Analysis of different complexes of type IIa sodium-dependent phosphate transporter in rat renal cortex using blue-native polyacrylamide gel electrophoresis

Journal of Medical Investigation

Volumn 58, Issue 1-2, 2011, Pages 140-147

  Tanimura, Ayako ^a   Yamada, Fumiyo ^a   Saito, Akihito ^b   Ito, Mikiko ^c   Kimura, Toru ^d   Anzai, Naohiko ^d   Horie, Daisuke ^a   Yamamoto, Hironori ^a   Miyamoto, Kenichi ^a   Taketani, Yutaka ^a   Takeda, Eiji ^a  

^a UNIVERSITY OF TOKUSHIMA   (Japan)

^b NIIGATA UNIVERSITY GRADUATE SCHOOL OF MEDICAL AND DENTAL SCIENCES   (Japan)

^c UNIVERSITY OF HYOGO   (Japan)

^d KYORIN UNIVERSITY   (Japan)

Author keywords

Macromolecular complex; Megalin; Native PAGE; NHERF1; PDZK1

Indexed keywords

EZRIN; MEGALIN; SODIUM PHOSPHATE COTRANSPORTER 2A;

ANIMAL CELL; ANIMAL TISSUE; APICAL MEMBRANE; ARTICLE; BLUE NATIVE POLYACRYLAMIDE GEL ELECTROPHORESIS; COMPLEX FORMATION; FLUORESCENCE MICROSCOPY; IMMUNOPRECIPITATION; KIDNEY CORTEX; KIDNEY TUBULE CELL; LIQUID CHROMATOGRAPHY; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN LOCALIZATION; RAT; TANDEM MASS SPECTROMETRY;

RATTUS;

EID: 79951920974     PISSN: 13431420     EISSN: None     Source Type: Journal    
DOI: 10.2152/jmi.58.140     Document Type: Article

References (35)

1. Capuano P, Bacic D, Stange G, Hernando N, Kaissling B, Pal R, Kocher O, Biber J, Wagner CA, Murer H: Expression and regulation of the renal Na/phosphate cotransporter NaPi-IIa in a mouse model deficient for the PDZ protein PDZK1. Pflugers Arch 449: 392-402, 2005
2. Wade JB, Liu J, Coleman RA, Cunningham R, Steplock DA, Lee-Kwon W, Pallone TL, Shenolikar S, Weinman EJ: Localization and interaction of NHERF isoforms in the renal proximal tubule of the mouse. Am J Physiol Cell Physiol 285: C1494-C1503, 2003
3. Hernando N, Gisler SM, Pribanic S, Déliot N, Capuano P, Wagner CA, Moe OW, Biber J, Murer H: NaPi-IIa and interacting partners. J Physiol 567: 21-26, 2005
4. Nashiki K, Taketani Y, Takeichi T, Sawada N, Yamamoto H, Ichikawa M, Arai H, Miyamoto K, Takeda E: Role of membrane microdomains in PTH-mediated down-regulation of NaPi-IIa in opossum kidney cells. Kidney Int 68: 1137-1147, 2005
5. Traebert M, Roth J, Biber J, Murer H, Kaissling B: Internalization of proximal tubular type II Na-Pi cotransporter by PTH: immunogold electron microscopy. Am J Physiol Renal Physiol 278: F148-F154, 2000
6. Bachmann S, Schlichting U, Geist B, Mutig K, Petsch T, Bacic D, Wagner CA, Kaissling B, Biber J, Murer H, Willnow TE: Kidney - specific inactivation of the megalin gene impairs trafficking of renal inorganic sodium phosphate co-transporter (NaPi-IIa). J Am Soc Nephrol 15: 892-900, 2004
7. Yamagata M, Ozono K, Hashimoto Y, Miyauchi Y, Kondou H, Michigami T: Intraperitoneal administration of recombinant receptor - associated protein causes phosphaturia via an alteration in subcellular distribution of the renal sodium phosphate co-transporter. J Am Soc Nephrol 16: 2338-2345, 2005
8. Minami H, Kim JR, Tada K, Takahashi F, Miyamoto K, Nakabou Y, Sakai K, Hagihira H: Inhibition of glucose absorption by phlorizin affects intestinal functions in rats. Gastroenterology 105: 692-697, 1993
9. Smart EJ, Ying YS, Mineo C, Anderson RG: A detergent-free method for purifying cavealae membrane from tissue culture cells. Proc Natl Acad Sci USA 92: 10104-10108, 1995
10. Katai K, Segawa H, Haga H, Morita K, Arai H, Tatsumi S, Taketani Y, Miyamoto K, Hisano S, Fukui Y, Takeda E: Acute regulation by dietary phosphate of the sodium-dependent phosphate transporter (NaP(i)- 2) in rat kidney. J Biochem 121: 50-55, 1997
11. Anzai N, Miyazaki H, Noshiro R, Khamdang S, Chairoungdua A, Shin HJ, Enomoto A, Sakamoto S, Hirata T, Tomita K, Kanai Y, Endou H: The multivalent PDZ domain-containing protein PDZK1 regulates transport activity of renal urate-anion exchanger URAT1 via its C terminus. J Biol Chem 279: 45942-45950, 2004
12. Hosaka K, Takeda T, Iino N, Hosojima M, Sato H, Kaseda R, Yamamoto K, Kobayashi A, Gejyo F, Saito A: Megalin and nonmuscle myosin heavy chain IIA interact with the adaptor protein Disabled-2 in proximal tubule cells. Kidney Int 75: 1308-1315, 2009
13. Perkins DN, Pappin DJ, Creasy DM, Cottrell JS: Probability-based protein identification by searching sequence databases using mass spec-trometry data. Electrophoresis 20: 3551-3567, 1999
14. Ito M, Iidawa S, Izuka M, Haito S, Segawa H, Kuwahata M, Ohkido I, Ohno H, Miyamoto K: Interaction of a farnesylated protein with renal type IIa Na/Pi co-transporter in response to parathyroid hormone and dietary phosphate. Biochem J 377: 607-616, 2004
15. Xiao Y, Boyer CJ, Vincent E, Dugré A, Vachon V, Potier M, Béliveau R: Involvement of disul-phide bonds in the renal sodium/phosphate co-transporter NaPi-2. Biochem J 15: 401-408, 1997
16. Hilpert J, Nykjaer A, Jacobsen C, Wallukat G, Nielsen R, Moestrup SK, Haller H, Luft FC, Christensen EI, Willnow TE: Megalin antagonizes activation of the parathyroid hormone receptor. J Biol Chem 274: 5620-5625, 1999
17. Nykjaer A, Dragun D, Walther D, Vorum H, Jacobsen C, Herz J, Melsen F, Christensen EI, Willnow TE: An endocytic pathway essential for renal uptake and activation of the steroid 25-(OH) vitamin D3. Cell 96: 507-515, 1999
18. Hammes A, Andreassen TK, Spoelgen R, Raila J, Hubner N, Schulz H, Metzger J, Schweigert FJ, Luppa PB, Nykjaer A, Willnow TE: Role of endocytosis in cellular uptake of sex steroids. Cell 122: 751-762, 2005
19. Saito A, Pietromonaco S, Loo AK, Farquhar MG: Complete cloning and sequencing of rat gp330/"megalin," a distinctive member of the low density lipoprotein receptor gene family. Proc Natl Acad Sci USA 91: 9725-9729, 1994
20. Christensen EI, Verroust PJ, Nielsen R: Receptor-mediated endocytosis in renal proximal tubule. Pflugers Arch 458: 1039 -1048, 2009
21. Bento-Abreu A, Velasco A, Polo-Hernandez E, Lillo C, Kozyraki R, Tabernero A, Medina JM: Albumin endocytosis via megalin in astrocytes is caveola- and Dab-1 dependent and is required for the synthesis of the neurotropic factor oleic acid. J Neurochem 111: 49-60, 2009
22. Biemesderfer D, DeGray B, Aronson PS: Active (9.6 s) and inactive (21 s) oligomers of NHE3 in microdomains of the renal brush border. J Biol Chem 276: 10161-10167, 2001
23. Li X, Galli T, Leu S, Wade JB, Weinman EJ, Leung G, Cheong A, Louvard D, Donowitz M: Na+-H+ exchanger 3 (NHE3) is present in lipid rafts in the rabbit ileal brush border: a role for rafts in trafficking and rapid stimulation of NHE3. J Physiol 537: 537-552, 2001
24. Inoue M, Digman MA, Cheng M, Breusegem SY, Halaihel N, Sorribas V, Mantulin WW, Gratton E, Barry NP, Levi M: Partitioning of NaPi cotransporter in cholesterol-, sphingo-myelin, and glycosphingolipid-enriched membrane domains modulates NaPi protein diffusion, clustering, and activity. J Biol Chem 279: 49160-49171, 2004
25. Murer H, Hernando N, Forster I, Biber J: Regulation of Na/Pi transporter in the proximal tubule. Annu Rev Physiol 65: 531-542, 2003
26. Palacín M, Kanai Y: The ancillary proteins of HATs: SLC3 family of amino acid transporters. Pflugers Arch 447: 490-494, 2004
27. Kwak JO, Kim HW, Jung SM, Song JH, Hong SB, Oh KJ, Ko CB, Cha SH: Co-localization and interaction of b0,+-type amino acid transporter 1 (BAT1) with caveolin-1 in rat kidney. J Nephrol 18: 681-689, 2005
28. Rodman JS, Kerjaschki D, Merisko E, Farquhar MG: Presence of an extensive clathrin coat on the apical plasmalemma of the rat kidney proximal tubule cell. J Cell Biol 98: 1630 -1636, 1984
29. Reczek D, Berryman M, Bretscher A: Identification of EBP50: A PDZ-containing phospho-protein that associates with members of the ezrin-radixin-moesin family. J Cell Biol 139: 169-179, 1997
30. Dudez T, Borot F, Huang S, Kwak BR, Bacchetta M, Ollero M, Stanton BA, Chanson M: CFTR in a lipid raft-TNFR1 complex modulates gap junctional intercellular communication and IL-8 secretion. Biochim Biophys Acta 1783:779-788, 2008
31. Wieczorek H, Brown D, Grinstein S, Ehrenfeld J, Harvey WR: Animal plasma membrane energization by proton-motive V-ATPases. Bioes-says 21: 637-648, 1999
32. Mineo C, Anderson RG: A vacuolar-type proton ATPase mediates acidification of plasmalem-mal vesicles during potocytosis. Exp Cell Res 224: 237-242, 1996
33. Boyer JC, Campbell CE, Sigurdson WJ, Kuo SM: Polarized localization of vitamin C transporters, SVCT1 and SVCT2, in epithelial cells. Biochem Biophys Res Commun 334: 150-156, 2005
34. Padányi R, Xiong Y, Antalffy G, Lór K, Pászty K, Strehler EE, Enyedi A: Apical scaffolding protein NHERF2 modulates the localization of alternatively spliced plasma membrane Ca2+ pump 2B variants in polarized epithelial cells. J Biol Chem 285: 31704-31712, 2010
35. Ikonen E: Roles of lipid rafts in membrane transport. Curr Opin Cell Biol 13: 470-477, 2001