Early assessment of treatment response in patients with AML using [18F]FLT PET imaging

Leukemia Research

Volumn 35, Issue 3, 2011, Pages 310-316

  Vanderhoek, Matt ^a   Juckett, Mark B ^a   Perlman, Scott B ^b   Nickles, Robert J ^a   Jeraj, Robert ^a  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

3 Deoxy 3 fluorothymidine; 18F FLT; Acute myeloid leukemia (AML); FLT; Positron emission tomography (PET); Radionuclide imaging; Treatment response

Indexed keywords

3' FLUOROTHYMIDINE F 18; CYTARABINE; FLUDARABINE; GEMTUZUMAB OZOGAMICIN; IDARUBICIN;

ACUTE GRANULOCYTIC LEUKEMIA; ADULT; AGED; ARTICLE; BONE MARROW; CANCER CHEMOTHERAPY; CLINICAL ARTICLE; COMPUTER ASSISTED EMISSION TOMOGRAPHY; CONTROLLED STUDY; DRUG UPTAKE; FEMALE; FOLLOW UP; HUMAN; IMAGE ANALYSIS; LEUKEMIA REMISSION; MALE; OUTCOME ASSESSMENT; PILOT STUDY; PRIORITY JOURNAL; TREATMENT RESPONSE; WHOLE BODY TOMOGRAPHY;

ADULT; AGED; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CASE-CONTROL STUDIES; CYTARABINE; FEMALE; FLUORINE RADIOISOTOPES; FLUORODEOXYGLUCOSE F18; HUMANS; IDARUBICIN; LEUKEMIA, MYELOID, ACUTE; MALE; MIDDLE AGED; POSITRON-EMISSION TOMOGRAPHY; RADIOPHARMACEUTICALS; SURVIVAL RATE; TREATMENT OUTCOME; YOUNG ADULT;

EID: 79952107265     PISSN: 01452126     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.leukres.2010.06.010     Document Type: Article

References (20)

1. DeVita V.T., Hellman S., Rosenberg S.A. Cancer, principles & practice of oncology 2005, Lippincott Williams & Wilkins, Philadelphia, PA.
2. Cheson B.D., Bennett J.M., Kopecky K.J., et al. Revised recommendations of the international working group for diagnosis, standardization of response criteria, treatment outcomes, and reporting standards for therapeutic trials in acute myeloid leukemia. J Clin Oncol 2003, 21:4642-4649.
3. Hiddemann W., Clarkson B.D., Buchner T., et al. Bone marrow cell count per cubic millimeter bone marrow: a new parameter for quantitating therapy-induced cytoreduction in acute leukemia. Blood 1982, 59:216-225.
4. Buck A.K., Kratochwil C., Glatting G., et al. Early assessment of therapy response in malignant lymphoma with the thymidine analogue [18F]FLT. Eur J Nucl Med Mol Imaging 2007, 34:1775-1782.
5. Pio B.S., Park C.K., Pietras R., et al. Usefulness of 3′-[F-18]fluoro-3′-deoxythymidine with positron emission tomography in predicting breast cancer response to therapy. Mol Imaging Biol 2006, 8:36-42.
6. Kenny L., Coombes R.C., Vigushin D.M., et al. Imaging early changes in proliferation at 1 week post chemotherapy: a pilot study in breast cancer patients with 3′-deoxy-3′-[18F]fluorothymidine positron emission tomography. Eur J Nucl Med Mol Imaging 2007, 34:1339-1347.
7. Chen W., Delaloye S., Silverman D.H., et al. Predicting treatment response of malignant gliomas to bevacizumab and irinotecan by imaging proliferation with [18F] fluorothymidine positron emission tomography: a pilot study. J Clin Oncol 2007, 25:4714-4721.
8. Herrmann K., Wieder H.A., Buck A.K., et al. Early response assessment using 3′-deoxy-3′-[18F]fluorothymidine-positron emission tomography in high-grade non-Hodgkin's lymphoma. Clin Cancer Res 2007, 13:3552-3558.
9. Shields A.F., Grierson J.R., Dohmen B.M., et al. Imaging proliferation in vivo with [F-18]FLT and positron emission tomography. Nat Med 1998, 4:1334-1336.
10. Vesselle H., Grierson J., Muzi M., et al. In vivo validation of 3′deoxy-3′-[(18)F]fluorothymidine ([(18)F]FLT) as a proliferation imaging tracer in humans: correlation of [(18)F]FLT uptake by positron emission tomography with Ki-67 immunohistochemistry and flow cytometry in human lung tumors. Clin Cancer Res 2002, 8:3315-3323.
11. Shields A.F. PET imaging with 18F-FLT and thymidine analogs: promise and pitfalls. J Nucl Med 2003, 44:1432-1434.
12. Shields A.F., Grierson J.R., Muzik O., et al. Kinetics of 3′-deoxy-3′-[F-18]fluorothymidine uptake and retention in dogs. Mol Imaging Biol 2002, 4:83-89.
13. Agool A., Schot B.W., Jager P.L., Vellenga E. 18F-FLT PET in hematologic disorders: a novel technique to analyze the bone marrow compartment. J Nucl Med 2006, 47:1592-1598.
14. Buck A.K., Bommer M., Juweid M.E., et al. First demonstration of leukemia imaging with the proliferation marker 18F-fluorodeoxythymidine. J Nucl Med 2008, 49:1756-1762.
15. Bennett J.M., Catovsky D., Daniel M.T., et al. Proposed revised criteria for the classification of acute myeloid leukemia. a report of the French-American-British cooperative group. Ann Intern Med 1985, 103:620-625.
16. Jaffe E.S., Harris N.L., Stein H., Vardiman JW World health organization classification of tumors: pathology and genetics of tumors of haematopoietic and lymphoid tissues 2001, IARC Press, Lyon, France, pp. 75-108.
17. Martin S.J., Eisenbarth J.A., Wagner-Utermann U., et al. A new precursor for the radiosynthesis of [18F]FLT. Nucl Med Biol 2002, 29:263-273.
18. Hudson H.M., Larkin R.S. Accelerated image reconstruction using ordered subsets of projection data. IEEE Trans Med Imaging 1994, 13:601-609.
19. Bolard G., Prior J.O., Modolo L., et al. Performance comparison of two commercial BGO-based PET/CT scanners using NEMA NU 2-2001. Med Phys 2007, 34:2708-2717.
20. Kern W., Haferlach T., Schoch C., et al. Early blast clearance by remission induction therapy is a major independent prognostic factor for both achievement of complete remission and long-term outcome in acute myeloid leukemia: data from the German AML cooperative group (AMLCG) 1992 Trial. Blood 2003, 101:64-70.