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Volumn 36, Issue 1, 2011, Pages 58-63

Atorvastatin attenuates hypoxic pulmonary hypertension in rats by inhibiting RhoA/Rho kinase pathway

Author keywords

Atorvastatin; Hypoxic pulmonary hypertension; RhoA Rho kinase

Indexed keywords

ATORVASTATIN; HEPTANOIC ACID DERIVATIVE; HYPOCHOLESTEROLEMIC AGENT; PYRROLE DERIVATIVE; RHO KINASE; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN;

EID: 79951829287     PISSN: 16727347     EISSN: None     Source Type: Journal    
DOI: 10.3969/j.issn.1672-7347.2011.01.009     Document Type: Article
Times cited : (5)

References (16)
  • 1
    • 30144440291 scopus 로고    scopus 로고
    • Pulmonary hypertension: Cellular and molecular mechanisms [J]
    • Cool C D , Groshong S D , Oakey J , et al. Pulmonary hypertension : cellular and molecular mechanisms [J]. Chest, 2005 , 128(6 Suppl) : 565S-571S.
    • (2005) Chest , vol.128 , Issue.6 SUPPL.
    • Cool, C.D.1    Groshong, S.D.2    Oakey, J.3
  • 2
    • 57049083665 scopus 로고    scopus 로고
    • Analysis of pulmonary vasodilator responses to the Rho-kinase inhibitor fasudil in the anesthetized rat [J]
    • Badejo A M Jr, Dhaliwal J S, Casey D B , et al. Analysis of pulmonary vasodilator responses to the Rho-kinase inhibitor fasudil in the anesthetized rat [J] . Am J Physiol Lung Cell Mol Physiol, 2008 , 295(5) : L828-L836.
    • (2008) Am J Physiol Lung Cell Mol Physiol , vol.295 , Issue.5
    • Badejo Jr., A.M.1    Dhaliwal, J.S.2    Casey, D.B.3
  • 3
    • 33644694919 scopus 로고    scopus 로고
    • Statins, and nitric oxide[J]
    • Kikitake Y, Liao J K. Rho GTPases , statins , and nitric oxide[J]. Cire Res, 2005, 97 (12) : 1 232-1 235.
    • (2005) Cire Res , vol.97 , Issue.12 , pp. 1232-1235
    • Kikitake, Y.1    Liao, J.K.2    Rho, G.3
  • 5
    • 0024837448 scopus 로고
    • A model of rat pulmonary hypertension established by normobaric hypoxia [J]
    • XUE Quanfu, HU Changgui. A model of rat pulmonary hypertension established by normobaric hypoxia [J]. Chinese Journal of Tuberculosis and Respiratory Diseases, 1989, 12 (6): 350-352.
    • (1989) Chinese Journal of Tuberculosis and Respiratory Diseases , vol.12 , Issue.6 , pp. 350-352
    • Xue, Q.1    Hu, C.2
  • 6
    • 33748750883 scopus 로고    scopus 로고
    • The HMG-CoA reductase inhibitor, pravastatin, prevents the development of monocrotaline-induced pulmonary hypertension in the rat through reduction of endothelial cell apoptosis and overexpression of eNOS
    • DOI 10.1007/s00210-006-0082-1
    • Guerard P, Rakotoniaina Z, Goirand F, et al. The HMG-CoA reductase inhibitor, pravastatin, prevents the development of monocrotaline - induced pulmonary hypertension in the rat through reduction of endothelial cell apoptosis and overexpression of eNOS [J]. Naunyn Schmiedebergs Arch Pharmacol, 2006, 373(6) : 401-414. (Pubitemid 44401411)
    • (2006) Naunyn-Schmiedeberg's Archives of Pharmacology , vol.373 , Issue.6 , pp. 401-414
    • Guerard, P.1    Rakotoniaina, Z.2    Goirand, F.3    Rochette, L.4    Dumas, M.5    Lirussi, F.6    Bardou, M.7
  • 7
    • 22744457972 scopus 로고    scopus 로고
    • Vascular remodeling versus vasoconstriction in chronic hypoxic pulmonary hypertension: A time for reappraisal? [J]
    • Stenmark K R , McMurtry I F. Vascular remodeling versus vasoconstriction in chronic hypoxic pulmonary hypertension : A time for reappraisal? [J] . Circ Res, 2005, 97(2) : 95-98.
    • (2005) Circ Res , vol.97 , Issue.2 , pp. 95-98
    • Stenmark, K.R.1    McMurtry, I.F.2
  • 8
    • 34247387518 scopus 로고    scopus 로고
    • Dysregulated bone morphogenetic protein signaling in monocrotaline- induced pulmonary arterial. Hypertension arterioscler [J]
    • Morty R E , Nejman B , Kwapiszewska G , et al. Dysregulated bone morphogenetic protein signaling in monocrotaline-induced pulmonary arterial. Hypertension arterioscler [J]. Arterioscler Thromb Vasc Biol, 2007 , 27 (5) : 1072-1078.
    • (2007) Arterioscler Thromb Vasc Biol , vol.27 , Issue.5 , pp. 1072-1078
    • Morty, R.E.1    Nejman, B.2    Kwapiszewska, G.3
  • 11
    • 33846348016 scopus 로고    scopus 로고
    • Pleiotropic effects of statins and related pharmacological experimental approaches
    • DOI 10.1358/mf.2006.28.9.1003573
    • Alegret M , Silvestre J S. Pleiotropic effects of statins and related pharmacological experimental approaches [J]. Methods Find Exp Clin Pharmacol, 2006, 28(9) : 627-656. (Pubitemid 46133012)
    • (2006) Methods and Findings in Experimental and Clinical Pharmacology , vol.28 , Issue.9 , pp. 627-656
    • Silvestre, J.S.1    Alegret, M.2
  • 12
    • 20144379879 scopus 로고    scopus 로고
    • Statins reduce interleukin-6 induced C-reactive protein in human hepatocytes: New evidence for direct antiinflammatory effects of statins [J]
    • Amaud C, Burger F , Stefens S, et al. Statins reduce interleukin-6 induced C-reactive protein in human hepatocytes : new evidence for direct antiinflammatory effects of statins [J]. Arterioscler Thromb Vase Bio] , 2005, 25 (6) : 1231-1236.
    • (2005) Arterioscler Thromb Vase Bio , vol.25 , Issue.6 , pp. 1231-1236
    • Amaud, C.1    Burger, F.2    Stefens, S.3
  • 13
    • 25444463807 scopus 로고    scopus 로고
    • Atorvastatin reduces lipopolysaccharide - Induced expression of cyclooxygenase-2 in human pulmonary epithelial cells[J]
    • Wu S , Duan S , Zhao S , el al. Atorvastatin reduces lipopolysaccharide - induced expression of cyclooxygenase-2 in human pulmonary epithelial cells[J]. Respir Res, 2005, 6 : 27.
    • (2005) Respir Res , vol.6 , pp. 27
    • Wu, S.1    Duan, S.2    Zhao, S.3
  • 15
    • 62749168355 scopus 로고    scopus 로고
    • Effect of atorvastatin on lipopolysaccharide - Induced expression of C-reactive protein in human pulmonary epithelial cells [J]
    • WU Shangjie , XING Xiqian , GAN Ye , et al. Effect of atorvastatin on lipopolysaccharide - induced expression of C-reactive protein in human pulmonary epithelial cells [J]. Journal of Central South University. Medical Science, 2009, 34 (2) : 104-108.
    • (2009) Journal of Central South University. Medical Science , vol.34 , Issue.2 , pp. 104-108
    • Wu, S.1    Xing, X.2    Gan, Y.3
  • 16
    • 78149256328 scopus 로고    scopus 로고
    • Atorvastatin attenuates inflammatory infiltration and vascular remodeling in lung of hypercholesterolemia rabbits [J]
    • Duan S , Zhang Y , Wu S J , et al. Atorvastatin attenuates inflammatory infiltration and vascular remodeling in lung of hypercholesterolemia rabbits [J]. Exp Lung Res, 2010, 36 (10) : 573-592.
    • (2010) Exp Lung Res , vol.36 , Issue.10 , pp. 573-592
    • Duan, S.1    Zhang, Y.2    Wu, S.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.