Are we ready to use an early alternative end point as the primary end point of a phase III study in rectal cancer?

Journal of Clinical Oncology

Volumn 28, Issue 29, 2010, Pages

  Glynne Jones, Rob ^a,b   Sebag Montefiore, David ^a,b  

^a MOUNT VERNON HOSPITAL   (United Kingdom)

^b ST JAMES S UNIVERSITY HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CAPECITABINE; FLUOROURACIL; OXALIPLATIN;

CANCER RADIOTHERAPY; CANCER STAGING; CANCER SURVIVAL; DISEASE FREE SURVIVAL; DRUG EFFICACY; HISTOPATHOLOGY; HUMAN; LETTER; NUCLEAR MAGNETIC RESONANCE IMAGING; OUTCOME ASSESSMENT; OVERALL SURVIVAL; PATHOLOGICAL COMPLETE RESPONSE; PHASE 3 CLINICAL TRIAL (TOPIC); PRIORITY JOURNAL; QUALITY CONTROL; RADIOSENSITIZATION; RECTUM CANCER; RECTUM RESECTION; SAMPLE SIZE; TREATMENT OUTCOME; TREATMENT RESPONSE;

ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CHEMOTHERAPY, ADJUVANT; CLINICAL TRIALS, PHASE III AS TOPIC; COMBINED MODALITY THERAPY; DEOXYCYTIDINE; FLUOROURACIL; HUMANS; ORGANOPLATINUM COMPOUNDS; RADIOTHERAPY, ADJUVANT; RANDOMIZED CONTROLLED TRIALS AS TOPIC; RECTAL NEOPLASMS; TREATMENT OUTCOME;

EID: 79951878901     PISSN: 0732183X     EISSN: 15277755     Source Type: Journal    
DOI: 10.1200/JCO.2010.30.2067     Document Type: Letter

References (6)

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