Impact of escaped bone marrow mesenchymal stromal cells on extracardiac organs after intramyocardial implantation in a rat myocardial infarction model

Cell Transplantation

Volumn 19, Issue 12, 2010, Pages 1599-1607

  Wang, Wei ^a,b   Jin, Peifeng ^b,c   Wang, Lei ^b,d   Yang, Zhikai ^a,b   Hu, Shengshou ^b   Gao, Bingren ^a   Zhang, Hao ^b  

^a LANZHOU UNIVERSITY   (China)

^b FUWAI HOSPITAL   (China)

^c WENZHOU MEDICAL UNIVERSITY   (China)

^d WEIFANG MEDICAL UNIVERSITY   (China)

Author keywords

Bone marrow mesenchymal stromal cells; Liver; Lung; Myocardial infarction; Spleen

Indexed keywords

ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; BILIRUBIN GLUCURONIDE; BROXURIDINE; HEMOGLOBIN; IMMUNOGLOBULIN M; INTERLEUKIN 1BETA; MALONALDEHYDE; MYELOPEROXIDASE; PHOSPHATE BUFFERED SALINE; TUMOR NECROSIS FACTOR ALPHA;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALKALINE PHOSPHATASE BLOOD LEVEL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BONE MARROW CELL; CELL MIGRATION; CELL THERAPY; CONTROLLED STUDY; CORONARY ARTERY LIGATION; ECHOCARDIOGRAPHY; ERYTHROCYTE COUNT; FEMALE; FIBROBLAST; FORCED EXPIRATORY VOLUME; FORCED VITAL CAPACITY; HEART FUNCTION; HEART INFARCTION; HEART LEFT VENTRICLE EJECTION FRACTION; HEART LEFT VENTRICLE ENDDIASTOLIC VOLUME; HEART LEFT VENTRICLE ENDSYSTOLIC VOLUME; IMMUNOHISTOCHEMISTRY; LEUKOCYTE COUNT; LIVER CELL; LUNG ALVEOLUS EPITHELIUM; LUNG FUNCTION; MALE; MESENCHYMAL STEM CELL; MESENCHYMAL STEM CELL TRANSPLANTATION; MESENCHYMAL STROMAL CELL; MYOFIBROBLAST; NONHUMAN; PRIORITY JOURNAL; RAT; REAL TIME POLYMERASE CHAIN REACTION; SHAM PROCEDURE; SPLEEN FUNCTION; THERAPY EFFECT; THROMBOCYTE COUNT;

ANIMALS; BONE MARROW CELLS; BONE MARROW TRANSPLANTATION; CELL MOVEMENT; FEMALE; LIVER; LUNG; MALE; MESENCHYMAL STEM CELL TRANSPLANTATION; MESENCHYMAL STEM CELLS; MYOCARDIAL INFARCTION; MYOCARDIUM; RATS; RATS, INBRED LEW; SPLEEN; STROMAL CELLS;

RATTUS;

EID: 79951826923     PISSN: 09636897     EISSN: None     Source Type: Journal    
DOI: 10.3727/096368910X513982     Document Type: Article

References (28)

1. Allen, L. A.; Felker, G. M.; Pocock, S.; McMurray, J. J.; Pfeffer, M. A.; Swedberg, K.; Wang, D.; Yusuf, S.; Michelson, E. L.; Granger, C. B. Liver function abnormalities and outcome in patients with chronic heart failure: Data from the candesartan in heart failure: Assessment of reduction in mortality and morbidity (CHARM) program. Eur. J. Heart Fail. 11(2):170-177; 2009.
2. Alvarez-Dolado, M.; Pardal, R.; Garcia-Verdugo, J. M.; Fike, J. R.; Lee, H. O.; Pfeffer, K.; Lois, C.; Morrison, S. J.; Alvarez-Buylla, A. Fusion of bone-marrow-derived cells with purkinje neurons, cardiomyocytes and hepatocytes. Nature 425(6961):968-973; 2003.
3. Batin, P.; Wickens, M.; McEntegart, D.; Fullwood, L.; Cowley, A. J. The importance of abnormalities of liver function tests in predicting mortality in chronic heart failure. Eur. Heart J. 16(11):1613-1618; 1995.
4. Colletti, E. J.; Airey, J. A.; Liu, W.; Simmons, P. J.; Zanjani, E. D.; Porada, C. D.; Almeida-Porada, G. Generation of tissue-specific cells from MSC does not require fusion or donor-to-host mitochondrial/membrane transfer. Stem Cell Res. 2(2):125-138; 2009.
5. Di Bonzo, L. V.; Ferrero, I.; Cravanzola, C.; Mareschi, K.; Rustichell, D.; Novo, E.; Sanavio, F.; Cannito, S.; Zamara, E.; Bertero, M.; Davit, A.; Francica, S.; Novelli, F.; Colombatto, S.; Fagioli, F.; Parola, M. Human mesenchymal stem cells as a two-edged sword in hepatic regenerative medicine: Engraftment and hepatocyte differentiation versus profibrogenic potential. Gut 57(2):223-231; 2008.
6. Falimirski, M.; Syed, A.; Prybilla, D. Immunocompetence of the severely injured spleen verified by differential interference contrast microscopy: The red blood cell pit test. J. Trauma 63(5):1087-1091; 2007.
7. Fang, B.; Shi, M.; Liao, L.; Yang, S.; Liu, Y.; Zhao, R. C. Systemic infusion of FLK1(+) mesenchymal stem cells ameliorate carbon tetrachloride-induced liver fibrosis in mice. Transplantation 78(1):83-88; 2004.
8. Hale, S. L.; Dai, W.; Dow, J. S.; Kloner, R. A. Mesenchymal stem cell administration at coronary artery reperfusion in the rat by two delivery routes: A quantitative assessment. Life Sci. 83(13-14):511-515; 2008.
9. Hardjo, M.; Miyazaki, M.; Sakaguchi, M.; Masaka, T.; Ibrahim, S.; Kataoka, K.; Huh, N. H. Suppression of carbon tetrachloride-induced liver fibrosis by transplantation of a clonal mesenchymal stem cell line derived from rat bone marrow. Cell Transplant. 18(1):89-99; 2009.
10. Hou, D.; Youssef, E. A.; Brinton, T. J.; Zhang, P.; Rogers, P.; Price, E. T.; Yeung, A. C.; Johnstone, B. H.; Yock, P. G.; March, K. L. Radiolabeled cell distribution after intramyocardial, intracoronary, and interstitial retrograde coronary venous delivery: Implications for current clinical trials. Circulation 112(Suppl.):I150-156; 2005.
11. Hou, M.; Yang, K. M.; Zhang, H.; Zhu, W. Q.; Duan, F. J.; Wang, H.; Song, Y. H.; Wei, Y. J.; Hu, S. S. Transplantation of mesenchymal stem cells from human bone marrow improves damaged heart function in rats. Int. J. Cardiol. 115(2):220-228; 2007.
12. Kotton, D. N.; Ma, B. Y.; Cardoso, W. V.; Sanderson, E. A.; Summer, R. S.; Williams, M. C.; Fine, A. Bone marrow-derived cells as progenitors of lung alveolar epithelium. Development 128(24):5181-5188; 2001.
13. Lee, R. H.; Pulin, A. A.; Seo, M. J.; Kota, D. J.; Ylostalo, J.; Larson, B. L.; Semprun-Prieto, L.; Delafontaine, P.; Prockop, D. J. Intravenous hMSCs improve myocardial infarction in mice because cells embolized in lung are activated to secrete the anti-inflammatory protein TSG-6. Cell Stem Cell 5(1):54-63; 2009.
14. Li, M. H.; Huang, K. L.; Wu, S. Y.; Chen, C. W.; Yan, H. C.; Hsu, K.; Hsu, C. W.; Tsai, S. H.; Chu, S. J. Baicalin attenuates air embolism-induced acute lung injury in rat isolated lungs. Br. J. Pharmacol. 157(2):244-251; 2009.
15. Liu, D. D.; Kao, S. J.; Chen, H. I. N-acetylcysteine attenuates acute lung injury induced by fat embolism. Crit. Care Med. 36(2):565-571; 2008.
16. Mazo, M.; Gavira, J. J.; Abizanda, G.; Moreno, C.; Ecay, M.; Soriano, M.; Aranda, P.; Collantes, M.; Alegria, E.; Merino, J. Penuelas, I. N.; Verdugo, J. M.; Pelacho, B.; Prosper, F. Transplantation of mesenchymal stem cells exerts a greater long-term effect than bone marrow mononuclear cells in a chronic myocardial infarction model in rat. Cell Transplant. 19(3):313-328; 2010.
17. Nesselmann, C.; Ma, N.; Bieback, K.; Wagner, W.; Ho, A.; Konttinen, Y. T.; Zhang, H.; Hinescu, M. E.; Steinhoff, G. Mesenchymal stem cells and cardiac repair. J. Cell. Mol. Med. 12(5B):1795-1810; 2008.
18. Ramos, G. A.; Hare, J. M. Cardiac cell-based therapy: Cell types and mechanisms of actions. Cell Transplant. 16(9):951-961; 2007.
19. Rojas, M.; Xu, J.; Woods, C. R.; Mora, A. L.; Spears, W.; Roman, J.; Brigham, K. L. Bone marrow-derived mesenchymal stem cells in repair of the injured lung. Am. J. Respir. Cell Mol. Biol. 33(2):145-152; 2005.
20. Russo, F. P.; Alison, M. R.; Bigger, B. W.; Amofah, E.; Florou, A.; Amin, F.; Bou-Gharios, G.; Jeffery, R.; Iredale, J. P.; Forbes, S. J. The bone marrow functionally contributes to liver fibrosis. Gastroenterology 130(6): 1807-1821; 2006.
21. Song, P.; Zhang, H.; Lu, M. J.; Li, J.; Liu, X. W.; Wei, Y. J.; Hu, S. S. Role of cardiopulmonary bypass and arrested heart status in the early cell distribution after intracoronary infusion of bone marrow stromal cells. J. Surg. Res. 153(1):66-70; 2009.
22. Taussig, M. J. Molecular genetics of immunoglobulins. Immunol. Suppl. 1:7-15; 1988.
23. Vassilopoulos, G.; Wang, P. R.; Russell, D. W. Transplanted bone marrow regenerates liver by cell fusion. Nature 422(6934):901-904; 2003.
24. Wang, X.; Montini, E.; Al-Dhalimy, M.; Lagasse, E.; Finegold, M.; Grompe, M. Kinetics of liver repopulation after bone marrow transplantation. Am. J. Pathol. 161(2): 565-574; 2002.
25. Yndestad, A.; Damas, J. K.; Oie, E.; Ueland, T.; Gullestad, L.; Aukrust, P. Systemic inflammation in heart failure - the whys and wherefores. Heart Fail. Rev. 11(1):83-92; 2006.
26. Zhang, H.; Fazel, S.; Tian, H.; Mickle, D. A.; Weisel, R. D.; Fujii, T.; Li, R. K. Increasing donor age adversely impacts beneficial effects of bone marrow but not smooth muscle myocardial cell therapy. Am. J. Physiol. Heart Circ. Physiol. 289(5):H2089-2096; 2005.
27. Zhang, H.; Song, P.; Tang, Y.; Zhang, X. L.; Zhao, S. H.; Wei, Y. J.; Hu, S. S. Injection of bone marrow mesenchymal stem cells in the borderline area of infarcted myocardium: Heart status and cell distribution. J. Thorac. Cardiovasc. Surg. 134(5):1234-1240; 2007.
28. Zhang, H.; Zhu, S. J.; Wang, W.; Wei, Y. J.; Hu, S. S. Transplantation of microencapsulated genetically modified xenogeneic cells augments angiogenesis and improves heart function. Gene Ther. 15(1):40-48; 2008.