Time-kill synergy tests of tigecycline combined with imipenem, amikacin, and ciprofloxacin against clinical isolates of multidrug-resistant Klebsiella pneumoniae and Escherichia coli

Annals of Clinical and Laboratory Science

Volumn 41, Issue 1, 2011, Pages 39-43

  Yim, Haejun ^a   Woo, Heungjeong ^a   Song, Wonkeun ^a   Park, Min Jeong ^a   Kim, Hyun Soo ^a   Lee, Kyu Man ^a   Hur, Jun ^a   Park, Man Seung ^a  

^a Hallym University Medical Center   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

AMIKACIN; BETA LACTAMASE AMPC; CEFEPIME; CEFOTAXIME; CEFTAZIDIME; CIPROFLOXACIN; EXTENDED SPECTRUM BETA LACTAMASE; IMIPENEM; TIGECYCLINE;

ARTICLE; BACTERIUM ISOLATE; BROTH DILUTION; DRUG POTENCY; DRUG POTENTIATION; ESCHERICHIA COLI; KLEBSIELLA PNEUMONIAE; MINIMUM INHIBITORY CONCENTRATION; MULTIDRUG RESISTANCE; NONHUMAN; PRIORITY JOURNAL; TIME KILL SYNERGY TEST;

AMIKACIN; BACTERIAL PROTEINS; BETA-LACTAMASES; CIPROFLOXACIN; DRUG RESISTANCE, MULTIPLE, BACTERIAL; DRUG SYNERGISM; ESCHERICHIA COLI; HUMANS; IMIPENEM; KLEBSIELLA PNEUMONIAE; MICROBIAL SENSITIVITY TESTS; MINOCYCLINE;

ESCHERICHIA COLI; KLEBSIELLA PNEUMONIAE;

EID: 79951912843     PISSN: 00917370     EISSN: 15508080     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. Paterson DL. Resistance in gram-negative bacteria: Enterobacteriaceae. Am J Infect Control 2006; 34(Suppl 1):S20-S28.
2. Baudry PJ, Nichol K, DeCorby M, Mataseje L, Mulvey MR, Hoban DJ, Zhanel GG. Comparison of antimicrobial resistance profiles among extended-spectrum- β-lactamase-producing and acquired AmpC β-lactamase-producing Escherichia coli isolates from Canadian intensive care units. Antimicrob Agents Chemother 2008;52:1864-1869.
3. Potz NA, Hope R, Warner M, Johnson AP, Livermore DM. Prevalence and mechanisms of cephalosporin resistance in Enterobacteriaceae in London and South-East England. J Antimicrob Chemother 2006;58:32032-32036.
4. Woodford N, Reddy S, Fagan EJ, Hill RL, Hopkins KL, Kaufmann ME, Kistler J, Palepou MF, Pike R, Ward ME, Cheesbrough J, Livermore DM. Wide geographic spread of diverse acquired β-lactamases among Escherichia coli and Klebsiella spp. in the UK and Ireland. J Antimicrob Chemother 2007;59:102-105.
5. Hoban DJ, Bouchillon SK, Dowzicky MJ. Antimicrobial susceptibility of extended-spectrum β-lactamase producers and multidrug-resistant Acinetobacter baumannii throughout the United States and comparative in vitro activity of tigecycline, a new glycycline antimicrobial. Diagn Microbiol Infect Dis 2007;57:423-428.
6. Souli M, Kontopidou FV, Koratzanis E, Antoniadou A, Giannitsioti E, Evangelopoulou P, Kannavaki S, Giamarellou H. In vitro activity of tigecycline against multi-drug-resistant, including pan-resistant, gram-negative and gram-positive clinical isolates from Greek hospitals. Antimicrob Agents Chemother 2006;50:3166-3169.
7. Mullangi PK, Pankey GA. Tigecycline in critical care. Crit Care Clin 2008;24:365-75. (Pubitemid 351400620)
8. Milatovic D, Schmitz FJ, Verhoef J, Fluit AC. Activities of the glycycline tigecycline (GAR-936) against 1,924 recent European clinical bacterial isolates. Antimicrob Agents Chemother 2003; 47:400-404. (Pubitemid 36070396)
9. Nathisuwan S, Burgess DS, Lewis JS II. Extended-spectrum β-lactamases: epidemiology, detection, and treatment. Pharmacotherapy. 2001; 21:920-928. (Pubitemid 32747312)
10. Ryoo NH, Kim EC, Hong SG, Park YJ, Lee K, Bae IK, Song EH, Jeong SH. Dissemination of SHV-12 and CTX-M-type extended-spectrum β-lactamases among clinical isolates of Escherichia coli and Klebsiella pneumoniae and emergence of GES-3 in Korea. J Antimicrob Chemother 2005;56: 698-702. (Pubitemid 41487771)
11. Perez-Perez FJ, Hanson ND. Detection of plasmid-mediated AmpC β-lactamase genes in clinical isolates by using multiplex PCR. J Clin Microbiol 2002;40: 2153-2162. (Pubitemid 34596400)
12. Song W, Kim JS, Kim HS, Yong D, Jeong SH, Park MJ, Lee KM. Increasing trend in the presence of plasmid-mediated AmpC β-lactamases in Enterobacteriaceae lacking chromosomal ampC gene at a Korean university hospital from 2002 to 2004. Diagn Microbiol Infect Dis 2006;55:219-224.
13. Clinical and Laboratory Standards Institute. Methods for dilution antimicrobial susceptibility tests for bacteria grow aerobically: approved standard M7-A7. CLSI 2007; Wayne, PA.
14. Vidaillac C, Leonard SN, Sader HS, Jones RN, Rybak MJ. In vitro activity of ceftaroline alone and in combination against clinical isolates of resistant gram-negative pathogens, including β-lactamase-producing Enterobacteriaceae and Pseudomonas aeruginosa. Antimicrob Agents Chemother 2009; 53:2360-2366.
15. Conejo MC, Hernandez JR, Pascual A. Effect of porin loss on the activity of tigecycline against Klebsiella pneumoniae producing extended-spectrum β-lactamases or plasmid-mediated AmpC-type β-lactamases. Diagn Microbiol Infect Dis 2008;61:343-345.
16. Jones CH, Tuckman M, Keeney D, Ruzin A, Bradford PA. Characterization and sequence analysis of extended-spectrum β-lactamase-encoding genes from Escherichia coli, Klebsiella pneumoniae, and Proteus mirabilis isolates collected during tigecycline phase 3 clinical trials. Antimicrob Agents Chemother 2009;53:465-475.
17. Kotapati S, Kuti JL, Nightingale CH, Nicolau DP. Clinical implications of extended-spectrum β-lactamase (ESBL) producing Klebsiella species and Escherichia coli on cefepime effectiveness. J Infect 2005;51:211-217. (Pubitemid 41554829)
18. Pai H, Kang CI, Byeon JH, Lee KD, Park WB, Kim HB, Kim EC, Oh MD, Choe KW. Epidemiology and clinical features of bloodstream infections caused by AmpC-type-β-lactamase producing Klebsiella pneumoniae. Antimicrob Agents Chemother 2004;48:3720-3728. (Pubitemid 39304595)
19. Bouza E, Munoz P. Monotherapy versus combination therapy for bacterial infections. Med Clin North Am 2000;84:1357-1389.
20. Cha R. In vitro activity of cefepime, imipenem, tigecycline, and gentamicin, alone and in combination, against extended-spectrum β-lactamase-producing Klebsiella pneumoniae and Escherichia coli. Pharmacotherapy 2008;28:295-300. (Pubitemid 351328901)
21. Lee K, Chong Y, Shin HB, Kim YA, Yong D, Yum JH. Modified Hodge and EDTA-disk synergy tests to screen metallo-β-lactamase-producing strains of Pseudomonas and Acinetobacter species. Clin Microbiol Infect 2001;7:88-91. (Pubitemid 34960278)