The protective activity of Saccharum officianarum against CCL4 induced hepatotoxicity in rats

International Journal of Pharmaceutical Research

Volumn 2, Issue 3, 2010, Pages 5-8

  Patel, B A ^a   Patel, J D ^a   Raval, B P ^a   Gandhi, T R ^b  

^a K J College of Pharmacy   (India)

^b ANAND PHARMACY COLLEGE   (India)

Author keywords

Antioxidant; CCl4; Hepatoprotective activity; Juice; Saccharum officinarum

Indexed keywords

ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; BILIRUBIN; CARBON TETRACHLORIDE; GLUTATHIONE; LIVER PROTECTIVE AGENT; MALONALDEHYDE; PLANT EXTRACT; SILYMARIN; SUGARCANE EXTRACT; TRIACYLGLYCEROL; TRYPAN BLUE; UNCLASSIFIED DRUG;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALKALINE PHOSPHATASE BLOOD LEVEL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BILIRUBIN BLOOD LEVEL; CELL SUSPENSION; CELL VIABILITY; CONTROLLED STUDY; FEMALE; HISTOPATHOLOGY; IN VITRO STUDY; IN VIVO STUDY; LIPID PEROXIDATION; LIVER CELL CULTURE; LIVER HOMOGENATE; LIVER TOXICITY; LIVER WEIGHT; MALE; NONHUMAN; PLANT STEM; RAT; SUGARCANE; TRIACYLGLYCEROL BLOOD LEVEL;

EID: 79952097676     PISSN: None     EISSN: 09752366     Source Type: Journal    
DOI: None     Document Type: Article

References (18)

1. Ward FM, Daly MJ. Hepatic disease. In: Walker R, Edwards C, editors. Clinical Pharmacy and Therapeutics Churchill Livingstone: New York; 1999. p. 195-212.
2. Pang S, Xin X, Stpierre MV. Determinants of Metabolic Disposition. Ann Rev Pharmacol Toxicol 1992; 32: 625-6.
3. Ross MH, Romrell LJ, Kaye GI. Histology a text and atlas. Wiliam and Wilkins: Baltimore; 1996.
4. Joaquim M.D.A., Giuseppina N., Antonio S., Carvalho J.E. and Lajolo F.M., Antiproliferative and antioxidant activities of a tricin acylated glycoside from sugarcane (Saccharum officinarum) juice, Phytochemistry 2007; 68 (8); 1165-1171
5. Rao PGM, Rao SG, Kumar V. Effects of Hepatogard against carbon tetrachloride induced liver damage in rats. Fitoterapia 1993; LXIV: 108-13.
6. Tosaki A, Engelman DT, Pali T, Engelman RM, Droy-Lefaix MT. Ginkgo biloba extract (EGb 761) improves postischemic function in isolated preconditioned working rat hearts. Coron Artery Dis 1994; 5: 443-50.
7. Morazzoni P, Bombardelli E. Silybum marianum (Carduus marianus). Fitoterapia 1995; LXIV: 39-42.
8. Reitman S, Frankel S. A colorimetric method for the determination of serum glutamic oxalacetic and glutamic pyruvic transaminases. Am J Clin Pathol 1957;28: 56-63.
9. Szasz G, Quantitative determination of alkaline phosphatase activity in serum and plasma. Ztschr F kinderheilkunde, 1971; 3: 233.
10. Jendrassik L, Grof P. Quantitative determination of total and direct bilirubin in serum and plasma. Biochem Z 1938; 297: 81.
11. Prophet EB, Mills B, Arrington JB, Sobin LH. Laboratory Methods in Histotechnology. Washington DC: Armed Forces Institute of Pathology; 1992.
12. Bancroft JD, Stevens A, Dawson IMS. Theory and practice of Histological Techniques. Edinburgh, London, New York. Churchill-Livingstone 1977.
13. Seglen PO. Preparation of isolated rat liver cells. Methods Cell Biol 1975: 13: 29-83.
14. Johnston DE, Kroening C. Mechanism of early carbon tetrachloride toxicity in cultured rat hepatocytes. Pharmacol Toxicol 1998; 83: 231-39.
15. 3 radical. J Biol Chem 1990; 265: 8392-9.
16. Ohkawa H, Ohishi N, Yagi K. Assay for lipid peroxides. In: Animal tissue by thiobarbituric acid reaction. Anal Biochem 1979; 95: 351-8.
17. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ. Protein measurement with the folin phenol reagent. J Boil Chem. 1951; 193: 265-75.
18. Buetler E, Duron O, Kelly BM. Improved method for determination of blood glutathione. J Lab Clin Med 1963; 61: 882-8.