NSD1 PHD domains bind methylated H3K4 and H3K9 using interactions disrupted by point mutations in human sotos syndrome

Human Mutation

Volumn 32, Issue 3, 2011, Pages 292-298

  Pasillas, Martina P ^a   Shah, Meera ^b   Kamps, Mark P ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b BURNHAM INSTITUTE   (United States)

Author keywords

Epigenetics; Histone methylation; NSD1; PHD domain; Sotos syndrome

Indexed keywords

HISTONE H3; HISTONE H4; LYSINE;

ARTICLE; EPIGENETICS; GENE DELETION; GENE MUTATION; HUMAN; METHYLATION; PHENOTYPE; POINT MUTATION; PRIORITY JOURNAL; PROTEIN DOMAIN; REGULATORY MECHANISM; SOTOS SYNDROME; TRANSCRIPTION REGULATION;

HAPLOINSUFFICIENCY; HISTONES; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; METHYLATION; NUCLEAR PROTEINS; POINT MUTATION; PROTEIN INTERACTION DOMAINS AND MOTIFS; RECOMBINANT FUSION PROTEINS; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS, PROTEIN; SOTOS SYNDROME; TRANSCRIPTION FACTORS; UBIQUITINATION;

EID: 79951792080     PISSN: 10597794     EISSN: 10981004     Source Type: Journal    
DOI: 10.1002/humu.21424     Document Type: Article

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