메뉴 건너뛰기




Volumn 63, Issue 2, 2011, Pages 282-294

In vitro studies on the inhibition of colon cancer by butyrate and polyphenolic compounds

Author keywords

[No Author keywords available]

Indexed keywords

ALKALINE PHOSPHATASE; BUTYRIC ACID; CATECHIN; CHRYSIN; EPICATECHIN; MESSENGER RNA; MONOCARBOXYLATE TRANSPORTER 1; MYRICETIN; POLYPHENOL DERIVATIVE; QUERCETIN; RESVERATROL; XANTHOHUMOL;

EID: 79951877120     PISSN: 01635581     EISSN: None     Source Type: Journal    
DOI: 10.1080/01635581.2011.523166     Document Type: Article
Times cited : (43)

References (65)
  • 2
    • 50149095987 scopus 로고    scopus 로고
    • Diet and cancer prevention: The roles of observation and experimentation
    • Martínez ME, Marshall JR, and Giovannucci E: Diet and cancer prevention: the roles of observation and experimentation. Nat Rev Cancer 8, 694-703, 2008.
    • (2008) Nat Rev Cancer , vol.8 , pp. 694-703
    • Martínez, M.E.1    Marshall, J.R.2    Giovannucci, E.3
  • 3
    • 38949131470 scopus 로고    scopus 로고
    • Flavan-3-ols: Nature, occurrence and biological activity
    • DOI 10.1002/mnfr.200700137
    • Aron PM and Kennedy JA: Flavan-3-ols: nature, occurrence, and biological activity. Mol Nutr Food Res 52, 79-104, 2008. (Pubitemid 351211804)
    • (2008) Molecular Nutrition and Food Research , vol.52 , Issue.1 , pp. 79-104
    • Aron, P.M.1    Kennedy, J.A.2
  • 4
    • 66149149841 scopus 로고    scopus 로고
    • Green tea: Nature's defense against malignancies
    • Butt MS and Sultan MT: Green tea: nature's defense against malignancies. Crit Rev Food Sci Nutr 49, 463-473, 2009.
    • (2009) Crit Rev Food Sci Nutr , vol.49 , pp. 463-473
    • Butt, M.S.1    Sultan, M.T.2
  • 5
    • 0019128183 scopus 로고
    • Role of anaerobic bacteria in the metabolic welfare of the colonic mucosa in man
    • Roediger WE: Role of anaerobic bacteria in the metabolic welfare of the colonic mucosa in man. Gut 21, 793-798, 1980.
    • (1980) Gut , vol.21 , pp. 793-798
    • Roediger, W.E.1
  • 7
    • 0028859161 scopus 로고
    • Apoptosis in colorectal tumour cells: Induction by the short-chain fatty acids butyrate, propionate and acetate and by the bile salt deoxycholate
    • Hague A, Elder DJ, Hicks DJ, and Paraskeva C: Apoptosis in colorectal tumour cells: induction by the short-chain fatty acids butyrate, propionate and acetate and by the bile salt deoxycholate. Int J Cancer 60, 400-406, 1995.
    • (1995) Int J Cancer , vol.60 , pp. 400-406
    • Hague, A.1    Elder, D.J.2    Hicks, D.J.3    Paraskeva, C.4
  • 8
    • 0028286187 scopus 로고
    • Potentiation by specific short-chain fatty acids of differentiation and apoptosis in human colonic carcinoma cell lines
    • Heerdt BG, Houston MA, and Augenlicht LH: Potentiation by specific short-chain fatty acids of differentiation and apoptosis in human colonic carcinoma cell lines. Cancer Res 54, 3288-3293, 1994.
    • (1994) Cancer Res , vol.54 , pp. 3288-3293
    • Heerdt, B.G.1    Houston, M.A.2    Augenlicht, L.H.3
  • 10
    • 0020696321 scopus 로고
    • Stimulatory effect of short chain fatty acids on the epithelial cell proliferation in rat large intestine
    • DOI 10.1016/0300-9629(83)90631-X
    • Sakata T and von Engelhardt W: Stimulatory effect of short-chain fatty acids on the epithelial cell proliferation in rat large intestine. Comp Biochem Physiol 74A, 459-462, 1983. (Pubitemid 13143073)
    • (1983) Comparative Biochemistry and Physiology - A Physiology , vol.74 , Issue.2 , pp. 459-462
    • Sakata, T.1    Von, E.W.2
  • 11
    • 35448975276 scopus 로고    scopus 로고
    • Anion absorption in the intestine: Anion transporters, short chain fatty acids, and role of the DRA gene product
    • Montrose MH and Kere J: Anion absorption in the intestine: anion transporters, short chain fatty acids, and role of the DRA gene product. Curr Top Membr Transp 50, 301-328, 2001.
    • (2001) Curr Top Membr Transp , vol.50 , pp. 301-328
    • Montrose, M.H.1    Kere, J.2
  • 12
    • 0024562962 scopus 로고
    • Short-chain fatty acids stimulate active sodium and chloride absorption in vitro in the rat distal colon
    • Binder HJ and Mehta P: Short-chain fatty acids stimulate Na and Cl absorption in vitro in the rat distal colon. Gastroenterology 96, 989-996, 1989. (Pubitemid 19091111)
    • (1989) Gastroenterology , vol.96 , Issue.4 , pp. 989-996
    • Binder, H.J.1    Mehta, P.2
  • 16
    • 30644463203 scopus 로고    scopus 로고
    • Microarray analysis of butyrate regulated genes in colonic epithelial cells
    • DOI 10.1089/dna.2006.25.49
    • Daly K and Shirazi-Beechey SP: Microarray analysis of butyrate regulated genes in colonic epithelial cells. DNA Cell Biol 25, 49-62, 2006. (Pubitemid 43089752)
    • (2006) DNA and Cell Biology , vol.25 , Issue.1 , pp. 49-62
    • Daly, K.1    Shirazi-Beechey, S.P.2
  • 17
    • 0036252352 scopus 로고    scopus 로고
    • The effects of short-chain fatty acids on human colon cancer cell phenotype are associated with histone hyperacetylation
    • Hinnebusch BF, Meng S, Wu JT, Archer SY, and Hodin RA: The effects of short-chain fatty acids on human colon cancer cell phenotype are associated with histone hyperacetylation. J Nutr 132, 1012-1017, 2002. (Pubitemid 34493567)
    • (2002) Journal of Nutrition , vol.132 , Issue.5 , pp. 1012-1017
    • Hinnebusch, B.F.1    Meng, S.2    Wu, J.T.3    Archer, S.Y.4    Hodin, R.A.5
  • 18
    • 53749107434 scopus 로고    scopus 로고
    • Overview of the proton-coupled MCT (SLC16A) family of transporters: Characterization, function and role in the transport of the drug of abuse gamma-hydroxybutyric acid
    • Morris ME and Felmlee MA: Overview of the proton-coupled MCT (SLC16A) family of transporters: characterization, function and role in the transport of the drug of abuse gamma-hydroxybutyric acid. AAPS J 10, 311-321, 2008.
    • (2008) AAPS J , vol.10 , pp. 311-321
    • Morris, M.E.1    Felmlee, M.A.2
  • 19
    • 1242340302 scopus 로고    scopus 로고
    • The SLC16 gene family - From monocarboxylate transporters (MCTs) to aromatic amino acid transporters and beyond
    • DOI 10.1007/s00424-003-1067-2, The ABCs of Solute Carriers: Physiological, Pathological and Therapeutic Implications of Human Membrane Transport Proteins
    • Halestrap AP and Meredith D: The SLC16 gene family - from monocarboxylate transporters (MCTs) to aromatic amino acid transporters and beyond. Pflugers Arch-Eur J Physiol 447, 619-628, 2004. (Pubitemid 38241446)
    • (2004) Pflugers Archiv European Journal of Physiology , vol.447 , Issue.5 , pp. 619-628
    • Halestrap, A.P.1    Meredith, D.2
  • 20
    • 33645969256 scopus 로고    scopus 로고
    • SLC5A8 (SMCT1)-mediated transport of butyrate forms the basis for the tumor suppressive function of the transporter
    • Gupta N, Martin PM, Prasad PD, and Ganapathy V: SLC5A8 (SMCT1)-mediated transport of butyrate forms the basis for the tumor suppressive function of the transporter. Life Sci 78, 2419-2425, 2006.
    • (2006) Life Sci , vol.78 , pp. 2419-2425
    • Gupta, N.1    Martin, P.M.2    Prasad, P.D.3    Ganapathy, V.4
  • 21
    • 15744394434 scopus 로고    scopus 로고
    • The human colonic monocarboxylate transporter isoform 1: Its potential importance to colonic tissue homeostasis
    • DOI 10.1053/j.gastro.2004.12.003
    • Cuff M, Dyer J, Jones M, and Shirazi-Beechey S: The human colonic monocarboxylate transporter isoform 1: its potential importance to colonic tissue homeostasis. Gastroenterology 128, 676-686, 2005. (Pubitemid 40585370)
    • (2005) Gastroenterology , vol.128 , Issue.3 , pp. 676-686
    • Cuff, M.1    Dyer, J.2    Jones, M.3    Shirazi-Beechey, S.4
  • 22
    • 35848970970 scopus 로고    scopus 로고
    • Inhibition effect of flavonoids on monocarboxylate transporter 1 (MCT1) in Caco-2 cells
    • Shim CK, Cheon EP, Kang KW, Seo KS, and Han HK: Inhibition effect of flavonoids on monocarboxylate transporter 1 (MCT1) in Caco-2 cells. J Pharm Pharmacol 59, 1515-1519, 2007.
    • (2007) J Pharm Pharmacol , vol.59 , pp. 1515-1519
    • Shim, C.K.1    Cheon, E.P.2    Kang, K.W.3    Seo, K.S.4    Han, H.K.5
  • 23
    • 33846469955 scopus 로고    scopus 로고
    • Flavonoids modulate monocarboxylate transporter-1-mediated transport of gamma-hydroxybutyrate in vitro and in vivo
    • DOI 10.1124/dmd.106.012369
    • Wang Q and Morris ME: Flavonoids modulate monocarboxylate transporter-1-mediated transport of gamma-hydroxybutyrate in vitro and in vivo. Drug Metab Dispos 35, 201-208, 2007. (Pubitemid 46151668)
    • (2007) Drug Metabolism and Disposition , vol.35 , Issue.2 , pp. 201-208
    • Wang, Q.1    Morris, M.E.2
  • 24
    • 0344629767 scopus 로고    scopus 로고
    • Tea polyphenols inhibit the transport of dietary phenolic acids mediated by the monocarboxylic acid transporter (MCT) in intestinal Caco-2 cell monolayers
    • Konishi Y, Kobayashi S, and Shimizu M: Tea polyphenols inhibit the transport of dietary phenolic acids mediated by the monocarboxylic acid transporter (MCT) in intestinal Caco-2 cell monolayers. J Agric Food Chem 51, 7296-7302, 2003.
    • (2003) J Agric Food Chem , vol.51 , pp. 7296-7302
    • Konishi, Y.1    Kobayashi, S.2    Shimizu, M.3
  • 25
    • 0142241274 scopus 로고    scopus 로고
    • Cellular Uptake and Efflux of the Tea Flavonoid (-)-Epicatechin-3-gallate in the Human Intestinal Cell Line Caco-2
    • DOI 10.1124/jpet.103.054296
    • Vaidyanathan JB and Walle T: Cellular uptake and efflux of the tea flavonoid (-)epicatechin-3-gallate in the human intestinal cell line Caco-2. J Pharmacol Exp Ther 307, 745-752, 2003. (Pubitemid 37310692)
    • (2003) Journal of Pharmacology and Experimental Therapeutics , vol.307 , Issue.2 , pp. 745-752
    • Vaidyanathan, J.B.1    Walle, T.2
  • 26
    • 0018649222 scopus 로고
    • Inhibition of lactate transport and glycolysis in Ehrlich ascites tumor cells by bioflavonoids
    • Belt JA, Thomas JA, Buchsbaum RN, and Racker E: Inhibition of lactate transport and glycolysis in Ehrlich ascites tumor cells by bioflavonoids. Biochemistry 18, 3506-3511, 1979. (Pubitemid 9255089)
    • (1979) Biochemistry , vol.18 , Issue.16 , pp. 3506-3511
    • Belt, J.A.1    Thomas, J.A.2    Buchsbaum, R.N.3    Racker, E.4
  • 27
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
    • Mosmann T: Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 65, 55-63, 1983.
    • (1983) J Immunol Methods , vol.65 , pp. 55-63
    • Mosmann, T.1
  • 28
    • 36549003678 scopus 로고    scopus 로고
    • Downregulation of the monocarboxylate transporter 1 is involved in butyrate deficiency during intestinal inflammation
    • Thibault R, De Coppet P, Daly K, Bourreille A, Cuff M, et al.: Downregulation of the monocarboxylate transporter 1 is involved in butyrate deficiency during intestinal inflammation. Gastroenterology 133, 1916-1927, 2007.
    • (2007) Gastroenterology , vol.133 , pp. 1916-1927
    • Thibault, R.1    De Coppet, P.2    Daly, K.3    Bourreille, A.4    Cuff, M.5
  • 29
    • 0028821119 scopus 로고
    • Dietary fiber increases oxidative metabolism in colonocytes but not in distal small intestinal enterocytes isolated from rats
    • Marsman KE and McBurney MI: Dietary fiber increases oxidative metabolism in colonocytes but not in distal small intestinal enterocytes isolated from rats. J Nutr 125, 273-282, 1995.
    • (1995) J Nutr , vol.125 , pp. 273-282
    • Marsman, K.E.1    McBurney, M.I.2
  • 30
    • 33746506695 scopus 로고    scopus 로고
    • Acute effect of tea, wine, beer, and polyphenols on ecto-alkaline phosphatase activity in human vascular smooth muscle cells
    • DOI 10.1021/jf060505u
    • Negrão MR, Keating E, Faria A, Azevedo I, and Martins MJ: Acute effect of tea, wine, beer, and polyphenols on ecto-alkaline phosphatase activity in human vascular smooth muscle cells. J Agric Food Chem 54, 4982-4988, 2006. (Pubitemid 44140892)
    • (2006) Journal of Agricultural and Food Chemistry , vol.54 , Issue.14 , pp. 4982-4988
    • Negrao, M.R.1    Keating, E.2    Faria, A.3    Azevedo, I.4    Martins, M.J.5
  • 31
    • 0000416021 scopus 로고
    • Lactate dehydrogenase
    • Bergmeyer HU (ed.). New York, Academic Press
    • Bergmeyer HU and Bernt E: Lactate dehydrogenase. In:Methods in Enzymatic Analysis , Bergmeyer HU (ed.). New York, Academic Press, 1974, pp. 574-579.
    • (1974) Methods in Enzymatic Analysis , pp. 574-579
    • Bergmeyer, H.U.1    Bernt, E.2
  • 32
    • 0017184389 scopus 로고
    • A rapid method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford MM: A rapid method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72, 248-254, 1976.
    • (1976) Anal Biochem , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 35
    • 10644230086 scopus 로고    scopus 로고
    • The importance of butyrate transport to the regulation of gene expression in the colonic epithelium
    • DOI 10.1042/BST0321100
    • Cuff MA and Shirazi-Beechey SP: The importance of butyrate transport to the regulation of gene expression in the colonic epithelium. Biochem Soc Trans 32, 1100-1102, 2004. (Pubitemid 39655558)
    • (2004) Biochemical Society Transactions , vol.32 , Issue.6 , pp. 1100-1102
    • Cuff, M.A.1    Shirazi-Beechey, S.P.2
  • 36
    • 0036522023 scopus 로고    scopus 로고
    • Substrate-induced regulation of the human colonic monocarboxylate transporter, MCT1
    • DOI 10.1113/jphysiol.2001.014241
    • Cuff MA, Lambert DW, and Shirazi-Beechey SP: Substrate-induced regulation of the human colonic monocarboxylate transporter, MCT1. J Physiol 539, 361-371, 2002. (Pubitemid 35175393)
    • (2002) Journal of Physiology , vol.539 , Issue.2 , pp. 361-371
    • Cuff, M.A.1    Lambert, D.W.2    Shirazi-Beechey, S.P.3
  • 37
    • 0037008676 scopus 로고    scopus 로고
    • Luminal leptin enhances CD147/MCT-1-mediated uptake of butyrate in the human intestinal cell line Caco2-BBE
    • DOI 10.1074/jbc.M203281200
    • Buyse M, Sitaraman SV, Liu X, Bado A, and Merlin D: Luminal leptin enhances CD147/MCT-1-mediated uptake of butyrate in the human intestinal cell line Caco2-BBE. J Biol Chem 277, 28182-28190, 2002. (Pubitemid 34966772)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.31 , pp. 28182-28190
    • Buyse, M.1    Sitaraman, S.V.2    Liu, X.3    Bado, A.4    Merlin, D.5
  • 40
    • 0033826684 scopus 로고    scopus 로고
    • The health benefits of wine
    • German JB and Walzem RL: The health benefits of wine. Annu Rev Nutr 20, 561-593, 2000.
    • (2000) Annu Rev Nutr , vol.20 , pp. 561-593
    • German, J.B.1    Walzem, R.L.2
  • 41
    • 0033637140 scopus 로고    scopus 로고
    • The effects of plant flavonoids on mammalian cells: Implication for inflammation, heart disease, and cancer
    • Middleton Jr E, Kandaswami C, and Theoharides TC: The effects of plant flavonoids on mammalian cells: implication for inflammation, heart disease, and cancer. Pharmacol Rev 52, 673-751, 2000.
    • (2000) Pharmacol Rev , vol.52 , pp. 673-751
    • Middleton Jr., E.1    Kandaswami, C.2    Theoharides, T.C.3
  • 43
    • 34548379459 scopus 로고    scopus 로고
    • Modulation of folate uptake in cultured human colon adenocarcinoma Caco-2 cells by dietary compounds
    • DOI 10.1007/s00394-007-0670-y
    • Lemos C, Peters GJ, Jansen G, Martel F, and Calhau C: Modulation of folate uptake in cultured human colon adenocarcinoma Caco-2 cells by dietary compounds. Eur J Nutr 46, 329-336, 2007. (Pubitemid 47353607)
    • (2007) European Journal of Nutrition , vol.46 , Issue.6 , pp. 329-336
    • Lemos, C.1    Peters, G.J.2    Jansen, G.3    Martel, F.4    Calhau, C.5
  • 44
    • 48749085911 scopus 로고    scopus 로고
    • Modulation of glucose uptake in a human trophoblast cell line (BeWo) by dietary bioactive compounds and drugs of abuse
    • Araújo JR Gonçalves P, and Martel F: Modulation of glucose uptake in a human trophoblast cell line (BeWo) by dietary bioactive compounds and drugs of abuse. J Biochem 144, 177-186, 2008.
    • (2008) J Biochem , vol.144 , pp. 177-186
    • Araújo, J.R.1    Gonçalves, P.2    Martel, F.3
  • 45
    • 37549048592 scopus 로고    scopus 로고
    • Acute and chronic effects of some dietary bioactive compounds on folic acid uptake and on the expression of folic acid transporters by the human trophoblast cell line BeWo
    • Keating E, Lemos C, Gonçalves P, Azevedo I, and Martel F: Acute and chronic effects of some dietary bioactive compounds on folic acid uptake and on the expression of folic acid transporters by the human trophoblast cell line BeWo. J Nutr Biochem 19, 91-100, 2008.
    • (2008) J Nutr Biochem , vol.19 , pp. 91-100
    • Keating, E.1    Lemos, C.2    Gonçalves, P.3    Azevedo, I.4    Martel, F.5
  • 46
    • 0042423355 scopus 로고    scopus 로고
    • Epigallocatechin-3-gallate-induced stress signals in HT-29 human colon adenocarcinoma cells
    • DOI 10.1093/carcin/bgg091
    • Chen C, Shen G, Hebbar V, Hu R, Owuor ED, and Kong AN: Epigallocatechin-3-gallate-induced stress signals in HT-29 human colon adenocarcinoma cells. Carcinogenesis 24, 1369-1378, 2003. (Pubitemid 37045317)
    • (2003) Carcinogenesis , vol.24 , Issue.8 , pp. 1369-1378
    • Chen, C.1    Shen, G.2    Hebbar, V.3    Hu, R.4    Owuor, E.D.5    Kong, A.-N.T.6
  • 48
    • 0026543798 scopus 로고
    • Growth inhibitory effect of quercetin and presence of type-II estrogen-binding sites in human colon-cancer cell lines and primary colorectal tumors
    • Ranelletti FO, Ricci R, Larocca LM, Maggiano N, Capelli A, et al.: Growth inhibitory effect of quercetin and presence of type-II estrogen-binding sites in human colon-cancer cell lines and primary colorectal tumors. Int J Cancer 50, 486-492, 1992.
    • (1992) Int J Cancer , vol.50 , pp. 486-492
    • Ranelletti, F.O.1    Ricci, R.2    Larocca, L.M.3    Maggiano, N.4    Capelli, A.5
  • 49
    • 1842555356 scopus 로고    scopus 로고
    • Modulatory properties of various natural chemopreventive agents on the activation of NF-κB signaling pathway
    • DOI 10.1023/B:PHAM.0000022413.43212.cf
    • Jeong W-S, Kim I-W, Hu R, and Kong A-NT: Modulatory properties of various natural chemopreventive agents on the activation of NF-κB signaling pathway. Pharm Res 21, 661-670, 2004. (Pubitemid 38457289)
    • (2004) Pharmaceutical Research , vol.21 , Issue.4 , pp. 661-670
    • Jeong, W.-S.1    Kim, I.-W.2    Hu, R.3    Kong, A.-N.T.4
  • 50
    • 3042816689 scopus 로고    scopus 로고
    • Protein expression profiling identifies molecular targets of quercetin as a major dietary flavonoid in human colon cancer cells
    • DOI 10.1002/pmic.200300726
    • Wenzel U, Herzog A, Kuntz S, and Daniel H: Protein expression profiling identifies molecular targets of quercetin as a major dietary flavonoid in human colon cancer cells. Proteomics 4, 2160-2174, 2004. (Pubitemid 38880380)
    • (2004) Proteomics , vol.4 , Issue.7 , pp. 2160-2174
    • Wenzel, U.1    Herzog, A.2    Kuntz, S.3    Daniel, H.4
  • 51
    • 0347626109 scopus 로고    scopus 로고
    • Cancer Prevention by Tea Polyphenols Is Linked to Their Direct Inhibition of Antiapoptotic Bcl-2-Family Proteins
    • Leone M, Zhai D, Sareth S, Kitada S, Reed JC, Pellecchia M: Cancer prevention by tea polyphenols is linked to their direct inhibition of antiapoptotic Bcl-2-family proteins. Cancer Res 63, 8118-8121, 2003. (Pubitemid 37549456)
    • (2003) Cancer Research , vol.63 , Issue.23 , pp. 8118-8121
    • Leone, M.1    Zhai, D.2    Sareth, S.3    Kitada, S.4    Reed, J.C.5    Pellecchia, M.6
  • 53
    • 0033226831 scopus 로고    scopus 로고
    • Inhibition of azoxymethane-induced aberrant crypt foci in rats by natural compounds, caffeine, quercetin and morin
    • Tanaka T, Kawabata K, Honjo S, Kohno H, Murakami M, et al.: Inhibition of azoxymethane-induced aberrant crypt foci in rats by natural compounds, caffeine, quercetin and morin. Oncol Rep 6, 1333-1340, 1999.
    • (1999) Oncol Rep , vol.6 , pp. 1333-1340
    • Tanaka, T.1    Kawabata, K.2    Honjo, S.3    Kohno, H.4    Murakami, M.5
  • 54
    • 0033862118 scopus 로고    scopus 로고
    • Chemoprevention studies of the flavonoids quercetin and rutin in normal and azoxymethane-treated mouse colon
    • Yang K, Lamprecht SA, Liu Y, Shinozaki H, Fan K, et al.: Chemoprevention studies of the flavonoids quercetin and rutin in normal and azoxymethane-treated mouse colon. Carcinogenesis 21, 1655-1660, 2000.
    • (2000) Carcinogenesis , vol.21 , pp. 1655-1660
    • Yang, K.1    Lamprecht, S.A.2    Liu, Y.3    Shinozaki, H.4    Fan, K.5
  • 55
    • 0027485394 scopus 로고
    • The effect of dietary quercetin and rutin on AOM-induced acute colonic epithelial abnormalities in mice fed a high-fat diet
    • Deschner EE, Ruperto JF, Wong GY, and Newmark HL: The effect of dietary quercetin and rutin on AOM-induced acute colonic epithelial abnormalities in mice fed a high-fat diet. Nutr Cancer 20, 199-204, 1993. (Pubitemid 23350020)
    • (1993) Nutrition and Cancer , vol.20 , Issue.3 , pp. 199-204
    • Deschner, E.E.1    Ruperto, J.F.2    Wong, G.Y.3    Newmark, H.L.4
  • 58
    • 3042648789 scopus 로고    scopus 로고
    • Individual and interactive effects of apigenin analogs on G2/M cell-cycle arrest in human colon carcinoma cell lines
    • Wang W, Van Alstyne PC, Irons KA, Chen S, Stewart JW, and Birt DF: Individual and interactive effects of apigenin analogs on G2/M cell-cycle arrest in human colon carcinoma cell lines. Nutr Cancer 48, 106-114, 2004. (Pubitemid 38823552)
    • (2004) Nutrition and Cancer , vol.48 , Issue.1 , pp. 106-114
    • Wang, W.1    VanAlstyne, P.C.2    Irons, K.A.3    Chen, S.4    Stewart, J.W.5    Birt, D.F.6
  • 59
    • 33745005523 scopus 로고    scopus 로고
    • Preventive effects of chrysin on the development of azoxymethane-induced colonic aberrant crypt foci in rats
    • Miyamoto S, Kohno H, Suzuki R, Sugie S, Murakami A, et al.: Preventive effects of chrysin on the development of azoxymethane-induced colonic aberrant crypt foci in rats. Oncol Rep 15, 1169-1173, 2006.
    • (2006) Oncol Rep , vol.15 , pp. 1169-1173
    • Miyamoto, S.1    Kohno, H.2    Suzuki, R.3    Sugie, S.4    Murakami, A.5
  • 60
    • 0141863169 scopus 로고    scopus 로고
    • Biphasic modulation of cell proliferation by quercetin at concentrations physiologically relevant in humans
    • DOI 10.1016/S0304-3835(03)00412-9
    • Van Der Woude H, Gliszczyńska-Swigło A, Struijs K, Smeets A, Alink GM, and Rietjens IM: Biphasic modulation of cell proliferation by quercetin at concentrations physiologically relevant in humans. Cancer Lett 200, 41-47, 2003. (Pubitemid 37222357)
    • (2003) Cancer Letters , vol.200 , Issue.1 , pp. 41-47
    • Van Der Woude, H.1    Gliszczynska-Swigl2    o, A.3    Struijs, K.4    Smeets, A.5    Alink, G.M.6    Rietjens, I.M.C.M.7
  • 61
    • 0035126973 scopus 로고    scopus 로고
    • Resistance to butyrate-induced cell differentiation and apoptosis during spontaneous Caco-2 cell differentiation
    • Mariadason JM, Velcich A, Wilson AJ, Augenlicht LH, and Gibson PR: Resistance to butyrate-induced cell differentiation and apoptosis during spontaneous Caco-2 cell differentiation. Gastroenterology 120, 889-899, 2001. (Pubitemid 32193186)
    • (2001) Gastroenterology , vol.120 , Issue.4 , pp. 889-899
    • Mariadason, J.M.1    Velcich, A.2    Wilson, A.J.3    Augenlicht, L.H.4    Gibson, P.R.5
  • 62
    • 4444234434 scopus 로고    scopus 로고
    • Effect of short-chain fatty acids on the proliferation and differentiation of the human colonic adenocarcinoma cell line Caco-2
    • DOI 10.1111/j.1443-9573.2004.00167.x
    • Fu H, Shi YQ, and Mo SJ: Effect of short-chain fatty acids on the proliferation and differentiation of the human colonic adenocarcinoma cell line Caco-2. Chin J Dig Dis 5, 115-117, 2004. (Pubitemid 39199626)
    • (2004) Chinese Journal of Digestive Diseases , vol.5 , Issue.3 , pp. 115-117
    • Fu, H.1    Shi, Y.Q.2    Mo, S.J.3
  • 63
    • 0033954736 scopus 로고    scopus 로고
    • Coordinate induction by antioxidants of UDP-glucuronosyltransferase UGT1A6 and the apical conjugate export pump MRP2 (multidrug resistance protein 2) in Caco-2 cells
    • DOI 10.1016/S0006-2952(99)00366-4, PII S0006295299003664
    • Bock KW, Eckle T, Ouzzine M, and Fournel-Gigleux S: Coordinate induction by antioxidants of UDP-glucuronosyltransferase UGT1A6 and the apical conjugate export pump MRP2 (multidrug resistance protein 2) in Caco-2 cells. Biochem Pharmacol 59, 467-470, 2000. (Pubitemid 30045584)
    • (2000) Biochemical Pharmacology , vol.59 , Issue.5 , pp. 467-470
    • Bock, K.W.1    Eckle, T.2    Ouzzine, M.3    Fournel-Gigleux, S.4
  • 65
    • 20044371666 scopus 로고    scopus 로고
    • The Caco-2 cell line as a model of the intestinal barrier: Influence of cell and culture-related factors on Caco-2 cell functional characteristics
    • DOI 10.1007/s10565-005-0085-6
    • Sambuy Y, De Angelis I, Ranaldi G, Scarino ML, Stammati A, and Zucco F: The Caco-2 cell line as a model of the intestinal barrier: influence of cell and culture-related factors on Caco-2 cell functional characteristics. Cell Biol Toxicol 21, 1-26, 2005. (Pubitemid 40767684)
    • (2005) Cell Biology and Toxicology , vol.21 , Issue.1 , pp. 1-26
    • Sambuy, Y.1    De, A.I.2    Ranaldi, G.3    Scarino, M.L.4    Stammati, A.5    Zucco, F.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.