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Volumn 53, Issue 2, 2011, Pages 245-258

Interdigital cell death function and regulation: New insights on an old programmed cell death model

Author keywords

Apoptosis; Limb; Morphogenesis; Programmed cell death

Indexed keywords

ADAMTS1 PROTEIN; BETA CATENIN; BONE MORPHOGENETIC PROTEIN; DICKKOPF 1 PROTEIN; FIBRILLIN 2; FIBROBLAST GROWTH FACTOR 8; JAGGED1; LAMININ; NOTCH1 RECEPTOR; NOTCH2 RECEPTOR; RAC1 PROTEIN; RETINOIC ACID; TRANSCRIPTION FACTOR MSX1; TRANSCRIPTION FACTOR MSX2; VERSICAN; WNT PROTEIN;

EID: 79951828231     PISSN: 00121592     EISSN: 1440169X     Source Type: Journal    
DOI: 10.1111/j.1440-169X.2010.01246.x     Document Type: Review
Times cited : (53)

References (118)
  • 1
    • 0035204194 scopus 로고    scopus 로고
    • BMPR-IA signaling is required for the formation of the apical ectodermal ridge and dorsal-ventral patterning of the limb
    • Ahn, K., Mishina, Y., Hanks, M. C., Behringer, R. R. & Crenshaw, E. B. 3rd 2001. BMPR-IA signaling is required for the formation of the apical ectodermal ridge and dorsal-ventral patterning of the limb. Development 128, 4449-4461.
    • (2001) Development , vol.128 , pp. 4449-4461
    • Ahn, K.1    Mishina, Y.2    Hanks, M.C.3    Behringer, R.R.4    Crenshaw 3rd, E.B.5
  • 3
    • 0014291550 scopus 로고
    • Cytological and cytochemical studies on cell death and digestion in the foetal rat foot: the role of macrophages and hydrolytic enzymes
    • Ballard, K. J. & Holt, S. J. 1968. Cytological and cytochemical studies on cell death and digestion in the foetal rat foot: the role of macrophages and hydrolytic enzymes. J. Cell Sci. 3, 245-262.
    • (1968) J. Cell Sci. , vol.3 , pp. 245-262
    • Ballard, K.J.1    Holt, S.J.2
  • 4
    • 33845971522 scopus 로고    scopus 로고
    • Genetic analysis of the roles of BMP2, BMP4, and BMP7 in limb patterning and skeletogenesis
    • Bandyopadhyay, A., Tsuji, K., Cox, K., Harfe, B. D., Rosen, V. & Tabin, C. J. 2006. Genetic analysis of the roles of BMP2, BMP4, and BMP7 in limb patterning and skeletogenesis. PLoS Genet. 2, e216.
    • (2006) PLoS Genet. , vol.2
    • Bandyopadhyay, A.1    Tsuji, K.2    Cox, K.3    Harfe, B.D.4    Rosen, V.5    Tabin, C.J.6
  • 5
    • 0035116463 scopus 로고    scopus 로고
    • Expression pattern of the drm/gremlin gene during chicken embryonic development
    • Bardot, B., Lecoin, L., Huillard, E., Calothy, G. & Marx, M. 2001. Expression pattern of the drm/gremlin gene during chicken embryonic development. Mech. Dev. 101, 263-265.
    • (2001) Mech. Dev. , vol.101 , pp. 263-265
    • Bardot, B.1    Lecoin, L.2    Huillard, E.3    Calothy, G.4    Marx, M.5
  • 6
    • 22444446048 scopus 로고    scopus 로고
    • Gli3 and Plzf cooperate in proximal limb patterning at early stages of limb development
    • Barna, M., Pandolfi, P. P. & Niswander, L. 2005. Gli3 and Plzf cooperate in proximal limb patterning at early stages of limb development. Nature 436, 277-281.
    • (2005) Nature , vol.436 , pp. 277-281
    • Barna, M.1    Pandolfi, P.P.2    Niswander, L.3
  • 7
    • 0032577276 scopus 로고    scopus 로고
    • Noggin, cartilage morphogenesis, and joint formation in the mammalian skeleton
    • Brunet, L. J., Mcmahon, J. A., Mcmahon, A. P. & Harland, R. M. 1998. Noggin, cartilage morphogenesis, and joint formation in the mammalian skeleton. Science 280, 1455-1457.
    • (1998) Science , vol.280 , pp. 1455-1457
    • Brunet, L.J.1    Mcmahon, J.A.2    Mcmahon, A.P.3    Harland, R.M.4
  • 8
    • 0032007417 scopus 로고    scopus 로고
    • Antagonistic effects of FGF4 on BMP induction of apoptosis and chondrogenesis in the chick limb bud
    • Buckland, R. A., Collinson, J. M., Graham, E., Davidson, D. R. & Hill, R. E. 1998. Antagonistic effects of FGF4 on BMP induction of apoptosis and chondrogenesis in the chick limb bud. Mech. Dev. 71, 143-150.
    • (1998) Mech. Dev. , vol.71 , pp. 143-150
    • Buckland, R.A.1    Collinson, J.M.2    Graham, E.3    Davidson, D.R.4    Hill, R.E.5
  • 9
    • 0031046482 scopus 로고    scopus 로고
    • Retinoic acid receptor alpha function in vertebrate limb skeletogenesis: a modulator of chondrogenesis
    • Cash, D. E., Bock, C. B., Schughart, K., Linney, E. & Underhill, T. M. 1997. Retinoic acid receptor alpha function in vertebrate limb skeletogenesis: a modulator of chondrogenesis. J. Cell Biol. 136, 445-457.
    • (1997) J. Cell Biol. , vol.136 , pp. 445-457
    • Cash, D.E.1    Bock, C.B.2    Schughart, K.3    Linney, E.4    Underhill, T.M.5
  • 10
    • 0033539141 scopus 로고    scopus 로고
    • Interdigital cell death can occur through a necrotic and caspase-independent pathway
    • Chautan, M., Chazal, G., Cecconi, F., Gruss, P. & Golstein, P. 1999. Interdigital cell death can occur through a necrotic and caspase-independent pathway. Curr. Biol. 9, 967-970.
    • (1999) Curr. Biol. , vol.9 , pp. 967-970
    • Chautan, M.1    Chazal, G.2    Cecconi, F.3    Gruss, P.4    Golstein, P.5
  • 11
    • 0032534752 scopus 로고    scopus 로고
    • Shaping limbs by apoptosis
    • Chen, Y. & Zhao, X. 1998. Shaping limbs by apoptosis. J. Exp. Zool. 282, 691-702.
    • (1998) J. Exp. Zool. , vol.282 , pp. 691-702
    • Chen, Y.1    Zhao, X.2
  • 12
    • 0025283961 scopus 로고
    • Developmental cell death: morphological diversity and multiple mechanisms
    • Clarke, P. G. 1990. Developmental cell death: morphological diversity and multiple mechanisms. Anat. Embryol. (Berl.) 181, 195-213.
    • (1990) Anat. Embryol. (Berl.) , vol.181 , pp. 195-213
    • Clarke, P.G.1
  • 13
    • 0142074405 scopus 로고    scopus 로고
    • Spatial and temporal patterns of ERK signaling during mouse embryogenesis
    • Corson, L. B., Yamanaka, Y., Lai, K. M. & Rossant, J. 2003. Spatial and temporal patterns of ERK signaling during mouse embryogenesis. Development 130, 4527-4537.
    • (2003) Development , vol.130 , pp. 4527-4537
    • Corson, L.B.1    Yamanaka, Y.2    Lai, K.M.3    Rossant, J.4
  • 14
    • 1642514680 scopus 로고    scopus 로고
    • Death is the major fate of medial edge epithelial cells and the cause of basal lamina degradation during palatogenesis
    • Cuervo, R. & Covarrubias, L. 2004. Death is the major fate of medial edge epithelial cells and the cause of basal lamina degradation during palatogenesis. Development 131, 15-24.
    • (2004) Development , vol.131 , pp. 15-24
    • Cuervo, R.1    Covarrubias, L.2
  • 15
    • 0036570365 scopus 로고    scopus 로고
    • Programmed cell death is required for palate shelf fusion and is regulated by retinoic acid
    • Cuervo, R., Valencia, C., Chandraratna, R. A. & Covarrubias, L. 2002. Programmed cell death is required for palate shelf fusion and is regulated by retinoic acid. Dev. Biol. 245, 145-156.
    • (2002) Dev. Biol. , vol.245 , pp. 145-156
    • Cuervo, R.1    Valencia, C.2    Chandraratna, R.A.3    Covarrubias, L.4
  • 16
    • 0034698302 scopus 로고    scopus 로고
    • Interdigital regulation of digit identity and homeotic transformation by modulated BMP signaling
    • Dahn, R. D. & Fallon, J. F. 2000. Interdigital regulation of digit identity and homeotic transformation by modulated BMP signaling. Science 289, 438-441.
    • (2000) Science , vol.289 , pp. 438-441
    • Dahn, R.D.1    Fallon, J.F.2
  • 17
    • 0021827570 scopus 로고
    • Retinoic acid-induced expression of tissue transglutaminase in human promyelocytic leukemia (HL-60) cells
    • Davies, P. J., Murtaugh, M. P., Moore, W. T. Jr, Johnson, G. S. & Lucas, D. 1985. Retinoic acid-induced expression of tissue transglutaminase in human promyelocytic leukemia (HL-60) cells. J. Biol. Chem. 260, 5166-5174.
    • (1985) J. Biol. Chem. , vol.260 , pp. 5166-5174
    • Davies, P.J.1    Murtaugh, M.P.2    Moore Jr, W.T.3    Johnson, G.S.4    Lucas, D.5
  • 18
    • 0028009121 scopus 로고
    • Developmental expression of murine retinoid X receptor (RXR) genes
    • Dolle, P., Fraulob, V., Kastner, P. & Chambon, P. 1994. Developmental expression of murine retinoid X receptor (RXR) genes. Mech. Dev. 45, 91-104.
    • (1994) Mech. Dev. , vol.45 , pp. 91-104
    • Dolle, P.1    Fraulob, V.2    Kastner, P.3    Chambon, P.4
  • 19
    • 0024367398 scopus 로고
    • Differential expression of genes encoding alpha, beta and gamma retinoic acid receptors and CRABP in the developing limbs of the mouse
    • Dolle, P., Ruberte, E., Kastner, P., Petkovich, M., Stoner, C. M., Gudas, L. J. & Chambon, P. 1989. Differential expression of genes encoding alpha, beta and gamma retinoic acid receptors and CRABP in the developing limbs of the mouse. Nature 342, 702-705.
    • (1989) Nature , vol.342 , pp. 702-705
    • Dolle, P.1    Ruberte, E.2    Kastner, P.3    Petkovich, M.4    Stoner, C.M.5    Gudas, L.J.6    Chambon, P.7
  • 20
    • 0036226831 scopus 로고    scopus 로고
    • TGF-beta is required for programmed cell death in interdigital webs of the developing mouse limb
    • Dunker, N., Schmitt, K. & Krieglstein, K. 2002. TGF-beta is required for programmed cell death in interdigital webs of the developing mouse limb. Mech. Dev. 113, 111-120.
    • (2002) Mech. Dev. , vol.113 , pp. 111-120
    • Dunker, N.1    Schmitt, K.2    Krieglstein, K.3
  • 21
    • 0033120650 scopus 로고    scopus 로고
    • Essential roles of retinoic acid signaling in interdigital apoptosis and control of BMP-7 expression in mouse autopods
    • Dupe, V., Ghyselinck, N. B., Thomazy, V., Nagy, L., Davies, P. J., Chambon, P. & Mark, M. 1999. Essential roles of retinoic acid signaling in interdigital apoptosis and control of BMP-7 expression in mouse autopods. Dev. Biol. 208, 30-43.
    • (1999) Dev. Biol. , vol.208 , pp. 30-43
    • Dupe, V.1    Ghyselinck, N.B.2    Thomazy, V.3    Nagy, L.4    Davies, P.J.5    Chambon, P.6    Mark, M.7
  • 22
    • 77958452297 scopus 로고    scopus 로고
    • 5 Pyst1/MKP3, a novel dual-specificity phosphatase, and FGF signalling in chick limb development
    • Eblaghie, M., Sanz-Ezquerro, J., Dickinson, R., Munsterberg, A., Keyse, S. & Tickle, C. 2002. 5 Pyst1/MKP3, a novel dual-specificity phosphatase, and FGF signalling in chick limb development. J. Anat. 201, 418.
    • (2002) J. Anat. , vol.201 , pp. 418
    • Eblaghie, M.1    Sanz-Ezquerro, J.2    Dickinson, R.3    Munsterberg, A.4    Keyse, S.5    Tickle, C.6
  • 23
    • 0017623150 scopus 로고
    • Interdigital cell death during limb development of the turtle and lizard with an interpretation of evolutionary significance
    • Fallon, J. F. & Cameron, J. 1977. Interdigital cell death during limb development of the turtle and lizard with an interpretation of evolutionary significance. J. Embryol. Exp. Morphol. 40, 285-289.
    • (1977) J. Embryol. Exp. Morphol. , vol.40 , pp. 285-289
    • Fallon, J.F.1    Cameron, J.2
  • 24
    • 0028113568 scopus 로고
    • Expression of activin subunits, activin receptors and follistatin in postimplantation mouse embryos suggests specific developmental functions for different activins
    • Feijen, A., Goumans, M. J. & Van Den Eijnden-Van Raaij, A. J. 1994. Expression of activin subunits, activin receptors and follistatin in postimplantation mouse embryos suggests specific developmental functions for different activins. Development 120, 3621-3637.
    • (1994) Development , vol.120 , pp. 3621-3637
    • Feijen, A.1    Goumans, M.J.2    Van Den Eijnden-Van Raaij, A.J.3
  • 25
    • 33748335734 scopus 로고    scopus 로고
    • Birth and death of cells in limb development: a mapping study
    • Fernandez-Teran, M. A., Hinchliffe, J. R. & Ros, M. A. 2006. Birth and death of cells in limb development: a mapping study. Dev. Dyn. 235, 2521-2537.
    • (2006) Dev. Dyn. , vol.235 , pp. 2521-2537
    • Fernandez-Teran, M.A.1    Hinchliffe, J.R.2    Ros, M.A.3
  • 26
    • 0032080590 scopus 로고    scopus 로고
    • Ectopic expression of Msx-2 in posterior limb bud mesoderm impairs limb morphogenesis while inducing BMP-4 expression, inhibiting cell proliferation, and promoting apoptosis
    • Ferrari, D., Lichtler, A. C., Pan, Z. Z., Dealy, C. N., Upholt, W. B. & Kosher, R. A. 1998. Ectopic expression of Msx-2 in posterior limb bud mesoderm impairs limb morphogenesis while inducing BMP-4 expression, inhibiting cell proliferation, and promoting apoptosis. Dev. Biol. 197, 12-24.
    • (1998) Dev. Biol. , vol.197 , pp. 12-24
    • Ferrari, D.1    Lichtler, A.C.2    Pan, Z.Z.3    Dealy, C.N.4    Upholt, W.B.5    Kosher, R.A.6
  • 27
    • 0028137737 scopus 로고
    • Bone morphogenetic proteins and a signalling pathway that controls patterning in the developing chick limb
    • Francis, P. H., Richardson, M. K., Brickell, P. M. & Tickle, C. 1994. Bone morphogenetic proteins and a signalling pathway that controls patterning in the developing chick limb. Development 120, 209-218.
    • (1994) Development , vol.120 , pp. 209-218
    • Francis, P.H.1    Richardson, M.K.2    Brickell, P.M.3    Tickle, C.4
  • 28
    • 0030872361 scopus 로고    scopus 로고
    • Metabolic inactivation of retinoic acid by a novel P450 differentially expressed in developing mouse embryos
    • Fujii, H., Sato, T., Kaneko, S., Gotoh, O., Fujii-Kuriyama, Y., Osawa, K., Kato, S. & Hamada, H. 1997. Metabolic inactivation of retinoic acid by a novel P450 differentially expressed in developing mouse embryos. EMBO J. 16, 4163-4173.
    • (1997) EMBO J. , vol.16 , pp. 4163-4173
    • Fujii, H.1    Sato, T.2    Kaneko, S.3    Gotoh, O.4    Fujii-Kuriyama, Y.5    Osawa, K.6    Kato, S.7    Hamada, H.8
  • 29
    • 0032054908 scopus 로고    scopus 로고
    • Morphological diversity of the avian foot is related with the pattern of msx gene expression in the developing autopod
    • Ganan, Y., Macias, D., Basco, R. D., Merino, R. & Hurle, J. M. 1998. Morphological diversity of the avian foot is related with the pattern of msx gene expression in the developing autopod. Dev. Biol. 196, 33-41.
    • (1998) Dev. Biol. , vol.196 , pp. 33-41
    • Ganan, Y.1    Macias, D.2    Basco, R.D.3    Merino, R.4    Hurle, J.M.5
  • 30
    • 0027375474 scopus 로고
    • Internucleosomal DNA fragmentation and programmed cell death (apoptosis) in the interdigital tissue of the embryonic chick leg bud
    • Garcia-Martinez, V., Macias, D., Ganan, Y., Garcia-Lobo, J. M., Francia, M. V., Fernandez-Teran, M. A. & Hurle, J. M. 1993. Internucleosomal DNA fragmentation and programmed cell death (apoptosis) in the interdigital tissue of the embryonic chick leg bud. J. Cell Sci. 106, (Pt) 201-208.
    • (1993) J. Cell Sci. , vol.106 , Issue.PART , pp. 201-208
    • Garcia-Martinez, V.1    Macias, D.2    Ganan, Y.3    Garcia-Lobo, J.M.4    Francia, M.V.5    Fernandez-Teran, M.A.6    Hurle, J.M.7
  • 31
    • 0026648674 scopus 로고
    • Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation
    • Gavrieli, Y., Sherman, Y. & Ben-Sasson, S. A. 1992. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J. Cell Biol. 119, 493-501.
    • (1992) J. Cell Biol. , vol.119 , pp. 493-501
    • Gavrieli, Y.1    Sherman, Y.2    Ben-Sasson, S.A.3
  • 34
    • 0036500653 scopus 로고    scopus 로고
    • The Wnt antagonist Dickkopf-1 is regulated by Bmp signaling and c-Jun and modulates programmed cell death
    • Grotewold, L. & Ruther, U. 2002. The Wnt antagonist Dickkopf-1 is regulated by Bmp signaling and c-Jun and modulates programmed cell death. EMBO J. 21, 966-975.
    • (2002) EMBO J. , vol.21 , pp. 966-975
    • Grotewold, L.1    Ruther, U.2
  • 35
    • 0036382871 scopus 로고    scopus 로고
    • In vivo evidence that BMP signaling is necessary for apoptosis in the mouse limb
    • Guha, U., Gomes, W. A., Kobayashi, T., Pestell, R. G. & Kessler, J. A. 2002. In vivo evidence that BMP signaling is necessary for apoptosis in the mouse limb. Dev. Biol. 249, 108-120.
    • (2002) Dev. Biol. , vol.249 , pp. 108-120
    • Guha, U.1    Gomes, W.A.2    Kobayashi, T.3    Pestell, R.G.4    Kessler, J.A.5
  • 36
    • 0027018236 scopus 로고
    • A series of normal stages in the development of the chick embryo. 1951
    • Hamburger, V. & Hamilton, H. L. 1992. A series of normal stages in the development of the chick embryo. 1951. Dev. Dyn. 195, 231-272.
    • (1992) Dev. Dyn. , vol.195 , pp. 231-272
    • Hamburger, V.1    Hamilton, H.L.2
  • 37
    • 70350136098 scopus 로고    scopus 로고
    • Progressive interdigital cell death: regulation by the antagonistic interaction between fibroblast growth factor 8 and retinoic acid
    • Hernandez-Martinez, R., Castro-Obregon, S. & Covarrubias, L. 2009. Progressive interdigital cell death: regulation by the antagonistic interaction between fibroblast growth factor 8 and retinoic acid. Development 136, 3669-3678.
    • (2009) Development , vol.136 , pp. 3669-3678
    • Hernandez-Martinez, R.1    Castro-Obregon, S.2    Covarrubias, L.3
  • 38
    • 0028306029 scopus 로고
    • Macrophage recruitment during limb development and wound healing in the embryonic and foetal mouse
    • Hopkinson-Woolley, J., Hughes, D., Gordon, S. & Martin, P. 1994. Macrophage recruitment during limb development and wound healing in the embryonic and foetal mouse. J. Cell Sci. 107, (Pt 5) 1159-1167.
    • (1994) J. Cell Sci. , vol.107 , Issue.PART 5 , pp. 1159-1167
    • Hopkinson-Woolley, J.1    Hughes, D.2    Gordon, S.3    Martin, P.4
  • 39
    • 0031193368 scopus 로고    scopus 로고
    • Insertional mutation of the mouse Msx1 homeobox gene by an nlacZ reporter gene
    • Houzelstein, D., Cohen, A., Buckingham, M. E. & Robert, B. 1997. Insertional mutation of the mouse Msx1 homeobox gene by an nlacZ reporter gene. Mech. Dev. 65, 123-133.
    • (1997) Mech. Dev. , vol.65 , pp. 123-133
    • Houzelstein, D.1    Cohen, A.2    Buckingham, M.E.3    Robert, B.4
  • 40
    • 73549092480 scopus 로고    scopus 로고
    • Functional cooperation of the proapoptotic Bcl2 family proteins Bmf and Bim in vivo
    • Hubner, A., Cavanagh-Kyros, J., Rincon, M., Flavell, R. A. & Davis, R. J. 2010. Functional cooperation of the proapoptotic Bcl2 family proteins Bmf and Bim in vivo. Mol. Cell. Biol. 30, 98-105.
    • (2010) Mol. Cell. Biol. , vol.30 , pp. 98-105
    • Hubner, A.1    Cavanagh-Kyros, J.2    Rincon, M.3    Flavell, R.A.4    Davis, R.J.5
  • 41
    • 0027478216 scopus 로고
    • A mouse model of Greig cephalopolysyndactyly syndrome: the extra-toesJ mutation contains an intragenic deletion of the Gli3 gene
    • Hui, C. C. & Joyner, A. L. 1993. A mouse model of Greig cephalopolysyndactyly syndrome: the extra-toesJ mutation contains an intragenic deletion of the Gli3 gene. Nat Genet. 3, 241-246.
    • (1993) Nat Genet , vol.3 , pp. 241-246
    • Hui, C.C.1    Joyner, A.L.2
  • 42
    • 0021004950 scopus 로고
    • Fine structure of the regressing interdigital membranes during the formation of the digits of the chick embryo leg bud
    • Hurle, J. M. & Fernandez-Teran, M. A. 1983. Fine structure of the regressing interdigital membranes during the formation of the digits of the chick embryo leg bud. J. Embryol. Exp. Morphol. 78, 195-209.
    • (1983) J. Embryol. Exp. Morphol. , vol.78 , pp. 195-209
    • Hurle, J.M.1    Fernandez-Teran, M.A.2
  • 43
    • 0029944142 scopus 로고    scopus 로고
    • Role of Ced-3/ICE-family proteases in staurosporine-induced programmed cell death
    • Jacobsen, M. D., Weil, M. & Raff, M. C. 1996. Role of Ced-3/ICE-family proteases in staurosporine-induced programmed cell death. J. Cell Biol. 133, 1041-1051.
    • (1996) J. Cell Biol. , vol.133 , pp. 1041-1051
    • Jacobsen, M.D.1    Weil, M.2    Raff, M.C.3
  • 44
    • 0030947095 scopus 로고    scopus 로고
    • Programmed cell death in animal development
    • Jacobson, M. D., Weil, M. & Raff, M. C. 1997. Programmed cell death in animal development. Cell 88, 347-354.
    • (1997) Cell , vol.88 , pp. 347-354
    • Jacobson, M.D.1    Weil, M.2    Raff, M.C.3
  • 45
    • 0026782359 scopus 로고
    • Induction of tissue transglutaminase and apoptosis by retinoic acid in the limb bud
    • Jiang, H. & Kochhar, D. M. 1992. Induction of tissue transglutaminase and apoptosis by retinoic acid in the limb bud. Teratology 46, 333-340.
    • (1992) Teratology , vol.46 , pp. 333-340
    • Jiang, H.1    Kochhar, D.M.2
  • 46
    • 0028168007 scopus 로고
    • Genetic analysis of RXR alpha developmental function: convergence of RXR and RAR signaling pathways in heart and eye morphogenesis
    • Kastner, P., Grondona, J. M., Mark, M., Gansmuller, A., Lemeur, M., Decimo, D., Vonesch, J. L., Dolle, P. & Chambon, P. 1994. Genetic analysis of RXR alpha developmental function: convergence of RXR and RAR signaling pathways in heart and eye morphogenesis. Cell 78, 987-1003.
    • (1994) Cell , vol.78 , pp. 987-1003
    • Kastner, P.1    Grondona, J.M.2    Mark, M.3    Gansmuller, A.4    Lemeur, M.5    Decimo, D.6    Vonesch, J.L.7    Dolle, P.8    Chambon, P.9
  • 47
    • 0031054372 scopus 로고    scopus 로고
    • Genetic evidence that the retinoid signal is transduced by heterodimeric RXR/RAR functional units during mouse development
    • Kastner, P., Mark, M., Ghyselinck, N., Krezel, W., Dupe, V., Grondona, J. M. & Chambon, P. 1997. Genetic evidence that the retinoid signal is transduced by heterodimeric RXR/RAR functional units during mouse development. Development 124, 313-326.
    • (1997) Development , vol.124 , pp. 313-326
    • Kastner, P.1    Mark, M.2    Ghyselinck, N.3    Krezel, W.4    Dupe, V.5    Grondona, J.M.6    Chambon, P.7
  • 50
    • 0027754637 scopus 로고
    • Evidence that retinoic acid-induced apoptosis in the mouse limb bud core mesenchymal cells is gene-mediated
    • Kochhar, D. M., Jiang, H., Harnish, D. C. & Soprano, D. R. 1993. Evidence that retinoic acid-induced apoptosis in the mouse limb bud core mesenchymal cells is gene-mediated. Prog. Clin. Biol. Res. 383B, 815-825.
    • (1993) Prog. Clin. Biol. Res. , vol.383 B , pp. 815-825
    • Kochhar, D.M.1    Jiang, H.2    Harnish, D.C.3    Soprano, D.R.4
  • 53
    • 0029956641 scopus 로고    scopus 로고
    • Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice
    • Kuida, K., Zheng, T. S., Na, S., Kuan, C., Yang, D., Karasuyama, H., Rakic, P. & Flavell, R. A. 1996. Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice. Nature 384, 368-372.
    • (1996) Nature , vol.384 , pp. 368-372
    • Kuida, K.1    Zheng, T.S.2    Na, S.3    Kuan, C.4    Yang, D.5    Karasuyama, H.6    Rakic, P.7    Flavell, R.A.8
  • 55
    • 23144435172 scopus 로고    scopus 로고
    • Analysis of Msx1; Msx2 double mutants reveals multiple roles for Msx genes in limb development
    • Lallemand, Y., Nicola, M. A., Ramos, C., Bach, A., Cloment, C. S. & Robert, B. 2005. Analysis of Msx1; Msx2 double mutants reveals multiple roles for Msx genes in limb development. Development 132, 3003-3014.
    • (2005) Development , vol.132 , pp. 3003-3014
    • Lallemand, Y.1    Nicola, M.A.2    Ramos, C.3    Bach, A.4    Cloment, C.S.5    Robert, B.6
  • 56
    • 0037902355 scopus 로고    scopus 로고
    • Activation of in situ tissue transglutaminase by intracellular reactive oxygen species
    • Lee, Z. W., Kwon, S. M., Kim, S. W., Yi, S. J., Kim, Y. M. & Ha, K. S. 2003. Activation of in situ tissue transglutaminase by intracellular reactive oxygen species. Biochem. Biophys. Res. Commun. 305, 633-640.
    • (2003) Biochem. Biophys. Res. Commun. , vol.305 , pp. 633-640
    • Lee, Z.W.1    Kwon, S.M.2    Kim, S.W.3    Yi, S.J.4    Kim, Y.M.5    Ha, K.S.6
  • 57
    • 0033673531 scopus 로고    scopus 로고
    • Fgf8 signalling from the AER is essential for normal limb development
    • Lewandoski, M., Sun, X. & Martin, G. R. 2000. Fgf8 signalling from the AER is essential for normal limb development. Nat. Genet. 26, 460-463.
    • (2000) Nat. Genet. , vol.26 , pp. 460-463
    • Lewandoski, M.1    Sun, X.2    Martin, G.R.3
  • 58
    • 33846472047 scopus 로고    scopus 로고
    • Dusp6 (Mkp3) is a negative feedback regulator of FGF-stimulated ERK signaling during mouse development
    • Li, C., Scott, D. A., Hatch, E., Tian, X. & Mansour, S. L. 2007. Dusp6 (Mkp3) is a negative feedback regulator of FGF-stimulated ERK signaling during mouse development. Development 134, 167-176.
    • (2007) Development , vol.134 , pp. 167-176
    • Li, C.1    Scott, D.A.2    Hatch, E.3    Tian, X.4    Mansour, S.L.5
  • 60
    • 31644445191 scopus 로고    scopus 로고
    • Increasing Fgf4 expression in the mouse limb bud causes polysyndactyly and rescues the skeletal defects that result from loss of Fgf8 function
    • Lu, P., Minowada, G. & Martin, G. R. 2006. Increasing Fgf4 expression in the mouse limb bud causes polysyndactyly and rescues the skeletal defects that result from loss of Fgf8 function. Development 133, 33-42.
    • (2006) Development , vol.133 , pp. 33-42
    • Lu, P.1    Minowada, G.2    Martin, G.R.3
  • 61
    • 0028960753 scopus 로고
    • Colocalization of BMP 7 and BMP 2 RNAs suggests that these factors cooperatively mediate tissue interactions during murine development
    • Lyons, K. M., Hogan, B. L. & Robertson, E. J. 1995. Colocalization of BMP 7 and BMP 2 RNAs suggests that these factors cooperatively mediate tissue interactions during murine development. Mech. Dev. 50, 71-83.
    • (1995) Mech. Dev. , vol.50 , pp. 71-83
    • Lyons, K.M.1    Hogan, B.L.2    Robertson, E.J.3
  • 62
    • 60549103019 scopus 로고    scopus 로고
    • In the limb AER Bmp2 and Bmp4 are required for dorsal-ventral patterning and interdigital cell death but not limb outgrowth
    • Maatouk, D. M., Choi, K. S., Bouldin, C. M. & Harfe, B. D. 2009. In the limb AER Bmp2 and Bmp4 are required for dorsal-ventral patterning and interdigital cell death but not limb outgrowth. Dev. Biol. 327, 516-523.
    • (2009) Dev. Biol. , vol.327 , pp. 516-523
    • Maatouk, D.M.1    Choi, K.S.2    Bouldin, C.M.3    Harfe, B.D.4
  • 63
    • 0029999737 scopus 로고    scopus 로고
    • In vivo inhibition of programmed cell death by local administration of FGF-2 and FGF-4 in the interdigital areas of the embryonic chick leg bud
    • Macias, D., Ganan, Y., Ros, M. A. & Hurle, J. M. 1996. In vivo inhibition of programmed cell death by local administration of FGF-2 and FGF-4 in the interdigital areas of the embryonic chick leg bud. Anat. Embryol. (Berl.) 193, 533-541.
    • (1996) Anat. Embryol. (Berl.) , vol.193 , pp. 533-541
    • Macias, D.1    Ganan, Y.2    Ros, M.A.3    Hurle, J.M.4
  • 64
    • 0034886924 scopus 로고    scopus 로고
    • Cloning of a novel retinoic-acid metabolizing cytochrome P450, Cyp26B1, and comparative expression analysis with Cyp26A1 during early murine development
    • Maclean, G., Abu-Abed, S., Dolle, P., Tahayato, A., Chambon, P. & Petkovich, M. 2001. Cloning of a novel retinoic-acid metabolizing cytochrome P450, Cyp26B1, and comparative expression analysis with Cyp26A1 during early murine development. Mech. Dev. 107, 195-201.
    • (2001) Mech. Dev. , vol.107 , pp. 195-201
    • Maclean, G.1    Abu-Abed, S.2    Dolle, P.3    Tahayato, A.4    Chambon, P.5    Petkovich, M.6
  • 65
    • 43749110077 scopus 로고    scopus 로고
    • Genetic evidence that FGFs have an instructive role in limb proximal-distal patterning
    • Mariani, F. V., Ahn, C. P. & Martin, G. R. 2008. Genetic evidence that FGFs have an instructive role in limb proximal-distal patterning. Nature 453, 401-405.
    • (2008) Nature , vol.453 , pp. 401-405
    • Mariani, F.V.1    Ahn, C.P.2    Martin, G.R.3
  • 67
    • 50249103834 scopus 로고    scopus 로고
    • The cell biology of autophagy in metazoans: a developing story
    • Melendez, A. & Neufeld, T. P. 2008. The cell biology of autophagy in metazoans: a developing story. Development 135, 2347-2360.
    • (2008) Development , vol.135 , pp. 2347-2360
    • Melendez, A.1    Neufeld, T.P.2
  • 68
    • 0033402727 scopus 로고    scopus 로고
    • The BMP antagonist Gremlin regulates outgrowth, chondrogenesis and programmed cell death in the developing limb
    • Merino, R., Rodriguez-Leon, J., Macias, D., Ganan, Y., Economides, A. N. & Hurle, J. M. 1999. The BMP antagonist Gremlin regulates outgrowth, chondrogenesis and programmed cell death in the developing limb. Development 126, 5515-5522.
    • (1999) Development , vol.126 , pp. 5515-5522
    • Merino, R.1    Rodriguez-Leon, J.2    Macias, D.3    Ganan, Y.4    Economides, A.N.5    Hurle, J.M.6
  • 69
    • 0032517785 scopus 로고    scopus 로고
    • Roles for laminin in embryogenesis: exencephaly, syndactyly, and placentopathy in mice lacking the laminin alpha5 chain
    • Miner, J. H., Cunningham, J. & Sanes, J. R. 1998. Roles for laminin in embryogenesis: exencephaly, syndactyly, and placentopathy in mice lacking the laminin alpha5 chain. J. Cell Biol. 143, 1713-1723.
    • (1998) J. Cell Biol. , vol.143 , pp. 1713-1723
    • Miner, J.H.1    Cunningham, J.2    Sanes, J.R.3
  • 70
    • 75749122303 scopus 로고    scopus 로고
    • Methods in mammalian autophagy research
    • Mizushima, N., Yoshimori, T. & Levine, B. 2010. Methods in mammalian autophagy research. Cell 140, 313-326.
    • (2010) Cell , vol.140 , pp. 313-326
    • Mizushima, N.1    Yoshimori, T.2    Levine, B.3
  • 71
    • 0034214303 scopus 로고    scopus 로고
    • Tissue-specific expression of retinoic acid receptor isoform transcripts in the mouse embryo
    • Mollard, R., Viville, S., Ward, S. J., Decimo, D., Chambon, P. & Dolle, P. 2000. Tissue-specific expression of retinoic acid receptor isoform transcripts in the mouse embryo. Mech. Dev. 94, 223-232.
    • (2000) Mech. Dev. , vol.94 , pp. 223-232
    • Mollard, R.1    Viville, S.2    Ward, S.J.3    Decimo, D.4    Chambon, P.5    Dolle, P.6
  • 72
    • 79951835961 scopus 로고    scopus 로고
    • Coordinated and sequential activation of neutral and acidic DNases during interdigital cell death in the embryonic limb
    • Montero, J. A., Lorda-Diez, C. I., Certal, A. C., Moreno, N., Rodriguez-Leon, J., Torriglia, A. & Hurle, J. M. 2010. Coordinated and sequential activation of neutral and acidic DNases during interdigital cell death in the embryonic limb. Apoptosis 94, 223-232.
    • (2010) Apoptosis , vol.94 , pp. 223-232
    • Montero, J.A.1    Lorda-Diez, C.I.2    Certal, A.C.3    Moreno, N.4    Rodriguez-Leon, J.5    Torriglia, A.6    Hurle, J.M.7
  • 75
    • 77952236408 scopus 로고    scopus 로고
    • Apaf-1-independent programmed cell death in mouse development
    • Nagasaka, A., Kawane, K., Yoshida, H. & Nagata, S. 2010. Apaf-1-independent programmed cell death in mouse development. Cell Death Differ. 17, 931-941.
    • (2010) Cell Death Differ. , vol.17 , pp. 931-941
    • Nagasaka, A.1    Kawane, K.2    Yoshida, H.3    Nagata, S.4
  • 76
    • 0035798645 scopus 로고    scopus 로고
    • Identification of a caspase-9 substrate and detection of its cleavage in programmed cell death during mouse development
    • Nakanishi, K., Maruyama, M., Shibata, T. & Morishima, N. 2001. Identification of a caspase-9 substrate and detection of its cleavage in programmed cell death during mouse development. J. Biol. Chem. 276, 41237-41244.
    • (2001) J. Biol. Chem. , vol.276 , pp. 41237-41244
    • Nakanishi, K.1    Maruyama, M.2    Shibata, T.3    Morishima, N.4
  • 77
    • 0031080555 scopus 로고    scopus 로고
    • Restricted expression and retinoic acid-induced downregulation of the retinaldehyde dehydrogenase type 2 (RALDH-2) gene during mouse development
    • Niederreither, K., Mccaffery, P., Drager, U. C., Chambon, P. & Dolle, P. 1997. Restricted expression and retinoic acid-induced downregulation of the retinaldehyde dehydrogenase type 2 (RALDH-2) gene during mouse development. Mech. Dev. 62, 67-78.
    • (1997) Mech. Dev. , vol.62 , pp. 67-78
    • Niederreither, K.1    Mccaffery, P.2    Drager, U.C.3    Chambon, P.4    Dolle, P.5
  • 78
    • 0028229760 scopus 로고
    • Bcl-2 protein expression during murine development
    • Novack, D. V. & Korsmeyer, S. J. 1994. Bcl-2 protein expression during murine development. Am. J. Pathol. 145, 61-73.
    • (1994) Am. J. Pathol. , vol.145 , pp. 61-73
    • Novack, D.V.1    Korsmeyer, S.J.2
  • 79
    • 34248589385 scopus 로고    scopus 로고
    • Activities of N-Myc in the developing limb link control of skeletal size with digit separation
    • Ota, S., Zhou, Z. Q., Keene, D. R., Knoepfler, P. & Hurlin, P. J. 2007. Activities of N-Myc in the developing limb link control of skeletal size with digit separation. Development 134, 1583-1592.
    • (2007) Development , vol.134 , pp. 1583-1592
    • Ota, S.1    Zhou, Z.Q.2    Keene, D.R.3    Knoepfler, P.4    Hurlin, P.J.5
  • 81
    • 34347329271 scopus 로고    scopus 로고
    • BMP signals control limb bud interdigital programmed cell death by regulating FGF signaling
    • Pajni-Underwood, S., Wilson, C. P., Elder, C., Mishina, Y. & Lewandoski, M. 2007. BMP signals control limb bud interdigital programmed cell death by regulating FGF signaling. Development 134, 2359-2368.
    • (2007) Development , vol.134 , pp. 2359-2368
    • Pajni-Underwood, S.1    Wilson, C.P.2    Elder, C.3    Mishina, Y.4    Lewandoski, M.5
  • 82
    • 26644446459 scopus 로고    scopus 로고
    • Notch1 and 2 cooperate in limb ectoderm to receive an early Jagged2 signal regulating interdigital apoptosis
    • Pan, Y., Liu, Z., Shen, J. & Kopan, R. 2005. Notch1 and 2 cooperate in limb ectoderm to receive an early Jagged2 signal regulating interdigital apoptosis. Dev. Biol. 286, 472-482.
    • (2005) Dev. Biol. , vol.286 , pp. 472-482
    • Pan, Y.1    Liu, Z.2    Shen, J.3    Kopan, R.4
  • 84
    • 77649179110 scopus 로고    scopus 로고
    • Analysis of Cyp26b1/Rarg compound-null mice reveals two genetically separable effects of retinoic acid on limb outgrowth
    • Pennimpede, T., Cameron, D. A., Maclean, G. A. & Petkovich, M. 2010. Analysis of Cyp26b1/Rarg compound-null mice reveals two genetically separable effects of retinoic acid on limb outgrowth. Dev. Biol. 339, 179-186.
    • (2010) Dev. Biol. , vol.339 , pp. 179-186
    • Pennimpede, T.1    Cameron, D.A.2    Maclean, G.A.3    Petkovich, M.4
  • 86
    • 36448961645 scopus 로고    scopus 로고
    • Engulfment of apoptotic cells: signals for a good meal
    • Ravichandran, K. S. & Lorenz, U. 2007. Engulfment of apoptotic cells: signals for a good meal. Nat. Rev. Immunol. 7, 964-974.
    • (2007) Nat. Rev. Immunol. , vol.7 , pp. 964-974
    • Ravichandran, K.S.1    Lorenz, U.2
  • 87
    • 0033120211 scopus 로고    scopus 로고
    • Paracrine-mediated apoptosis in reproductive tract development
    • Roberts, L. M., Hirokawa, Y., Nachtigal, M. W. & Ingraham, H. A. 1999. Paracrine-mediated apoptosis in reproductive tract development. Dev. Biol. 208, 110-122.
    • (1999) Dev. Biol. , vol.208 , pp. 110-122
    • Roberts, L.M.1    Hirokawa, Y.2    Nachtigal, M.W.3    Ingraham, H.A.4
  • 89
    • 0028228316 scopus 로고
    • Anti-apogens and anti-engulfens: monoclonal antibodies reveal specific antigens on apoptotic and engulfment cells during chicken embryonic development
    • Rotello, R. J., Fernandez, P. A. & Yuan, J. 1994. Anti-apogens and anti-engulfens: monoclonal antibodies reveal specific antigens on apoptotic and engulfment cells during chicken embryonic development. Development 120, 1421-1431.
    • (1994) Development , vol.120 , pp. 1421-1431
    • Rotello, R.J.1    Fernandez, P.A.2    Yuan, J.3
  • 91
    • 0035087189 scopus 로고    scopus 로고
    • Differential tissue growth and patterns of cell death in mouse limb autopod morphogenesis
    • Salas-Vidal, E., Valencia, C. & Covarrubias, L. 2001. Differential tissue growth and patterns of cell death in mouse limb autopod morphogenesis. Dev. Dyn. 220, 295-306.
    • (2001) Dev. Dyn. , vol.220 , pp. 295-306
    • Salas-Vidal, E.1    Valencia, C.2    Covarrubias, L.3
  • 93
    • 34748854519 scopus 로고    scopus 로고
    • Hoxd and Gli3 interactions modulate digit number in the amniote limb
    • Sheth, R., Bastida, M. F. & Ros, M. 2007. Hoxd and Gli3 interactions modulate digit number in the amniote limb. Dev Biol. 310, 430-441.
    • (2007) Dev Biol , vol.310 , pp. 430-441
    • Sheth, R.1    Bastida, M.F.2    Ros, M.3
  • 94
    • 0028175195 scopus 로고
    • RXR alpha mutant mice establish a genetic basis for vitamin A signaling in heart morphogenesis
    • Sucov, H. M., Dyson, E., Gumeringer, C. L., Price, J., Chien, K. R. & Evans, R. M. 1994. RXR alpha mutant mice establish a genetic basis for vitamin A signaling in heart morphogenesis. Genes Dev. 8, 1007-1018.
    • (1994) Genes Dev. , vol.8 , pp. 1007-1018
    • Sucov, H.M.1    Dyson, E.2    Gumeringer, C.L.3    Price, J.4    Chien, K.R.5    Evans, R.M.6
  • 95
    • 0036682468 scopus 로고    scopus 로고
    • Functions of FGF signalling from the apical ectodermal ridge in limb development
    • Sun, X., Mariani, F. V. & Martin, G. R. 2002. Functions of FGF signalling from the apical ectodermal ridge in limb development. Nature 418, 501-508.
    • (2002) Nature , vol.418 , pp. 501-508
    • Sun, X.1    Mariani, F.V.2    Martin, G.R.3
  • 97
    • 41949133128 scopus 로고    scopus 로고
    • Unique SMAD1/5/8 activity at the phalanx-forming region determines digit identity
    • Suzuki, T., Hasso, S. M. & Fallon, J. F. 2008. Unique SMAD1/5/8 activity at the phalanx-forming region determines digit identity. Proc. Natl. Acad. Sci. U S A 105, 4185-4190.
    • (2008) Proc. Natl. Acad. Sci. U S A , vol.105 , pp. 4185-4190
    • Suzuki, T.1    Hasso, S.M.2    Fallon, J.F.3
  • 99
    • 0027427492 scopus 로고
    • Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair
    • Veis, D. J., Sorenson, C. M., Shutter, J. R. & Korsmeyer, S. J. 1993. Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair. Cell 75, 229-240.
    • (1993) Cell , vol.75 , pp. 229-240
    • Veis, D.J.1    Sorenson, C.M.2    Shutter, J.R.3    Korsmeyer, S.J.4
  • 102
    • 33750067962 scopus 로고    scopus 로고
    • Interdigital webbing retention in bat wings illustrates genetic changes underlying amniote limb diversification
    • Weatherbee, S. D., Behringer, R. R., Rasweiler, J. J. T. & Niswander, L. A. 2006. Interdigital webbing retention in bat wings illustrates genetic changes underlying amniote limb diversification. Proc. Natl. Acad. Sci. U S A 103, 15103-15107.
    • (2006) Proc. Natl. Acad. Sci. U S A , vol.103 , pp. 15103-15107
    • Weatherbee, S.D.1    Behringer, R.R.2    Rasweiler, J.J.T.3    Niswander, L.A.4
  • 103
    • 0037108225 scopus 로고    scopus 로고
    • FGFs, their receptors, and human limb malformations: clinical and molecular correlations
    • Wilkie, A. O., Patey, S. J., Kan, S. H., Van Den Ouweland, A. M. & Hamel, B. C. 2002. FGFs, their receptors, and human limb malformations: clinical and molecular correlations. Am. J. Med. Genet. 112, 266-278.
    • (2002) Am. J. Med. Genet. , vol.112 , pp. 266-278
    • Wilkie, A.O.1    Patey, S.J.2    Kan, S.H.3    Van Den Ouweland, A.M.4    Hamel, B.C.5
  • 104
    • 0034521602 scopus 로고    scopus 로고
    • Mesenchymal cells engulf and clear apoptotic footplate cells in macrophageless PU.1 null mouse embryos
    • Wood, W., Turmaine, M., Weber, R., Camp, V., Maki, R. A., Mckercher, S. R. & Martin, P. 2000. Mesenchymal cells engulf and clear apoptotic footplate cells in macrophageless PU.1 null mouse embryos. Development 127, 5245-5252.
    • (2000) Development , vol.127 , pp. 5245-5252
    • Wood, W.1    Turmaine, M.2    Weber, R.3    Camp, V.4    Maki, R.A.5    Mckercher, S.R.6    Martin, P.7
  • 105
    • 1642287727 scopus 로고    scopus 로고
    • Regulation of retinoic acid distribution is required for proximodistal patterning and outgrowth of the developing mouse limb
    • Yashiro, K., Zhao, X., Uehara, M., Yamashita, K., Nishijima, M., Nishino, J., Saijoh, Y., Sakai, Y. & Hamada, H. 2004. Regulation of retinoic acid distribution is required for proximodistal patterning and outgrowth of the developing mouse limb. Dev. Cell 6, 411-422.
    • (2004) Dev. Cell , vol.6 , pp. 411-422
    • Yashiro, K.1    Zhao, X.2    Uehara, M.3    Yamashita, K.4    Nishijima, M.5    Nishino, J.6    Saijoh, Y.7    Sakai, Y.8    Hamada, H.9
  • 106
    • 0033960316 scopus 로고    scopus 로고
    • The type I BMP receptor BMPRIB is required for chondrogenesis in the mouse limb
    • Yi, S. E., Daluiski, A., Pederson, R., Rosen, V. & Lyons, K. M. 2000. The type I BMP receptor BMPRIB is required for chondrogenesis in the mouse limb. Development 127, 621-630.
    • (2000) Development , vol.127 , pp. 621-630
    • Yi, S.E.1    Daluiski, A.2    Pederson, R.3    Rosen, V.4    Lyons, K.M.5
  • 107
    • 40949140612 scopus 로고    scopus 로고
    • A Pro253Arg mutation in fibroblast growth factor receptor 2 (Fgfr2) causes skeleton malformation mimicking human Apert syndrome by affecting both chondrogenesis and osteogenesis
    • Yin, L., Du, X., Li, C., Xu, X., Chen, Z., Su, N., Zhao, L., Qi, H., Li, F., Xue, J., Yang, J., Jin, M., Deng, C. & Chen, L. 2008. A Pro253Arg mutation in fibroblast growth factor receptor 2 (Fgfr2) causes skeleton malformation mimicking human Apert syndrome by affecting both chondrogenesis and osteogenesis. Bone 42, 631-643.
    • (2008) Bone , vol.42 , pp. 631-643
    • Yin, L.1    Du, X.2    Li, C.3    Xu, X.4    Chen, Z.5    Su, N.6    Zhao, L.7    Qi, H.8    Li, F.9    Xue, J.10    Yang, J.11    Jin, M.12    Deng, C.13    Chen, L.14
  • 108
    • 0025947972 scopus 로고
    • Chicken homeobox gene Msx-1: structure, expression in limb buds and effect of retinoic acid
    • Yokouchi, Y., Ohsugi, K., Sasaki, H. & Kuroiwa, A. 1991. Chicken homeobox gene Msx-1: structure, expression in limb buds and effect of retinoic acid. Development 113, 431-444.
    • (1991) Development , vol.113 , pp. 431-444
    • Yokouchi, Y.1    Ohsugi, K.2    Sasaki, H.3    Kuroiwa, A.4
  • 110
    • 41649095548 scopus 로고    scopus 로고
    • FGF signaling regulates mesenchymal differentiation and skeletal patterning along the limb bud proximodistal axis
    • Yu, K. & Ornitz, D. M. 2008. FGF signaling regulates mesenchymal differentiation and skeletal patterning along the limb bud proximodistal axis. Development 135, 483-491.
    • (2008) Development , vol.135 , pp. 483-491
    • Yu, K.1    Ornitz, D.M.2
  • 111
    • 0028040714 scopus 로고
    • Apoptotic cell death in the mouse limb and its suppression in the hammertoe mutant
    • Zakeri, Z., Quaglino, D. & Ahuja, H. S. 1994. Apoptotic cell death in the mouse limb and its suppression in the hammertoe mutant. Dev. Biol. 165, 294-297.
    • (1994) Dev. Biol , vol.165 , pp. 294-297
    • Zakeri, Z.1    Quaglino, D.2    Ahuja, H.S.3
  • 113
    • 77951919230 scopus 로고    scopus 로고
    • Retinoic acid controls expression of tissue remodeling genes Hmgn1 and Fgf18 at the digit-interdigit junction
    • Zhao, X., Brade, T., Cunningham, T. J. & Duester, G. 2010. Retinoic acid controls expression of tissue remodeling genes Hmgn1 and Fgf18 at the digit-interdigit junction. Dev. Dyn. 239, 665-671.
    • (2010) Dev. Dyn. , vol.239 , pp. 665-671
    • Zhao, X.1    Brade, T.2    Cunningham, T.J.3    Duester, G.4
  • 115
    • 0030955344 scopus 로고    scopus 로고
    • Distinct roles of type I bone morphogenetic protein receptors in the formation and differentiation of cartilage
    • Zou, H., Wieser, R., Massague, J. & Niswander, L. 1997. Distinct roles of type I bone morphogenetic protein receptors in the formation and differentiation of cartilage. Genes Dev. 11, 2191-2203.
    • (1997) Genes Dev. , vol.11 , pp. 2191-2203
    • Zou, H.1    Wieser, R.2    Massague, J.3    Niswander, L.4
  • 116
    • 33745048075 scopus 로고    scopus 로고
    • Caspase redundancy and release of mitochondrial apoptotic factors characterize interdigital apoptosis
    • Zuzarte-Luis, V., Berciano, M. T., Lafarga, M. & Hurle, J. M. 2006. Caspase redundancy and release of mitochondrial apoptotic factors characterize interdigital apoptosis. Apoptosis 11, 701-715.
    • (2006) Apoptosis , vol.11 , pp. 701-715
    • Zuzarte-Luis, V.1    Berciano, M.T.2    Lafarga, M.3    Hurle, J.M.4
  • 118
    • 3042778695 scopus 로고    scopus 로고
    • A new role for BMP5 during limb development acting through the synergic activation of Smad and MAPK pathways
    • Zuzarte-Luis, V., Montero, J. A., Rodriguez-Leon, J., Merino, R., Rodriguez-Rey, J. C. & Hurle, J. M. 2004. A new role for BMP5 during limb development acting through the synergic activation of Smad and MAPK pathways. Dev. Biol. 272, 39-52.
    • (2004) Dev. Biol. , vol.272 , pp. 39-52
    • Zuzarte-Luis, V.1    Montero, J.A.2    Rodriguez-Leon, J.3    Merino, R.4    Rodriguez-Rey, J.C.5    Hurle, J.M.6


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