Polymorphisms in the CD36/FAT gene are associated with plasma vitamin E concentrations in humans

American Journal of Clinical Nutrition

Volumn 93, Issue 3, 2011, Pages 644-651

  Lecompte, Sophie ^a   De Edelenyi, Fabien Szabo ^b,c,d   Goumidi, Louisa ^a   Maiani, Giuseppe ^e   Moschonis, George ^f   Widhalm, Kurt ^g   Molnár, Dénes ^h   Kafatos, Anthony ⁱ   Spinneker, Andre ^j   Breidenassel, Christina ^j   Dallongeville, Jean ^a   Meirhaeghe, Aline ^a   Borel, Patrick ^b,c,d  

^a UNIV LILLE   (France)

^b INSERM   (France)

^c INSERM   (France)

^d AIX MARSEILLE UNIVERSITY   (France)

^e ISTITUTO NAZIONALE DELLA NUTRIZIONE   (Italy)

^f HAROKOPIO UNIVERSITY   (Greece)

^g MEDICAL UNIVERSITY OF VIENNA   (Austria)

^h UNIVERSITY OF PÉCS   (Hungary)

ⁱ UNIVERSITY OF CRETE   (Greece)

^j UNIVERSITY OF BONN   (Germany)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA TOCOPHEROL; CD36 ANTIGEN; POLYUNSATURATED FATTY ACID; TRIACYLGLYCEROL;

ADULT; ARTICLE; FATTY ACID BLOOD LEVEL; FEMALE; GENETIC POLYMORPHISM; GENOTYPE; HAPLOTYPE; HUMAN; HUMAN TISSUE; MALE; SINGLE NUCLEOTIDE POLYMORPHISM; TRIACYLGLYCEROL BLOOD LEVEL; VITAMIN BLOOD LEVEL;

EID: 79951908979     PISSN: 00029165     EISSN: 19383207     Source Type: Journal    
DOI: 10.3945/ajcn.110.004176     Document Type: Article

References (52)

1. Meier R, Tomizaki T, Schulze-Briese C, Baumann U, Stocker A. The molecular basis of vitamin E retention: structure of human alpha-tocopherol transfer protein. J Mol Biol 2003;331:725-34. (Pubitemid 36937156)
2. Landes N, Pfluger P, Kluth D, et al. Vitamin E activates gene expression via the pregnane X receptor. Biochem Pharmacol 2003;65:269-73. (Pubitemid 36015829)
3. Jervis KM, Robaire B. The effects of long-term vitamin E treatment on gene expression and oxidative stress damage in the aging Brown Norway rat epididymis. Biol Reprod 2004;71:1088-95. (Pubitemid 39249791)
4. Roy S, Lado BH, Khanna S, Sen CK. Vitamin E sensitive genes in the developing rat fetal brain: a high-density oligonucleotide microarray analysis. FEBS Lett 2002;530:17-23. (Pubitemid 35248179)
5. Chojkier M, Houglum K, Lee KS, Buck M. Long- and short-term D-alpha-tocopherol supplementation inhibits liver collagen alpha1(I) gene expression. Am J Physiol 1998;275:G1480-5.
6. Landrier JF, Gouranton E, El Yazidi C, et al. Adiponectin expression is induced by vitamin E via a peroxisome proliferator-activated receptor gamma-dependent mechanism. Endocrinology 2009;150:5318-25.
7. Landrier JF, Gouranton E, Reboul E, et al. Vitamin E decreases endogenous cholesterol synthesis and apo-AI-mediated cholesterol secretion in Caco-2 cells. J Nutr Biochem 2010;21:1207-13.
8. Pryor WA. Vitamin E and heart disease: basic science to clinical intervention trials. Free Radic Biol Med 2000;28:141-64. (Pubitemid 30045582)
9. Yusuf S, Phil D, Dagenais G, Pogue J, Bosch J, Sleight P. Vitamin E supplementation and cardiovascular events in high-risk patients. N Engl J Med 2000;342:154-60. (Pubitemid 30051646)
10. van der Loo B, Labugger R, Aebischer CP, et al. Cardiovascular aging is associated with vitamin E increase. Circulation 2002;105:1635-8. (Pubitemid 34298604)
11. Miller ER III, Pastor-Barriuso R, Dalal D, Riemersma RA, Appel LJ, Guallar E. Meta-analysis: high-dosage vitamin E supplementation may increase all-cause mortality. Ann Intern Med 2005;142:37-46.
12. Romanchik JE, Morel DW, Harrison EH. Distributions of carotenoids and alpha-tocopherol among lipoproteins do not change when human plasma is incubated in vitro. J Nutr 1995;125:2610-7.
13. Reboul E, Trompier D, Moussa M, et al. ATP-binding cassette transporter A1 is significantly involved in the intestinal absorption of alphaand gamma-tocopherol but not in that of retinyl palmitate in mice. Am J Clin Nutr 2009;89:177-84.
14. Mardones P, Strobel P, Miranda S, et al. Alpha-tocopherol metabolism is abnormal in scavenger receptor class B type I (SR-BI)-deficient mice. J Nutr 2002;132:443-9. (Pubitemid 34208747)
15. Holloway GP, Jain SS, Bezaire V, et al. FAT/CD36-null mice reveal that mitochondrial FAT/CD36 is required to upregulate mitochondrial fatty acid oxidation in contracting muscle. Am J Physiol Regul Integr Comp Physiol 2009;297:R960-7.
16. Holloway GP, Luiken JJ, Glatz JF, Spriet LL, Bonen A. Contribution of FAT/CD36 to the regulation of skeletal muscle fatty acid oxidation: an overview. Acta Physiol (Oxf) 2008;194:293-309.
17. Silverstein RL, Febbraio M. CD36, a scavenger receptor involved in immunity, metabolism, angiogenesis, and behavior. Sci Signal 2009;2:re3.
18. Bruno RS, Traber MG. Cigarette smoke alters human vitamin E requirements. J Nutr 2005;135:671-4. (Pubitemid 40464086)
19. Gomez-Coronado D, Entrala A, Alvarez JJ, et al. Influence of apolipoprotein E polymorphism on plasma vitamin A and vitamin E levels. Eur J Clin Invest 2002;32:251-8. (Pubitemid 36216590)
20. Doring F, Rimbach G, Lodge JK. In silico search for single nucleotide polymorphisms in genes important in vitamin E homeostasis. IUBMB Life 2004;56:615-20.
21. Zingg JM, Azzi A, Meydani M. Genetic polymorphisms as determinants for disease-preventive effects of vitamin E. Nutr Rev 2008;66:406-14. (Pubitemid 352000151)
22. Borel P, Moussa M, Reboul E, et al. Human plasma levels of vitamin E and carotenoids are associated with genetic polymorphisms in genes involved in lipid metabolism. J Nutr 2007;137:2653-9. (Pubitemid 350255293)
23. Borel P, Moussa M, Reboul E, et al. Human fasting plasma concentrations of vitamin E and carotenoids, and their association with genetic variants in apo C-III, cholesteryl ester transfer protein, hepatic lipase, intestinal fatty acid binding protein and microsomal triacylglycerol transfer protein. Br J Nutr 2009;101:680-7.
24. Girona J, Guardiola M, Cabre A, et al. The apolipoprotein A5 gene -1131T→C polymorphism affects vitamin E plasma concentrations in type 2 diabetic patients. Clin Chem Lab Med 2008;46:453-7. (Pubitemid 351820367)
25. Wright ME, Peters U, Gunter MJ, et al. Association of variants in two vitamin E transport genes with circulating vitamin e concentrations and prostate cancer risk. Cancer Res 2009;69:1429-38.
26. Ferrucci L, Perry JR, Matteini A, et al. Common variation in the beta-carotene 15,15′-monooxygenase 1 gene affects circulating levels of carotenoids: a genome-wide association study. Am J Hum Genet 2009;84:123-33.
27. Guardiola M, Ribalta J, Gomez-Coronado D, Lasuncion MA, de Oya M, Garces C. The apolipoprotein A5 (APOA5) gene predisposes Caucasian children to elevated triglycerides and vitamin E (Four Provinces Study). Atherosclerosis 2010;212:543-7.
28. Vazquez Martinez C, Galan P, Preziosi P, Ribas L, Serra LL, Hercberg S. [The SUVIMAX (France) study: the role of antioxidants in the prevention of cancer and cardiovascular disorders.] Rev Esp Salud Publica 1998;72:173-83 (in Spanish).
29. Moreno LA, De Henauw S, González-Gross M, et al. Design and implementation of the Healthy Lifestyle in Europe by Nutrition in Adolescence Cross-Sectional Study. Int J Obes (Lond) 2008;32(suppl 5):S4-11.
30. Hercberg S, Galan P, Preziosi P, et al. The SU.VI.MAX Study: a randomized, placebo-controlled trial of the health effects of antioxidant vitamins and minerals. Arch Intern Med 2004;164:2335-42. (Pubitemid 39532244)
31. Ma X, Bacci S, Mlynarski W, et al. A common haplotype at the CD36 locus is associated with high free fatty acid levels and increased cardiovascular risk in Caucasians. Hum Mol Genet 2004;13:2197-205. (Pubitemid 39359920)
32. Corpeleijn E, van der Kallen CJ, Kruijshoop M, et al. Direct association of a promoter polymorphism in the CD36/FAT fatty acid transporter gene with Type 2 diabetes mellitus and insulin resistance. Diabet Med 2006;23:907-11. (Pubitemid 44141081)
33. De la Vega FM, Lazaruk KD, Rhodes MD, Wenz MH. Assessment of two flexible and compatible SNP genotyping platforms: TaqMan SNP genotyping assays and the SNPlex Genotyping System. Mutat Res 2005;573:111-35. (Pubitemid 40514403)
34. Tobler AR, Short S, Andersen MR, et al. The SNPlex genotyping system: a flexible and scalable platform for SNP genotyping. J Biomol Tech 2005;16:398-406.
35. Bokor S, Dumont J, Spinneker A, et al. Single nucleotide polymorphisms in the FADS gene cluster are associated with delta-5 and delta-6 desaturase activities estimated by serum fatty acid ratios. J Lipid Res 2010;51:2325-33.
36. Tregouet DA, Garelle V. A new JAVA interface implementation of THESIAS: testing haplotype effects in association studies. Bioinformatics 2007;23:1038-9. (Pubitemid 47050595)
37. Tregouet DA, Konig IR, Erdmann J, et al. Genome-wide haplotype association study identifies the SLC22A3-LPAL2-LPA gene cluster as a risk locus for coronary artery disease. Nat Genet 2009;41:283-5.
38. Akaike H. A new look at the statistical model identification. IEEE Trans Automat Contr 1974;19:716-23.
39. Bokor S, Legry V, Meirhaeghe A, et al. Single-nucleotide polymorphism of CD36 locus and obesity in European adolescents. Obesity (Silver Spring) 2009;18:1398-403.
40. Devaraj S, Hugou I, Jialal I. Alpha-tocopherol decreases CD36 expression in human monocyte-derived macrophages. J Lipid Res 2001;42:521-7. (Pubitemid 32366994)
41. Ricciarelli R, Zingg JM, Azzi A. Vitamin E reduces the uptake of oxidized LDL by inhibiting CD36 scavenger receptor expression in cultured aortic smooth muscle cells. Circulation 2000;102:82-7. (Pubitemid 30430557)
42. Munteanu A, Zingg JM, Ricciarelli R, Azzi A. CD36 overexpression in ritonavir-treated THP-1 cells is reversed by alpha-tocopherol. Free Radic Biol Med 2005;38:1047-56. (Pubitemid 40386551)
43. Ozer NK, Negis Y, Aytan N, et al. Vitamin E inhibits CD36 scavenger receptor expression in hypercholesterolemic rabbits. Atherosclerosis 2006;184:15-20. (Pubitemid 41721064)
44. Drover VA, Nguyen DV, Bastie CC, et al. CD36 mediates both cellular uptake of very long chain fatty acids and their intestinal absorption in mice. J Biol Chem 2008;283:13108-15.
45. Nassir F, Wilson B, Han X, Gross RW, Abumrad NA. CD36 is important for fatty acid and cholesterol uptake by the proximal but not distal intestine. J Biol Chem 2007;282:19493-501. (Pubitemid 47100088)
46. Coburn CT, Knapp FF Jr, Febbraio M, Beets AL, Silverstein RL, Abumrad NA. Defective uptake and utilization of long chain fatty acids in muscle and adipose tissues of CD36 knockout mice. J Biol Chem 2000;275:32523-9.
47. Febbraio M, Abumrad NA, Hajjar DP, et al. A null mutation in murine CD36 reveals an important role in fatty acid and lipoprotein metabolism. J Biol Chem 1999;274:19055-62.
48. van Bennekum A, Werder M, Thuahnai ST, et al. Class B scavenger receptor-mediated intestinal absorption of dietary beta-carotene and cholesterol. Biochemistry 2005;44:4517-25. (Pubitemid 40403994)
49. Borel P. Factors affecting intestinal absorption of highly lipophilic food microconstituents (fat-soluble vitamins, carotenoids and phytosterols). Clin Chem Lab Med 2003;41:979-94. (Pubitemid 37062987)
50. Reboul E, Klein A, Bietrix F, et al. Scavenger receptor class B type I (SR-BI) is involved in vitamin E transport across the enterocyte. J Biol Chem 2006;281:4739-45. (Pubitemid 43847734)
51. Love-Gregory L, Sherva R, Schappe T, et al. Common CD36 SNPs reduce protein expression and may contribute to a protective atherogenic profile. Hum Mol Genet 2010;20:193-201.
52. Traber MG, Atkinson J. Vitamin E, antioxidant and nothing more. Free Radic Biol Med 2007;43:4-15.