Comparison of the NIDS® rapid assay with ELISA methods in immunogenicity testing of two biotherapeutics

Journal of Pharmacological and Toxicological Methods

Volumn 63, Issue 2, 2011, Pages 150-159

  Pan, Jing ^a   Small, Thomas ^a   Qin, Dujie ^a   Li, Shawn ^a   Wang, Li ^a   Chen, Dave ^a   Pauley, Cindy ^b   Verch, Thorsten ^b   Kaplanski, Catherine ^b   Bakhtiar, Ray ^b   Vallejo, Yli Remo ^a   Yin, Ray ^a  

^a ANP Technologies Inc   (United States)

^b MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Anti drug antibody (ADA); Biotherapeutic antibodies; ELISA; Immunogenicity assay methods; Lateral flow assay; Rapid assay

Indexed keywords

BIOTIN; DRUG ANTIBODY; EPIDERMAL GROWTH FACTOR RECEPTOR ANTIBODY; GOLD; HAPTEN; STREPTAVIDIN; TUMOR NECROSIS FACTOR ALPHA ANTIBODY;

ANTIBODY DETECTION; ANTIGEN BINDING; ARTICLE; BINDING AFFINITY; BIOTINYLATION; BLOOD SAMPLING; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FALSE NEGATIVE RESULT; FALSE POSITIVE RESULT; HUMAN; IMMUNOASSAY; IMMUNOGENICITY; INTERMETHOD COMPARISON; MAJOR CLINICAL STUDY; NANO INTELLIGENT DETECTION SYSTEM; QUANTITATIVE ANALYSIS; RHEUMATOID ARTHRITIS;

ANTIBODIES; ANTIBODY FORMATION; ARTHRITIS, RHEUMATOID; DOSE-RESPONSE RELATIONSHIP, IMMUNOLOGIC; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; IMMUNOGENETICS; RECEPTOR, ERBB-2; TUMOR NECROSIS FACTOR-ALPHA;

EID: 79951813133     PISSN: 10568719     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vascn.2010.09.003     Document Type: Article

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