Massive parallel amplicon sequencing of the breast cancer genes BRCA1 and BRCA2: Opportunities, challenges, and limitations

Human Mutation

Volumn 32, Issue 3, 2011, Pages 335-344

  De Leeneer, Kim ^a   Hellemans, Jan ^a   De Schrijver, Joachim ^b   Baetens, Machteld ^a   Poppe, Bruce ^a   Van Criekinge, Wim ^b   De Paepe, Anne ^a   Coucke, Paul ^a   Claes, Kathleen ^a  

^a GHENT UNIVERSITY HOSPITAL   (Belgium)

^b GHENT UNIVERSITY   (Belgium)

Author keywords

Amplicon sequencing; Barcoding; BRCA1; BRCA2; Massive parallel sequencing; Multiplex

Indexed keywords

BRCA1 PROTEIN; BRCA2 PROTEIN; NUCLEOTIDE;

AMPLICON; ARTICLE; BREAST CANCER; CANCER RISK; CLINICAL ARTICLE; CONTROLLED STUDY; DNA SEQUENCE; FEMALE; GENE AMPLIFICATION; GENE DELETION; GENE DUPLICATION; GENETIC SCREENING; HUMAN; PARALLEL DESIGN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PSEUDOGENE; PYROSEQUENCING; TUMOR GENE; TURNAROUND TIME;

BASE SEQUENCE; BRCA1 PROTEIN; BRCA2 PROTEIN; BREAST NEOPLASMS; DNA MUTATIONAL ANALYSIS; FEMALE; GENES, BRCA1; GENES, BRCA2; GENETIC PREDISPOSITION TO DISEASE; GENETIC TESTING; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; SENSITIVITY AND SPECIFICITY; SEQUENCE ANALYSIS, DNA;

EID: 79951805438     PISSN: 10597794     EISSN: 10981004     Source Type: Journal    
DOI: 10.1002/humu.21428     Document Type: Article

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