From hair to cornea: Toward the therapeutic use of hair follicle-derived stem cells in the treatment of limbal stem cell deficiency

Stem Cells

Volumn 29, Issue 1, 2011, Pages 57-66

  Meyer Blazejewska, Ewa Anna ^a,b   Call, Mindy K ^b   Yamanaka, Osamu ^b,c   Liu, Hongshan ^b   Schlötzer Schrehardt, Ursula ^a   Kruse, Friedrich E ^a   Kao, Winston W ^b  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^b UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^c WAKAYAMA MEDICAL UNIVERSITY   (Japan)

Author keywords

Adult stem cells; In vivo tracking; Plasticity; Reprogramming; Stem cell plasticity; Stem cell transplantation; Stem cell microenvironment interactions; Transgenic mouse

Indexed keywords

FIBRIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL TRANSDIFFERENTIATION; CLONAL SPECIES; CONTROLLED STUDY; CORNEA CELL; CORNEA VASCULARIZATION; EPITHELIUM CELL; EYE DISEASE; LIMBAL STEM CELL DEFICIENCY; MOUSE; NONHUMAN; PHENOTYPE; STEM CELL EXPANSION; STEM CELL NICHE; STEM CELL TRANSPLANTATION; TRANSGENIC MOUSE;

ANIMALS; CELL TRANSDIFFERENTIATION; CELLS, CULTURED; CORNEAL DISEASES; EPITHELIUM, CORNEAL; EYE ABNORMALITIES; HAIR FOLLICLE; HUMANS; LIMBUS CORNEAE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; STEM CELL TRANSPLANTATION; STEM CELLS; VIBRISSAE;

ANIMALIA; MURINAE; MUS; MUS MUSCULUS;

EID: 79951821195     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1002/stem.550     Document Type: Article

References (42)

1. Polak JM, Bishop AE. Stem cells and tissue engineering: Past, present, and future. Ann N Y Acad Sci 2006;1068:352-366. (Pubitemid 43824168)
2. Cotsarelis G, Cheng SZ, Dong G et al. Existence of slow-cycling limbal epithelial basal cells that can be preferentially stimulated to proliferate: Implications on epithelial stem cells. Cell 1989;57:201-209. (Pubitemid 19112360)
3. Li W, Hayashida Y, Chen YT et al. Niche regulation of corneal epithelial stem cells at the limbus. Cell Res 2007;17:26-36. (Pubitemid 46096421)
4. Li DQ, Tseng SC. Three patterns of cytokine expression potentially involved in epithelial-fibroblast interactions of human ocular surface. J Cell Physiol 1995;163:61-79.
5. Ihanamaki T, Pelliniemi LJ, Vuorio E. Collagens and collagen-related matrix components in the human and mouse eye. Prog Retin Eye Res 2004;23:403-434. (Pubitemid 38829450)
6. Schlotzer-Schrehardt U, Dietrich T, Saito K et al. Characterization of extracellular matrix components in the limbal epithelial stem cell compartment. Exp Eye Res 2007;85:845-860. (Pubitemid 350166371)
7. Pellegrini G, Traverso CE, Franzi AT et al. Long-term restoration of damaged corneal surfaces with autologous cultivated corneal epithelium. Lancet 1997;349:990-993. (Pubitemid 27149803)
8. Shortt AJ, Secker GA, Notara MD et al. Transplantation of ex vivo cultured limbal epithelial stem cells: A review of techniques and clinical results. Surv Ophthalmol 2007;52:483-502. (Pubitemid 47268554)
9. Inatomi T, Nakamura T, Koizumi N et al. Midterm results on ocular surface reconstruction using cultivated autologous oral mucosal epithelial transplantation. Am J Ophthalmol 2006;141:267-275.
10. Cotsarelis G, Sun TT, Lavker RM. Label-retaining cells reside in the bulge area of pilosebaceous unit: Implications for follicular stem cells, hair cycle, and skin carcinogenesis. Cell 1990;61:1329-1337.
11. Jahoda CA, Whitehouse J, Reynolds AJ et al. Hair follicle dermal cells differentiate into adipogenic and osteogenic lineages. Exp Dermatol 2003;12:849-859. (Pubitemid 38028676)
12. Lako M, Armstrong L, Cairns PM et al. Hair follicle dermal cells repopulate the mouse haematopoietic system. J Cell Sci 2002;115(part 20):3967-3974. (Pubitemid 35256497)
13. Richardson GD, Arnott EC, Whitehouse CJ et al. Plasticity of rodent and human hair follicle dermal cells: Implications for cell therapy and tissue engineering. J Investig Dermatol Symp Proc 2005;10:180-183.
14. Cotsarelis G. Epithelial stem cells: A folliculocentric view. J Invest Dermatol 2006;126:1459-1468.
15. Taylor G, Lehrer MS, Jensen PJ et al. Involvement of follicular stem cells in forming not only the follicle but also the epidermis. Cell 2000;102:451-461.
16. Kloepper JE, Tiede S, Brinckmann J et al. Immunophenotyping of the human bulge region: The quest to define useful in situ markers for human epithelial hair follicle stem cells and their niche. Exp Dermatol 2008;17:592-609. (Pubitemid 351803082)
17. Tiede S, Kloepper JE, Bodo E et al. Hair follicle stem cells: Walking the maze. Eur J Cell Biol 2007;86:355-376. (Pubitemid 46971920)
18. Larouche D, Tong X, Fradette J et al. Vibrissa hair bulge houses two populations of skin epithelial stem cells distinct by their keratin profile. FASEB J 2008;22:1404-1415. (Pubitemid 351656781)
19. Blazejewska EA, Schlotzer-Schrehardt U, Zenkel M et al. Corneal limbal microenvironment can induce transdifferentiation of hair follicle stem cells into corneal epithelial-like cells. Stem Cells 2009;27:642-652.
20. Chikama T, Hayashi Y, Liu CY et al. Characterization of tetracycline-inducible bitransgenic Krt12rtTA/+/tet-O-LacZ mice. Invest Ophthalmol Vis Sci 2005;46:1966-1972.
21. Perl AK, Wert SE, Nagy A et al. Early restriction of peripheral and proximal cell lineages during formation of the lung. Proc Natl Acad Sci USA 2002;99:10482-10487.
22. Muzumdar MD, Tasic B, Miyamichi K et al. A global double-fluorescent Cre reporter mouse. Genesis 2007;45:593-605. (Pubitemid 350013057)
23. Pellegrini G, Ranno R, Stracuzzi G et al. The control of epidermal stem cells (holoclones) in the treatment of massive full-thickness burns with autologous keratinocytes cultured on fibrin. Transplantation 1999;68:868-879. (Pubitemid 29468207)
24. Bagutti C, Wobus AM, Fassler R et al. Differentiation of embryonal stem cells into keratinocytes: Comparison of wild-type and beta 1 integrin-deficient cells. Dev Biol 1996;179:184-196. (Pubitemid 26363256)
25. Lavker RM, Sun TT. Epidermal stem cells: Properties, markers, and location. Proc Natl Acad Sci USA 2000;97:13473-13475.
26. Jensen UB, Yan X, Triel C et al. A distinct population of clonogenic and multipotent murine follicular keratinocytes residing in the upper isthmus. J Cell Sci 2008;121(part 5):609-617. (Pubitemid 351524159)
27. Barrandon Y, Green H. Three clonal types of keratinocyte with different capacities for multiplication. Proc Natl Acad Sci USA 1987;84:2302-2306. (Pubitemid 17075859)
28. Blanpain C, Lowry WE, Geoghegan A et al. Self-renewal, multipotency, and the existence of two cell populations within an epithelial stem cell niche. Cell 2004;118:635-648. (Pubitemid 39179715)
29. Hayashi Y, Call M, Liu CY et al. Monoallelic Expression of Krt12 gene during corneal-type epithelium differentiation of limbal stem cells. Invest Ophthalmol Vis Sci 2010;51:4562-4568.
30. Chaloin-Dufau C, Pavitt I, Delorme P et al. Identification of keratins 3 and 12 in corneal epithelium of vertebrates. Epithelial Cell Biol 1993;2:120-125. (Pubitemid 23212605)
31. Leigh IM, Purkis PE, Whitehead P et al. Monospecific monoclonal antibodies to keratin 1 carboxy terminal (synthetic peptide) and to keratin 10 as markers of epidermal differentiation. Br J Dermatol 1993;129:110-119. (Pubitemid 23250719)
32. Ang LP, Tan DT, Beuerman RW et al. Development of a conjunctival epithelial equivalent with improved proliferative properties using a multistep serum-free culture system. Invest Ophthalmol Vis Sci 2004;45:1789-1795. (Pubitemid 38868973)
33. Hodgkinson T, Yuan XF, Bayat A. Adult stem cells in tissue engineering. Expert Rev Med Devices 2009;6:621-640.
34. Sakaguchi Y, Sekiya I, Yagishita K et al. Comparison of human stem cells derived from various mesenchymal tissues: Superiority of synovium as a cell source. Arthritis Rheum 2005;52:2521-2529. (Pubitemid 41117441)
35. Kern S, Eichler H, Stoeve J et al. Comparative analysis of mesenchymal stem cells from bone marrow, umbilical cord blood, or adipose tissue. Stem Cells 2006;24:1294-1301. (Pubitemid 44464698)
36. MacNeil S. Progress and opportunities for tissue-engineered skin. Nature 2007;445:874-880.
37. Lenoir MC, Bernard BA, Pautrat G et al. Outer root sheath cells of human hair follicle are able to regenerate a fully differentiated epidermis in vitro. Dev Biol 1988;130:610-620. (Pubitemid 19016097)
38. Gharzi A, Reynolds AJ, Jahoda CA. Plasticity of hair follicle dermal cells in wound healing and induction. Exp Dermatol 2003;12:126-136. (Pubitemid 36934697)
39. Ferraris C, Chevalier G, Favier B et al. Adult corneal epithelium basal cells possess the capacity to activate epidermal, pilosebaceous and sweat gland genetic programs in response to embryonic dermal stimuli. Development 2000;127:5487-5495. (Pubitemid 32049201)
40. Pearton DJ, Ferraris C, Dhouailly D. Transdifferentiation of corneal epithelium: Evidence for a linkage between the segregation of epidermal stem cells and the induction of hair follicles during embryogenesis. Int J Dev Biol 2004;48:197-201. (Pubitemid 38807934)
41. Guilak F, Cohen DM, Estes BT et al. Control of stem cell fate by physical interactions with the extracellular matrix. Cell Stem Cell 2009;5:17-26.
42. Estes BT, Gimble JM, Guilak F. Mechanical signals as regulators of stem cell fate. Curr Top Dev Biol 2004;60:91-126. (Pubitemid 39752360)