Stem cell differentiation into steroidogenic cell lineages by NR5A family

Molecular and Cellular Endocrinology

Volumn 336, Issue 1-2, 2011, Pages 123-126

  Miyamoto, Kaoru ^a   Yazawa, Takashi ^a   Mizutani, Tetsuya ^a   Imamichi, Yoshitaka ^a   Kawabe, Shin ya ^a   Kanno, Masafumi ^a   Matsumura, Takahiro ^a   Ju, Yunfeng ^a   Umezawa, Akihiko ^b  

^a UNIVERSITY OF FUKUI   (Japan)

^b NATIONAL RESEARCH INSTITUTE FOR CHILD HEALTH AND DEVELOPMENT   (Japan)

Author keywords

Chromatin; Differentiation; ES cells; LRH 1; SF 1

Indexed keywords

LIVER RECEPTOR HOMOLOG 1; NUCLEAR PROTEIN; PROTEIN NR5A; STEROIDOGENIC FACTOR 1; TETRACYCLINE; UNCLASSIFIED DRUG;

ADRENAL CORTEX CELL; CELL DIFFERENTIATION; CELL LINEAGE; CHROMOSOME STRUCTURE; GENE EXPRESSION REGULATION; MESENCHYMAL STEM CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REVIEW; STEROIDOGENESIS; STEROIDOGENIC CELL; TRANSGENE;

ANIMALS; CELL DIFFERENTIATION; CELL LINEAGE; HUMANS; RECEPTORS, CYTOPLASMIC AND NUCLEAR; STEM CELLS; STEROIDS;

EID: 79952073275     PISSN: 03037207     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mce.2010.11.031     Document Type: Review

References (30)

1. Adams C.C., Workman J.L. Nucleosome displacement in transcription. Cell 1993, 72:305-308.
2. Barrera L.O., Ren B. The transcriptional regulatory code of eukaryotic cells - insights from genome-wide analysis of chromatin organization and transcription factor binding. Curr. Opin. Cell Biol. 2006, 18:291-298.
3. Boerboom D., Pilon N., Behdjani R., Silversides D.W., Sirois J. Expression and regulation of transcripts encoding two members of the NR5A nuclear receptor subfamily of orphan nuclear receptors, steroidogenic factor-1 and NR5A2, in equine ovarian cells during the ovulatory process. Endocrinology 2000, 141:4647-4656.
4. Crawford P.A., Sadovsky Y., Milbrandt J. Nuclear receptor steroidogenic factor 1 directs embryonic stem cells toward the steroidogenic lineage. Mol. Cell. Biol. 1997, 17:3997-4006.
5. Duggavathi R., Volle D.H., Mataki C., Antal M.C., Messaddeq N., Auwerx J., Murphy B.D., Schoonjans K. Liver receptor homolog 1 is essential for ovulation. Genes Dev. 2008, 22:1871-1876.
6. Fayard E., Auwerx J., Schoonjans K. LRH-1: an orphan nuclear receptor involved in development, metabolism and steroidogenesis. Trends Cell Biol. 2004, 14:250-260.
7. Gu P., Goodwin B., Chung A.C.K., Xu X., Wheeler D.A., Price R.R., Galardi C., Peng L., Latour A.M., Koller B.H., et al. Orphan nuclear receptor LRH-1 is required to maintain Oct4 expression at the epiblast stage of embryonic development. Mol. Cell. Biol. 2005, 25:3492-3505.
8. Guo G., Smith A. A genome-wide screen in EpiSCs identifies NR5A nuclear receptors as potent inducers of ground state pluripotency. Development 2010, 137:3185-3192.
9. Heng J.C., Feng B., Han J., Jiang J., Kraus P., Ng J.H., Orlov Y.L., Huss M., Yang L., Lufkin T., et al. The nuclear receptor NR5A2 can replace Oct4 in the reprogramming of murine somatic cells to pluripotent cells. Cell Stem Cell 2010, 6:167-174.
10. Khalfallah O., Rouleau M., Barbry P., Bardoni B., Lalli E. DAX-1 knockdown in mouse embryonic stem cells induces loss of pluripotency and multilineage differentiation. Stem Cells 2009, 27:1529-1537.
11. Krylova I.N., Sablin E.P., Moore J., Xu R.X., Waitt G.M., MacKay J.A., Juzumiene D., Bynum J.M., Madauss K., Montana V., et al. Structural analyses reveal phosphatidyl inositols as ligands for the NR5 orphan receptors SF-1 and LRH-1. Cell 2005, 120:343-355.
12. Labelle-Dumais C., Pare J.-F., Belanger L., Farookhi R., Dufort D. Impaired progesterone production in NR5A2+/- mice leads to a reduction in female reproductive function. Biol. Reprod. 2007, 77:217-225.
13. Lala D.S., Rice D.A., Parker K.L. Steroidogenic factor I, a key regulator of steroidogenic enzyme expression, is the mouse homolog of fushi tarazu-factor I. Mol. Endocrinol. 1992, 6:1249-1258.
14. Lee Y.K., Moore D.D. Liver receptor homolog-1, an emerging metabolic modulator. Front. Biosci. 2008, 13:5950-5958.
15. Li B., Carey M., Workman J.L. The role of chromatin during transcription. Cell 2007, 128:707-719.
16. Masui S., Shimosato D., Toyooka Y., Yagi R., Takahashi K., Niwa H. An efficient system to establish multiple embryonic stem cell lines carrying an inducible expression unit. Nucleic Acids Res. 2005, 33:e43.
17. Mizutani T., Yazawa T., Ju Y., Imamichi Y., Uesaka M., Inaoka Y., Matsuura K., Kamiki Y., Oki M., Umezawa A., et al. Identification of a novel distal control region upstream of the human steroidogenic acute regulatory protein (StAR) gene that participates in SF-1-dependent chromatin architecture. J. Biol. Chem. 2010, 285:28240-28251.
18. Morohashi K., Honda S., Inomata Y., Handa H., Omura T. A common trans-acting factor, Ad4-binding protein, to the promoters of steroidogenic P-450S. J. Biol. Chem. 1992, 267:17913-17919.
19. Niwa H., Miyazaki J., Smith A.G. Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells. Nat. Genet. 2000, 24:372-376.
20. Owen-Hughes T., Workman J.L. Remodeling the chromatin structure of a nucleosome array by transcription factor-targeted trans-displacement of histones. EMBO J. 1996, 15:4702-4712.
21. Parker K.L., Schimmer B.P. Steroidogenic factor 1: a key determinant of endocrine development and function. Endocr. Rev. 1997, 18:361-377.
22. Sakurai H., Era T., Jakt L.M., Okada M., Nakai S., Nishikawa S., Nishikawa S.-I. In vitro modeling of paraxial and lateral mesoderm differentiation reveals early reversibility. Stem Cells 2006, 24:575-586.
23. Saxena D., Escamilla-Hernandez R., Little-Ihrig L., Zeleznik A.J. Liver receptor homolog-1 and steroidogenic factor-1 have similar actions on rat granulosa cell steroidogenesis. Endocrinology 2007, 148:726-734.
24. Sun C., Nakatake Y., Akagi T., Ura H., Matsuda T., Nishiyama A., Koide H., Ko M.S., Niwa H., Yokota T. Dax1 binds to Oct3/4 and inhibits its transcriptional activity in embryonic stem cells. Mol. Cell. Biol. 2009, 29:4574-4583.
25. Takashima Y., Era T., Nakao K., Kondo S., Kasuga M., Smith A.G., Nishikawa S.-I. Neuroepithelial cells supply an initial transient wave of MSC differentiation. Cell 2007, 129:1377-1388.
26. Vicent G.P., Nacht A.S., Smith C.L., Peterson C.L., Dimitrov S., Beato M. DNA instructed displacement of histones H2A and H2B at an inducible promoter. Mol. Cell 2004, 16:439-452.
27. Volle D.H., Duggavathi R., Magnier B.C., Houten S.M., Cummins C.L., Lobaccaro J-MA, Verhoeven G., Schoonjans K., Auwerx J. The small heterodimer partner is a gonadal gatekeeper of sexual maturation in male mice. Genes Dev. 2007, 21:303-315.
28. Yazawa T., Inanoka Y., Mizutani T., Kuribayashi M., Umezawa A., Miyamoto K. Liver receptor homolog-1 regulates the transcription of steroidogenic enzymes and induces the differentiation of mesenchymal stem cells into steroidogenic cells. Endocrinology 2009, 150:3885-3893.
29. Yazawa T., Mizutani T., Yamada K., Kawata H., Sekiguchi T., Yoshino M., Kajitani T., Shou Z., Umezawa A., Miyamoto K. Differentiation of adult stem cells derived from bone marrow stroma into Leydig or adrenocortical cells. Endocrinology 2006, 147:4104-4111.
30. Yu R.N., Achermann J.C., Ito M., Jameson J.L. The role of DAX-1 in reproduction. Trends Endocrinol. Metab. 1998, 9:169-175.