Methylenetetrahydrofolate reductase C677T polymorphism in patients with lung cancer in a Korean population

BMC Medical Genetics

Volumn 12, Issue , 2011, Pages

  Cui, Lian Hua ^a   Shin, Min Ho ^b   Kim, Hee N ^c   Song, Hye Rim ^b   Piao, Jin Mei ^b,d   Kweon, Sun Seog ^b,c   Choi, Jin Su ^b   Yun, Woo Jun ^b   Kim, Young Chul ^b   Oh, In Jae ^b   Kim, Kyu Sik ^b  

^a QINGDAO UNIVERSITY MEDICAL COLLEGE   (China)

^b Chonnam National University Medical School   (South Korea)

^c Chonnam National University Hwasun Hospital and Medical School   (South Korea)

^d YANBIAN UNIVERSITY MEDICAL COLLEGE   (China)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; METHYLENETETRAHYDROFOLATE REDUCTASE (NADPH2); PRIMER DNA;

ADULT; AGE DISTRIBUTION; AGED; ARTICLE; CANCER DIAGNOSIS; CANCER RISK; CASE CONTROL STUDY; CONTROLLED STUDY; DIAGNOSTIC TEST ACCURACY STUDY; DNA EXTRACTION; FEMALE; GENDER; GENE FREQUENCY; GENETIC ASSOCIATION; GENOTYPE; HETEROZYGOSITY; HISTOPATHOLOGY; HOMOZYGOSITY; HUMAN; HUMAN TISSUE; KOREA; LARGE CELL CARCINOMA; LOGISTIC REGRESSION ANALYSIS; LUNG ADENOCARCINOMA; LUNG CANCER; LUNG SMALL CELL CANCER; LUNG SQUAMOUS CELL CARCINOMA; MAJOR CLINICAL STUDY; MALE; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; RISK ASSESSMENT; SINGLE NUCLEOTIDE POLYMORPHISM; SMOKING HABIT; ADENOCARCINOMA; ALLELE; CONFIDENCE INTERVAL; ENZYMOLOGY; GENETIC PREDISPOSITION; GENETICS; LUNG TUMOR; MIDDLE AGED; NUCLEOTIDE SEQUENCE; RISK; RISK FACTOR; SOUTH KOREA; SQUAMOUS CELL CARCINOMA;

ADENOCARCINOMA; AGED; ALLELES; BASE SEQUENCE; CARCINOMA, LARGE CELL; CARCINOMA, SQUAMOUS CELL; CASE-CONTROL STUDIES; CONFIDENCE INTERVALS; DNA PRIMERS; DNA, NEOPLASM; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; HUMANS; LUNG NEOPLASMS; MALE; METHYLENETETRAHYDROFOLATE REDUCTASE (NADPH2); MIDDLE AGED; ODDS RATIO; POLYMORPHISM, SINGLE NUCLEOTIDE; REPUBLIC OF KOREA; RISK FACTORS; SMALL CELL LUNG CARCINOMA;

EID: 79951785551     PISSN: None     EISSN: 14712350     Source Type: Journal    
DOI: 10.1186/1471-2350-12-28     Document Type: Article

References (26)

1. Jee SH, Kim IS, Suh I, Shin D, Appel LJ. Projected mortality from lung cancer in South Korea, 1980-2004. Int J Epidemiol 1998, 27(3):365-369. 10.1093/ije/27.3.365, 9698121.
2. Jung KW, Park S, Kong HJ, Won YJ, Boo YK, Shin HR, Park EC, Lee JS. Cancer statistics in Korea: incidence, mortality and survival in 2006-2007. J Korean Med Sci 25(8):1113-1121. 10.3346/jkms.2010.25.8.1113, 2908777, 20676319.
3. Shin HR, Won YJ, Jung KW, Kong HJ, Yim SH, Lee JK, Noh HI, Lee JK, Pisani P, Park JG. Nationwide cancer incidence in Korea, 1999~2001; first result using the national cancer incidence database. Cancer Res Treat 2005, 37(6):325-331. 10.4143/crt.2005.37.6.325, 2785938, 19956367.
4. Mattson ME, Pollack ES, Cullen JW. What are the odds that smoking will kill you?. Am J Public Health 1987, 77(4):425-431. 10.2105/AJPH.77.4.425, 1646951, 3826460.
5. Shields PG. Molecular epidemiology of smoking and lung cancer. Oncogene 2002, 21(45):6870-6876. 10.1038/sj.onc.1205832, 12362269.
6. Shields PG, Harris CC. Cancer risk and low-penetrance susceptibility genes in gene-environment interactions. J Clin Oncol 2000, 18(11):2309-2315.
7. Jacques PF, Bostom AG, Williams RR, Ellison RC, Eckfeldt JH, Rosenberg IH, Selhub J, Rozen R. Relation between folate status, a common mutation in methylenetetrahydrofolate reductase, and plasma homocysteine concentrations. Circulation 1996, 93(1):7-9.
8. Frosst P, Blom HJ, Milos R, Goyette P, Sheppard CA, Matthews RG, Boers GJ, den Heijer M, Kluijtmans LA, van den Heuvel LP, et al. A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase. Nature genetics 1995, 10(1):111-113. 10.1038/ng0595-111, 7647779.
9. Hung RJ, Hashibe M, McKay J, Gaborieau V, Szeszenia-Dabrowska N, Zaridze D, Lissowska J, Rudnai P, Fabianova E, Mates I, et al. Folate-related genes and the risk of tobacco-related cancers in Central Europe. Carcinogenesis 2007, 28(6):1334-1340. 10.1093/carcin/bgm067, 17389614.
10. Shen M, Rothman N, Berndt SI, He X, Yeager M, Welch R, Chanock S, Caporaso N, Lan Q. Polymorphisms in folate metabolic genes and lung cancer risk in Xuan Wei, China. Lung Cancer 2005, 49(3):299-309. 10.1016/j.lungcan.2005.04.002, 15922487.
11. Siemianowicz K, Gminski J, Garczorz W, Slabiak N, Goss M, Machalski M, Magiera-Molendowska H. Methylenetetrahydrofolate reductase gene C677T and A1298C polymorphisms in patients with small cell and non-small cell lung cancer. Oncol Rep 2003, 10(5):1341-1344.
12. Zhang XM, Miao XP, Tan W, Qu SN, Sun T, Zhou YF, Lin DX. Association between genetic polymorphisms in methylentetrahydrofolate reductase and risk of lung cancer. Zhongguo Yi Xue Ke Xue Yuan Xue Bao 2005, 27(6):700-703.
13. Jeng YL, Wu MH, Huang HB, Lin WY, You SL, Chu TY, Chen CJ, Sun CA. The methylenetetrahydrofolate reductase 677C-T polymorphism and lung cancer risk in a Chinese population. Anticancer Res 2003, 23(6D):5149-5152.
14. Liu CS, Tsai CW, Hsia TC, Wang RF, Liu CJ, Hang LW, Chiang SY, Wang CH, Tsai RY, Lin CC, et al. Interaction of methylenetetrahydrofolate reductase genotype and smoking habit in Taiwanese lung cancer patients. Cancer Genomics Proteomics 2009, 6(6):325-329.
15. Suzuki T, Matsuo K, Hiraki A, Saito T, Sato S, Yatabe Y, Mitsudomi T, Hida T, Ueda R, Tajima K. Impact of one-carbon metabolism-related gene polymorphisms on risk of lung cancer in Japan: a case control study. Carcinogenesis 2007, 28(8):1718-1725. 10.1093/carcin/bgm104, 17468511.
16. Heijmans BT, Boer JM, Suchiman HE, Cornelisse CJ, Westendorp RG, Kromhout D, Feskens EJ, Slagboom PE. A common variant of the methylenetetrahydrofolate reductase gene (1p36) is associated with an increased risk of cancer. Cancer Res 2003, 63(6):1249-1253.
17. Shen H, Spitz MR, Wang LE, Hong WK, Wei Q. Polymorphisms of methylene-tetrahydrofolate reductase and risk of lung cancer: a case-control study. Cancer Epidemiol Biomarkers Prev 2001, 10(4):397-401.
18. Vineis P, Veglia F, Garte S, Malaveille C, Matullo G, Dunning A, Peluso M, Airoldi L, Overvad K, Raaschou-Nielsen O, et al. Genetic susceptibility according to three metabolic pathways in cancers of the lung and bladder and in myeloid leukemias in nonsmokers. Ann Oncol 2007, 18(7):1230-1242. 10.1093/annonc/mdm109, 17496311.
19. Kim HN, Lee IK, Kim YK, Tran HT, Yang DH, Lee JJ, Shin MH, Park KS, Shin MG, Choi JS, et al. Association between folate-metabolizing pathway polymorphism and non-Hodgkin lymphoma. Br J Haematol 2008, 140(3):287-294. 10.1111/j.1365-2141.2007.06893.x, 18042267.
20. Mao R, Fan Y, Jin Y, Bai J, Fu S. Methylenetetrahydrofolate reductase gene polymorphisms and lung cancer: a meta-analysis. J Hum Genet 2008, 53(4):340-348. 10.1007/s10038-008-0262-6, 18340404.
21. Boccia S, Boffetta P, Brennan P, Ricciardi G, Gianfagna F, Matsuo K, van Duijn CM, Hung RJ. Meta-analyses of the methylenetetrahydrofolate reductase C677T and A1298C polymorphisms and risk of head and neck and lung cancer. Cancer Lett 2009, 273(1):55-61. 10.1016/j.canlet.2008.07.026, 18789576.
22. Hao L, Ma J, Zhu J, Stampfer MJ, Tian Y, Willett WC, Li Z. High prevalence of hyperhomocysteinemia in Chinese adults is associated with low folate, vitamin B-12, and vitamin B-6 status. J Nutr 2007, 137(2):407-413.
23. Dhonukshe-Rutten RA, de Vries JH, de Bree A, van der Put N, van Staveren WA, de Groot LC. Dietary intake and status of folate and vitamin B12 and their association with homocysteine and cardiovascular disease in European populations. Eur J Clin Nutr 2009, 63(1):18-30. 10.1038/sj.ejcn.1602897, 17851461.
24. Lee HC, Jeong YM, Lee SH, Cha KY, Song SH, Kim NK, Lee KW, Lee S. Association study of four polymorphisms in three folate-related enzyme genes with non-obstructive male infertility. Hum Reprod 2006, 21(12):3162-3170. 10.1093/humrep/del280, 16861746.
25. Cui LH, Shin MH, Kweon SS, Kim HN, Song HR, Piao JM, Choi JS, Shim HJ, Hwang JE, Kim HR, et al. Methylenetetrahydrofolate reductase C677T polymorphism in patients with gastric and colorectal cancer in a Korean population. BMC Cancer 10:236. 10.1186/1471-2407-10-236, 2893109, 20504332.
26. Shi Q, Zhang Z, Li G, Pillow PC, Hernandez LM, Spitz MR, Wei Q. Sex differences in risk of lung cancer associated with methylene-tetrahydrofolate reductase polymorphisms. Cancer Epidemiol Biomarkers Prev 2005, 14(6):1477-1484. 10.1158/1055-9965.EPI-04-0905, 15941959.