Does erroneous differentiation of tendon-derived stem cells contribute to the pathogenesis of calcifying tendinopathy?

Chinese Medical Journal

Volumn 124, Issue 4, 2011, Pages 606-610

  Rui, Yun Feng ^a,b   Lui, Pauline Po Yee ^a,c   Chan, Lai Shan ^a   Chan, Kai Ming ^a   Fu, Sai Chuen ^a   Li, Gang ^a,c  

^a and Hong Kong Branch of CAS Center for Excellence in Animal Evolution and Genetics   (Hong Kong)

^b SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^c CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Calcifying tendinopathy; Cell differentiation; Mesenchymal stem cells; Pathogenesis; Tendon derived stem cells

Indexed keywords

BONE MORPHOGENETIC PROTEIN 2; BONE MORPHOGENETIC PROTEIN 4; CALCIUM; MESSENGER RNA; OSTEOGENIC PROTEIN 1;

ARTICLE; CALCIFICATION; CALCIFYING TENDINITIS; CARTILAGE CELL; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL RENEWAL; CHONDROGENESIS; EXPERIMENTAL MODEL; HISTOPATHOLOGY; HORSE; HUMAN; NONHUMAN; OSSIFICATION; OSTEOBLAST; PATHOGENESIS; PHENOTYPE; PROTEIN EXPRESSION; SPECIES DIFFERENCE; STEM CELL; TENDINITIS;

EID: 79951777810     PISSN: 03666999     EISSN: None     Source Type: Journal    
DOI: 10.3760/cma.j.issn.0366-6999.2011.04.022     Document Type: Article

References (58)

1. Riley G. Tendinopathy--from basic science to treatment. Nat Clin Pract Rheumatol 2008; 4: 82-89.
2. Xu Y, Murrell GA. The basic science of tendinopathy. Clin Orthop Relat Res 2008; 466: 1528-1538.
3. Uhthoff HK. Calcifying tendinitis, an active cell-mediated calcification. Virchows Arch A Pathol Anat Histol 1975; 366: 51-58.
4. Uhthoff HK, Sarkar K, Maynard JA. Calcifying tendinitis: a new concept of its pathogenesis. Clin Orthop Relat Res 1976; 118: 164-168.
5. Uhthoff HK, Sarkar K. Classification and definition of tendinopathies. Clin Sports Med 1991; 10: 707-720.
6. Uhthoff HK, Loehr JW. Calcific tendinopathy of the rotator cuff: pathogenesis, diagnosis, and management. J Am Acad Orthop Surg 1997; 5: 183-191.
7. Hurt G, Baker CL Jr. Calcific tendinitis of the shoulder. Orthop Clin North Am 2003; 34: 567-575.
8. Kannus P, Jozsa L. Histopathological changes preceding spontaneous rupture of a tendon. A controlled study of 891 patients. J Bone Joint Surg Am 1991; 73: 1507-1525.
9. Maffulli N, Wong J, Almekinders LC. Types and epidemiology of tendinopathy. Clin Sports Med 2003; 22: 675-692.
10. Jim YF, Hsu HC, Chang CY, Wu JJ, Chang T. Coexistence of calcific tendinitis and rotator cuff tear: an arthrographic study. Skeletal Radiol 1993; 22: 183-185.
11. Hashimoto T, Nobuhara K, Hamada T. Pathologic evidence of degeneration as a primary cause of rotator cuff tear. Clin Orthop Relat Res 2003; 415: 111-120.
12. Aina R, Cardinal E, Bureau NJ, Aubin B, Brassard P. Calcific shoulder tendinitis: treatment with modified US-guided fine-needle technique. Radiology 2001; 221: 455-461.
13. Cacchio A, Paoloni M, Barile A, Don R, de Paulis F, Calvisi V, et al. Effectiveness of radial shock-wave therapy for calcific tendinitis of the shoulder: single-blind, randomized clinical study. Phys Ther 2006; 86: 672-682.
14. Rahman MH, Khan SZ, Ramiz MS. Effect of therapeutic ultrasound on calcific supraspinatus tendinitis. Mymensingh Med J 2007; 16: 33-35.
15. Gimblett PA, Saville J, Ebrall P. A conservative management protocol for calcific tendinitis of the shoulder. J Manipulative Physiol Ther 1999; 22: 622-627.
16. Fu SC, Chan BP, Wang W, Pau HM, Chan KM, Rolf CG. Increased expression of matrix metalloproteinase 1 (MMP1) in 11 patients with patellar tendinosis. Acta Orthop Scand 2002; 73: 658-662.
17. Fu SC, Wang W, Pau HM, Wong YP, Chan KM, Rolf CG. Increased expression of transforming growth factor-β1 in patellar tendinosis. Clin Orthop Relat Res 2002; 400: 174-183.
18. Fu SC, Chan KM, Rolf CG. Increased deposition of sulfated glycosaminoglycans in human patellar tendinopathy. Clin J Sport Med 2007; 17: 129-134.
19. Fenwick S, Harrall R, Hackney R, Bord S, Horner A, Hazleman B, et al. Endochondral ossification in Achilles and patella tendinopathy. Rheumatology (Oxford) 2002; 41: 474-476.
20. Archer RS, Bayley JI, Archer CW, Ali SY. Cell and matrix changes associated with pathological calcification of the human rotator cuff tendons. J Anat 1993; 182: 1-11.
21. McClure J. The effect of diphosphonates on heterotopic ossification in regenerating Achilles tendon of the mouse. J Pathol 1983; 139: 419-430.
22. Archambault JM, Jelinsky SA, Lake SP, Hill AA, Glaser DL, Soslowsky LJ. Rat supraspinatus tendon expresses cartilage markers with overuse. J Orthop Res 2007; 25: 617-624.
23. Clegg PD, Strassburg S, Smith RK. Cell phenotypic variation in normal and damaged tendons. Int J Exp Pathol 2007; 88: 227-235.
24. Ferran NA, Maffulli N, Oliva F. Management of recurrent subluxation of the peroneal tendons. Foot Ankle Clin 2006; 11: 465-474.
25. Maffulli N, Reaper J, Ewen SW, Waterston SW, Barrass V. Chondral metaplasia in calcific insertional tendinopathy of the Achilles tendon. Clin J Sport Med 2006; 16: 329-334.
26. Matsumoto I, Ito Y, Tomo H, Nakao Y, Takaoka K. Case reports: ossified mass of the rotator cuff tendon in the subacromial bursa. Clin Orthop Relat Res 2005; 437: 247-250.
27. Rooney P, Walker D, Grant ME, McClure J. Cartilage and bone formation in repairing Achilles tendons within diffusion chambers: evidence for tendon-cartilage and cartilage-bone conversion in vivo. J Pathol 1993; 169: 375-381.
28. Chard MD, Cawston TE, Riley GP, Gresham GA, Hazleman BL. Rotator cuff degeneration and lateral epicondylitis: a comparative histological study. Ann Rheum Dis 1994; 53: 30-34.
29. Corps AN, Robinson AH, Movin T, Costa ML, Hazleman BL, Riley GP. Increased expression of aggrecan and biglycan mRNA in Achilles tendinopathy. Rheumatology (Oxford) 2006; 45: 291-294.
30. Sarkar K, Uhthoff HK. Ultrastructural localization of calcium in calcifying tendinitis. Arch Pathol Lab Med 1978; 102: 266-269.
31. Fu SC, Cheuk YC, Chan KM, Hung LK, Wong MW. Is cultured tendon fibroblast a good model to study tendon healing? J Orthop Res 2008; 26: 374-383.
32. Ameye L, Aria D, Jepsen K, Oldberg A, Xu T, Young MF. Abnormal collagen fibrils in tendons of biglycan/ fibromodulin-deficient mice lead to gait impairment, ectopic ossification, and osteoarthritis. Faseb J 2002; 16: 673-680.
33. Lui PP, Fu SC, Chan LS, Hung LK, Chan KM. Chondrocyte phenotype and ectopic ossification in collagenase-induced tendon degeneration. J Histochem Cytochem 2009; 57: 91-100.
34. Caplan AI, Bruder SP. Mesenchymal stem cells: building blocks for molecular medicine in the 21st century. Trends Mol Med 2001; 7: 259-264.
35. Bosch P, Musgrave DS, Lee JY, Cummins J, Shuler T, Ghivizzani TC, et al. Osteoprogenitor cells within skeletal muscle. J Orthop Res 2000; 18: 933-944.
36. Barbero A, Ploegert S, Heberer M, Martin I. Plasticity of clonal populations of dedifferentiated adult human articular chondrocytes. Arthritis Rheum 2003; 48: 1315-1325.
37. Noth U, Osyczka AM, Tuli R, Hickok NJ, Danielson KG, Tuan RS. Multilineage mesenchymal differentiation potential of human trabecular bone-derived cells. J Orthop Res 2002; 20: 1060-1069.
38. Salingcarnboriboon R, Yoshitake H, Tsuji K, Obinata M, Amagasa T, Nifuji A, et al. Establishment of tendon-derived cell lines exhibiting pluripotent mesenchymal stem cell-like property. Exp Cell Res 2003; 287: 289-300.
39. Bi Y, Ehirchiou D, Kilts TM, Inkson CA, Embree MC, Sonoyama W, et al. Identification of tendon stem/progenitor cells and the role of the extracellular matrix in their niche. Nat Med 2007; 13: 1219-1227.
40. de Mos M, Koevoet WJ, Jahr H, Verstegen MM, Heijboer MP, Kops N, et al. Intrinsic differentiation potential of adolescent human tendon tissue: an in vitro cell differentiation study. BMC Musculoskelet Disord 2007; 8: 16.
41. Rui YF, Lui PP, Li G, Fu SC, Lee YW, Chan KM. Isolation and characterization of multipotent rat tendon-derived stem cells. Tissue Eng Part A 2010; 16: 1549-1558.
42. Rui YF, Lui PP, Ni M, Chan LS, Lee YW, Chan KM. Mechanical loading increased BMP-2 expression which promoted osteogenic differentiation of tendon-derived stem cells. J Orthop Res 2010; Epub ahead of print.
43. Speer MY, Yang HY, Brabb T, Leaf E, Look A, Lin WL, et al. Smooth muscle cells give rise to osteochondrogenic precursors and chondrocytes in calcifying arteries. Circulation Res 2009; 104: 733-741.
44. Kim SY, Choi HY, Myung KB, Choi YW. The expression of molecular mediators in the idiopathic cutaneous calcification and ossification. J Cutan Pathol 2008; 35: 826-831.
45. Lounev VY, Ramachandran R, Wosczyna MN, Yamamoto M, Maidment AD, Shore EM, et al. Identification of progenitor cells that contribute to heterotopic skeletogenesis. J Bone Joint Surg Am 2009; 91: 652-663.
46. Leadbetter WB. Cell-matrix response in tendon injury. Clin Sports Med 1992; 11: 533-578.
47. Almekinders LC, Banes AJ, Ballenger CA. Effects of repetitive motion on human fibroblasts. Med Sci Sports Exerc 1993; 25: 603-607.
48. Yamamoto Y, Furukawa K, Ueyama K, Nakanishi T, Takigawa M, Harata S. Possible roles of CTGF/Hcs24 in the initiation and development of ossification of the posterior longitudinal ligament. Spine 2002; 27: 1852-1857.
49. Forslund C, Aspenberg P. CDMP-2 induces bone or tendon-like tissue depending on mechanical stimulation. J Orthop Res 2002; 20: 1170-1174.
50. Lui PPY, Chan LS, Cheuk YC, Lee YW, Chan KM. Expression of bone morphogenetic protein-2 in the chondrogenic and ossifying sites of calcific tendinopathy and traumatic tendon injury rat models. J Orthop Surg Res 2009; 21: 4-27.
51. Yee Lui PP, Wong YM, Rui YF, Lee YW, Chan LS, Chan KM. Expression of chondro-osteogenic BMPs in ossified failed tendon healing model of tendinopathy. J Orthop Res 2010; Epub ahead of print.
52. Neuwirth J, Fuhrmann RAE, Veit A, Aurich M, Stonans I, Trommer T, et al. Expression of bioactive bone morphogenetic proteins in the subacromial bursa of patients with chronic degeneration of the rotator cuff. Arthritis Res Ther 2006; 8: R92.
53. Hashimoto Y, Yoshida G, Toyoda H, Takaoka K. Generation of tendon-to-bone interface "enthesis" with use of recombinant BMP-2 in a rabbit model. J Orthop Res 2007; 25: 1415-1424.
54. Fu SC, Wong YP, Cheuk YC, Lee KM, Chan KM. TGF-β1 reverses the effects of matrix anchorage on the gene expression of decorin and procollagen type I in tendon fibroblasts. Clin Orthop Relat Res 2005; 431: 226-232.
55. Corps AN, Robinson AHN, Movin T, Costa ML, Hazleman BL, Riley GP. Increased expression of aggrecan and biglycan mRNA in Achilles tendinopathy. Rheumatology (Oxford) 2006; 45: 291-294.
56. Lui PPY, Chan LS, Lee YW, Fu SC, Chan KM. Sustained expression of proteoglycans and collagen type III / Type I ratio in a calcified tendinopathy model. Rheumatology (Oxford) 2010; 49: 231-239.
57. Murata H, Tanaka H, Taguchi T, Shiigi E, Mizokami H, Sugiyama T, et al. Dexamethasone induces human spinal ligament derived cells toward osteogenic differentiation. J Cell Biochem 2004; 92: 715-722.
58. de Mos M, Koevoet W, ven Schie HTM, Lops N, Jahr H, Verhaar JAN, et al. In vitro model to study chondrogenic differentiation in tendinopathy. Am J Sports Med 2009; 37: 1214-1222.