Diabetic retinopathy is associated with subclinical atherosclerosis in newly diagnosed type 2 diabetes mellitus

Diabetes Research and Clinical Practice

Volumn 91, Issue 2, 2011, Pages 253-259

  Son, Jang Won ^a   Jang, Eun Hee ^a   Kim, Mee Kyoung ^a   Kim, In Tae ^a   Roh, Young Jung ^a   Baek, Ki Hyun ^a   Song, Ki Ho ^a   Yoon, Kun Ho ^a   Cha, Bong Yun ^a   Lee, Kwang Woo ^a   Son, Ho Young ^a   Kwon, Hyuk Sang ^a  

^a The Catholic University of Korea   (South Korea)

Author keywords

Atherosclerosis; Carotid intima media thickness; Diabetic retinopathy

Indexed keywords

HEMOGLOBIN A1C; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL;

ADULT; AGE; ARTERIAL WALL THICKNESS; ARTICLE; ATHEROSCLEROSIS; BODY MASS; CARDIOVASCULAR RISK; CAROTID ARTERY; CIGARETTE SMOKING; CONTROLLED STUDY; DIABETIC MICROANGIOPATHY; DIABETIC NEPHROPATHY; DIABETIC RETINOPATHY; DISEASE ASSOCIATION; FEMALE; HUMAN; HYPERTENSION; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; RISK ASSESSMENT; SEX DIFFERENCE;

ADULT; AGED; ATHEROSCLEROSIS; DIABETES MELLITUS, TYPE 2; DIABETIC RETINOPATHY; FEMALE; HUMANS; MALE; MIDDLE AGED; RISK FACTORS; TUNICA INTIMA; TUNICA MEDIA;

EID: 79952040952     PISSN: 01688227     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.diabres.2010.11.005     Document Type: Article

References (32)

1. Kharlip J., Naglieri R., Mitchell B.D., Ryan K.A., Donner T.W. Screening for silent coronary heart disease in type 2 diabetes: clinical application of American Diabetes Association guidelines. Diabetes Care 2006, 29:692-694.
2. Bax J.J., Young L.H., Frye R.L., Bonow R.O., Steinberg H.O., Barrett E.J. Screening for coronary artery disease in patients with diabetes. Diabetes Care 2007, 30:2729-2736.
3. Haffner S.M., Stern M.P., Hazuda H.P., Mitchell B.D., Patterson J.K. Cardiovascular risk factors in confirmed prediabetic individuals. Does the clock for coronary heart disease start ticking before the onset of clinical diabetes?. JAMA 1990, 263:2893-2898.
4. Hackam D.G., Anand S.S. Emerging risk factors for atherosclerotic vascular disease: a critical review of the evidence. JAMA 2003, 290:932-940.
5. Hodis H.N., Mack W.J., LaBree L., Selzer R.H., Liu C.R., Liu C.H., et al. The role of carotid arterial intima-media thickness in predicting clinical coronary events. Ann Int Med 1998, 128:262-269.
6. Stern M.P. Diabetes and cardiovascular disease. The common soil hypothesis. Diabetes 1995, 44:369-374.
7. Hiller R., Sperduto R.D., Podgor M.J., Ferris F.L., Wilson P.W. Diabetic retinopathy and cardiovascular disease in type II diabetics The Framingham Heart Study and the Framingham Eye Study. Am J Epidemiol 1988, 128:402-409.
8. Targher G., Bertolini L., Tessari R., Zenari L., Arcaro G. Retinopathy predicts future cardiovascular events among type 2 diabetic patients: the Valpolicella Heart Diabetes Study. Diabetes Care 2006, 29:1178.
9. Juutilainen A., Lehto S., Rönnemaa T., Pyörälà K., Laakso M. Retinopathy predicts cardiovascular mortality in type 2 diabetic men and women. Diabetes Care 2007, 30:292-299.
10. Dinneen S.F., Gerstein H.C. The association of microalbuminuria and mortality in non-insulin-dependent diabetes mellitus. A systematic overview of the literature. Arch Int Med 1997, 157:1413-1418.
11. Yokoyama H., Yokota Y., Tada J., Kanno S. Diabetic neuropathy is closely associated with arterial stiffening and thickness in Type 2 diabetes. Diabet Med 2007, 24:1329-1335.
12. Miettinen H., Haffner S.M., Lehto S., Rönnemaa T., Pyörälà K., Laakso M. Retinopathy predicts coronary heart disease events in NIDDM patients. Diabetes Care 1996, 19:1445-1448.
13. Faglia E., Favales F., Calia P., Paleari F., Segalini G., Gamba P.L., et al. Cardiac events in 735 type 2 diabetic patients who underwent screening for unknown asymptomatic coronary heart disease: 5-year follow-up report from the Milan Study on Atherosclerosis and Diabetes (MiSAD). Diabetes Care 2002, 25:2032-2036.
14. Targher G., Bertolini L., Zenari L., Lippi G., Pichiri I., Zoppini G., et al. Diabetic retinopathy is associated with an increased incidence of cardiovascular events in Type 2 diabetic patients. Diabet Med 2008, 25:45-50.
15. Stratton I.M., Adler A.I., Neil H.A., Matthews D.R., Manley S.E., Cull C.A., et al. Association of glycaemia with macrovascular and microvascular complications of type 2 diabetes (UKPDS 35): prospective observational study. BMJ 2000, 321:405-412.
16. Barzilay J.I., Spiekerman C.F., Kuller L.H., Burke G.L., Bittner V., Gottdiener J.S., et al. Prevalence of clinical and isolated subclinical cardiovascular disease in older adults with glucose disorders: the Cardiovascular Health Study. Diabetes Care 2001, 24:1233-1239.
17. Wagenknecht L.E., D'Agostino R.B., Haffner S.M., Savage P.J., Rewers M. Impaired glucose tolerance, type 2 diabetes, and carotid wall thickness: the Insulin Resistance Atherosclerosis Study. Diabetes Care 1998, 21:1812-1818.
18. Temelkova-Kurktschiev T.S., Koehler C., Leonhardt W., Schaper F., Henkel E., Siegert G., et al. Increased intimal-medial thickness in newly detected type 2 diabetes: risk factors. Diabetes Care 1999, 22:333-338.
19. Lorenz M.W., Markus H.S., Bots M.L., Rosvall M., Sitzer M. Prediction of clinical cardiovascular events with carotid intima-media thickness: a systematic review and meta-analysis. Circulation 2007, 115:459-467.
20. Bernard S., Serusclat A., Targe F., Charrière S., Roth O., Beaune J., et al. Incremental predictive value of carotid ultrasonography in the assessment of coronary risk in a cohort of asymptomatic type 2 diabetic subjects. Diabetes Care 2005, 28:1158-1162.
21. Feldman E.L., Stevens M.J., Thomas P.K., Brown M.B., Canal N., Greene D.A. A practical two-step quantitative clinical and electrophysiological assessment for the diagnosis and staging of diabetic neuropathy. Diabetes Care 1994, 17:1281-1289.
22. Mancia G., De Backer G., Dominiczak A., Cifkova R., Fagard R., Germano G., et al. 2007 Guidelines for the management of arterial hypertension: The Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC). Eur Heart J 2007, 28:1462-1536.
23. Group UKPDS. The UKPDS Risk Engine: a model for the risk of coronary heart disease in type 2 diabetes (UKPDS 56). ClinSci 2001, 101:671-679.
24. Klein R., Marino E.K., Kuller L.H., Polak J.F., Tracy R.P., Gottdiener J.S., et al. The relation of atherosclerotic cardiovascular disease to retinopathy in people with diabetes in the Cardiovascular Health Study. Br J Ophthalmol 2002, 86:84-90.
25. Norgaz T., Hobikoglu G., Aksu H., Guveli A., Aksoy S., Ozer O., et al. Retinopathy is related to the angiographically detected severity and extent of coronary artery disease in patients with type 2 diabetes mellitus. Int HeartJ 2005, 46:639-646.
26. Rema M., Mohan V., Deepa R., Ravikumar R. Association of carotid intima-media thickness and arterial stiffness with diabetic retinopathy: the Chennai Urban Rural Epidemiology Study (CURES-2). Diabetes Care 2004, 27:1962-1967.
27. Cheung N., Wang J.J., Klein R., Couper D.J., Sharrett A.R., Wong T.Y. Diabetic retinopathy and the risk of coronary heart disease: the Atherosclerosis Risk in Communities Study. Diabetes Care 2007, 30:1742-1746.
28. Klein B.E., Klein R., McBride P.E., Cruickshanks K.J., Palta M., Knudtson M.D., et al. Cardiovascular disease, mortality, and retinal microvascular characteristics in type 1 diabetes: Wisconsin Epidemiologic Study of Diabetic Retinopathy. Arch Int Med 2004, 64:1917-1924.
29. Gimeno-Orna J.A., Faure-Nogueras E., Castro-Alonso F.J., Boned-Juliani B. Ability of retinopathy to predict cardiovascular disease in patients with type 2 diabetes mellitus. Am J Cardiol 2009, 103:1364-1367.
30. Malecki M.T., Osmenda G., Walus-Miarka M., Skupien J., Cyganek K., Mirkiewicz-Sieradzka B., et al. Retinopathy in type 2 diabetes mellitus is associated with increased intima-media thickness and endothelial dysfunction. Eur J Clin Invest 2008, 38:925-930.
31. Sigurdardottir V., Fagerberg B., Hulthe J. Preclinical atherosclerosis and inflammation in 61-year-old men with newly diagnosed diabetes and established diabetes. Diabetes Care 2004, 27:880-884.
32. Fong D.S., Aiello L., Gardner T.W., King G.L., Blankenship G., Cavallerano J.D., et al. Diabetic retinopathy. Diabetes Care 2003, 26(Suppl. 1):s99-s102.