Menopausal hormone therapy and risk of colorectal cancer in the European Prospective Investigation into Cancer and Nutrition

International Journal of Cancer

Volumn 128, Issue 8, 2011, Pages 1881-1889

  Tsilidis, Konstantinos K ^a,ab   Allen, Naomi E ^a   Key, Timothy J ^a   Sanjoaquin, Miguel A ^b   Bakken, Kjersti ^c   Berrino, Franco ^d   Fournier, Agnès ^e,f,g   Lund, Eiliv ^c   Overvad, Kim ^h   Olsen, Anja ⁱ   Tjønneland, Anne ⁱ   Byrnes, Graham ^j   Chajes, Veronique ^j   Rinaldi, Sabina ^j   Boutron Ruault, Marie Christine ^e,f,g   Clavel Chapelon, Francoise ^e,f,g   Chang Claude, Jenny ^k   Kaaks, Rudolf ^k   Bergmann, Manuela ^l   Boeing, Heiner ^l   Koumantaki, Yvoni ^m   Palli, Domenico ⁿ   Pala, Valeria ^d   Panico, Salvatore ^o   Tumino, Rosario ^p   Vineis, Paolo ^q   Bas Bueno De Mesquita, H ^s   Van Gils, Carla H ^t   Peeters, Petra H M ^t   Rodríguez, Laudina ^u   González, Carlos A ^v   Sánchez, María José ^w   Chirlaque, Maria Dolores ^x   Barricarte, Aurelio ^y   Dorronsoro, Miren ^x   Khaw, Kay Tee ^z   Rodwell, Sheila A ^aa   Norat, Teresa ^r   Romaguera, Dora ^r   Riboli, Elio ^r   more..

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b MALAWI LIVERPOOL WELLCOME TRUST CLINICAL RESEARCH PROGRAMME   (Malawi)

^c UNIVERSITY OF TROMSØ   (Norway)

^d NATIONAL CANCER INSTITUTE   (Italy)

^e INSERM   (France)

^f UNIVERSITÉ PARIS SACLAY   (France)

^g INSTITUT GUSTAVE ROUSSY   (France)

^h AARHUS UNIVERSITY   (Denmark)

ⁱ INSTITUTE OF CANCER EPIDEMIOLOGY   (Denmark)

^j INTERNATIONAL AGENCY FOR RESEARCH ON CANCER   (France)

^k GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^l GERMAN INSTITUTE OF HUMAN NUTRITION   (Germany)

^m UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

ⁿ CANCER RESEARCH AND PREVENTION INSTITUTE ISPO   (Italy)

^o UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^p CIVILE M P AREZZO HOSPITAL   (Italy)

^q ISI FOUNDATION   (Italy)

^r IMPERIAL COLLEGE LONDON   (United Kingdom)

^s NATIONAL INSTITUTE FOR PUBLIC HEALTH AND THE ENVIRONMENT   (Netherlands)

^t UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^u Health and Health Care Services Council   (Spain)

^v CATALAN INSTITUTE OF ONCOLOGY   (Spain)

^w ANDALUSIAN SCHOOL OF PUBLIC HEALTH   (Spain)

^x CIBER EPIDEMIOLOGÍA Y SALUD PÚBLICA CIBERESP   (Spain)

^y INSTITUTO DE SALUD PÚBLICA DE NAVARRA   (Spain)

^z UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^aa UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^ab UNIVERSITY OF OXFORD   (United Kingdom)

more..

Author keywords

cohort study; colorectal cancer; hormone replacement therapy

Indexed keywords

ANDROGEN; CONJUGATED ESTROGEN; ESTRADIOL; ESTROGEN; GESTAGEN; HORMONE; TIBOLONE;

ADULT; ALCOHOL CONSUMPTION; ARTICLE; BODY MASS; CANCER RISK; COLORECTAL CANCER; CONTROLLED STUDY; DENMARK; DIABETES MELLITUS; FEMALE; FOLLOW UP; FRANCE; GERMANY; HORMONAL THERAPY; HUMAN; ITALY; MAJOR CLINICAL STUDY; MENOPAUSAL SYNDROME; NETHERLANDS; NORWAY; PHYSICAL ACTIVITY; POSTMENOPAUSE; PRIORITY JOURNAL; SMOKING; SPAIN; TREATMENT DURATION; UNITED KINGDOM;

COHORT STUDIES; COLORECTAL NEOPLASMS; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; HORMONE REPLACEMENT THERAPY; HUMANS; MIDDLE AGED; NUTRITIONAL SCIENCES; POSTMENOPAUSE; PROGNOSIS; PROPORTIONAL HAZARDS MODELS; PROSPECTIVE STUDIES; QUESTIONNAIRES; RISK FACTORS;

EID: 79951994752     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.25504     Document Type: Article

References (36)

1. Grodstein F, Newcomb PA, Stampfer MJ,. Postmenopausal hormone therapy and the risk of colorectal cancer: a review and meta-analysis. Am J Med 1999; 106: 574-82. (Pubitemid 29231110)
2. Hebert-Croteau N,. A meta-analysis of hormone replacement therapy and colon cancer in women. Cancer Epidemiol Biomarkers Prev 1998; 7: 653-9. (Pubitemid 28374594)
3. Nanda K, Bastian LA, Hasselblad V, Simel DL,. Hormone replacement therapy and the risk of colorectal cancer: a meta-analysis. Obstet Gynecol 1999; 93: 880-8. (Pubitemid 29197937)
4. Chlebowski RT, Wactawski-Wende J, Ritenbaugh C, Hubbell FA, Ascensao J, Rodabough RJ, Rosenberg CA, Taylor VM, Harris R, Chen C, Adams-Campbell LL, White E,. Estrogen plus progestin and colorectal cancer in postmenopausal women. N Engl J Med 2004; 350: 991-1004. (Pubitemid 38269276)
5. Ritenbaugh C, Stanford JL, Wu L, Shikany JM, Schoen RE, Stefanick ML, Taylor V, Garland C, Frank G, Lane D, Mason E, McNeeley SG, et al. Conjugated equine estrogens and colorectal cancer incidence and survival: the Women's Health Initiative Randomized Clinical Trial. Cancer Epidemiol Biomarkers Prev 2008; 17: 2609-18.
6. Campbell PT, Newcomb P, Gallinger S, Cotterchio M, McLaughlin JR,. Exogenous hormones and colorectal cancer risk in Canada: associations stratified by clinically defined familial risk of cancer. Cancer Causes Control 2007; 18: 723-33. (Pubitemid 46988240)
7. Csizmadi I, Collet JP, Benedetti A, Boivin JF, Hanley JA,. Defining hormone replacement therapy in longitudinal studies: impact on measures of effect. Pharmacoepidemiol Drug Saf 2004; 13: 215-25. (Pubitemid 38514835)
8. Delellis Henderson K, Duan L, Sullivan-Halley J, Ma H, Clarke CA, Neuhausen SL, Templeman C, Bernstein L,. Menopausal hormone therapy use and risk of invasive colon cancer: the California Teachers Study. Am J Epidemiol 171: 415-25.
9. Dinger JC, Heinemann LA, Mohner S, Thai do M, Assmann A,. Colon cancer risk and different HRT formulations: a case-control study. BMC Cancer 2007; 7: 76.
10. Hildebrand JS, Jacobs EJ, Campbell PT, McCullough ML, Teras LR, Thun MJ, Gapstur SM,. Colorectal cancer incidence and postmenopausal hormone use by type, recency, and duration in cancer prevention study II. Cancer Epidemiol Biomarkers Prev 2009; 18: 2835-41.
11. Hoffmeister M, Raum E, Krtschil A, Chang-Claude J, Brenner H,. No evidence for variation in colorectal cancer risk associated with different types of postmenopausal hormone therapy. Clin Pharmacol Ther 2009; 86: 416-24.
12. Johnson JR, Lacey JV, Jr, Lazovich D, Geller MA, Schairer C, Schatzkin A, Flood A,. Menopausal hormone therapy and risk of colorectal cancer. Cancer Epidemiol Biomarkers Prev 2009; 18: 196-203.
13. Newcomb PA, Storer BE,. Postmenopausal hormone use and risk of large-bowel cancer. J Natl Cancer Inst 1995; 87: 1067-71.
14. Newcomb PA, Zheng Y, Chia VM, Morimoto LM, Doria-Rose VP, Templeton A, Thibodeau SN, Potter JD,. Estrogen plus progestin use, microsatellite instability, and the risk of colorectal cancer in women. Cancer Res 2007; 67: 7534-9. (Pubitemid 47206584)
15. Prentice RL, Pettinger M, Beresford SA, Wactawski-Wende J, Hubbell FA, Stefanick ML, Chlebowski RT,. Colorectal cancer in relation to postmenopausal estrogen and estrogen plus progestin in the Women's Health Initiative Clinical Trial and Observational Study. Cancer Epidemiol Biomarkers Prev 2009; 18: 1531-7.
16. Prihartono N, Palmer JR, Louik C, Shapiro S, Rosenberg L,. A case-control study of use of postmenopausal female hormone supplements in relation to the risk of large bowel cancer. Cancer Epidemiol Biomarkers Prev 2000; 9: 443-7. (Pubitemid 30265790)
17. Rennert G, Rennert HS, Pinchev M, Lavie O, Gruber SB,. Use of hormone replacement therapy and the risk of colorectal cancer. J Clin Oncol 2009; 27: 4542-7.
18. Tannen RL, Weiner MG, Xie D, Barnhart K,. Estrogen affects post-menopausal women differently than estrogen plus progestin replacement therapy. Hum Reprod 2007; 22: 1769-77. (Pubitemid 47055170)
19. Tannen RL, Weiner MG, Xie D, Barnhart K,. A simulation using data from a primary care practice database closely replicated the women's health initiative trial. J Clin Epidemiol 2007; 60: 686-95. (Pubitemid 46901002)
20. Wu AH, Siegmund KD, Long TI, Cozen W, Wan P, Tseng CC, Shibata D, Laird PW,. Hormone therapy, DNA methlyation and colon cancer. Carcinogenesis 2010; 31: 1060-7.
21. Riboli E, Hunt KJ, Slimani N, Ferrari P, Norat T, Fahey M, Charrondiere UR, Hemon B, Casagrande C, Vignat J, Overvad K, Tjonneland A, et al. European prospective investigation into cancer and nutrition (EPIC): study populations and data collection. Public Health Nutr 2002; 5: 1113-24. (Pubitemid 36313608)
22. Dossus L, Allen N, Kaaks R, Bakken K, Lund E, Tjonneland A, Olsen A, Overvad K, Clavel-Chapelon F, Fournier A, Chabbert-Buffet N, Boeing H, et al. Reproductive risk factors and endometrial cancer: the european prospective investigation into cancer and nutrition. Int J Cancer 2010; 127: 442-51.
23. World Health Organization Collaborating Centre for Drug Statistics Methodology NIoPH. The Anatomical Therapeutic Chemical Classification System. Available at:, 2010.
24. Stanczyk FZ,. All progestins are not created equal. Steroids 2003; 68: 879-90. (Pubitemid 37532412)
25. Ferrari P, Jenab M, Norat T, Moskal A, Slimani N, Olsen A, Tjonneland A, Overvad K, Jensen MK, Boutron-Ruault MC, Clavel-Chapelon F, Morois S, et al. Lifetime and baseline alcohol intake and risk of colon and rectal cancers in the European prospective investigation into cancer and nutrition (EPIC). Int J Cancer 2007; 121: 2065-72. (Pubitemid 47463172)
26. Friedenreich C, Norat T, Steindorf K, Boutron-Ruault MC, Pischon T, Mazuir M, Clavel-Chapelon F, Linseisen J, Boeing H, Bergman M, Johnsen NF, Tjonneland A, et al. Physical activity and risk of colon and rectal cancers: the European prospective investigation into cancer and nutrition. Cancer Epidemiol Biomarkers Prev 2006; 15: 2398-407. (Pubitemid 46048296)
27. Pischon T, Boeing H, Hoffmann K, Bergmann M, Schulze MB, Overvad K, van der Schouw YT, Spencer E, Moons KG, Tjonneland A, Halkjaer J, Jensen MK, et al. General and abdominal adiposity and risk of death in Europe. N Engl J Med 2008; 359: 2105-20.
28. Schoenfeld D,. Partial residuals for the proportional hazards regression model. Biometrika 1982; 69: 239-41.
29. Cochran WG,. The combination of estimates from different experiments. Biometrics 1954; 10: 101-29.
30. Hulley S, Furberg C, Barrett-Connor E, Cauley J, Grady D, Haskell W, Knopp R, Lowery M, Satterfield S, Schrott H, Vittinghoff E, Hunninghake D,. Noncardiovascular disease outcomes during 6.8 years of hormone therapy: heart and estrogen/progestin replacement study follow-up (HERS II). JAMA 2002; 288: 58-66. (Pubitemid 34705519)
31. McMichael AJ, Potter JD,. Reproduction, endogenous and exogenous sex hormones, and colon cancer: a review and hypothesis. J Natl Cancer Inst 1980; 65: 1201-7. (Pubitemid 11196006)
32. Campagnoli C, Biglia N, Altare F, Lanza MG, Lesca L, Cantamessa C, Peris C, Fiorucci GC, Sismondi P,. Differential effects of oral conjugated estrogens and transdermal estradiol on insulin-like growth factor 1, growth hormone and sex hormone binding globulin serum levels. Gynecol Endocrinol 1993; 7: 251-8. (Pubitemid 24042454)
33. Issa JP, Ottaviano YL, Celano P, Hamilton SR, Davidson NE, Baylin SB,. Methylation of the oestrogen receptor CpG island links ageing and neoplasia in human colon. Nat Genet 1994; 7: 536-40. (Pubitemid 24308343)
34. Schindler AE, Campagnoli C, Druckmann R, Huber J, Pasqualini JR, Schweppe KW, Thijssen JH,. Classification and pharmacology of progestins. Maturitas 2003; 46 (Suppl 1): S7-S16. (Pubitemid 37506058)
35. Chan AT, Giovannucci EL, Meyerhardt JA, Schernhammer ES, Curhan GC, Fuchs CS,. Long-term use of aspirin and nonsteroidal anti-inflammatory drugs and risk of colorectal cancer. JAMA 2005; 294: 914-23. (Pubitemid 41215460)
36. Rossouw JE, Anderson GL, Prentice RL, LaCroix AZ, Kooperberg C, Stefanick ML, Jackson RD, Beresford SA, Howard BV, Johnson KC, Kotchen JM, Ockene J,. Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results From the Women's Health Initiative randomized controlled trial. JAMA 2002; 288: 321-33. (Pubitemid 34761611)