Drug safety in pregnancy: Utopia or achievable prospect? Risk information, risk research and advocacy in Teratology Information Services

Congenital Anomalies

Volumn 51, Issue 1, 2011, Pages 6-11

  Schaefer, Christof ^a  

^a Berlin Institute for Clinical Teratology   (Germany)

Author keywords

Drug; Human; Observational study; Pregnancy; Teratology information service

Indexed keywords

ACENOCOUMAROL; ANGIOTENSIN 2 RECEPTOR ANTAGONIST; ANTIVITAMIN K; FLUINDIONE; HAIR DYE; HOMEOPATHIC AGENT; HYDRALAZINE; ISOTRETINOIN; METHYLDOPA; METOPROLOL; NIFEDIPINE; PARACETAMOL; PHENINDIONE; PHENPROCOUMON; THALIDOMIDE; WARFARIN;

ACNE; ANURIA; BIRTH DEFECT; CONTROLLED CLINICAL TRIAL (TOPIC); COST CONTROL; COUNSELING; DRUG FATALITY; DRUG SAFETY; FEMALE; FOLLOW UP; HEALTH CARE POLICY; HEART VENTRICLE SEPTUM DEFECT; HUMAN; INFORMATION PROCESSING; INTERPERSONAL COMMUNICATION; INTERVIEW; LUNG HYPOPLASIA; MEDICAL INFORMATION SYSTEM; MULTICENTER STUDY (TOPIC); OLIGOHYDRAMNIOS; PHILOSOPHY; PREGNANCY; PRENATAL EXPOSURE; PRIORITY JOURNAL; REVIEW; RISK ASSESSMENT; SIDE EFFECT; SPONTANEOUS ABORTION; STRUCTURED QUESTIONNAIRE; TERATOGENESIS; TERATOLOGY;

4-HYDROXYCOUMARINS; ABNORMALITIES, DRUG-INDUCED; ANGIOTENSIN RECEPTOR ANTAGONISTS; ANTICOAGULANTS; DRUG INFORMATION SERVICES; FEMALE; HUMANS; PREGNANCY; PREGNANCY COMPLICATIONS; RETINOIDS; RISK ASSESSMENT; TERATOLOGY; VITAMIN K;

EID: 79951789734     PISSN: 09143505     EISSN: 17414520     Source Type: Journal    
DOI: 10.1111/j.1741-4520.2010.00308.x     Document Type: Review

References (12)

1. Barr M (1994) Teratogen update: angiotensin-converting enzyme inhibitors. Teratology 50: 399-409.
2. Bower C, Rudy E, Callaghan A, Quick J, Nassar N (2010) Age at diagnosis of birth defects. Birth Defects Res A 88: 251-255.
3. Dai WS, LaBraico JM, Stern RS (1992) Epidemiology of isotretinoin exposure during pregnancy. J Am Acad Dermatol 26: 599- 606.
4. Hall JG, Pauli RM, Wilson KM (1980) Maternal and fetal sequelae of anticoagulation during pregnancy. Am J Med 68: 122-140.
5. Hancock RL, Koren G, Einarson A, Ungar WJ (2007) The effectiveness of Teratology Information Services (TIS). Reprod Toxicol 23: 125-132.
6. Howe AM, Webster WS (1992) The warfarin embryopathy: a rat model showing maxillonasal hypoplasia and other skeletal disturbances. Teratology 46: 379-390.
7. Jones KL, Johnson DL, Chambers CD (2002) Monitoring leflunomide (Arava) as a new potential teratogen. Teratology 65: 200-202.
8. Lammer EJ, Chen DT, Hoar RM etal. (1985) Retinoic acid embryopathy. N Engl J Med 313: 837-841.
9. Meister R, Schaefer C (2008) Statistical methods for estimating the probability of spontaneous abortion in observational studies - analyzing pregnancies exposed to coumarin derivatives. Reprod Toxicol 26: 31-35.
10. Schaefer C, Hannemann D, Meister R (2005) Post-marketing surveillance system for drugs in pregnancy - 15years experience of ENTIS. Reprod Toxicol 20: 331-343.
11. Schaefer C, Hannemann D, Meister R etal. (2006) Vitamin K antagonists and pregnancy outcome. A multi-centre prospective study. Thromb Haemost 95: 949-957.
12. Schaefer C, Meister R, Weber-Schoendorfer C (2009) Isotretinoin exposure and pregnancy outcome - an observational study of the Berlin institute for clinical teratology and drug risk assessment during pregnancy. Arch Gynecol Obstet 281: 221-227.