The use of benzodiazepine monotherapy for major depression before and after implementation of guidelines for benzodiazepine use

Journal of Clinical Pharmacy and Therapeutics

Volumn 36, Issue 5, 2011, Pages 577-584

  Lai, I C ^a   Wang, M T ^b   Wu, B J ^c   Wu, H H ^c   Lian, P W ^b  

^a BUDDHIST TZU CHI GENERAL HOSPITAL   (Taiwan)

^b NATIONAL DEFENSE MEDICAL CENTER   (Taiwan)

^c TRI SERVICE GENERAL HOSPITAL   (Taiwan)

Author keywords

antidepressant; benzodiazepines; claims data; guidelines; major depression

Indexed keywords

BENZODIAZEPINE DERIVATIVE; BROMAZEPAM; CLONAZEPAM; ESTAZOLAM; FLUDIAZEPAM; FLUNITRAZEPAM; FLURAZEPAM; LORAZEPAM;

ADULT; ARTICLE; FEMALE; HOSPITAL PATIENT; HUMAN; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; MAJOR DEPRESSION; MALE; MONOTHERAPY; OUTPATIENT; PATIENT COMPLIANCE; PRACTICE GUIDELINE; PRESCRIPTION; RETROSPECTIVE STUDY; TAIWAN; TREATMENT REFUSAL;

ADULT; AGED; BENZODIAZEPINES; DATABASES, FACTUAL; DEPRESSIVE DISORDER, MAJOR; DRUG PRESCRIPTIONS; DRUG THERAPY, COMBINATION; FEMALE; GUIDELINE ADHERENCE; HUMANS; INPATIENTS; LONGITUDINAL STUDIES; MALE; MIDDLE AGED; OUTPATIENTS; PHYSICIAN'S PRACTICE PATTERNS; PRACTICE GUIDELINES AS TOPIC; RETROSPECTIVE STUDIES; TIME FACTORS;

EID: 79951961123     PISSN: 02694727     EISSN: 13652710     Source Type: Journal    
DOI: 10.1111/j.1365-2710.2010.01213.x     Document Type: Article

References (13)

1. Lesser IM, Rubin RT, Pecknold JC, et al. (1988) Secondary depression in panic disorder and agoraphobia I. Frequency, severity, and response to treatment. Archives of General Psychiatry, 45, 437-443.
2. Warner MD, Peabody CA, Whiteford HA, Hollister LE, (1988) Alprazolam as an antidepressant. Journal of Clinical Psychiatry, 49, 148-150.
3. Lader MH, Petursson H, (1981) Benzodiazepine derivatives-side effects and dangers. Biological Psychiatry, 16, 1195-1201. (Pubitemid 12197055)
4. Ryan HF, Merrill FB, Scott GE, Krebs R, Thompson BL, (1968) Increase in suicidal thoughts and tendencies. Association with diazepam therapy. The Journal of the American Medical Association, 203, 1137-1139.
5. Assem-Hilger E, Jungwirth S, Weissgram S, Kirchmeyr W, Fischer P, Barnas C, (2009) Benzodiazepine use in the elderly: an indicator for inappropriately treated geriatric depression? International Journal of Geriatric Psychiatry, 24, 563-569.
6. Department of Health, Taiwan (2004) Guidelines for benzodiazepine using in sedation and hypnosis. Available at: (accessed 25 June 2010).
7. Huang WF, Lai IC, (2006) Potentially inappropriate prescribing for insomnia in elderly outpatients in Taiwan. International Journal of Clinical Pharmacology and Therapeutics, 44, 335-342.
8. Olfson M, Marcus SC, Druss B, Elinson L, Tanielian T, Pincus HA, (2002) National trends in the outpatient treatment of depression. The Journal of the American Medical Association, 287, 203-209. (Pubitemid 34251945)
9. Valenstein M, Taylor KK, Austin K, Kales HC, McCarthy JF, Blow FC, (2004) Benzodiazepine use among depressed patients treated in mental health settings. The American Journal of Psychiatry, 161, 654-661. (Pubitemid 38445509)
10. Leclerc-Foucras S, Bagheri H, Samii K, Montastruc JL, Lapeyre-Mestre M, (2007) Modifications of low-molecular weight heparin use in a French university hospital after implementation of new guidelines. Drug Safety, 30, 409-417. (Pubitemid 46740337)
11. Schumock GT, Blackburn JC, Nutescu EA, Walton SM, Finley JM, Lewis RK, (2004) Impact of prescribing guidelines for inpatient anticoagulation. The Annals of Pharmacotherapy, 38, 1570-1575. (Pubitemid 39302596)
12. Steinbrook R, (2007) Guidance for guidelines. New England Journal of Medicine, 356, 331-333. (Pubitemid 46148775)
13. Feder G, Eccles M, Grol R, Griffiths C, Grimshaw J, (1999) Clinical guidelines: using clinical guidelines. British Medical Journal, 318, 728-730. (Pubitemid 29192002)