메뉴 건너뛰기




Volumn 40, Issue 1, 2011, Pages 210-218

Epidemiology-based risk assessment using the benchmark dose/margin of exposure approach: The example of ethanol and liver cirrhosis

Author keywords

Alcohol; Alcoholic beverages; Benchmark dose; Dose response relationship; Epidemiological methods; Ethanol; Liver cirrhosis; Margin of exposure; Risk assessment

Indexed keywords

ALCOHOL; BENCHMARKING; DIGESTIVE SYSTEM DISORDER; DOSE-RESPONSE RELATIONSHIP; EPIDEMIOLOGY; ETHANOL; HEALTH POLICY; MORTALITY; PUBLIC HEALTH; RISK ASSESSMENT;

EID: 79952060839     PISSN: 03005771     EISSN: 14643685     Source Type: Journal    
DOI: 10.1093/ije/dyq150     Document Type: Article
Times cited : (41)

References (65)
  • 1
    • 0033390550 scopus 로고    scopus 로고
    • The relationship between alcohol consumption, health indicators and mortality in the German population
    • Hoffmeister H, Schelp FP, Mensink GB, Dietz E, Böhning D. The relationship between alcohol consumption, health indicators and mortality in the German population. Int J Epidemiol 1999;28: 1066-72.
    • (1999) Int J Epidemiol , vol.28 , pp. 1066-1072
    • Hoffmeister, H.1    Schelp, F.P.2    Mensink, G.B.3    Dietz, E.4    Böhning, D.5
  • 3
    • 52449119949 scopus 로고    scopus 로고
    • Method for moderation: Measuring lifetime risk of alcohol-attributable mortality as a basis for drinking guidelines
    • Rehm J, Room R, Taylor B. Method for moderation: measuring lifetime risk of alcohol-attributable mortality as a basis for drinking guidelines. Int J Methods Psychiatr Res 2008;17:141-51.
    • (2008) Int J Methods Psychiatr Res , vol.17 , pp. 141-151
    • Rehm, J.1    Room, R.2    Taylor, B.3
  • 4
    • 2942711681 scopus 로고    scopus 로고
    • Derivation of tolerable upper alcohol intake levels in Germany: A systematic review of risks and benefits of moderate alcohol consumption
    • Burger M, Brönstrup A, Pietrzik K. Derivation of tolerable upper alcohol intake levels in Germany: a systematic review of risks and benefits of moderate alcohol consumption. Prev Med 2004;39:111-27.
    • (2004) Prev Med , vol.39 , pp. 111-127
    • Burger, M.1    Brönstrup, A.2    Pietrzik, K.3
  • 5
    • 0344505272 scopus 로고    scopus 로고
    • Methods for health risk assessment of chemicals: Are they relevant for alcohol?
    • Victorin K, Haag-Grönlund M, Skerfving S. Methods for health risk assessment of chemicals: are they relevant for alcohol? Alcohol Clin Exp Res 1998;22:270S-6S.
    • (1998) Alcohol Clin Exp Res , vol.22
    • Victorin, K.1    Haag-Grönlund, M.2    Skerfving, S.3
  • 6
    • 0017750841 scopus 로고
    • The toxicity of ethanol. A tentative risk evaluation
    • Rydberg U, Skerfving S. The toxicity of ethanol. A tentative risk evaluation. Adv Exp Med Biol 1977;85B:403-19.
    • (1977) Adv Exp Med Biol , vol.85 B , pp. 403-419
    • Rydberg, U.1    Skerfving, S.2
  • 7
    • 26444504695 scopus 로고    scopus 로고
    • Measuring alcohol consumption
    • Gmel G, Rehm J. Measuring alcohol consumption. Contemp Drug Probl 2004;31:467-540.
    • (2004) Contemp Drug Probl , vol.31 , pp. 467-540
    • Gmel, G.1    Rehm, J.2
  • 8
    • 34247562350 scopus 로고    scopus 로고
    • Communicating through government agencies
    • Harding R, Stockley CS. Communicating through government agencies. Ann Epidemiol 2007;17:S98-102.
    • (2007) Ann Epidemiol , vol.17
    • Harding, R.1    Stockley, C.S.2
  • 9
    • 0029828753 scopus 로고    scopus 로고
    • On the emerging paradigm of drinking patterns and their social and health consequences
    • Rehm J, Ashley MJ, Room R et al. On the emerging paradigm of drinking patterns and their social and health consequences. Addiction 1996;91:1615-21.
    • (1996) Addiction , vol.91 , pp. 1615-1621
    • Rehm, J.1    Ashley, M.J.2    Room, R.3
  • 10
    • 34247624006 scopus 로고    scopus 로고
    • Carcinogenicity of alcoholic beverages
    • Baan R, Straif K, Grosse Y et al. Carcinogenicity of alcoholic beverages. Lancet Oncol 2007;8:292-3.
    • (2007) Lancet Oncol , vol.8 , pp. 292-293
    • Baan, R.1    Straif, K.2    Grosse, Y.3
  • 11
    • 0037132383 scopus 로고    scopus 로고
    • Alcohol, tobacco and breast cancer - collaborative reanalysis of individual data from 53 epidemiological studies, including 58,515 women with breast cancer and 95,067 women without the disease
    • Hamajima N, Hirose K, Tajima K et al. Alcohol, tobacco and breast cancer - collaborative reanalysis of individual data from 53 epidemiological studies, including 58,515 women with breast cancer and 95,067 women without the disease. Br J Cancer 2002;87:1234-45.
    • (2002) Br J Cancer , vol.87 , pp. 1234-1245
    • Hamajima, N.1    Hirose, K.2    Tajima, K.3
  • 12
    • 77950670865 scopus 로고    scopus 로고
    • The relation between different dimensions of alcohol consumption and burden of disease: An overview
    • Rehm J, Baliunas D, Borges GLG et al. The relation between different dimensions of alcohol consumption and burden of disease: an overview. Addiction 2010;105: 817-43.
    • (2010) Addiction , vol.105 , pp. 817-843
    • Rehm, J.1    Baliunas, D.2    Borges, G.L.G.3
  • 13
    • 74249103316 scopus 로고    scopus 로고
    • Using the Benchmark Dose (BMD) Methodology to determine an appropriate reduction of certain ingredients in food products
    • Bi J. Using the Benchmark Dose (BMD) Methodology to determine an appropriate reduction of certain ingredients in food products. J Food Sci 2010;75:R9-16.
    • (2010) J Food Sci , vol.75
    • Bi, J.1
  • 14
    • 77957180789 scopus 로고
    • A new method for determining allowable daily intakes
    • Crump KS. A new method for determining allowable daily intakes. Fundam Appl Toxicol 1984;4:854-71.
    • (1984) Fundam Appl Toxicol , vol.4 , pp. 854-871
    • Crump, K.S.1
  • 15
    • 0003788952 scopus 로고
    • US EPA, EPA/630/R-94/007. Washington, DC: Office of Research and Development. US Environmental Protection Agency
    • US EPA. The Use of the Benchmark Dose Approach in Health Risk Assessment. EPA/630/R-94/007. Washington, DC: Office of Research and Development. US Environmental Protection Agency, 1995.
    • (1995) The Use of the Benchmark Dose Approach in Health Risk Assessment
  • 16
    • 33748659067 scopus 로고    scopus 로고
    • Opinion of the Scientific Committee on a request from EFSA related to a harmonised approach for risk assessment of substances which are both genotoxic and carcinogenic
    • EFSA
    • EFSA. Opinion of the Scientific Committee on a request from EFSA related to a harmonised approach for risk assessment of substances which are both genotoxic and carcinogenic. EFSA J 2005;282:1-31.
    • (2005) EFSA J , vol.282 , pp. 1-31
  • 17
    • 70449533835 scopus 로고    scopus 로고
    • The benchmark dose approach in food risk assessment: Is it applicable and worthwhile?
    • Muri SD, Schlatter JR, Brüschweiler BJ. The benchmark dose approach in food risk assessment: is it applicable and worthwhile? Food Chem Toxicol 2009;47:2906-25.
    • (2009) Food Chem Toxicol , vol.47 , pp. 2906-2925
    • Muri, S.D.1    Schlatter, J.R.2    Brüschweiler, B.J.3
  • 18
    • 0042474469 scopus 로고    scopus 로고
    • Assessment of potential risk levels associated with U.S. environmental protection agency reference values
    • Castorina R, Woodruff TJ. Assessment of potential risk levels associated with U.S. environmental protection agency reference values. Environ Health Perspect 2003; 111:1318-25.
    • (2003) Environ Health Perspect , vol.111 , pp. 1318-1325
    • Castorina, R.1    Woodruff, T.J.2
  • 19
    • 44149087583 scopus 로고    scopus 로고
    • The current state of knowledge on the use of the benchmark dose concept in risk assessment
    • Sand S, Victorin K, Filipsson AF. The current state of knowledge on the use of the benchmark dose concept in risk assessment. J Appl Toxicol 2008;28:405-21.
    • (2008) J Appl Toxicol , vol.28 , pp. 405-421
    • Sand, S.1    Victorin, K.2    Filipsson, A.F.3
  • 20
    • 0142010683 scopus 로고    scopus 로고
    • The benchmark dose method - review of available models, and recommendations for application in health risk assessment
    • Filipsson AF, Sand S, Nilsson J, Victorin K. The benchmark dose method - review of available models, and recommendations for application in health risk assessment. Crit Rev Toxicol 2003;33:505-42.
    • (2003) Crit Rev Toxicol , vol.33 , pp. 505-542
    • Filipsson, A.F.1    Sand, S.2    Nilsson, J.3    Victorin, K.4
  • 21
    • 74549215283 scopus 로고    scopus 로고
    • Application of the margin of exposure (MOE) approach to substances in food that are genotoxic and carcinogenic
    • Benford D, Bolger PM, Carthew P et al. Application of the margin of exposure (MOE) approach to substances in food that are genotoxic and carcinogenic. Food Chem Toxicol 2010;48:S2-24.
    • (2010) Food Chem Toxicol , vol.48
    • Benford, D.1    Bolger, P.M.2    Carthew, P.3
  • 22
    • 17144449286 scopus 로고    scopus 로고
    • Benchmark dose calculation from epidemiological data
    • Budtz-Jørgensen E, Keiding N, Grandjean P. Benchmark dose calculation from epidemiological data. Biometrics 2001;57:698-706.
    • (2001) Biometrics , vol.57 , pp. 698-706
    • Budtz-Jørgensen, E.1    Keiding, N.2    Grandjean, P.3
  • 23
    • 0034653355 scopus 로고    scopus 로고
    • Benchmark dose calculations of methylmercury-associated neurobehavioural deficits
    • Budtz-Jørgensen E, Grandjean P, Keiding N, White RF, Weihe P. Benchmark dose calculations of methylmercury-associated neurobehavioural deficits. Toxicol Lett 2000; 112-113:193-99.
    • (2000) Toxicol Lett , vol.112-113 , pp. 193-199
    • Budtz-Jørgensen, E.1    Grandjean, P.2    Keiding, N.3    White, R.F.4    Weihe, P.5
  • 24
    • 0034034185 scopus 로고    scopus 로고
    • Benchmark concentrations for methylmercury obtained from the Seychelles Child Development Study
    • Crump KS, Van Landingham C, Shamlaye C et al. Benchmark concentrations for methylmercury obtained from the Seychelles Child Development Study. Environ Health Perspect 2000;108:257-63.
    • (2000) Environ Health Perspect , vol.108 , pp. 257-263
    • Crump, K.S.1    Van Landingham, C.2    Shamlaye, C.3
  • 25
    • 22344432526 scopus 로고    scopus 로고
    • Benchmark dose estimation based on epidemiologic cohort data
    • Morales KH, Ryan LM. Benchmark dose estimation based on epidemiologic cohort data. Environmetrics 2005;16: 435-47.
    • (2005) Environmetrics , vol.16 , pp. 435-447
    • Morales, K.H.1    Ryan, L.M.2
  • 26
    • 33645521652 scopus 로고    scopus 로고
    • Bayesian model averaging with applications to benchmark dose estimation for arsenic in drinking water
    • Morales KH, Ibrahim JG, Chen CJ, Ryan LM. Bayesian model averaging with applications to benchmark dose estimation for arsenic in drinking water. J Am Stat Assoc 2006;101:9-17.
    • (2006) J Am Stat Assoc , vol.101 , pp. 9-17
    • Morales, K.H.1    Ibrahim, J.G.2    Chen, C.J.3    Ryan, L.M.4
  • 27
    • 17944383442 scopus 로고    scopus 로고
    • Environmental epidemiological study and estimation of benchmark dose for renal dysfunction in a cadmium-polluted area in China
    • Jin T, Wu X, Tang Y et al. Environmental epidemiological study and estimation of benchmark dose for renal dysfunction in a cadmium-polluted area in China. Biometals 2004;17:525-30.
    • (2004) Biometals , vol.17 , pp. 525-530
    • Jin, T.1    Wu, X.2    Tang, Y.3
  • 28
    • 33645879522 scopus 로고    scopus 로고
    • Risk estimation for carcinogens based on epidemio-logical data: A structured approach, illustrated by an example on chromium
    • Goldbohm RA, Tielemans EL, Heederik D et al. Risk estimation for carcinogens based on epidemio-logical data: a structured approach, illustrated by an example on chromium. Regul Toxicol Pharmacol 2006;44: 294-310.
    • (2006) Regul Toxicol Pharmacol , vol.44 , pp. 294-310
    • Goldbohm, R.A.1    Tielemans, E.L.2    Heederik, D.3
  • 29
    • 45949099124 scopus 로고    scopus 로고
    • Application of benchmark dose for occupational epidemiology in lead exposure
    • Lin T, Xiao-Ting L, Ai G, Qiu-Ying L, Tai-Yi J. Application of benchmark dose for occupational epidemiology in lead exposure. Toxicol Mech Methods 2008;18:363-67.
    • (2008) Toxicol Mech Methods , vol.18 , pp. 363-367
    • Lin, T.1    Xiao-Ting, L.2    Ai, G.3    Qiu-Ying, L.4    Tai-Yi, J.5
  • 30
    • 59649084689 scopus 로고    scopus 로고
    • Benchmark calculations from summarized data: An example
    • Crump KS, Teeguarden JG. Benchmark calculations from summarized data: an example. Environ Ecol Stat 2009;16: 13-24.
    • (2009) Environ Ecol Stat , vol.16 , pp. 13-24
    • Crump, K.S.1    Teeguarden, J.G.2
  • 31
    • 0031417919 scopus 로고    scopus 로고
    • Estimating benchmark concentrations and other non-cancer endpoints in epidemiology studies
    • Bailer AJ, Stayner LT, Smith RJ, Kuempel ED, Prince MM. Estimating benchmark concentrations and other non-cancer endpoints in epidemiology studies. Risk Anal 1997; 17:771-80.
    • (1997) Risk Anal , vol.17 , pp. 771-780
    • Bailer, A.J.1    Stayner, L.T.2    Smith, R.J.3    Kuempel, E.D.4    Prince, M.M.5
  • 32
    • 1642544728 scopus 로고    scopus 로고
    • Effects of alcohol consumption on hepatocellular injury in Japanese men
    • Dakeishi M, Iwata T, Ishii N, Murata K. Effects of alcohol consumption on hepatocellular injury in Japanese men. Tohoku J Exp Med 2004;202:31-39.
    • (2004) Tohoku J Exp Med , vol.202 , pp. 31-39
    • Dakeishi, M.1    Iwata, T.2    Ishii, N.3    Murata, K.4
  • 33
    • 33645107133 scopus 로고    scopus 로고
    • Relation between benchmark dose and no-observed-adverse-effect level in clinical research: Effects of daily alcohol intake on blood pressure in Japanese salesmen
    • Dakeishi M, Murata K, Tamura A, Iwata T. Relation between benchmark dose and no-observed-adverse-effect level in clinical research: effects of daily alcohol intake on blood pressure in Japanese salesmen. Risk Anal 2006;26: 115-23.
    • (2006) Risk Anal , vol.26 , pp. 115-123
    • Dakeishi, M.1    Murata, K.2    Tamura, A.3    Iwata, T.4
  • 34
    • 61449263679 scopus 로고    scopus 로고
    • Ethyl Carbamate in Alcoholic Beverages from Mexico (Tequila, Mezcal, Bacanora, Sotol) and Guatemala (Cuxa): Market Survey and Risk Assessment
    • Lachenmeier DW, Kanteres F, Kuballa T, López MG, Rehm J. Ethyl Carbamate in Alcoholic Beverages from Mexico (Tequila, Mezcal, Bacanora, Sotol) and Guatemala (Cuxa): Market Survey and Risk Assessment. Int J Environ Res Public Health 2009;6:349-60.
    • (2009) Int J Environ Res Public Health , vol.6 , pp. 349-360
    • Lachenmeier, D.W.1    Kanteres, F.2    Kuballa, T.3    López, M.G.4    Rehm, J.5
  • 35
    • 62649102275 scopus 로고    scopus 로고
    • Carcinogenicity of acetaldehyde in alcoholic beverages: Risk assessment outside ethanol metabolism
    • Lachenmeier DW, Kanteres F, Rehm J. Carcinogenicity of acetaldehyde in alcoholic beverages: risk assessment outside ethanol metabolism. Addiction 2009;104:533-50.
    • (2009) Addiction , vol.104 , pp. 533-550
    • Lachenmeier, D.W.1    Kanteres, F.2    Rehm, J.3
  • 36
    • 61449231106 scopus 로고    scopus 로고
    • Ethyl carbamate and hydrocyanic acid in food and beverages
    • EFSA
    • EFSA. Ethyl carbamate and hydrocyanic acid in food and beverages. EFSA J 2007;551:1-44.
    • (2007) EFSA J , vol.551 , pp. 1-44
  • 37
    • 77953126256 scopus 로고    scopus 로고
    • Cancer risk assessment of ethyl carbamate in alcoholic beverages from Brazil with special consideration to the spirits cachaca and tiquira
    • Lachenmeier DW, Lima MC, Nobrega IC et al. Cancer risk assessment of ethyl carbamate in alcoholic beverages from Brazil with special consideration to the spirits cachaca and tiquira. BMC Cancer 2010;10:266.
    • (2010) BMC Cancer , vol.10 , pp. 266
    • Lachenmeier, D.W.1    Lima, M.C.2    Nobrega, I.C.3
  • 39
    • 67649116613 scopus 로고    scopus 로고
    • Global burden of disease and injury and economic cost attributable to alcohol use and alcohol-use disorders
    • Rehm J, Mathers C, Popova S, Thavorncharoensap M, Teerawattananon Y, Patra J. Global burden of disease and injury and economic cost attributable to alcohol use and alcohol-use disorders. Lancet 2009;373:2223-33.
    • (2009) Lancet , vol.373 , pp. 2223-2233
    • Rehm, J.1    Mathers, C.2    Popova, S.3    Thavorncharoensap, M.4    Teerawattananon, Y.5    Patra, J.6
  • 40
    • 77953808099 scopus 로고    scopus 로고
    • Alcohol as a risk factor for liver cirrhosis - a systematic review and meta-analysis
    • Rehm J, Taylor B, Mohapatra S et al. Alcohol as a risk factor for liver cirrhosis - a systematic review and meta-analysis. Drug Alcohol Rev 2010;29:437-45.
    • (2010) Drug Alcohol Rev , vol.29 , pp. 437-445
    • Rehm, J.1    Taylor, B.2    Mohapatra, S.3
  • 42
    • 0034101572 scopus 로고    scopus 로고
    • Long-term ethanol consumption in ICR mice causes mammary tumor in females and liver fibrosis in males
    • Watabiki T, Okii Y, Tokiyasu T et al. Long-term ethanol consumption in ICR mice causes mammary tumor in females and liver fibrosis in males. Alcohol Clin Exp Res 2000;24:117S-22S.
    • (2000) Alcohol Clin Exp Res , vol.24
    • Watabiki, T.1    Okii, Y.2    Tokiyasu, T.3
  • 43
    • 0029059281 scopus 로고
    • Hepatic fibrosis produced in guinea pigs by chronic ethanol administration and immunization with acetaldehyde adducts
    • Yokoyama H, Nagata S, Moriya S et al. Hepatic fibrosis produced in guinea pigs by chronic ethanol administration and immunization with acetaldehyde adducts. Hepatology 1995;21:1438-42.
    • (1995) Hepatology , vol.21 , pp. 1438-1442
    • Yokoyama, H.1    Nagata, S.2    Moriya, S.3
  • 44
    • 0028863402 scopus 로고
    • Ethanol-related liver injury in the rat: A model of steatosis, inflammation and pericentral fibrosis
    • Keegan A, Martini R, Batey R. Ethanol-related liver injury in the rat: a model of steatosis, inflammation and pericentral fibrosis. J Hepatol 1995;23:591-600.
    • (1995) J Hepatol , vol.23 , pp. 591-600
    • Keegan, A.1    Martini, R.2    Batey, R.3
  • 45
    • 0027310211 scopus 로고
    • Effect of ethanol on cytochrome P450 2E1 (CYP2E1), lipid peroxidation, and serum protein adduct formation in relation to liver pathology pathogenesis
    • French SW, Wong K, Jui L, Albano E, Hagbjork AL, Ingelman-Sundberg M. Effect of ethanol on cytochrome P450 2E1 (CYP2E1), lipid peroxidation, and serum protein adduct formation in relation to liver pathology pathogenesis. Exp Mol Pathol 1993;58:61-75.
    • (1993) Exp Mol Pathol , vol.58 , pp. 61-75
    • French, S.W.1    Wong, K.2    Jui, L.3    Albano, E.4    Hagbjork, A.L.5    Ingelman-Sundberg, M.6
  • 46
    • 0022830407 scopus 로고
    • Ethanol-induced hepatic fibrosis in the rat: Role of the amount of dietary fat
    • French SW, Miyamoto K, Tsukamoto H. Ethanol-induced hepatic fibrosis in the rat: role of the amount of dietary fat. Alcohol Clin Exp Res 1986;10:13S-9S.
    • (1986) Alcohol Clin Exp Res , vol.10
    • French, S.W.1    Miyamoto, K.2    Tsukamoto, H.3
  • 47
    • 0036965323 scopus 로고    scopus 로고
    • Results of long-term experimental studies on the carcinogenicity of methyl alcohol and ethyl alcohol in rats
    • Soffritti M, Belpoggi F, Cevolani D, Guarino M, Padovani M, Maltoni C. Results of long-term experimental studies on the carcinogenicity of methyl alcohol and ethyl alcohol in rats. Ann N Y Acad Sci 2002;982: 46-69.
    • (2002) Ann N Y Acad Sci , vol.982 , pp. 46-69
    • Soffritti, M.1    Belpoggi, F.2    Cevolani, D.3    Guarino, M.4    Padovani, M.5    Maltoni, C.6
  • 48
    • 77954309272 scopus 로고    scopus 로고
    • Studies of urethane, ethanol, and urethane/ethanol (urethane, CAS No. 51-79-6; ethanol, CAS No. 64-17-5) in B6C3F1 mice (drinking water studies)
    • NTP technical report on the toxicology and carcinogensis
    • NTP technical report on the toxicology and carcinogensis. Studies of urethane, ethanol, and urethane/ethanol (urethane, CAS No. 51-79-6; ethanol, CAS No. 64-17-5) in B6C3F1 mice (drinking water studies). Natl Toxicol Program Tech Rep Ser 2004;510:1-346.
    • (2004) Natl Toxicol Program Tech Rep Ser , vol.510 , pp. 1-346
  • 50
    • 79551657823 scopus 로고    scopus 로고
    • WHO. Geneva, Switzerland. World Health Organization,(1 September 2010, date last accessed)
    • WHO. Global Information System on Alcohol and Health. Geneva, Switzerland. http://www.who.int/globalatlas/default.asp. World Health Organization, 2009 (1 September 2010, date last accessed).
    • (2009) Global Information System on Alcohol and Health
  • 51
    • 0042198135 scopus 로고    scopus 로고
    • The global distribution of average volume of alcohol consumption and patterns of drinking
    • Rehm J, Rehn N, Room R et al. The global distribution of average volume of alcohol consumption and patterns of drinking. Eur Addict Res 2003;9:147-56.
    • (2003) Eur Addict Res , vol.9 , pp. 147-156
    • Rehm, J.1    Rehn, N.2    Room, R.3
  • 53
    • 34250626368 scopus 로고    scopus 로고
    • Comparative quantification of alcohol exposure as risk factor for global burden of disease
    • Rehm J, Klotsche J, Patra J. Comparative quantification of alcohol exposure as risk factor for global burden of disease. Int J Methods Psychiatr Res 2007;16: 66-76.
    • (2007) Int J Methods Psychiatr Res , vol.16 , pp. 66-76
    • Rehm, J.1    Klotsche, J.2    Patra, J.3
  • 54
    • 84855753956 scopus 로고    scopus 로고
    • CAMH, Toronto, Canada: Centre for Addiction and Mental Health
    • CAMH. Low-Risk Drinking Guidelines [pamphlet]. Toronto, Canada: Centre for Addiction and Mental Health, 2005.
    • (2005) Low-Risk Drinking Guidelines [pamphlet]
  • 57
    • 13844305795 scopus 로고    scopus 로고
    • Comparison of carcinogen hazard characterisation based on animal studies and epidemiology
    • Sanner T, Dybing E. Comparison of carcinogen hazard characterisation based on animal studies and epidemiology. Basic Clin Pharmacol Toxicol 2005;96:66-70.
    • (2005) Basic Clin Pharmacol Toxicol , vol.96 , pp. 66-70
    • Sanner, T.1    Dybing, E.2
  • 58
    • 0034667549 scopus 로고    scopus 로고
    • Dose response of laboratory markers to alcohol consumption in a general population
    • Sillanaukee P, Massot N, Jousilahti P et al. Dose response of laboratory markers to alcohol consumption in a general population. Am J Epidemiol 2000;152:747-51.
    • (2000) Am J Epidemiol , vol.152 , pp. 747-751
    • Sillanaukee, P.1    Massot, N.2    Jousilahti, P.3
  • 59
    • 65549148663 scopus 로고    scopus 로고
    • Unrecorded alcohol: A threat to public health?
    • Lachenmeier DW, Rehm J. Unrecorded alcohol: a threat to public health? Addiction 2009;104:875-77.
    • (2009) Addiction , vol.104 , pp. 875-877
    • Lachenmeier, D.W.1    Rehm, J.2
  • 61
    • 77953019840 scopus 로고    scopus 로고
    • Association of polymorphism in alcohol dehydrogenase and interaction with other genetic risk factors with alcoholic liver cirrhosis
    • Khan AJ, Husain Q, Choudhuri G, Parmar D. Association of polymorphism in alcohol dehydrogenase and interaction with other genetic risk factors with alcoholic liver cirrhosis. Drug Alcohol Depend 2010;109:190-97.
    • (2010) Drug Alcohol Depend , vol.109 , pp. 190-197
    • Khan, A.J.1    Husain, Q.2    Choudhuri, G.3    Parmar, D.4
  • 62
    • 2142650784 scopus 로고    scopus 로고
    • Overview of the role of alcohol dehydrogenase and aldehyde dehydro-genase and their variants in the genesis of alcohol-related pathology
    • Crabb DW, Matsumoto M, Chang D, You M. Overview of the role of alcohol dehydrogenase and aldehyde dehydro-genase and their variants in the genesis of alcohol-related pathology. Proc Nutr Soc 2004;63:49-63.
    • (2004) Proc Nutr Soc , vol.63 , pp. 49-63
    • Crabb, D.W.1    Matsumoto, M.2    Chang, D.3    You, M.4
  • 63
    • 58749083040 scopus 로고    scopus 로고
    • Alcohol and genetic polymorphisms: Effect on risk of alcohol-related cancer
    • Druesne-Pecollo N, Tehard B, Mallet Y et al. Alcohol and genetic polymorphisms: effect on risk of alcohol-related cancer. Lancet Oncol 2009;10:173-80.
    • (2009) Lancet Oncol , vol.10 , pp. 173-180
    • Druesne-Pecollo, N.1    Tehard, B.2    Mallet, Y.3
  • 64


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.