Characterization of mannose-binding lectin plasma levels and genetic polymorphisms in HIV-1-infected individuals;Caracterização dos polimorfsmos genéticos e dos níveis plasmáticos da lectina ligante de manose em indivíduos infectados pelo HIV-1

Revista da Sociedade Brasileira de Medicina Tropical

Volumn 44, Issue 1, 2011, Pages 1-3

  Vallinoto, Antonio Carlos Rosário ^a   Freitas, Felipe Bonfm ^a   Guirelli, Isabella ^a   Machado, Luiz Fernando Almeida ^a   Azevedo, Vânia Nakauth ^a   Cayres Vallinoto, Izaura ^a   Ishak, Marluísa Oliveira Guimarães ^a   Ishak, Ricardo ^a  

^a FEDERAL UNIVERSITY OF PARÁ   (Brazil)

Author keywords

Amazon region; HIV 1; MBL gene polymorphism

Indexed keywords

GENOMIC DNA; MANNOSE BINDING LECTIN;

ADULT; ARTICLE; BRAZIL; CD4 LYMPHOCYTE COUNT; CONTROLLED STUDY; DNA EXTRACTION; EXON; GENE AMPLIFICATION; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC VARIABILITY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; MAJOR CLINICAL STUDY; PROTEIN BLOOD LEVEL; VIRUS LOAD; VIRUS PATHOGENESIS; WILD TYPE;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 79952080359     PISSN: 00378682     EISSN: None     Source Type: Journal    
DOI: 10.1590/s0037-86822011000100001     Document Type: Article

References (21)

1. Turner MW. The role of mannose-binding lectin in health and disease. Immunobiology 2003; 199:327-339.
2. Madsen HO, Garred P, Tiel S, Kurtzhals JAL, Lamm LU, Ryder LP, et al. Interplay between promoter and structural gene variants control basal serum level of mannan-binding protein. J Immunol 1995; 155:3013-3020.
3. Jüliger S, Luckner D, Mordmüller B, May J, Weierich A, Lell B, et al. Promoter Variants of the Mannose-Binding Lectin Gene Show Different Biding. Biochem Biophys Res Comm 2000; 275:617-622.
4. Madsen HO, Garred P, Kurtzhals JA, Lamm LU, Ryder LP, Tiel S, et al. A new frequent allele is the missing link in the structural polymorphism of the human mannan-binding protein. Immunogenetics 1994; 40:37-44.
5. Kuipers S, Aerts PC, van Dijk H. Diferential microorganism-induced mannose-binding lectin activation. Medical Microbiol Immunol 2003; 36:33-39.
6. Pontes GS, Tamegão-Lopes B, Machado LFA, Azevedo VN, Ishak MOG, Ishak R, et al. Characterization of Mannose-Binding Lectin Gene Polymorphism among Human T-Cell Lymphotropic Virus 1 and 2-Infected Asymptomatic Subjects. Hum Immunol 2005; 66:892-896.
7. Vallinoto ACR, Menezes-Costa MR, Alves AEM, Machado LFA, Azevedo VN, Souza LLB, et al. Mannose-binding lectin gene polymorphism and its impact on human immunodefciency virus 1 infection. Mol Immunol 2006; 43:1358-1362.
8. Alves AEM, Hermes RR, Lopes BPT, Azevedo VN, Machado LFA, Ishak MOG, et al. Polymorphism in the promoter region of the mannose-binding lectin gene among human T-cell lymphotropic virus infected subjects. Mem Instituto Oswaldo Cruz 2007; 102:991-994.
9. Prohászka Z, Tiel S, Ujhelyi E, Szlávik J, Banhegyi D, Füst G. Mannan-binding lectin serum concentrations in HIV-infected patients are infuenced by the stage of disease. Immunol Let 1997; 58:171-175.
10. Garred P, Madsen HO, Balslev U, Hofmann BO, Pedersen C, Gerstof J, et al. Susceptibility to HIV infection and progression of AIDS in relation to variant alleles of mannose-binding lectin. Lancet 1997; 349:236-240.
11. Maas J, Husman AMR, Brouwer M, Krol A, Coutinho R, Keet I, et al. Presence of the variant mannose-binding lectin alleles associated with slower progression to AIDS. AIDS 1998; 12:2275-2280.
12. Vallinoto ACR, Pinheiro da Silva RF, Hermes RH, Amaral ISA, Miranda ECB, Barbosa MSB, et al. Mannose-binding lectin gene polymorphisms are not associated with the susceptibility to HCV infection in the Brazilian Amazon region. Hum Immunol 2009; 70:754-756.
13. Ayres M, Ayres JR, Ayres DL, Santos AS. BioEstat: Aplicação estatística nas áreas das ciências biológicas e médicas [CD-ROM]. Versão 5.0. Belém: Sociedade Civil Mamirauá; 2009.
14. Wong NK, Kojima M, Dobo J, Ambrus G, Sim RB. Activities of the MBL-associated serine proteases (MASPs) and their regulation by natural inhibitors. Mol Immunol 1999; 36:853-861.
15. Turner MW. Mannose-binding lectin (MBL) in health and disease. Immunobiology 1998; 199:327-339.
16. Madsen HO, Satz ML, Hogh B, Svejgaard A, Garred P. Diferent molecular events result in low protein levels of mannan-binding lectin in populations from Southeast Africa and South America. J Immunol 1998; 161:3169-3175.
17. Malik S, Arias M, Di Flumeri C, Garcia LF, Schurr E. Absence of association between mannose-binding lectin gene polymorphisms and HIV-1 infection in a Colombian population. Immunogenetics 2003; 55:49-52.
18. Santos SEB, Guerreiro JF. Te indigenous contribution to the formation of the population of the Brazilian Amazon Region. Rev Bras Genetica 1995; 18:311-315.
19. Nielsen SL, Andersen PL, Koch C, Jensenius JC, Thiel S. The level of the serum opsonin, mannan-binding protein in HIV-1 antibody positive patients. Clin Exp Immunol 1995; 100:219-222.
20. Pastinen T, Liitsola K, Niini P, Alminen M, Syvänen AC. Contribution of the CCR5 and MBL genes susceptibility to HIV type I infection in the Finnish population. AIDS Res Hum Retroviruses 1998; 14:171-175.
21. Catano G, Agan BK, Kulkarni H, Telles V, Marconi VC, Dolan MJ, et al. Independent effects of genetic variations in mannose-binding lectin influence the course of HIV disease: the advantage of heterozygosity for coding mutations. J Infect Dis 2008; 198:72-80.