The 752delG26 mutation in the RFXANK gene associated with major histocompatibility complex class II deficiency: Evidence for a founder effect in the Moroccan population

European Journal of Pediatrics

Volumn 169, Issue 9, 2010, Pages 1069-1074

  Naamane, Hamid ^a   El Maataoui, Ouafaa ^b   Ailal, Fatima ^b   Barakat, Abdelhamid ^a   Bennani, Siham ^a   Najib, Jilali ^b   Hassar, Mohammed ^a   Saile, Rachid ^c   Bousfiha, Ahmed Aziz ^b  

^a Institut Pasteur du Maroc   (Morocco)

^b IBN ROCHD UNIVERSITY HOSPITAL   (Morocco)

^c HASSAN II UNIVERSITY   (Morocco)

Author keywords

Founder effect; MHC class ii immunodeficiency; Molecular diagnosis; RFXANK gene

Indexed keywords

DNA; HLA ANTIGEN CLASS 2; HLA DR ANTIGEN; IMMUNOGLOBULIN; RFXANK PROTEIN, HUMAN; TRANSCRIPTION FACTOR;

ANTIGEN PRESENTATION; ARTICLE; BLOOD; CD4 LYMPHOCYTE COUNT; CHILD; CYTOLOGY; ETHNOLOGY; FEMALE; FOUNDER EFFECT; GENE DELETION; GENETICS; HUMAN; IMMUNOLOGY; INFANT; LYMPHOCYTE; MALE; MOLECULAR GENETICS; MONONUCLEAR CELL; MOROCCO; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRESCHOOL CHILD; SEVERE COMBINED IMMUNODEFICIENCY;

ANTIGEN PRESENTATION; BASE SEQUENCE; CD4 LYMPHOCYTE COUNT; CHILD; CHILD, PRESCHOOL; DNA; FEMALE; FOUNDER EFFECT; GENE DELETION; HISTOCOMPATIBILITY ANTIGENS CLASS II; HLA-DR ANTIGENS; HUMANS; IMMUNOGLOBULINS; INFANT; LEUKOCYTES, MONONUCLEAR; LYMPHOCYTES; MALE; MOLECULAR SEQUENCE DATA; MOROCCO; POLYMERASE CHAIN REACTION; SEVERE COMBINED IMMUNODEFICIENCY; TRANSCRIPTION FACTORS;

EID: 79952111520     PISSN: 03406199     EISSN: 14321076     Source Type: Journal    
DOI: 10.1007/s00431-010-1179-6     Document Type: Article

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