Minimally-invasive fetal autopsy using magnetic resonance imaging and percutaneous organ biopsies: Clinical value and comparison to conventional autopsy

Ultrasound in Obstetrics and Gynecology

Volumn 37, Issue 3, 2011, Pages 317-323

  Breeze, A C G ^a   Jessop, F A ^a   Set, P A K ^a   Whitehead, A L ^a   Cross, J J ^a   Lomas, D J ^a,b   Hackett, G A ^a   Joubert, I ^a   Lees, C C ^a  

^a ADDENBROOKE S HOSPITAL   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Congenital abnormality; Fetal death; MRI; Needle biopsy; Postmortem imaging; Prenatal ultrasound; Stillbirth; Termination of pregnancy

Indexed keywords

ARTICLE; AUTOPSY; BIOPSY; BRAIN; COMPARATIVE STUDY; FEMALE; FETUS; HUMAN; LIVER; LUNG; METHODOLOGY; NUCLEAR MAGNETIC RESONANCE IMAGING; OBSERVER VARIATION; ORGAN SIZE; PATHOLOGY; PREGNANCY; PRENATAL DEVELOPMENT;

AUTOPSY; BIOPSY; BRAIN; FEMALE; FETUS; HUMANS; LIVER; LUNG; MAGNETIC RESONANCE IMAGING; OBSERVER VARIATION; ORGAN SIZE; PREGNANCY;

EID: 79951900666     PISSN: 09607692     EISSN: 14690705     Source Type: Journal    
DOI: 10.1002/uog.8844     Document Type: Article

References (27)

1. Confidential Enquiry into Maternal and Child Heath (CEMACH). Perinatal Mortality 2007. Confidential Enquiry into Maternal and Child Health: London, UK, 2009.
2. Ahman E, Zupan J. Neonatal and Perinatal Mortality. Country, Regional and Global Estimates 2004. WHO: Geneva, Switzerland, 2007.
3. Silver RM. Fetal death. Obstet Gynecol 2007; 109: : 153-167. (Pubitemid 46035521)
4. Boyd PA, Tondi F, Hicks NR, Chamberlain PF. Autopsy after termination of pregnancy for fetal anomaly: retrospective cohort study. BMJ 2004; 328: 137-140. (Pubitemid 38117460)
5. Gordijn SJ, Erwich JJ, Khong TY. The perinatal autopsy: pertinent issues in multicultural Western Europe. Eur J Obstet Gynecol Reprod Biol 2007; 132: 3-7. (Pubitemid 46635973)
6. Rose C, Evans M, Tooley J. Falling rates of perinatal postmortem examination: are we to blame? Arch Dis Child Fetal Neonatal Ed 2006; 91: F465. (Pubitemid 44701868)
7. Snowdon C, Elbourne DR, Garcia J. Perinatal pathology in the context of a clinical trial: attitudes of neonatologists and pathologists. Arch Dis Child Fetal Neonatal Ed 2004; 89: F204-F207. (Pubitemid 38570146)
8. Sebire NJ. Towards the minimally invasive autopsy? Ultrasound Obstet Gynecol 2006; 28: 865-867. (Pubitemid 46025201)
9. Breeze AC, Gallagher FA, Lomas DJ, Smith GC, Lees CC. Postmortem fetal organ volumetry using magnetic resonance imaging and comparison to organ weights at conventional autopsy. Ultrasound Obstet Gynecol 2008; 31: 187-193.
10. Thayyil S, Schievano S, Robertson NJ, Jones R, Chitty LS, Sebire NJ, Taylor AM. A semi-automated method for non-invasive internal organ weight estimation by post-mortem magnetic resonance imaging in fetuses, newborns and children. Eur J Radiol 2009; 72: 321-326.
11. Nicholl RM, Balasubramaniam VP, Urquhart DS, Sellathurai N, Rutherford MA. Postmortem brain MRI with selective tissue biopsy as an adjunct to autopsy following neonatal encephalopathy. Eur J Paediatr Neurol 2007; 11: 167-174. (Pubitemid 46591150)
12. Breeze AC, Cross JJ, Hackett GA, Jessop FA, Joubert I, Lomas DJ, Set PA, Whitehead AL, Lees CC. Use of a confidence scale in reporting postmortem fetal magnetic resonance imaging. Ultrasound Obstet Gynecol 2006; 28: 918-924. (Pubitemid 46025210)
13. Breeze AC, Jessop FA, Whitehead AL, Set PA, Berman L, Hackett GA, Lees CC. Feasibility of percutaneous organ biopsy as part of a minimally invasive perinatal autopsy. Virchows Arch 2008; 452: 201-207.
14. Brookes JA, Hall-Craggs MA, Sams VR, Lees WR. Noninvasive perinatal necropsy by magnetic resonance imaging. Lancet 1996; 348: 1139-1141.
15. Thayyil S, Cleary JO, Sebire NJ, Scott RJ, Chong K, Gunny R, Owens CM, Olsen OE, Offiah AC, Parks HG, Chitty LS, Price AN, Yousry TA, Robertson NJ, Lythgoe MF, Taylor AM. Post-mortem examination of human fetuses: a comparison of whole-body high-field MRI at 9.4 T with conventional MRI and invasive autopsy. Lancet 2009; 374: 467-475.
16. Hagmann CF, Robertson NJ, Sams VR, Brookes JA. Postmortem magnetic resonance imaging as an adjunct to perinatal autopsy for renal-tract abnormalities. Arch Dis Child Fetal Neonatal Ed 2007; 92: F215-F219.
17. Alderliesten ME, Peringa J, van der Hulst VP, Blaauwgeers HL, van Lith JM. Perinatal mortality: clinical value of postmortem magnetic resonance imaging compared with autopsy in routine obstetric practice. BJOG 2003; 110: 378-382. (Pubitemid 36423212)
18. Woodward PJ, Sohaey R, Harris DP, Jackson GM, Klatt EC, Alexander AL, Kennedy A. Postmortem fetal MR imaging: comparison with findings at autopsy. AJR Am J Roentgenol 1997; 168: 41-46. (Pubitemid 27014744)
19. Griffiths PD, Variend D, Evans M, Jones A, Wilkinson ID, Paley MN, Whitby E. Postmortem MR imaging of the fetal and stillborn central nervous system. AJNR Am J Neuroradiol 2003; 24: 22-27. (Pubitemid 36110096)
20. Huisman TA, Wisser J, Stallmach T, Krestin GP, Huch R, Kubik-Huch RA. MR autopsy in fetuses. Fetal Diagn Ther 2002; 17: 58-64. (Pubitemid 34102563)
21. Saller DN Jr, Lesser KB, Harrel U, Rogers BB, Oyer CE. The clinical utility of the perinatal autopsy. JAMA 1995; 273: 663-665.
22. Faye-Petersen OM, Guinn DA, Wenstrom KD. Value of perinatal autopsy. Obstet Gynecol 1999; 94: 915-920.
23. Wright C, Lee RE. Investigating perinatal death: a review of the options when autopsy consent is refused. Arch Dis Child Fetal Neonatal Ed 2004; 89: F285-F288. (Pubitemid 38869663)
24. Dean AF, Whitby EH. Contribution of antenatal magnetic resonance imaging to diagnostic neuropathology. Curr Diagn Pathol 2007; 13: 171-179. (Pubitemid 46963006)
25. Griffiths PD, Paley MN, Whitby EH. MR imaging of the fetal brain and spine: a maturing technology. Ann Acad Med Singapore 2003; 32: 483-489. (Pubitemid 37214475)
26. Levine D, Barnes PD, Robertson RR, Wong G, Mehta TS. Fast MR imaging of fetal central nervous system abnormalities. Radiology 2003; 229: 51-61. (Pubitemid 37152104)
27. Griffiths PD, Paley MN, Whitby EH. Post-mortem MRI as an adjunct to fetal or neonatal autopsy. Lancet 2005; 365: 1271-1273. (Pubitemid 40469660)