Acotiamide hydrochloride (Z-338), a new selective acetylcholinesterase inhibitor, enhances gastric motility without prolonging QT interval in dogs: Comparison with cisapride, itopride, and mosapride

Journal of Pharmacology and Experimental Therapeutics

Volumn 336, Issue 3, 2011, Pages 791-800

  Matsunaga, Yugo ^a   Tanaka, Takao ^a   Yoshinaga, Koji ^a   Ueki, Shigeru ^a   Hori, Yuko ^a   Eta, Runa ^a   Kawabata, Yoshihiro ^a   Yoshii, Kazuyoshi ^a   Yoshida, Kenji ^a   Matsumura, Toshihiro ^a   Furuta, Shigeru ^a   Takei, Mineo ^a   Tack, Jan ^b   Itoh, Zen ^c  

^a ZERIA PHARMACEUTICAL CO LTD   (Japan)

^b UNIVERSITY HOSPITALS LEUVEN   (Belgium)

^c GUNMA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINESTERASE; ACOTIAMIDE; ATROPINE; CISAPRIDE; DOPAMINE 2 RECEPTOR; ITOPRIDE; MOSAPRIDE CITRATE; SEROTONIN RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; COMPARATIVE STUDY; CONTROLLED STUDY; DELAYED GASTRIC EMPTYING; DYSPEPSIA; ENZYME INHIBITION; GASTRIC DYSMOTILITY; HEART MUSCLE POTENTIAL; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL; QT INTERVAL; STOMACH EMPTYING; STOMACH MOTILITY;

ANIMALS; BENZAMIDES; BENZYL COMPOUNDS; CHO CELLS; CHOLINESTERASE INHIBITORS; CISAPRIDE; CRICETINAE; CRICETULUS; DOGS; GASTROINTESTINAL MOTILITY; GUINEA PIGS; HEART CONDUCTION SYSTEM; HUMANS; MALE; MORPHOLINES; THIAZOLES;

EID: 79951961277     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.110.174847     Document Type: Article

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