Tiotropium bromide inhibits TGF-β-induced MMP production from lung fibroblasts by interfering with Smad and MAPK pathways in vitro.

International journal of chronic obstructive pulmonary disease

Volumn 5, Issue , 2010, Pages 277-286

  Asano, Kazuhito ^a   Shikama, Yusuke ^b   Shoji, Naruo ^b   Hirano, Kojiro ^b   Suzaki, Harumi ^b   Nakajima, Hiroaki ^b  

^a SHOWA UNIVERSITY   (Japan)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

BRONCHODILATING AGENT; MATRIX METALLOPROTEINASE; SCOPOLAMINE DERIVATIVE; SMAD2 PROTEIN; TIOTROPIUM BROMIDE; TRANSFORMING GROWTH FACTOR BETA;

ADULT; AGED; ARTICLE; CHRONIC OBSTRUCTIVE LUNG DISEASE; CULTURE TECHNIQUE; DRUG ANTAGONISM; DRUG EFFECT; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FIBROBLAST; HUMAN; IN VITRO STUDY; LUNG; MALE; METABOLISM; METHODOLOGY; MIDDLE AGED; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION;

ADULT; AGED; BASE SEQUENCE; BRONCHODILATOR AGENTS; CELL CULTURE TECHNIQUES; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FIBROBLASTS; HUMANS; LUNG; MALE; MATRIX METALLOPROTEINASES; MIDDLE AGED; POLYMERASE CHAIN REACTION; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; SCOPOLAMINE DERIVATIVES; SMAD2 PROTEIN; TRANSFORMING GROWTH FACTOR BETA;

MLCS; MLOWN;

EID: 79952056758     PISSN: None     EISSN: 11782005     Source Type: Journal    
DOI: 10.2147/copd.s11737     Document Type: Article

References (0)