Point-of-care device for quantification of bilirubin in skin tissue

IEEE Transactions on Biomedical Engineering

Volumn 58, Issue 3 PART 2, 2011, Pages 777-780

  Alla, Suresh K ^a   Huddle, Adam ^a   Butler, Joshua D ^a   Bowman, Peggy S ^a   Clark, Joseph F ^b   Beyette Jr , Fred R ^a  

^a 705 Engineering Research Center   (United States)

^b UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

Author keywords

Bilirubin quantification; hyperbilirubinemia; Jaundice; skin reflectance

Indexed keywords

ANIMAL MODEL; BILIRUBIN QUANTIFICATION; BLOOD STREAMS; DIFFUSE REFLECTANCE MEASUREMENTS; DIFFUSE REFLECTANCE SPECTROSCOPY; HUMAN VOLUNTEERS; HYPERBILIRUBINEMIA; JAUNDICE; MEDICAL CONDITIONS; NONDESTRUCTIVE METHODS; NORMAL SKIN; POINT OF CARE; POINT-OF-CARE SYSTEMS; REAL-TIME ASSESSMENT; REFLECTANCE SPECTRUM; SIGNAL PROCESSING ALGORITHMS; SKIN TISSUE; SPECTRAL DATABASE; SPECTRAL MEASUREMENT; STEADY STATE;

CHROMOPHORES; DATABASE SYSTEMS; OPTICAL SYSTEMS; SIGNAL PROCESSING; SPECTROSCOPY; TISSUE;

REFLECTION;

BILIRUBIN; HEMOGLOBIN;

ALGORITHM; ANALYTICAL EQUIPMENT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD CHEMISTRY; CHROMATOPHORE; CLINICAL FEATURE; CONTROLLED STUDY; DATA BASE; DIFFUSE REFLECTANCE SPECTROSCOPY; EQUIPMENT DESIGN; FIBER OPTICS; HEMATOCRIT; HOSPITAL INFORMATION SYSTEM; HUMAN; HUMAN TISSUE; MEDICAL INSTRUMENTATION; NEWBORN JAUNDICE; NON INVASIVE PROCEDURE; NONHUMAN; OPTICAL INSTRUMENTATION; POINT OF CARE DEVICE; POINT OF CARE TESTING; SIGNAL PROCESSING; SKIN EXAMINATION; SPECTROMETER; SWINE; VOLUNTEER;

ALGORITHMS; ANIMALS; BILIRUBIN; BLOOD GAS MONITORING, TRANSCUTANEOUS; DISEASE MODELS, ANIMAL; HUMANS; JAUNDICE; POINT-OF-CARE SYSTEMS; SIGNAL PROCESSING, COMPUTER-ASSISTED; SKIN; SPECTRUM ANALYSIS; SWINE;

EID: 79952031587     PISSN: 00189294     EISSN: None     Source Type: Journal    
DOI: 10.1109/TBME.2010.2093132     Document Type: Article

References (8)

1. S. N. el-Beshbishi, K. E. Shattuck, A. A. Mohammad, and J. R. Petersen, "Hyperbilirubinemia and transcutaneous bilirubinometry," Clin. Chem., vol. 55, no. 7, pp. 1280-1287, Jul. 2009.
2. C. E. Ahlfors, "Bilirubin-albumin binding and free bilirubin," J. Perinatol., vol. 21, pp. S40-S42, Dec. 2001.
3. G. Zonios, Lev T. Perelman, V. Backman, R. Manoharan, M. Fitzmaurice, J. Van Dam, and M. S. Feld, "Diffuse reflectance spectroscopy of human adenomatous colon polyps in vivo," Appl. Opt., vol. 38, pp. 6628-6637, 1999.
4. L. F. A. Douven and G. W. Lucassen, "Retrieval of optical properties of skin from measurement and modelling the diffuse reflectance," in Proc. SPIE, 2000, vol. 3914, pp. 312-323.
5. G. Zonios andA.Dimou, "Modeling diffuse reflectance from semi-infinite turbid media: Application to the study of skin optical properties," Opt. Exp., vol. 14, pp. 8661-8674, 2006.
6. [Online]. Available: http://tomopt.com/tomlab/products/sol/solvers/ NLSSOL.php (Accessed: Jan. 22, 2010).
7. S. K. Alla, J. F. Clark, and F. R. Beyette, "Signal processing system to extract serum bilirubin concentration from diffuse reflectance spectrum of human skin," in Proc. IEEE Ann. Int. Conf. Eng. Med. Biol. Soc. (EMBC), Sep. 2009, pp. 1290-1293.
8. T. Dimitrova, L. Georgieva, C. Pattichis, and M. Neofytou, "Qualitative visual image analysis of bruise age determination: A Survey," in Proc. IEEE Ann. Int. Conf. Eng. Med. Biol. Soc. (EMBS), 2006, pp. 4840-4843.