Pharmacokinetics in rats and efficacy in murine ovarian cancer model for solid lipid nanoparticles loading docetaxel

Journal of Nanoscience and Nanotechnology

Volumn 10, Issue 11, 2010, Pages 7541-7544

  Zhang, Pengcheng ^a   Chen, Lingli ^a   Zhang, Zhiwen ^a   Lin, Liping ^a   Li, Yaping ^a  

^a SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

Anti tumor efficacy; Docetaxel; Ovarian carcinoma; Pharmacokinetics; Solid lipid nanoparticles

Indexed keywords

ACUTE TOXICITY; ANTI-TUMOR ACTIVITIES; ANTI-TUMOR EFFICACY; BIODISTRIBUTIONS; CIRCULATION SYSTEMS; DOCETAXEL; ENCAPSULATION EFFICIENCY; ENDOTHELIAL SYSTEMS; IN-VIVO; LOADING CAPACITIES; LOW TOXICITY; MAXIMUM TOLERATED DOSE; MEAN RESIDENCE TIME; OVARIAN CANCERS; OVARIAN CARCINOMA; RELEASE BEHAVIORS; SIDE EFFECT; SOLID LIPID NANOPARTICLES; TAXOTERE;

DISEASES; ENCAPSULATION; NANOPARTICLES; PHARMACOKINETICS; PLATINUM; PLATINUM COMPOUNDS; RATS; TOXICITY; TRANSITION METAL COMPOUNDS; TUMORS;

DRUG PRODUCTS;

ANTINEOPLASTIC AGENT; DOCETAXEL; TAXOID;

ANIMAL; ARTICLE; BAGG ALBINO MOUSE; FEMALE; HALF LIFE TIME; METABOLISM; MOUSE; OVARY TUMOR; PATHOLOGY; RAT; SPRAGUE DAWLEY RAT; TISSUE DISTRIBUTION; TRANSMISSION ELECTRON MICROSCOPY;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; FEMALE; HALF-LIFE; MICE; MICE, INBRED BALB C; MICROSCOPY, ELECTRON, TRANSMISSION; OVARIAN NEOPLASMS; RATS; RATS, SPRAGUE-DAWLEY; TAXOIDS; TISSUE DISTRIBUTION;

EID: 79952109342     PISSN: 15334880     EISSN: None     Source Type: Journal    
DOI: 10.1166/jnn.2010.2819     Document Type: Conference Paper

References (16)

1. A. Jemal, R. Siegel, E. Ward, T. Murray, J. Q. Xu, and M. J. Thun, CA-Cancer J. Clin. 57, 43 (2007).
2. M. J. Hawkins, P. Soon-Shiong, and N. Desai, Adv. Drug Deliv. Rev. 60, 76 (2008).
3. N. Katsumata, Br J. Cancer 89, S9 (2003).
4. M. L. Immordino, P. Brusa, S. Arpicco, B. Stella, F Dosio, and L. Cattel, J. Control. Release 91, 417 (2003).
5. H. Y. Hwang, I. S. Kim, I. C. Kwon, and Y. H. Kim, J. Control. Release 128, 23 (2008).
6. M. Elsabahy, M. E. Perron, N. Bertrand, G. E. Yu, and J. C. Leroux, Biomacromolecules 8, 2250 (2007).
7. D. Wang and L. Li, Docetaxel Suhmicron emulsion injection and its preparation methods, CN Patent CN100998559-A, July (2007).
8. R. H. Muller, Adv. Drug Deliv. Rev. 59, 375 (2007).
9. M. K. Lee, S. J. Lim, and C. K. Kim, Biomaterials 28, 2137 (2007).
10. X. Y. Tong, J. P. Zhou, and Y. Tan, Rapid Commun. Mass Spectrom. 20, 1905 (2006).
11. D. Le Garrec, S. Gori, L. Luo, D. Lessard, D. C. Smith, M. A. Yessine, M. Ranger, and J. C. Leroux, J. Control, Release 99, 83 (2004).
12. F Liu and D. Liu, Pharm. Res. 12, 1060 (1995).
13. W. H. De Jong, W. I. Hagens, P. Krystek, M. C. Burger, A. J. A. M. Sips, and R. E. Geertsma, Biomaterials 29, 1912 (2008).
14. S. D. Li and L. Huang, Mol. Pharm. 5, 496 (2008).
15. Y. Lu, J. Li, and G. J. Wang, Int. J. Pharm. 356, 274 (2008).
16. G. Storm, S. O. Belliot, T. Daemen, and D. D. Lasic, Adv. Drug Deliv. Rev. 17, 31(1995).