ESR, CALCR and VDR gene polymorphisms and their relation to bone mineral density, bone turnover markers and incidence of fractures in Slovak osteoporotic women;Vzt'ah polymorfizmov v ESR, CALCR a VDR génoch k hustote kostného minerálu, markerom kostného obratu a výskytu fraktúr v populácii slovenských osteoporotických žien

Osteologicky Bulletin

Volumn 15, Issue 4, 2010, Pages 156-164

  Galbavy D ^a   Omelka, R ^a   Bauerova M ^a   Hunak O ^a  

^a Nemocnica Topol'čany ^*  (Slovakia)

Author keywords

Bone mineral density; Candidate genes; Fracture; Osteoporosis

Indexed keywords

ALKALINE PHOSPHATASE; BIOLOGICAL MARKER; CALCITONIN RECEPTOR; ESTROGEN RECEPTOR; OSTEOCALCIN; VITAMIN D RECEPTOR;

ADULT; AGE; AGED; ALKALINE PHOSPHATASE BLOOD LEVEL; ARTICLE; BONE DENSITY; BONE TURNOVER; FEMALE; FEMUR; FRAGILITY FRACTURE; GENETIC LINKAGE; GENOTYPE; HUMAN; LUMBAR VERTEBRA; MAJOR CLINICAL STUDY; MORBIDITY; OSTEOPOROSIS; POLYMERASE CHAIN REACTION; PROTEIN BLOOD LEVEL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SLOVAKIA; STATISTICAL ANALYSIS;

EID: 79951820077     PISSN: 12113778     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (46)

1. Štěpán J. Syndrom osteoporózy. Thomayerova sbírka, Praha, Avicenum, 1988.
2. Sršeň Š, Srašňová K. Základy klinickej genetiky. Martin, Osveta, 2000.
3. Riggs BL, Melton LJ. Involutional Osteoporosis. New Engl J Med 1986; 314: 1676-1686.
4. Mazess RB et al. Etiology of Osteoporosis. Bone Mineral 1987;15:211.
5. Arden NK, Baker J, Hogg C et al. The Heritability of Bone Mineral Density Ultrasound of The Calcaneus and Hip Axis Length: A Study of Postmenopausal Twins. J Bone Miner Res 1996;11:530-534. (Pubitemid 26109073)
6. Morrison NA, Baker A et al. ApaI Dimorphism At The Human Vitamin D Receptor Gene Locus. Nucleic Acids Research 1989;17:2150-2155.
7. Menasce LP, White GR, Harrison CJ et al. Localization of The Estrogen Receptor Locus To Chromosome 6q25.1 By FISH and a Simple Post-FISH Banding Technique. Genomics 1993;17:263-265. (Pubitemid 23205095)
8. Kobayashi S, Inoue S, Hosi T et al. Association of Bone Mineral Density With Polymorphism of The Estrogen Receptor Gene. Journal of Bone And Mineral Research 1996;11:306-311. (Pubitemid 26076380)
9. Nakamura M, Zhang Z, Shan L et al. Allelic Variants of Human Calcitonin Receptor In The Japanese Population. Human Genetics 1997;99:38-41. (Pubitemid 26419852)
10. Sambrook J, Fritsch EF, Maniatis T. Molecular Cloning: A Laboratory Manual. Cold-Spring Harbor Lab., New York 1989, p 1626.
11. Harris SS, Eccleshall TR, Gross C et al. The Vitamin D Receptor Start Codon Polymorphism (FokI) and BMD In Premenopausal American Black and White Women. J Bone Miner Res 1997;12:1043-1048. (Pubitemid 27264217)
12. Masi L et al. Polymorphisms of The Calcitonin Receptor Gene Are Associated With Bone Mineral Density In Postmenopausal Italian Women. Biochemistry and Biophysiology Research Communications 1998;248:190-195. (Pubitemid 28418210)
13. Albagha OME, McGuigan FE, Reid DM et al. Estrogen Receptor Alpha Gene Polymorphisms and Bone Mineral Density. J Bone Miner Res 2001;16:128-134.
14. Becherini L, Gennari L, Masi L et al. Evidence of A Linkage Disequilibrium Between Polymorphisms In The Human ESR1 Gene and Their Relationship To Bone Mass Variation In Postmenopausal Italian Women Hum Mol Genet 2000;9:2043-2050.
15. Zajíčková K, Žofková I et al. Osteoporosis: Genetic Analysis of Multifactorial Disease. Endocr Regul 2003;37:31-44. (Pubitemid 36534633)
16. Jakimiuk AJ, Nowicka M, Adamiak A et al. Prevalence of ESR1 PvuII and XbaI Polymorphism In Population of Polish Postmenopausal Women. Fol Histochem Et Cytobiol 2007;4:331-338. (Pubitemid 351193606)
17. Ivanova JT, Doukova PB, Boyanov MA et al. PvuII and XbaI Polymorphisms of The ER Gene and BMD I Bulgarian Population Sample Hormones 2007;6:36-43.
18. Sapir-Koren R, Livshits G, Kobyliansky E. Associations and Linkage Disequilibrium Analysis Suggest Genetic Effects of ESR1 and COL1A1 Genes On BMD In Caucasian Women. Calcif Tissue Int 2003;72:643-650. (Pubitemid 36917317)
19. Bagger YZ, Jorgensen HL, Heegard AM et al. No Major Effect of ER Gene Polymorphisms On BMD of Bone Loss In Postmenopausal Danish Women. Bone 2000;26:111-116. (Pubitemid 30029202)
20. Van Meurs JB, Schutt SC, Weel AE et al. Associations of 5′ ESR1 Gene Polymorphisms With BMD, Vertebral Bone Area and Fracture Risk. Human Mol Genet 2003;12:1745-1754.
21. Gennari L, Merlotti D, De Pala V et al. ER Gene Polymorphisms and The Genetics of Osteoporosis. Am Journal of Epidemiol 2005;161:307-320.
22. Taboulet J, Frenkian M, Frendo J et al. Calcitonin Receptor Polymorphism Is Associated With A Decreased Fracture Risk In Postmenopausal Women. Human Molecular Genetics 1998;7:2129-2133. (Pubitemid 28546423)
23. Braga V, Sangalli A, Malerba G et al. Relationship Amng VDR (BsmI and FokI), COL1A1 and CALCR Polymorphisms With Bone Mass, Bone Turnover Markers and Sex Hormones In Men. Calcif Tissue Int 2002;70:457-462.
24. Žofková I, Zajíčková K, Hill M et al. Does Polymorphism C1377T of The CALCR Gene Determine BMD In Postmenopausal Women? Exp Clin Endocrinol Diabetes 2003;111:447.
25. Drews K et al. Genetic Polymorphism of The Calcitonin Receptor Gene and Bone Mineral Density In Polish Population of Postmenopausal Women. Gynekol Pol 2005;76:612-618.
26. Morita A, Iki M, Dohi Y et al. Prediction of BMD From VDR Polymorphisms Is Uncertain In Representative Samples of Japanese Women. Int Journal o Epidemiol 2004;33:979-988.
27. Wengreen H et al. Vitamin D Receptor Genotype and Risk of Osteoporotic Hip Fracture In Elderly Women of Utah. Osteoporosis International 2006;7:286-299.
28. MacDonald HM, McGiugan FE, Stewart A et al. Large-Scale Population-Based Study Shows No Evidence of Association Between Common Polymorphism of The VDR Gene and BMD In British Women. J Bone Miner Res2006;21:151-162.
29. Bustamante M, Nogués X, Enjuanes A et al. COL1A1, ESR, VDR and TGFB1 Polymorphisms and Haplotypes In Relation To BMD In Spanish Postmenopausal Women. Osteoporosis Int 2007;18:235-243. (Pubitemid 46090226)
30. Falchtetti A, Sferzza C, Cepollaro C et al. FokI Polymorphism of The Vitami D Receptor Gene Correlates With Parameters of Bone Mass and Turnover In A Female Population of The Italian Island of Lampedusa. Calcif Tissue Int 2007;80:15-20. (Pubitemid 46095746)
31. Zajíčková K, Žofková I. Osteoporosis: Genetic Analysis of Multifactorial Disease. Endocrinology Regulation 2003;37:31-44.
32. Willing MC, Sowers M, Aran D et al. Bone Mineral Density and Its Change In White Women: Estrogen and Vitamin D Receptor Genotypes and Their Interaction. J Bone Miner Res 1998;13:695-705. (Pubitemid 28163021)
33. Rapury PB et al. ESR alpha Gene Polymorphisms Are Associated With Changes In Bone Remodeling Markers and Treatment Response To Estrogen. Maturitas 2006;53:371-379.
34. McClure L et al. Vitamin D Receptor Polymorphisms, BMD and Bone Metabolism In Postmenopausal Mexican-American Women. J Bone Miner Res 1997;12:234-240. (Pubitemid 27086304)
35. Aerssens J, Dequeker J, Peeters J et al. Polymorphisms of The VDR, ER and COL1A1 Genes and Osteoporotic Hip Fracture In Elderly Postmenopausal Women. Osteoporosis International 2000;11:583-591.
36. Salmen T, Heikkinen AM, Mahonen A et al. Early Postmenopausal Bone Loss Is Associated With Pvu II ER Gene Plymorphism In Finish Women. J Bone Miner Res 2000;15:315-321.
37. Ioannidis JP, Stavrou I, Zois C et al. Associations of Polymorphisms of The ESR1 Gene With BMD and Fracture Risk in Women. J Bone Miner Res 2002;17:2048-2060.
38. Grendale GA, Barrett-Connor E, Edelstein S et al. Lifetime Leisure Exercise and Osteoporosis. American Journal of Epidemiology 2006;14:951-959.
39. Zhang YY, Long JR, Liu PY et al. Er and VDR Gene Polymorphisms and BMD: Association Study of Healthy Pre and Postmenopausal Chinese Women. Biochem Biophys Res Commun 2003;308:777-783.
40. Wood RJ et al. The Genetics of Osteoporosis Vitamin D Receptor Polymorphisms 1998;18:233-258.
41. Lisker R, Lopez MA, Jasqui S. Association of VDR Polymorphisms With Osteoporosis In Mexican Postmenopausal Women. Humn Biology 2003;75:399-403. (Pubitemid 37127691)
42. Langdahl BL et al. A TA Repeat Polymorphism In The Estrogen Receptor Gene Is Associated With Osteoporotic Fractures But Polymorphisms In The First Exon and Intron Are Not. J Bone Miner Res 2000;15:2222-2230.
43. Vandevyver C et al. Lack of Association Between Estrogen Receptor Genotypes and Bone Mineral Density, Fracture History or Muscle Strength In Elderly Women. J Bone Miner Res 1999;14:1576-1582. (Pubitemid 29416685)
44. Moffett SP, Dillon KA, Yerpes LA et al. Identification and Association Analysis of SNP In The Human Gene and Osteoporosis Phenotypes. Bone 2009;44:999-1002.
45. Horst-Sikorska V, Wawrzyniika A, Marcinkowska M et al. VDR Gene Polymorphisms As Indicator of Alendronate Therapy Postmenopausal Osteoporotic Women Effectiveness. Osteoporosis International 2009;20:121.
46. Bolu SE, Orkunogluf E, Deniz F et al. The VDR FokI Start Codon Polymorphism and BMD In Male Hypogonadism. Journal of Endocrinol Invest 2005;9:345-351.