메뉴 건너뛰기




Volumn 6, Issue 2, 2011, Pages

Determination of beta-defensin genomic copy number in different populations: A comparison of three methods

Author keywords

[No Author keywords available]

Indexed keywords

BETA DEFENSIN; DNA;

EID: 79952048505     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0016768     Document Type: Article
Times cited : (41)

References (55)
  • 1
    • 33751329250 scopus 로고    scopus 로고
    • Global variation in copy number in the human genome
    • Redon R, Ishikawa S, Fitch KR, Feuk L, Perry GH, et al. (2006) Global variation in copy number in the human genome. Nature 444: 444-454.
    • (2006) Nature , vol.444 , pp. 444-454
    • Redon, R.1    Ishikawa, S.2    Fitch, K.R.3    Feuk, L.4    Perry, G.H.5
  • 2
    • 34347339520 scopus 로고    scopus 로고
    • Methods and strategies for analyzing copy number variation using DNA microarrays
    • Carter NP, (2007) Methods and strategies for analyzing copy number variation using DNA microarrays. Nat Genet 39: S16-S21.
    • (2007) Nat Genet , vol.39
    • Carter, N.P.1
  • 3
    • 38449122025 scopus 로고    scopus 로고
    • Copy-number variation in control population cohorts
    • Spec No
    • Pinto D, Marshall C, Feuk L, Scherer SW, (2007) Copy-number variation in control population cohorts. Hum Mol Genet 16 Spec No. 2: R168-R173.
    • (2007) Hum Mol Genet , vol.16 , Issue.2
    • Pinto, D.1    Marshall, C.2    Feuk, L.3    Scherer, S.W.4
  • 4
    • 77950461601 scopus 로고    scopus 로고
    • Origins and functional impact of copy number variation in the human genome
    • Conrad DF, Pinto D, Redon R, Feuk L, Gokcumen O, et al. (2010) Origins and functional impact of copy number variation in the human genome. Nature 464: 704-712.
    • (2010) Nature , vol.464 , pp. 704-712
    • Conrad, D.F.1    Pinto, D.2    Redon, R.3    Feuk, L.4    Gokcumen, O.5
  • 5
    • 43049143055 scopus 로고    scopus 로고
    • Mapping and sequencing of structural variation from eight human genomes
    • Kidd JM, Cooper GM, Donahue WF, Hayden HS, Sampas N, et al. (2008) Mapping and sequencing of structural variation from eight human genomes. Nature 453: 56-64.
    • (2008) Nature , vol.453 , pp. 56-64
    • Kidd, J.M.1    Cooper, G.M.2    Donahue, W.F.3    Hayden, H.S.4    Sampas, N.5
  • 6
    • 35348988679 scopus 로고    scopus 로고
    • Paired-end mapping reveals extensive structural variation in the human genome
    • Korbel JO, Urban AE, Affourtit JP, Godwin B, Grubert F, et al. (2007) Paired-end mapping reveals extensive structural variation in the human genome. Science 318: 420-426.
    • (2007) Science , vol.318 , pp. 420-426
    • Korbel, J.O.1    Urban, A.E.2    Affourtit, J.P.3    Godwin, B.4    Grubert, F.5
  • 7
    • 3242808027 scopus 로고    scopus 로고
    • Large-scale copy number polymorphism in the human genome
    • Sebat J, Lakshmi B, Troge J, Alexander J, Young J, et al. (2004) Large-scale copy number polymorphism in the human genome. Science 305: 525-528.
    • (2004) Science , vol.305 , pp. 525-528
    • Sebat, J.1    Lakshmi, B.2    Troge, J.3    Alexander, J.4    Young, J.5
  • 9
    • 55449120805 scopus 로고    scopus 로고
    • Genetic mapping in human disease
    • Altshuler D, Daly MJ, Lander ES, (2008) Genetic mapping in human disease. Science 322: 881-888.
    • (2008) Science , vol.322 , pp. 881-888
    • Altshuler, D.1    Daly, M.J.2    Lander, E.S.3
  • 10
    • 37549033125 scopus 로고    scopus 로고
    • Psoriasis is associated with increased beta-defensin genomic copy number
    • Hollox EJ, Huffmeier U, Zeeuwen PL, Palla R, Lascorz J, et al. (2008) Psoriasis is associated with increased beta-defensin genomic copy number. Nat Genet 40: 23-25.
    • (2008) Nat Genet , vol.40 , pp. 23-25
    • Hollox, E.J.1    Huffmeier, U.2    Zeeuwen, P.L.3    Palla, R.4    Lascorz, J.5
  • 11
    • 59149098800 scopus 로고    scopus 로고
    • Deletion of the late cornified envelope LCE3B and LCE3C genes as a susceptibility factor for psoriasis
    • de Cid R, Riveira-Munoz E, Zeeuwen PL, Robarge J, Liao W, et al. (2009) Deletion of the late cornified envelope LCE3B and LCE3C genes as a susceptibility factor for psoriasis. Nat Genet 41: 211-215.
    • (2009) Nat Genet , vol.41 , pp. 211-215
    • de Cid, R.1    Riveira-Munoz, E.2    Zeeuwen, P.L.3    Robarge, J.4    Liao, W.5
  • 12
    • 77949542167 scopus 로고    scopus 로고
    • Replication of LCE3C-LCE3B CNV as a Risk Factor for Psoriasis and Analysis of Interaction with Other Genetic Risk Factors
    • Huffmeier U, Bergboer JGM, Becker T, Armour JA, Traupe H, et al. (2010) Replication of LCE3C-LCE3B CNV as a Risk Factor for Psoriasis and Analysis of Interaction with Other Genetic Risk Factors. J Invest Dermatol 130: 979-984.
    • (2010) J Invest Dermatol , vol.130 , pp. 979-984
    • Huffmeier, U.1    Bergboer, J.G.M.2    Becker, T.3    Armour, J.A.4    Traupe, H.5
  • 13
    • 42349095075 scopus 로고    scopus 로고
    • Advances in autism genetics: on the threshold of a new neurobiology
    • Abrahams BS, Geschwind DH, (2008) Advances in autism genetics: on the threshold of a new neurobiology. Nat Rev Genet 9: 341-355.
    • (2008) Nat Rev Genet , vol.9 , pp. 341-355
    • Abrahams, B.S.1    Geschwind, D.H.2
  • 14
    • 47949100426 scopus 로고    scopus 로고
    • Genetic variants of the copy number polymorphic beta-defensin locus are associated with sporadic prostate cancer
    • Huse K, Taudien S, Groth M, Rosenstiel P, Szafranski K, et al. (2008) Genetic variants of the copy number polymorphic beta-defensin locus are associated with sporadic prostate cancer. Tumour Biol 29: 83-92.
    • (2008) Tumour Biol , vol.29 , pp. 83-92
    • Huse, K.1    Taudien, S.2    Groth, M.3    Rosenstiel, P.4    Szafranski, K.5
  • 16
    • 42349088634 scopus 로고    scopus 로고
    • Rare structural variants disrupt multiple genes in neurodevelopmental pathways in schizophrenia
    • Walsh T, McClellan JM, McCarthy SE, Addington AM, Pierce SB, et al. (2008) Rare structural variants disrupt multiple genes in neurodevelopmental pathways in schizophrenia. Science 320: 539-543.
    • (2008) Science , vol.320 , pp. 539-543
    • Walsh, T.1    McClellan, J.M.2    McCarthy, S.E.3    Addington, A.M.4    Pierce, S.B.5
  • 17
    • 46249093584 scopus 로고    scopus 로고
    • Strong association of de novo copy number mutations with sporadic schizophrenia
    • Xu B, Roos JL, Levy S, van Rensburg EJ, Gogos JA, et al. (2008) Strong association of de novo copy number mutations with sporadic schizophrenia. Nat Genet 40: 880-885.
    • (2008) Nat Genet , vol.40 , pp. 880-885
    • Xu, B.1    Roos, J.L.2    Levy, S.3    van Rensburg, E.J.4    Gogos, J.A.5
  • 18
    • 32844460938 scopus 로고    scopus 로고
    • Copy number polymorphism in Fcgr3 predisposes to glomerulonephritis in rats and humans
    • Aitman TJ, Dong R, Vyse TJ, Norsworthy PJ, Johnson MD, et al. (2006) Copy number polymorphism in Fcgr3 predisposes to glomerulonephritis in rats and humans. Nature 439: 851-855.
    • (2006) Nature , vol.439 , pp. 851-855
    • Aitman, T.J.1    Dong, R.2    Vyse, T.J.3    Norsworthy, P.J.4    Johnson, M.D.5
  • 19
    • 34249815834 scopus 로고    scopus 로고
    • FCGR3B copy number variation is associated with susceptibility to systemic, but not organ-specific, autoimmunity
    • Fanciulli M, Norsworthy PJ, Petretto E, Dong R, Harper L, et al. (2007) FCGR3B copy number variation is associated with susceptibility to systemic, but not organ-specific, autoimmunity. Nat Genet 39: 721-723.
    • (2007) Nat Genet , vol.39 , pp. 721-723
    • Fanciulli, M.1    Norsworthy, P.J.2    Petretto, E.3    Dong, R.4    Harper, L.5
  • 20
    • 34250841166 scopus 로고    scopus 로고
    • Gene copy-number variation and associated polymorphisms of complement component C4 in human systemic lupus erythematosus (SLE): low copy number is a risk factor for and high copy number is a protective factor against SLE susceptibility in European Americans
    • Yang Y, Chung EK, Wu YL, Savelli SL, Nagaraja HN, et al. (2007) Gene copy-number variation and associated polymorphisms of complement component C4 in human systemic lupus erythematosus (SLE): low copy number is a risk factor for and high copy number is a protective factor against SLE susceptibility in European Americans. Am J Hum Genet 80: 1037-1054.
    • (2007) Am J Hum Genet , vol.80 , pp. 1037-1054
    • Yang, Y.1    Chung, E.K.2    Wu, Y.L.3    Savelli, S.L.4    Nagaraja, H.N.5
  • 23
    • 77953232121 scopus 로고    scopus 로고
    • Mechanisms for Nonrecurrent Genomic Rearrangements Associated with CMT1A or HNPP: Rare CNVs as a Cause for Missing Heritability
    • Zhang F, Seeman P, Liu P, Gonzaga-Jauregui C, Towne CF, et al. (2010) Mechanisms for Nonrecurrent Genomic Rearrangements Associated with CMT1A or HNPP: Rare CNVs as a Cause for Missing Heritability. The American Journal of Human Genetics 86: 892-903.
    • (2010) The American Journal of Human Genetics , vol.86 , pp. 892-903
    • Zhang, F.1    Seeman, P.2    Liu, P.3    Gonzaga-Jauregui, C.4    Towne, C.F.5
  • 25
    • 61849115785 scopus 로고    scopus 로고
    • Copy number variation in the human genome and its implication in autoimmunity
    • Schaschl H, Aitman TJ, Vyse TJ, (2009) Copy number variation in the human genome and its implication in autoimmunity. Clin Exp Immunol 156: 12-16.
    • (2009) Clin Exp Immunol , vol.156 , pp. 12-16
    • Schaschl, H.1    Aitman, T.J.2    Vyse, T.J.3
  • 26
    • 26444577882 scopus 로고    scopus 로고
    • Copy number polymorphism and expression level variation of the human alpha-defensin genes DEFA1 and DEFA3
    • Aldred PM, Hollox EJ, Armour JA, (2005) Copy number polymorphism and expression level variation of the human alpha-defensin genes DEFA1 and DEFA3. Hum Mol Genet 14: 2045-2052.
    • (2005) Hum Mol Genet , vol.14 , pp. 2045-2052
    • Aldred, P.M.1    Hollox, E.J.2    Armour, J.A.3
  • 27
    • 0032815762 scopus 로고    scopus 로고
    • A 450-kb contig of defensin genes on human chromosome 8p23
    • Linzmeier R, Ho CH, Hoang BV, Ganz T, (1999) A 450-kb contig of defensin genes on human chromosome 8p23. Gene 233: 205-211.
    • (1999) Gene , vol.233 , pp. 205-211
    • Linzmeier, R.1    Ho, C.H.2    Hoang, B.V.3    Ganz, T.4
  • 28
    • 0042387792 scopus 로고    scopus 로고
    • Extensive normal copy number variation of a beta-defensin antimicrobial-gene cluster
    • Hollox EJ, Armour JA, Barber JC, (2003) Extensive normal copy number variation of a beta-defensin antimicrobial-gene cluster. Am J Hum Genet 73: 591-600.
    • (2003) Am J Hum Genet , vol.73 , pp. 591-600
    • Hollox, E.J.1    Armour, J.A.2    Barber, J.C.3
  • 29
    • 0141799911 scopus 로고    scopus 로고
    • Defensins: antimicrobial peptides of innate immunity
    • Ganz T, (2003) Defensins: antimicrobial peptides of innate immunity. Nat Rev Immunol 3: 710-720.
    • (2003) Nat Rev Immunol , vol.3 , pp. 710-720
    • Ganz, T.1
  • 30
    • 0030038197 scopus 로고    scopus 로고
    • Identification of defensin-1, defensin-2, and CAP37/azurocidin as T-cell chemoattractant proteins released from interleukin-8-stimulated neutrophils
    • Chertov O, Michiel DF, Xu L, Wang JM, Tani K, et al. (1996) Identification of defensin-1, defensin-2, and CAP37/azurocidin as T-cell chemoattractant proteins released from interleukin-8-stimulated neutrophils. J Biol Chem 271: 2935-2940.
    • (1996) J Biol Chem , vol.271 , pp. 2935-2940
    • Chertov, O.1    Michiel, D.F.2    Xu, L.3    Wang, J.M.4    Tani, K.5
  • 31
    • 0033569408 scopus 로고    scopus 로고
    • Beta-Defensins: Linking Innate and Adaptive Immunity Through Dendritic and T Cell CCR6
    • Yang D, Chertov O, Bykovskaia SN, Chen Q, Buffo MJ, et al. (1999) Beta-Defensins: Linking Innate and Adaptive Immunity Through Dendritic and T Cell CCR6. Science 286: 525-528.
    • (1999) Science , vol.286 , pp. 525-528
    • Yang, D.1    Chertov, O.2    Bykovskaia, S.N.3    Chen, Q.4    Buffo, M.J.5
  • 32
    • 61349169039 scopus 로고    scopus 로고
    • AMPed up immunity: how antimicrobial peptides have multiple roles in immune defense
    • Lai Y, Gallo RL, (2009) AMPed up immunity: how antimicrobial peptides have multiple roles in immune defense. Trends Immunol 30: 131-141.
    • (2009) Trends Immunol , vol.30 , pp. 131-141
    • Lai, Y.1    Gallo, R.L.2
  • 33
    • 22544457464 scopus 로고    scopus 로고
    • The human beta-defensins (-1, -2, -3, -4) and cathelicidin LL-37 induce IL-18 secretion through p38 and ERK MAPK activation in primary human keratinocytes
    • Niyonsaba F, Ushio H, Nagaoka I, Okamura K, Ogawa H, (2005) The human beta-defensins (-1,-2,-3,-4) and cathelicidin LL-37 induce IL-18 secretion through p38 and ERK MAPK activation in primary human keratinocytes. J Immunol 175: 1776-1784.
    • (2005) J Immunol , vol.175 , pp. 1776-1784
    • Niyonsaba, F.1    Ushio, H.2    Nagaoka, I.3    Okamura, K.4    Ogawa, H.5
  • 34
    • 33645757768 scopus 로고    scopus 로고
    • Human beta-defensin 2 induces a vigorous cytokine response in peripheral blood mononuclear cells
    • Boniotto M, Jordan WJ, Eskdale J, Tossi A, Antcheva N, et al. (2006) Human beta-defensin 2 induces a vigorous cytokine response in peripheral blood mononuclear cells. Antimicrob Agents Chemother 206 50: 1433-1441.
    • (2006) Antimicrob Agents Chemother 206 , vol.50 , pp. 1433-1441
    • Boniotto, M.1    Jordan, W.J.2    Eskdale, J.3    Tossi, A.4    Antcheva, N.5
  • 35
    • 77956209435 scopus 로고    scopus 로고
    • An antimicrobial peptide regulates tumor-associated macrophage trafficking via the chemokine receptor CCR2, a model for tumorigenesis
    • Jin G, Kawsar HI, Hirsch SA, Zeng C, Jia X, et al. (2010) An antimicrobial peptide regulates tumor-associated macrophage trafficking via the chemokine receptor CCR2, a model for tumorigenesis. PLoS One 5: e10993-.
    • (2010) PLoS One , vol.5
    • Jin, G.1    Kawsar, H.I.2    Hirsch, S.A.3    Zeng, C.4    Jia, X.5
  • 36
    • 36749008499 scopus 로고    scopus 로고
    • A β-defensin mutation causes black coat color in domestic dogs
    • Candille SI, Kaelin CB, Cattanach BM, Yu B, Thompson DA, et al. (2007) A β-defensin mutation causes black coat color in domestic dogs. Science 318: 1418-1423.
    • (2007) Science , vol.318 , pp. 1418-1423
    • Candille, S.I.1    Kaelin, C.B.2    Cattanach, B.M.3    Yu, B.4    Thompson, D.A.5
  • 37
    • 77951046523 scopus 로고    scopus 로고
    • Human beta-defensin 3 has immunosuppressive activity in vitro and in vivo
    • Semple F, Webb S, Li HN, Patel HB, Perretti M, et al. (2010) Human beta-defensin 3 has immunosuppressive activity in vitro and in vivo. Eur J Immunol 40: 1073-1078.
    • (2010) Eur J Immunol , vol.40 , pp. 1073-1078
    • Semple, F.1    Webb, S.2    Li, H.N.3    Patel, H.B.4    Perretti, M.5
  • 39
    • 62549137023 scopus 로고    scopus 로고
    • Copy number variation of beta-defensins and relevance to disease
    • Hollox EJ, (2008) Copy number variation of beta-defensins and relevance to disease. Cytogenet Genome Res 123: 148-155.
    • (2008) Cytogenet Genome Res , vol.123 , pp. 148-155
    • Hollox, E.J.1
  • 40
    • 29144457296 scopus 로고    scopus 로고
    • Human defensin gene copy number polymorphisms: comprehensive analysis of independent variation in alpha- and beta-defensin regions at 8p22-p23
    • Linzmeier RM, Ganz T, (2005) Human defensin gene copy number polymorphisms: comprehensive analysis of independent variation in alpha- and beta-defensin regions at 8p22-p23. Genomics 86: 423-430.
    • (2005) Genomics , vol.86 , pp. 423-430
    • Linzmeier, R.M.1    Ganz, T.2
  • 41
    • 55549113578 scopus 로고    scopus 로고
    • Defensins and the dynamic genome: What we can learn from structural variation at human chromosome band 8p23.1
    • Hollox EJ, Barber JC, Brookes AJ, Barber JC, (2008) Defensins and the dynamic genome: What we can learn from structural variation at human chromosome band 8p23.1. Genome Res 18: 1686-1697.
    • (2008) Genome Res , vol.18 , pp. 1686-1697
    • Hollox, E.J.1    Barber, J.C.2    Brookes, A.J.3    Barber, J.C.4
  • 42
    • 47949093301 scopus 로고    scopus 로고
    • High-resolution mapping of the 8p23.1 beta-defensin cluster reveals strictly concordant copy number variation of all genes
    • Groth M, Szafranski K, Taudien S, Huse K, Mueller O, et al. (2008) High-resolution mapping of the 8p23.1 beta-defensin cluster reveals strictly concordant copy number variation of all genes. Hum Mutat 29: 1247-1254.
    • (2008) Hum Mutat , vol.29 , pp. 1247-1254
    • Groth, M.1    Szafranski, K.2    Taudien, S.3    Huse, K.4    Mueller, O.5
  • 44
    • 33748558056 scopus 로고    scopus 로고
    • A chromosome 8 gene-cluster polymorphism with low human beta-defensin 2 gene copy number predisposes to Crohn disease of the colon
    • Fellermann K, Stange DE, Schaeffeler E, Schmazl H, Wehkamp J, et al. (2006) A chromosome 8 gene-cluster polymorphism with low human beta-defensin 2 gene copy number predisposes to Crohn disease of the colon. Am J Hum Genet 79: 439-448.
    • (2006) Am J Hum Genet , vol.79 , pp. 439-448
    • Fellermann, K.1    Stange, D.E.2    Schaeffeler, E.3    Schmazl, H.4    Wehkamp, J.5
  • 45
    • 59749090025 scopus 로고    scopus 로고
    • Sample degradation leads to false-positive copy number variation calls in multiplex real-time polymerase chain reaction assays
    • Cukier HN, Pericak-Vance MA, Gilbert JR, Hedges DJ, (2009) Sample degradation leads to false-positive copy number variation calls in multiplex real-time polymerase chain reaction assays. Anal Biochem 386: 288-290.
    • (2009) Anal Biochem , vol.386 , pp. 288-290
    • Cukier, H.N.1    Pericak-Vance, M.A.2    Gilbert, J.R.3    Hedges, D.J.4
  • 46
    • 70350455320 scopus 로고    scopus 로고
    • Experimental aspects of copy number variant assays at CCL3L1
    • Field SF, Howson JM, Maier LM, Walker S, Walker NM, et al. (2009) Experimental aspects of copy number variant assays at CCL3L1. Nat Med 15: 1115-1117.
    • (2009) Nat Med , vol.15 , pp. 1115-1117
    • Field, S.F.1    Howson, J.M.2    Maier, L.M.3    Walker, S.4    Walker, N.M.5
  • 47
    • 76349116970 scopus 로고    scopus 로고
    • Beta-defensins and Crohn's disease: confusion from counting copies
    • Hollox EJ, (2010) Beta-defensins and Crohn's disease: confusion from counting copies. Am J Gastroenterol 105: 360-362.
    • (2010) Am J Gastroenterol , vol.105 , pp. 360-362
    • Hollox, E.J.1
  • 48
    • 33846978695 scopus 로고    scopus 로고
    • Relative impact of nucleotide and copy number variation on gene expression phenotypes
    • Stranger BE, Forrest MS, Dunning M, Ingle CE, Beazley C, et al. (2007) Relative impact of nucleotide and copy number variation on gene expression phenotypes. Science 315: 848-853.
    • (2007) Science , vol.315 , pp. 848-853
    • Stranger, B.E.1    Forrest, M.S.2    Dunning, M.3    Ingle, C.E.4    Beazley, C.5
  • 49
    • 77956342285 scopus 로고    scopus 로고
    • Both copy number and sequence variations affect expression of human DEFB4
    • Groth M, Wiegand C, Szafranski K, Huse K, Kramer M, et al. (2010) Both copy number and sequence variations affect expression of human DEFB4. Genes Immun pp. 1158-466.
    • (2010) Genes Immun , pp. 1158-1466
    • Groth, M.1    Wiegand, C.2    Szafranski, K.3    Huse, K.4    Kramer, M.5
  • 50
    • 33847390726 scopus 로고    scopus 로고
    • Accurate, high-throughput typing of copy number variation using paralogue ratios from dispersed repeats
    • Armour JA, Palla R, Zeeuwen PL, den Heijer M, Schalkwijk J, et al. (2007) Accurate, high-throughput typing of copy number variation using paralogue ratios from dispersed repeats. Nucleic Acids Res 35: e19.
    • (2007) Nucleic Acids Res , vol.35
    • Armour, J.A.1    Palla, R.2    Zeeuwen, P.L.3    den Heijer, M.4    Schalkwijk, J.5
  • 52
    • 58849117701 scopus 로고    scopus 로고
    • Allelic recombination between distinct genomic locations generates copy number diversity in human β-defensins
    • Bakar SA, Hollox EJ, Armour JAL, (2009) Allelic recombination between distinct genomic locations generates copy number diversity in human β-defensins. Proceedings of the National Academy of Sciences 106: 853-858.
    • (2009) Proceedings of the National Academy of Sciences , vol.106 , pp. 853-858
    • Bakar, S.A.1    Hollox, E.J.2    Armour, J.A.L.3
  • 53
    • 78649479154 scopus 로고    scopus 로고
    • Measurement methods and accuracy in copy number variation: failure to replicate association of low beta-defensin copy number with colonic Crohn's disease
    • Aldous MC, Abu Bakar S, Prescott NJ, Palla R, Soo K, et al. (2010) Measurement methods and accuracy in copy number variation: failure to replicate association of low beta-defensin copy number with colonic Crohn's disease. Hum Mol Genet 19: 4930-4938.
    • (2010) Hum Mol Genet , vol.19 , pp. 4930-4938
    • Aldous, M.C.1    Abu Bakar, S.2    Prescott, N.J.3    Palla, R.4    Soo, K.5
  • 54
    • 61649092570 scopus 로고    scopus 로고
    • An integrated approach for measuring copy number variation at the FCGR3 (CD16) locus
    • Hollox EJ, Detering JC, Dehnugara T, (2009) An integrated approach for measuring copy number variation at the FCGR3 (CD16) locus. Hum Mutat 30: 477-484.
    • (2009) Hum Mutat , vol.30 , pp. 477-484
    • Hollox, E.J.1    Detering, J.C.2    Dehnugara, T.3
  • 55
    • 77953363607 scopus 로고    scopus 로고
    • Comparison of multiplex ligation-dependent probe amplification and real-time PCR accuracy for gene copy number quantification using the beta-defensin locus
    • Perne A, Zhang X, Lehmann L, Groth M, Stuber F, et al. (2009) Comparison of multiplex ligation-dependent probe amplification and real-time PCR accuracy for gene copy number quantification using the beta-defensin locus. Biotechniques 47: 1023-1028.
    • (2009) Biotechniques , vol.47 , pp. 1023-1028
    • Perne, A.1    Zhang, X.2    Lehmann, L.3    Groth, M.4    Stuber, F.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.