Novel minimal invasive technique for measuring hepatic metabolism quantitatively in dairy cows exemplified by studying hepatic glucose-net production after dexamethasone treatment

Ruminant Physiology: Digestion, Metabolism, and Effects of Nutrition on Reproduction and Welfare

Volumn , Issue , 2023, Pages 664-667

  Starke, A ^a   Wussow, K ^a   Matthies, L ^a   Kusenda, M ^a   Busche, R ^a   Haudum, A ^a   Beineke, A ^a   Rehage, J ^a  

^a UNIVERSITY OF VETERINARY MEDICINE HANNOVER   (Germany)

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[No Author keywords available]

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EID: 79952014937     PISSN: None     EISSN: None     Source Type: Book    
DOI: None     Document Type: Chapter

References (10)

1. Baird, G.D. and R.J. Heitzman, 1971. Mode of action of a glucocorticoid on bovine intermediary metabolism. Possible role in controlling hepatic ketogenesis. Biochim. Biophys. Acta 252: 184-198.
2. Benson, J.A. and C.K. Reynolds, 2001. Effects of abomasal infusion of long-chain fatty acids on splanchnic metabolism of pancreatic and gut hormones in lactating dairy cows. J. Dairy Sci. 84: 1488-500.
3. Dake, Q., T. Pulinikunnil, A. Ding, G. Sanjoy, A. Ashraf, J.A. Pospisilik, R. Brownsey, R. Wambolt, M. Allard and B. Rodrigues, 2004. Single-dose dexamethasone induces whole-body insulin resistance and alters both cardiac fatty acid and carbohydrate metabolism. Diabetes 53: 1790-1797.
4. Hammon, H.M., S.N. Sauter, M. Reist, Y. Zbinden, C. Philipona, C. Morel and J.W. Blum, 2003. Dexamethasone and colostrum feeding affect hepatic gluconeogenic enzymes differently in neonatal calves. J. Anim. Sci. 81: 3095-3106.
5. Hammon, H.M., C. Philipona, Y. Zbinden, J.W. Blum and S. Donkin, 2005. Effects of dexamethasone and growth hormone treatment on hepatic gluconeogenic enzymes in calves. J. Dairy Sci. 88: 2107-2116.
6. Katz, M.L. and E.N. Bergman, 1969a. Simultaneous measurements of hepatic and portal venous blood flow in the sheep and dog. Am. J. Physiol. 216: 946-952.
7. Katz, M.L. and E.N. Bergman, 1969b. Hepatic and portal metabolism of glucose, free fatty acids, and ketone bodies in the sheep. Am. J. Physiol. 216: 953-960.
8. Kusenda, M., A. Starke, M. Kaske, M. Piechota, M. Hoeltershinken and J. Rehage 2009. Insulin resistance after single dose dexamethasone treatment in dairy cows. In: Chilliard, Y., F. Glasser, Y. Faulconnier, F. Bocquier, I. Veissier and M. Doreau (Eds.), Ruminant Physiology. Digestion, metabolism and effects of nutrition on reproduction and welfare. Wageningen Academic Publishers, Wageningen, the Netherlands. p. 562-563.
9. Nicod, N., V. Giusti, C. Besse and L. Tappy, 2003. Metabolic adaptations to dexamethasone-induced insulin resistance in healthy volunteers. Obesity Res. 11: 625-631.
10. Reynolds, C.K., H. Lapierre, H.F. Tyrrell, T.H. Elsasser, R.C. Staples, P. Gaudreau and P. Brazeau, 1992. Effects of growth hormone-releasing factor and feed intake on energy metabolism in growing beef steers: net nutrient metabolism by portal-drained viscera and liver. J. Anim. Sci. 70: 752-763.