Bridgehead nitrogen heterocyclic systems: Facile synthesis, bioactivity of some newer derivatives of 1-substituted benzylidene hydrazino tetrazolo [1, 5-a] quinoxalines

International Journal of Pharmaceutical Sciences Review and Research

Volumn 2, Issue 2, 2010, Pages 24-28

  Umarani, N ^a   Ilango, K ^a  

^a SRM INSTITUTE OF SCIENCE AND TECHNOLOGY   (India)

Author keywords

Scaffold; Spectral studies; Synthetic strategy; Tetrazolo quinoxalines

Indexed keywords

1 [(2 DIMETHYLAMINOBENZYLIDENE)HYDRAZINO 2 TETRAZOLO[1,5 A]QUINOXALINE]; 1 [(2 HYDROXYBENZYLIDENE)HYDRAZINO 2 TETRAZOLO[1,5 A]QUINOXALINE]; 1 [(3,4,5 TRIMETHOXYBENZYLIDENE)HYDRAZINO 2 TETRAZOLO[1,5 A]QUINOXALINE]; 1 [(4 CHLOROBENZYLIDENE)HYDRAZINO 2 TETRAZOLO[1,5 A]QUINOXALINE]; 1 [(4 NITROBENZYLIDENE)HYDRAZINO 2 TETRAZOLO[1,5 A]QUINOXALINE]; 1 SUBSTITUTED BENZYLIDENEHYDRAZINO 2 TETRAZOLO[1,5 A]QUINOXALINE; 2,3 QUINOXALINEDIONE DERIVATIVE; GRISEOFULVIN; HETEROCYCLIC NITRO COMPOUND; HYDRAZIDE; OFLOXACIN; OXALIC ACID; QUINOXALINE DERIVATIVE; SODIUM AZIDE; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ANTIFUNGAL ACTIVITY; ARTICLE; ASPERGILLUS NIGER; CANDIDA ALBICANS; CHLORINATION; CONTROLLED STUDY; CYCLIZATION; DRUG STRUCTURE; DRUG SYNTHESIS; ESCHERICHIA COLI; INFRARED SPECTROSCOPY; KLEBSIELLA PNEUMONIAE; MASS SPECTROMETRY; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; PSEUDOMONAS AERUGINOSA; STAPHYLOCOCCUS AUREUS;

EID: 79952031480     PISSN: None     EISSN: 0976044X     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. Fonsca, T.; Giganta, B.; Marques, M.M.; Gilchrist, T.L.; Clercq, E.D. Bio-org Med Chem. Lett. 2004, 12, 103.
2. Habib, N.S.; EL-Hawash, S.A. Pharmazie. 1997, 57, 594.
3. Sarger, R.; Howard, H.R.; Browne, R.G.; Lebel, L.A.; Seymour, P.A.; Koe, B.K. J. Med. Chem. 1990, 33, 2240.
4. Jaso, A.; Zarranz, B.; Aladana, I.; Monge, A. Eur.J. Med. Chem. 2003, 38, 791.
5. Glombik, H.; Ger Offen, D.E. Chem. Abstr. 1990, 113, 97626W.
6. Treuncr, U.D.; Squibb, E.R. Chem. Abstr. 1978, 88 62421.
7. Mishra, B. Indian. J. Chem. 1987, 27B, 576.
8. Love, B.; Musser, J.H.; Brown, R.D.; Jones.H.; Kahen.R.; Huang.C.; Kanduwala.A.; Goldman.P.S.; Leibowitz. J. Med. Chem. 1985, 28, 363.
9. Sanna, P.; Carta, M.; LorigaZanetti, S.; Sechi. IL Farmaco. 1999, 54, 161.
10. Sridhar, D.R.; Jogibhukta, M.; Joshi, P.P.; Reddy, P.G. Indian J. Chem. 1984, 20B, 2013.
11. Bigge, C.F.; Malone, T.C.; Boxer, P.A.; Nelson, C.D.; Ortwine, D.F.; Sehelkun, R.M.; Retz, D.M.; Lescosky, L.G.; Borosky, S.A.; Vartanian, M.G.; Schwarz, R.T.; Camphell, G.W.; Robichaud, L.J.; Watjen, F. J. Med. Chem. 1995, 38, 3720.
12. Reddy Sastry, C.V.; Narayanan, G.K.A.S.S.; Krishnan, V.S.H.; Vemana, K.; Sridhar, D.R.; Singh, P.P.; Jurnarkar, A.Y.; Indian J. Chem. 1991, 30B, 953.
13. Gilchrist, T.L. Heterocyclic Chemistry, Longman Scientific and Technical Publisher, U.K, 1984, 187.
14. Wermuth, C.G. The Practice of Medicinal Chemistry, Academic Press, New York, 1996, 215.
15. Bory, P.R.; Reitz, D.B.; Collins, J.D.; Chamberlain, T.S.; Olins, G.M.; Smita, G.J.; McGraw, D.E.; Gaw, J.S. J. Med. Chem, 1993, 36, 101.
16. Marshall, W.S.; Goodson, T.; Gullinan, G.J.; Swanson, D.; Haisch, K.D.; Rinkema, L.E.; Leisch, J.H. J. Med. Chem. 1997, 30, 682.
17. Ashton, W.T.; Cantone, C.L.; Chang, L.L.; Hutchils, S.M.; Strelitz, R.A.; Malcolm, M.; Chang, S.L.; Lotti, V.J.; Farus,.K.D.; Chen, T.B.; Patiricia, B.; Terry, W.S.; Kivlighn, S.D.; Siegl, P.S. J. Med. Chem. 1993, 36, 591.
18. Philips, M.A. J. Chem. Soc. 1928, 2393.
19. nd edn, Kolkatta, 2005, 212-215.
20. th edn, New York, 1193, 504-508.
21. th edn,. New Delhi, 1995, 82-87.