, Murph JR. Cytomegalovirus transmission in child care homes. Arch Pediatr Adolesc Med. 1999;153(1):75-79 (Pubitemid 29039364)
73. Murph JR, Bale JF Jr, Murray JC, Stinski MF, Perlman S. Cytomegalovirus transmission in a Midwest day care center: possible relationship to child care practices. J Pediatr. 1986;109(1): 35-39 (Pubitemid 16099838)
74. Murph JR, Baron JC, Brown CK, Ebelhack CL, Bale JF Jr. The occupational risk of cytomegalovirus infection among day-care providers. JAMA. 1991;265(5):603-608
75. Klemola E, Von Essen R, Henle G, Henle W. Infectious-mononucleosis-like disease with negative heterophil agglutination test. Clinical features in relation to Epstein-Barr virus and cytomegalovirus antibodies. J Infect Dis. 1970;121(6):608-614
76. Taylor GH. Cytomegalovirus. Am Fam Physician. 2003;67(3);519-524
77. Jordan MC, Rousseau W, Stewart JA, Noble GR, Chin TD. Spontaneous cytomegalovirus mononucleosis. Clinical and laboratory observations in nine cases. Ann Intern Med. 1973;79(2): 153-160
78. Wreghitt TG, Teare EL, Sule O, Devi R, Rice P. Cytomegalovirus infection in immunocompetent patients. Clin Infect Dis. 2003;37(12);1603-1606 (Pubitemid 37549944)
79. Just-Nubling G, Korn S, Ludwig B, Stephan C, Doerr HW, Preiser W. Primary cytomegalovirus infection in an outpatient setting-laboratory markers and clinical aspects. Infection. 2003;31(5): 318-323 (Pubitemid 37260366)
80. Springer KL, Weinberg A. Cytomegalovirus infection in the era of HAART: fewer reactivations and more immunity. J Antimicrob Chemother. 2004;54(3);582-586 (Pubitemid 39263897)
81. Fisher RA. Cytomegalovirus infection and disease in the new era of immunosuppression following solid organ transplantation. Transplant Infect Dis. 2009;11(3);195-202
82. Eddleston M, Peacock S, Juniper M, Warrell DA. Severe cytomegalovirus infection in immunocompetent patients. Clin Infect Dis. 1997;24(1):52-56 (Pubitemid 27023672)
83. Arvin AM, Fast P, Myers M, Plotkin S, Rabinovich R. Vaccine development to prevent cytomegalovirus disease: report from the National Vaccine Advisory Committee. Clin Infect Dis. 2004;39(2);233-239 (Pubitemid 38971495)
84. Fowler KB, Stagno S, Pass RF, Britt WJ, Boll TJ, Alford CA. The outcome of congenital cytomegalovirus infection in relation to maternal antibody status. N Engl J Med. 1992;326(10): 663-667
85. Pass RF, Zhang C, Evans A, et al. Vaccine prevention of maternal cytomegalovirus infection. N Engl J Med. 2009;360(12);1191-1199
86. Griffiths PD. CMV vaccine trial endpoints. J Clin Virol. 2009;46(Suppl 4):S64-S67