Carnitine and coenzyme Q10 levels in individuals with Prader-Willi syndrome

American Journal of Medical Genetics, Part A

Volumn 155, Issue 3, 2011, Pages 569-573

  Miller, Jennifer L ^a   Lynn, Christy H ^a   Shuster, Jonathan ^b   Driscoll, Daniel J ^a  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF FLORIDA   (United States)

Author keywords

Carnitine; Coenzyme Q10; Prader Willi syndrome

Indexed keywords

CARNITINE; UBIDECARENONE;

ADOLESCENT; ADULT; ARTICLE; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; ENERGY METABOLISM; ENZYME METABOLISM; FEMALE; HUMAN; LEUKOCYTE; MALE; MOLECULAR DIAGNOSIS; OBESITY; PRADER WILLI SYNDROME; PRESCHOOL CHILD; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; SCHOOL CHILD;

CARNITINE; CASE-CONTROL STUDIES; CHILD; FEMALE; HUMANS; MALE; PRADER-WILLI SYNDROME; SIBLINGS; UBIQUINONE;

ANIMALIA;

EID: 79951962830     PISSN: 15524825     EISSN: 15524833     Source Type: Journal    
DOI: 10.1002/ajmg.a.33887     Document Type: Article

References (13)

1. 10): Biochemical, Functional, Medical and Therapeutic Aspects in Human Health and Disease. Scottsdale, AZ: Prominent Press. p. 151.
2. Bittel DC, Butler MG. 2005. Prader-Willi syndrome: Clinical genetics, cytogenetics and molecular biology. Expert Rev Mol Med 7: 1-20.
3. Butler MG, Dasouki M, Bittel D, Hunter S, Naini A, DiMauro S. 2003. Coenzyme Q10 levels in Prader-Willi syndrome: Comparison with obese and non-obese subjects. Am J Med Genet Part A 119A: 168-171.
4. Calvani M, Reda E, Arrigoni-Martelli E. 2000. Regulation by carnitine of myocardial fatty acid and carbohydrate metabolism under normal and pathological conditions. Basic Res Cardiol 95: 75-83.
5. Cassidy SB, Driscoll DJ. 2009. Prader-Willi syndrome. Eur J Hum Genet 17: 3-13.
6. Duncan AJ, Heales SJ, Mills K, Eaton S, Land JM, Hargreaves IP. 2005. Determination of coenzyme Q10 status in blood mononuclear cells, skeletal muscle, and plasma by HPLC with di-propoxy-coenzyme Q10 as an internal standard. Clin Chem 51: 2380-2382.
7. Eiholzer U, Meinhardt U, Rousson V, Petrovic N, Schlumpf M, l'Allemand D. 2008. Developmental profiles in young children with Prader-Labhart-Willi syndrome: Effects of weight and therapy with growth hormone or coenzyme Q10. Am J Med Genet Part A 146A: 873-880.
8. Goldstone AP. 2004. Prader-Willi syndrome: Advances in genetics, pathophysiology and treatment. Trends Endocrinol Metab 15: 12-20.
9. Kohlstadt I. 2009. Food and Nutrients in Disease Management. CRC Press. p. 114.
10. Littarru GP, Tiano L. 2005. Clinical aspects of coenzyme Q10: An update. Curr Opin Clin Nutr Metab Care 8: 641-646.
11. Noland RC, Koves TR, Seiler SE, Lum H, Lust RM, Ilkayeva O, Stevens RD, Hegardt FG, Muoio DM. 2009. Carnitine insufficiency caused by aging and overnutrition compromises mitochondrial performance and metabolic control. J Biol Chem 284: 22840-22852.
12. Seven M, Cengiz M, Tüzgen S, Iscan MY. 2001. Plasma carnitine levels in children with Down syndrome. Am J Hum Biol 13: 721-725.
13. Stephens FB, Constantin-Teodosiu D, Greenhaff PL. 2007. New insights concerning the role of carnitine in the regulation of fuel metabolism in skeletal muscle. J Physiol 581: 431-444.