Randomized phase III study comparing the efficacy and safety of irinotecan plus S-1 with S-1 alone as first-line treatment for advanced gastric cancer (study GC0301/TOP-002)
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Randomized phase III study comparing irinotecan combined with 5-fluorouracil and folinic acid to cisplatin combined with 5-fluorouracil in chemotherapy naive patients with advanced adenocarcinoma of the stomach or esophagogastric junction
M Dank J Zaluski C Barone V Valvere S Yalcin C Peschel, et al. 2008 Randomized phase III study comparing irinotecan combined with 5-fluorouracil and folinic acid to cisplatin combined with 5-fluorouracil in chemotherapy naive patients with advanced adenocarcinoma of the stomach or esophagogastric junction Ann Oncol 19 1450 1457 18558665 10.1093/annonc/mdn166 1:STN:280: DC%2BD1cvotFCmtA%3D%3D
N Boku S Yamamoto H Fukuda K Shirao T Doi A Sawaki, et al. 2009 Fluorouracil versus combination of irinotecan plus cisplatin versus S-1 in metastatic gastric cancer: a randomized phase 3 study Lancet Oncol 10 1063 1069 19818685 10.1016/S1470-2045(09)70259-1 1:CAS:528:DC%2BD1MXhtlGit7bI
Randomized phase III study of S-1 alone versus S-1 + cisplatin in the treatment for advanced gastric cancer (The SPIRITS trial) SPIRITS: S-1 plus cisplatin vs S-1 in RCT in the treatment for stomach cancer
W Koizumi H Narahara T Hara A Takagane T Akiya M Takagi, et al. 2008 Randomized phase III study of S-1 alone versus S-1 + cisplatin in the treatment for advanced gastric cancer (The SPIRITS trial) SPIRITS: S-1 plus cisplatin vs S-1 in RCT in the treatment for stomach cancer Lancet Oncol 9 215 221 18282805 10.1016/S1470-2045(08)70035-4 1:CAS:528:DC%2BD1cXivVaqtb4%3D
Randomized phase III trial of fluorouracil alone versus fluorouracil plus cisplatin versus uracil and tegafur plus mitomycin in patients with advanced gastric cancer: JCOG study 9205
A Ohtsu Y Shimada K Shirao N Boku I Hyodo H Saito, et al. 2003 Randomized phase III trial of fluorouracil alone versus fluorouracil plus cisplatin versus uracil and tegafur plus mitomycin in patients with advanced gastric cancer: JCOG study 9205 J Clin Oncol 21 54 59 12506170 10.1200/JCO.2003.04.130 1:CAS:528:DC%2BD2cXpsVWru7k%3D
Survival prolongation after treatment failure in patients with advanced gastric cancer (AGC): Results from combined analysis of JCOG9205 and JCOG9912 [abstract no.4061]
A Takashima N Boku K Kato J Mizusawa K Nakamura H Fukuda, et al. 2010 Survival prolongation after treatment failure in patients with advanced gastric cancer (AGC): results from combined analysis of JCOG9205 and JCOG9912 [abstract no.4061] J Clin Oncol 28 Suppl 15S 4061
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Irinotecan versus best supportive care (BSC) as second-line therapy in gastric cancer: A randomized phase III study of the Arbeitsgemeinschaft Internistische Onkologie (AIO) [abstract no. 4540]
PC Thuss-Patience A Kretzschmar T Deist A Hinke D Bichev B Lebedinzew, et al. 2009 Irinotecan versus best supportive care (BSC) as second-line therapy in gastric cancer: a randomized phase III study of the Arbeitsgemeinschaft Internistische Onkologie (AIO) [abstract no. 4540] J Clin Oncol 27 Suppl 15S 4540
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