-
1
-
-
84855637937
-
-
Aicuris 09November2009
-
Aicuris. www.aicuris.com, 09 November 2009.
-
-
-
-
2
-
-
0034933726
-
Evaluating phenotype and genotype of drug-resistant strains in herpesviruses
-
DOI 10.1385/MB:18:2:155
-
G. Andrei, P. Fiten, E. De Clercq, R. Snoeck, and G. Opdenakker Evaluating phenotype and genotype of drug-resistant strains in herpesvirus Mol. Biotechnol. 18 2001 155 167 (Pubitemid 32646246)
-
(2001)
Applied Biochemistry and Biotechnology - Part B Molecular Biotechnology
, vol.18
, Issue.2
, pp. 155-167
-
-
Andrei, G.1
Fiten, P.2
De Clercq, E.3
Snoeck, R.4
Opdenakker, G.5
-
3
-
-
33947286682
-
Superior efficacy of helicase-primase inhibitor BAY 57-1293 for herpes infection and latency in the guinea pig model of human genital herpes disease
-
J. Baumeister, R. Fischer, P. Eckenberg, K. Henninger, H. Ruebsamen-Waigmann, and G. Kleymann Superior efficacy of helicase-primase inhibitor BAY 57-1293 for herpes infection and latency in the guinea pig model of human genital herpes disease Antivir. Chem. Chemother. 18 2007 35 48 (Pubitemid 46426936)
-
(2007)
Antiviral Chemistry and Chemotherapy
, vol.18
, Issue.1
, pp. 35-48
-
-
Baumeister, J.1
Fischer, R.2
Eckenberg, P.3
Henninger, K.4
Ruebsamen-Waigmann, H.5
Kleymann, G.6
-
4
-
-
0036093580
-
Potent in vivo antiviral activity of the herpes simplex virus primase-helicase inhibitor BAY 57-1293
-
DOI 10.1128/AAC.46.6.1766-1772.2002
-
U.A.K. Betz, R. Fischer, G. Kleymann, M. Hendrix, and H. Rübsamen-Waigmann Potent in vivo antiviral activity of the herpes simplex virus primase-helicase inhibitor BAY57-1293 Antimicrob. Agents Chemother. 46 2002 1766 1772 (Pubitemid 34535195)
-
(2002)
Antimicrobial Agents and Chemotherapy
, vol.46
, Issue.6
, pp. 1766-1772
-
-
Betz, U.A.K.1
Fischer, R.2
Kleymann, G.3
Hendrix, M.4
Rubsamen-Waigmann, H.5
-
5
-
-
47049098403
-
Herpes simplex virus helicase-primase inhibitors: Recent findings from the study of drug resistance mutations
-
S. Biswas, and H.J. Field Herpes simplex virus helicase-primase inhibitors: recent findings from the study of drug resistance mutations Antivir. Chem. Chemother. 19 2008 1 6
-
(2008)
Antivir. Chem. Chemother.
, vol.19
, pp. 1-6
-
-
Biswas, S.1
Field, H.J.2
-
6
-
-
84878855948
-
Helicase-primase inhibitors - A new approach to combating herpes simplex and varicella-zoster viruses
-
In: E. De Clercq (Ed.) Whiley
-
Biswas, S., Field, H.J. (in press). Helicase-primase inhibitors - a new approach to combating herpes simplex and varicella-zoster viruses. In: E. De Clercq (Ed.), Antiviral Drug Strategies, Whiley.
-
Antiviral Drug Strategies
-
-
Biswas, S.1
Field, H.J.2
-
7
-
-
33947241644
-
The helicase primase inhibitor, BAY 57-1293 shows potent therapeutic antiviral activity superior to famciclovir in BALB/c mice infected with herpes simplex virus type 1
-
DOI 10.1016/j.antiviral.2006.11.006, PII S0166354206003482
-
S. Biswas, L. Jennens, and H.J. Field The helicase primase inhibitor, BAY 57-1293 shows potent therapeutic antiviral activity superior to famciclovir in BALB/c mice infected with herpes simplex virus type 1 Antivir. Res. 75 2007 30 35 (Pubitemid 46621066)
-
(2007)
Antiviral Research
, vol.75
, Issue.1
, pp. 30-35
-
-
Biswas, S.1
Jennens, L.2
Field, H.J.3
-
8
-
-
34547162397
-
Single amino acid substitutions in the HSV-1 helicase protein that confer resistance to the helicase-primase inhibitor BAY 57-1293 are associated with increased or decreased virus growth characteristics in tissue culture
-
DOI 10.1007/s00705-007-0964-7
-
S. Biswas, L. Jennens, and H.J. Field Single amino acid substitutions in the HSV-1 helicase protein that confer resistance to the helicase-primase inhibitor BAY 57-1293 are associated with increased or decreased virus growth characteristics in tissue culture Arch. Virol. 152 2007 1489 1500 (Pubitemid 47124949)
-
(2007)
Archives of Virology
, vol.152
, Issue.8
, pp. 1489-1500
-
-
Biswas, S.1
Jennens, L.2
Field, H.J.3
-
9
-
-
42149087645
-
A single drug-resistance mutation in HSV-1 UL52 primase points to a difference between two helicase-primase inhibitors in their mode of interaction with the antiviral target
-
DOI 10.1093/jac/dkn057
-
S. Biswas, G. Kleymann, M. Swift, L. Tiley, J. Lyall, J. Aguirre-Hernández, and H.J. Field A single drug-resistance mutation in HSV-1 UL52 primase points to a difference between two helicase-primase inhibitors in their mode of interaction with the antiviral target J. Antimicrob. Chemother. 61 2008 1044 1047 (Pubitemid 351524447)
-
(2008)
Journal of Antimicrobial Chemotherapy
, vol.61
, Issue.5
, pp. 1044-1047
-
-
Biswas, S.1
Kleymann, G.2
Swift, M.3
Tiley, L.S.4
Lyall, J.5
Aguirre-Hernendez, J.6
Field, H.J.7
-
10
-
-
69449084164
-
A mutation in helicase motif IV of herpes simplex virus type 1 UL5 that results in reduced growth in vitro and lower virulence in a murine infection model is related to the predicted helicase structure
-
S. Biswas, R.N. Muguel, S. Sukla, and H.J. Field A mutation in helicase motif IV of herpes simplex virus type 1 UL5 that results in reduced growth in vitro and lower virulence in a murine infection model is related to the predicted helicase structure J. Gen. Virol. 90 2009 1937 1942
-
(2009)
J. Gen. Virol.
, vol.90
, pp. 1937-1942
-
-
Biswas, S.1
Muguel, R.N.2
Sukla, S.3
Field, H.J.4
-
11
-
-
34547837615
-
Detection of HSV-1 variants highly resistant to the helicase-primase inhibitor BAY 57-1293 at high frequency in 2 of 10 recent clinical isolates of HSV-1
-
DOI 10.1093/jac/dkm182
-
S. Biswas, C. Smith, and H.J. Field Detection of HSV-1 variants highly resistant to the helicase-primase inhibitor BAY 57-1293 at high frequency in two of ten recent clinical isolates of HSV-1 J. Antimicrob. Chemother. 60 2007 274 279 (Pubitemid 47243874)
-
(2007)
Journal of Antimicrobial Chemotherapy
, vol.60
, Issue.2
, pp. 274-279
-
-
Biswas, S.1
Smith, C.2
Field, H.J.3
-
12
-
-
33947220269
-
High frequency of spontaneous helicase-primase inhibitor (BAY 57-1293) drug-resistant variants in certain laboratory isolates of HSV-1
-
S. Biswas, M. Swift, and H.J. Field High frequency of spontaneous helicase primase inhibitor (BAY 57-1293) drug-resistant variants in certain laboratory isolates of HSV-1 Antivir. Chem. Chemother. 18 2007 13 23 (Pubitemid 46426934)
-
(2007)
Antiviral Chemistry and Chemotherapy
, vol.18
, Issue.1
, pp. 13-23
-
-
Biswas, S.1
Swift, M.2
Field, H.J.3
-
13
-
-
50049091989
-
Mutations close to functional motif IV in HSV-1 UL5 helicase that confer resistance to HSV helicase-primase inhibitors, variously affect virus growth rate and pathogenicity
-
S. Biswas, L.S. Tiley, H. Zimmermann, A. Birkmann, and H.J. Field Mutations close to functional motif IV in HSV-1 UL5 helicase that confer resistance to HSV helicase-primase inhibitors, variously affect virus growth rate and pathogenicity Antivir. Res. 80 2008 81 85
-
(2008)
Antivir. Res.
, vol.80
, pp. 81-85
-
-
Biswas, S.1
Tiley, L.S.2
Zimmermann, H.3
Birkmann, A.4
Field, H.J.5
-
14
-
-
70350503284
-
Herpes simplex virus-1 helicase-primase: Roles of each subunit in DNA binding and phosphodiester bond formation
-
N.A. Cavanaugh, K.A. Ramirez-Aguilar, M. Urban, and R.D. Kuchta Herpes simplex virus-1 helicase-primase: roles of each subunit in DNA binding and phosphodiester bond formation Biochemistry 48 2009 10199 10207
-
(2009)
Biochemistry
, vol.48
, pp. 10199-10207
-
-
Cavanaugh, N.A.1
Ramirez-Aguilar, K.A.2
Urban, M.3
Kuchta, R.D.4
-
15
-
-
77954724450
-
ASP2151 a novel helicase-primase inhibitor, possesses antiviral 1 activity against varicella-zoster virus and herpes simplex virus types 1 and 2
-
K. Chono, K. Katsumata, T. Kontani, M. Kobayashi, K. Sudo, T. Yokota, K. Konno, Y. Shimizu, and H. Suzuki ASP2151 a novel helicase-primase inhibitor, possesses antiviral 1 activity against varicella-zoster virus and herpes simplex virus types 1 and 2 J. Antimicrob. Chemother. 65 2010 1733 1741
-
(2010)
J. Antimicrob. Chemother.
, vol.65
, pp. 1733-1741
-
-
Chono, K.1
Katsumata, K.2
Kontani, T.3
Kobayashi, M.4
Sudo, K.5
Yokota, T.6
Konno, K.7
Shimizu, Y.8
Suzuki, H.9
-
16
-
-
0031977160
-
Survey of resistance of herpes simplex virus to acyclovir in northwest England
-
J. Christophers, J. Clayton, J. Craske, R. Ward, P. Collins, M. Trowbridge, and G. Darby Survey of resistance of herpes simplex virus to acyclovir in northwest England Antimicrob. Agents Chemother. 42 1998 868 872 (Pubitemid 28216369)
-
(1998)
Antimicrobial Agents and Chemotherapy
, vol.42
, Issue.4
, pp. 868-872
-
-
Christophers, J.1
Clayton, J.2
Craske, J.3
Ward, R.4
Collins, P.5
Trowbridge, M.6
Darby, G.7
-
17
-
-
0023197385
-
Characterisation of acyclovir-resistant and -sensitive clinical herpes simplex virus isolates from an immunocompromised patient
-
J. Christophers, and R.N. Sutton Characterization of acyclovir-resistant and sensitive clinical isolates of herpes simplex virus isolates from an immunocompromised patient J. Antimicrob. Chemother. 20 1987 389 398 (Pubitemid 17140428)
-
(1987)
Journal of Antimicrobial Chemotherapy
, vol.20
, Issue.3
, pp. 389-398
-
-
Christophers, J.1
Sutton, R.N.P.2
-
19
-
-
0036107516
-
Herpes simplex virus helicase-primase inhibitors are active in animal models of human disease
-
DOI 10.1038/nm0402-386
-
J.J. Crute, C.A. Grygon, K.D. Hargrave, B. Simoneau, A-M. Faucher, G. Bolger, P. Kibler, M. Liuzzi, and M.G. Cordingley Herpes simplex virus helicase-primase inhibitors are active in animal models of human disease Nat. Med. 8 2002 386 391 (Pubitemid 34407034)
-
(2002)
Nature Medicine
, vol.8
, Issue.4
, pp. 386-391
-
-
Crute, J.J.1
Grygon, C.A.2
Hargrave, K.D.3
Simoneau, B.4
Faucher, A.-M.5
Bolger, G.6
Kibler, P.7
Liuzzi, M.8
Cordingley, M.G.9
-
20
-
-
0019350295
-
Altered substrate specificity of herpes simplex virus thymidine kinase confers acyclovir-resistance
-
DOI 10.1038/289081a0
-
G. Darby, H.J. Field, and S. Salisbury Altered substrate specificity of herpes simplex thymidine kinase confers acyclovir-resistance Nature 289 1981 81 83 (Pubitemid 11178460)
-
(1981)
Nature
, vol.289
, Issue.5793
, pp. 81-83
-
-
Darby, G.1
Field, H.J.2
Salisbury, S.A.3
-
21
-
-
0026073154
-
Association of DNA helicase and primase activities with a subassembly of the herpes simplex virus 1 helicase-primase composed of the UL5 and UL52 gene products
-
M.S. Dodson, and I.R. Lehman Association of DNA helicase and primase activities with a subassembly of the herpes simplex virus 1 helicase-primase composed of the UL5 and UL52 gene products Proc. Natl. Acad. Sci. U.S.A. 88 1991 1105 1109 (Pubitemid 21916173)
-
(1991)
Proceedings of the National Academy of Sciences of the United States of America
, vol.88
, Issue.4
, pp. 1105-1109
-
-
Dodson, M.S.1
Lehman, I.R.2
-
23
-
-
50949091696
-
Acyclovir-resistant corneal HSV-1 isolates from patients with herpetic keratitis
-
R. Duan, R.D. de Vries, A.D. Osterhaus, L. Remeijer, and G.M. Verjans Acyclovir-resistant corneal HSV-1 isolates from patients with herpetic keratitis J. Inf. Dis. 198 2008 659 663
-
(2008)
J. Inf. Dis.
, vol.198
, pp. 659-663
-
-
Duan, R.1
De Vries, R.D.2
Osterhaus, A.D.3
Remeijer, L.4
Verjans, G.M.5
-
24
-
-
0034980063
-
Herpes simplex virus antiviral drug resistance - Current trends and future prospects
-
DOI 10.1016/S1386-6532(00)00169-4, PII S1386653200001694
-
H.J. Field Herpes simplex virus antiviral drug resistance - current trends and future prospects J. Clin. Virol. 21 2001 261 269 (Pubitemid 32499236)
-
(2001)
Journal of Clinical Virology
, vol.21
, Issue.3
, pp. 261-269
-
-
Field, H.J.1
-
25
-
-
9144248691
-
Antiviral drugs: A short history of their discovery and development
-
H.J. Field, and E. De Clercq Antiviral drugs: a short history of their discovery and development Microbiol. Today 31 2004 58 61
-
(2004)
Microbiol. Today
, vol.31
, pp. 58-61
-
-
Field, H.J.1
De Clercq, E.2
-
26
-
-
0031468435
-
Can herpes simplex virus latency be prevented using conventional nucleoside analogue chemotherapy?
-
H.J. Field, and A.M. Thackray Can herpes simplex virus latency be prevented using conventional nucleoside analogue chemotherapy? Antivir. Chem. Chemother. 8 Suppl. 1 1997 59 66
-
(1997)
Antivir. Chem. Chemother.
, vol.8
, Issue.SUPPL. 1
, pp. 59-66
-
-
Field, H.J.1
Thackray, A.M.2
-
27
-
-
0034018135
-
Early therapy with valaciclovir or famciclovir reduces but does not abrogate herpes simplex virus neuronal latency
-
H.J. Field, and A.M. Thackray Early therapy with valaciclovir or famciclovir reduces but does not abrogate herpes simplex virus neuronal latency Nucleos. Nucleot. Nucl. Acids 19 2000 461 470 (Pubitemid 30230054)
-
(2000)
Nucleosides, Nucleotides and Nucleic Acids
, vol.19
, Issue.1-2
, pp. 461-470
-
-
Field, H.J.1
Thackray, A.M.2
-
28
-
-
0018141515
-
The pathogenicity of thymidine kinase-deficient mutants of herpes simplex virus in mice
-
H.J. Field, and P. Wildy The pathogenicity of thymidine kinase-deficient mutants of herpes simplex virus in mice Journal of Hygiene, Cambridge 81 1978 267 277 (Pubitemid 9021091)
-
(1978)
Journal of Hygiene
, vol.81
, Issue.2
, pp. 267-277
-
-
Field, H.J.1
Wildy, P.2
-
30
-
-
43049180320
-
Genotypic detection of acyclovir-resistant HSV-1: Characterization of 67 ACV-sensitive and 14 ACV-resistant viruses
-
E. Frobert, J.C. Cortay, T. Ooka, F. Najioullah, D. Thouvenot, B. Lina, and F. Morfin Genotypic detection of acyclovir-resistant HSV-1: characterization of 67 ACV-sensitive and 14 ACV-resistant viruses Antivir. Res. 79 2008 28 36
-
(2008)
Antivir. Res.
, vol.79
, pp. 28-36
-
-
Frobert, E.1
Cortay, J.C.2
Ooka, T.3
Najioullah, F.4
Thouvenot, D.5
Lina, B.6
Morfin, F.7
-
31
-
-
77958469210
-
Efficacy of acute oral treatment with ASP2151 or valacyclovir (VACV) against cutaneous infection with herpes simplex virus (HSV) type 1 in mice
-
September 12-15, San Francisco, USA
-
K. Katsumata, K. Chono, T. Kontani, K. Sudo, Y. Shimizu, and H. Suzuki Efficacy of acute oral treatment with ASP2151 or valacyclovir (VACV) against cutaneous infection with herpes simplex virus (HSV) type 1 in mice Poster V-1742, Interscience Conference on Antimicrobial Agents and Chemotherapy September 12-15, San Francisco, USA 2009
-
(2009)
Poster V-1742, Interscience Conference on Antimicrobial Agents and Chemotherapy
-
-
Katsumata, K.1
Chono, K.2
Kontani, T.3
Sudo, K.4
Shimizu, Y.5
Suzuki, H.6
-
32
-
-
38549166190
-
Efficacy of a helicase-primase inhibitor in animal models of ocular herpes simplex virus type 1 infection
-
DOI 10.1089/jop.2007.0084
-
H.E. Kaufman, E.D. Varnell, B.M. Gebhardt, H.W. Thompson, E. Atwal, H. Rübsamen-Waigmann, and G. Kleymann Efficacy of a helicase-primase inhibitor in animal models of ocular herpes simplex virus type 1 infection J. Ocul. Pharmacol. Ther. 24 2008 34 42 (Pubitemid 351156639)
-
(2008)
Journal of Ocular Pharmacology and Therapeutics
, vol.24
, Issue.1
, pp. 34-42
-
-
Kaufman, H.E.1
Varnell, E.D.2
Gebhardt, B.M.3
Thompson, H.W.4
Atwal, E.5
Rubsamen-Waigmann, H.6
Kleymann, G.7
-
33
-
-
0036111626
-
New helicase-primase inhibitors as drug candidates for the treatment of herpes simplex disease
-
DOI 10.1038/nm0402-392
-
G. Kleymann, R. Fischer, U.A. Betz, M. Hendrix, W. Bender, U. Schneider, G. Handke, P. Eckenberg, G. Hewlett, V. Pevzner, J. Baumeister, O. Weber, K. Henninger, J. Keldenich, A. Jensen, J. Kolb, U. Bach, A. Popp, J. Maben, I. Frappa, D. Haebich, O. Lockhoff, and H. Rubsamen-Waigmann New helicase-primase inhibitors as drug candidates for the treatment of herpes simplex disease Nat. Med. 8 2002 392 398 (Pubitemid 34407035)
-
(2002)
Nature Medicine
, vol.8
, Issue.4
, pp. 392-398
-
-
Kleymann, G.1
Fischer, R.2
Betz, U.A.K.3
Hendrix, M.4
Bender, W.5
Schneider, U.6
Handke, G.7
Eckenberg, P.8
Hewlett, G.9
Pevzner, V.10
Baumeister, J.11
Weber, O.12
Henninger, K.13
Keldenich, J.14
Jensen, A.15
Kolb, J.16
Bach, U.17
Popp, A.18
Maben, J.19
Frappa, I.20
Haebich, D.21
Lockhoff, O.22
Rubsamen-Waigmann, H.23
more..
-
34
-
-
0027362888
-
Brief report: Recurrent acyclovir-resistant genital herpes in an immunocompetent patient
-
DOI 10.1056/NEJM199312093292405
-
R.G. Kost, E.L. Hill, M. Tigges, and S. Straus Recurrent acyclovir-resistant genital herpes in an immunocompetent patient N. Engl. J. Med. 329 1993 1777 1782 (Pubitemid 23355551)
-
(1993)
New England Journal of Medicine
, vol.329
, Issue.24
, pp. 1777-1782
-
-
Kost, R.G.1
Hill, E.L.2
Tigges, M.3
Straus, S.E.4
-
35
-
-
0022271262
-
Selection and characterization of acyclovir-resistant herpes simplex virus type 1 mutants inducing altered DNA polymerase activities
-
DOI 10.1016/0042-6822(85)90009-1
-
B.A. Larder, and G. Darby Selection and characterization of acyclovir-resistant herpes simplex virus type 1 mutants inducing altered DNA polymerase activities Virology 146 1985 262 271 (Pubitemid 16240381)
-
(1985)
Virology
, vol.146
, Issue.2
, pp. 262-271
-
-
Larder, B.1
Darby, G.2
-
36
-
-
0020633163
-
Characterization of abnormal thymidine kinase induced by drug-resistant strains of herpes simplex virus type 1
-
B.A. Larder, Y.C. Cheng, and G. Darby Characterization of abnormal thymidine kinases induced by drug-resistant strains of herpes simplex virus type 1 J. Gen. Virol. 64 1983 523 532 (Pubitemid 13125611)
-
(1983)
Journal of General Virology
, vol.64
, Issue.3
, pp. 523-532
-
-
Larder, B.A.1
Cheng, Y.C.2
Darby, G.3
-
37
-
-
8644267364
-
Isolation and characterization of herpes simplex virus type 1 resistant to aminothiazolylphenyl-based inhibitors of the viral helicase-primase
-
DOI 10.1016/j.antiviral.2004.02.007, PII S0166354204000506
-
M. Liuzzi, P. Kibler, C. Bousquet, F. Harji, G. Bolger, M. Garneau, N. Lapeyre, R.S. McCollum, A.-M. Faucher, B. Simoneau, and M.G. Cordingley Isolation and characterization of herpes simplex virus type 1 resistant to aminothiazolylphenyl-based inhibitors of the viral helicase-primase Antivir. Res. 64 2004 161 170 (Pubitemid 39506836)
-
(2004)
Antiviral Research
, vol.64
, Issue.3
, pp. 161-170
-
-
Liuzzi, M.1
Kibler, P.2
Bousquet, C.3
Harji, F.4
Bolger, G.5
Garneau, M.6
Lapeyre, N.7
McCollum, R.S.8
Faucher, A.-M.9
Simoneau, B.10
Cordingley, M.G.11
-
38
-
-
0027492163
-
The structure and function of the HSV DNA replication proteins: Defining novel antiviral targets
-
DOI 10.1016/0166-3542(93)90001-Y
-
J.T. Matthews, B.J. Terry, and A.K. Field The structure and function of the HSV DNA replication proteins: defining novel antiviral targets Antivir. Res. 20 1993 89 114 (Pubitemid 23024877)
-
(1993)
Antiviral Research
, vol.20
, Issue.2
, pp. 89-114
-
-
Matthews, J.T.1
Terry, B.J.2
Field, A.K.3
-
39
-
-
0020315762
-
Herpes simplex virus variants resistant to high concentrations of acyclovir exist in clinical isolates
-
D.S. Parris, and J.E. Harrington Herpes simplex virus variants resistant to high concentrations of acyclovir exist in clinical isolates Antimicrob. Agents Chemother. 22 1982 71 77 (Pubitemid 12029996)
-
(1982)
Antimicrobial Agents and Chemotherapy
, vol.22
, Issue.1
, pp. 71-77
-
-
Parris, D.S.1
Harrington, J.E.2
-
40
-
-
0141786611
-
Profiling penciclovir susceptibility and prevalence of resistance of herpes simplex virus isolates across eleven clinical trials
-
DOI 10.1007/s00705-003-0124-7
-
R.T. Sarisky, T.H. Bacon, R.J. Boon, K.E. Duffy, K.M. Esser, J. Leary, L.A. Locke, T.T. Nguyen, M.R. Quail, and R. Saltzman Profiling penciclovir susceptibility and prevalence of resistance of herpes simplex virus isolates across eleven clinical trials Arch. Virol. 148 2003 1757 1769 (Pubitemid 37144179)
-
(2003)
Archives of Virology
, vol.148
, Issue.9
, pp. 1757-1769
-
-
Sarisky, R.T.1
Bacon, T.H.2
Boon, R.J.3
Duffy, K.E.4
Esser, K.M.5
Leary, J.6
Locke, L.A.7
Nguyen, T.T.8
Quail, M.R.9
Saltzman, R.10
-
41
-
-
0034111910
-
Difference in incidence of spontaneous mutations between herpes simplex virus types 1 and 2
-
DOI 10.1128/AAC.44.6.1524-1529.2000
-
R.T. Sarisky, T.T. Nguyen, K.E. Duffy, R.J. Wittrock, and J.J. Leary Difference in incidence of spontaneous mutations between herpes simplex virus types 1 and 2 Antimicrob. Agents Chemother. 44 2000 1524 1529 (Pubitemid 30340789)
-
(2000)
Antimicrobial Agents and Chemotherapy
, vol.44
, Issue.6
, pp. 1524-1529
-
-
Sarisky, R.T.1
Nguyen, T.T.2
Duffy, K.E.3
Wittrock, R.J.4
Leary, J.J.5
-
43
-
-
0023446348
-
The mutation rate and variability of eukaryotic viruses: An analytical review
-
D.B. Smith, and S.C. Inglis The mutation rate and variability of eukaryotic viruses: an analytical review J. Gen. Virol. 68 1987 2729 2740
-
(1987)
J. Gen. Virol.
, vol.68
, pp. 2729-2740
-
-
Smith, D.B.1
Inglis, S.C.2
-
44
-
-
0031846516
-
Inhibition of herpes simplex virus replication by a 2-amino thiazole via interactions with the helicase component of the UL5-UL8-UL52 complex
-
F.C. Spector, L. Liang, H. Giordano, M. Sivaraja, and M.G. Peterson Inhibition of herpes simplex virus replication by a 2-amino thiazole via interactions with the helicase component of the UL5-UL8-UL52 complex J. Virol. 72 1998 6979 6987 (Pubitemid 28377824)
-
(1998)
Journal of Virology
, vol.72
, Issue.9
, pp. 6979-6987
-
-
Spector, F.C.1
Liang, L.2
Giordano, H.3
Sivaraja, M.4
Peterson, M.G.5
-
45
-
-
77953536230
-
Mismatch primer-based PCR reveals that helicase-primase inhibitor resistance mutations pre-exist in herpes simplex virus type 1 clinical isolates and are not induced during incubation wth the inhibitor
-
S. Sukla, S. Biswas, A. Birkmann, P. Lischka, H. Zimmermann, and H.J. Field Mismatch primer-based PCR reveals that helicase-primase inhibitor resistance mutations pre-exist in herpes simplex virus type 1 clinical isolates and are not induced during incubation wth the inhibitor J. Antimicrob. Chemother. 65 2010 1347 1352
-
(2010)
J. Antimicrob. Chemother.
, vol.65
, pp. 1347-1352
-
-
Sukla, S.1
Biswas, S.2
Birkmann, A.3
Lischka, P.4
Zimmermann, H.5
Field, H.J.6
-
46
-
-
77953536608
-
Effects of therapy using a helicase-primase inhibitor (HPI) in mice infected with deliberate mixtures of wild-type HSV-1 and HPI-resistant UL5 mutant
-
S. Sukla, S. Biswas, A. Birkmann, P. Lischka, H. Ruebsamen-Schaeff, H. Zimmermann, and H.J. Field Effects of therapy using a helicase-primase inhibitor (HPI) in mice infected with deliberate mixtures of wild-type HSV-1 and HPI-resistant UL5 mutant Antivir. Res. 87 2010 67 73
-
(2010)
Antivir. Res.
, vol.87
, pp. 67-73
-
-
Sukla, S.1
Biswas, S.2
Birkmann, A.3
Lischka, P.4
Ruebsamen-Schaeff, H.5
Zimmermann, H.6
Field, H.J.7
-
47
-
-
79951955229
-
-
September 12-15, San Francisco, USA
-
H. Suzuki, K. Chono, K. Katsumata, M. Kobayashi, T. Kontani, K. Sudo, Y. Shimizu, and S. Takakura ASP2151, a novel helicase-primase inhibitor, possesses antiviral activity against varicella-zoster virus as well as herpes simplex virus type 1 and 2 Poster V-1741, Interscience Conference on Antimicrobial Agents and Chemotherapy September 12-15, San Francisco, USA 2009
-
(2009)
Poster V-1741, Interscience Conference on Antimicrobial Agents and Chemotherapy
-
-
Suzuki, H.1
Chono, K.2
Katsumata, K.3
Kobayashi, M.4
Kontani, T.5
Sudo, K.6
Shimizu, Y.7
Takakura, S.8
-
48
-
-
0031886971
-
Chronic vulvar ulceration in an immunocompetent woman due to acyclovir- resistant, thymidine kinase-deficient herpes simplex virus
-
S.M. Swetter, E.L. Hill, E.R. Kern, D.M. Koelle, C.M. Posaved, W. Laurence, and S. Safrin Chronic vulvar ulceration in an immunocompetent woman due to acyclovir-resistant thymidine kinase deficient herpes simplex virus J. Inf. Dis. 177 1997 543 550 (Pubitemid 28099865)
-
(1998)
Journal of Infectious Diseases
, vol.177
, Issue.3
, pp. 543-550
-
-
Swetter, S.M.1
Hill, E.L.2
Kern, E.R.3
Koelle, D.M.4
Posavad, C.M.5
Lawrence, W.6
Safrin, S.7
-
51
-
-
0026567670
-
The six conserved helicase motifs of the UL5 gene product, a component of the herpes simplex virus type 1 helicase primase, are essential for its function
-
L.A. Zhu, and S.K. Weller The six conserved helicase motifs of the UL5 gene product, a component of the herpes simplex virus type 1 helicase primase, are essential for its function J. Virol. 66 1992 469 479
-
(1992)
J. Virol.
, vol.66
, pp. 469-479
-
-
Zhu, L.A.1
Weller, S.K.2
|