메뉴 건너뛰기




Volumn 116, Issue 1, 2011, Pages 26-33

Two conformational forms of target-bound iC3b that distinctively bind complement receptors 1 and 2 and two specific monoclonal antibodies

Author keywords

Complement C3; complement receptors; immunoglobulin G (IgG); monoclonal antibodies; neo epitopes

Indexed keywords

COMPLEMENT COMPONENT C3; COMPLEMENT COMPONENT C3B; COMPLEMENT COMPONENT C3B RECEPTOR; COMPLEMENT COMPONENT C3D RECEPTOR; IMMUNOGLOBULIN G; MONOCLONAL ANTIBODY;

EID: 79951775926     PISSN: 03009734     EISSN: None     Source Type: Journal    
DOI: 10.3109/03009734.2010.528465     Document Type: Article
Times cited : (10)

References (21)
  • 2
    • 33750859976 scopus 로고    scopus 로고
    • Structure of C3b reveals conformational changes that underlie complement activity
    • DOI 10.1038/nature05172, PII NATURE05172
    • Janssen BJ, Christodoulidou A, McCarthy A, Lambris JD, Gros P. Structure of C3b reveals conformational changes that underlie complement activity. Nature. 2006;444:213-6. (Pubitemid 44722062)
    • (2006) Nature , vol.444 , Issue.7116 , pp. 213-216
    • Janssen, B.J.C.1    Christodoulidou, A.2    McCarthy, A.3    Lambris, J.D.4    Gros, P.5
  • 3
    • 84934436430 scopus 로고    scopus 로고
    • Conformational complexity of complement component C3
    • Janssen BJ, Gros P. Conformational complexity of complement component C3. Adv Exp Med Biol. 2006;586:291-312.
    • (2006) Adv Exp Med Biol , vol.586 , pp. 291-312
    • Janssen, B.J.1    Gros, P.2
  • 4
    • 33751034985 scopus 로고    scopus 로고
    • Structural insights into the central complement component C3
    • DOI 10.1016/j.molimm.2006.06.017, PII S0161589006002203
    • Janssen BJ, Gros P. Structural insights into the central complement component C3. Mol Immunol. 2007;44:3-10. (Pubitemid 44754839)
    • (2007) Molecular Immunology , vol.44 , Issue.1-3 , pp. 3-10
    • Janssen, B.J.C.1    Gros, P.2
  • 6
    • 0023217090 scopus 로고
    • Production of mouse monoclonal antibodies that detect distinct neoantigenic epitopes on bound C3b and iC3b but not on the corresponding soluble fragments
    • DOI 10.1016/0161-5890(87)90023-X
    • Nilsson B, Svensson KE, Borwell P, Nilsson UR. Production of mouse monoclonal antibodies that detect distinct neoantigenic epitopes on bound C3b and iC3b but not on the corresponding soluble fragments. Mol Immunol. 1987;24: 487-94. (Pubitemid 17062638)
    • (1987) Molecular Immunology , vol.24 , Issue.5 , pp. 487-494
    • Nilsson, B.1    Svensson, K.-E.2    Borwell, P.3    Nilsson, U.R.4
  • 7
    • 0026572304 scopus 로고
    • Conformational differences between surface-bound and fluid-phase complementcomponent- C3 fragments: Epitope mapping by cDNA expression
    • Nilsson B, Grossberger D, Ekdahl KN, Riegert P, Becherer D, Nilsson UR, et al. Conformational differences between surface-bound and fluid-phase complementcomponent- C3 fragments: Epitope mapping by cDNA expression. Biochem J. 1992;282:715-21.
    • (1992) Biochem J , vol.282 , pp. 715-721
    • Nilsson, B.1    Grossberger, D.2    Ekdahl, K.N.3    Riegert, P.4    Becherer, D.5    Nilsson, U.R.6
  • 8
    • 0025348989 scopus 로고
    • Neoantigens in complement component C3 as detected by monoclonal antibodies. Mapping of the recognized epitopes by synthetic peptides
    • Nilsson B, Ekdahl KN, Avila D, Nilsson UR, Lambris JD. Neoantigens in complement component C3 as detected by monoclonal antibodies. Mapping of the recognized epitopes by synthetic peptides. Biochem J. 1990;268:55-61. (Pubitemid 20166649)
    • (1990) Biochemical Journal , vol.268 , Issue.1 , pp. 55-61
    • Nilsson, B.1    Nilsson Ekdahl, K.2    Avila, D.3    Nilsson, U.R.4    Lambris, J.D.5
  • 9
    • 0025370167 scopus 로고
    • Inhibition of factor I by diisopropylfluorophosphate. Evidence of conformational changes in factor I induced by C3b and additional studies on the specificity of factor I
    • Ekdahl KN, Nilsson UR, Nilsson B. Inhibition of factor I by diisopropylfluorophosphate. Evidence of conformational changes in factor I induced by C3b and additional studies of the specificity of factor I. J Immunol. 1990;144:4269-74. (Pubitemid 20187768)
    • (1990) Journal of Immunology , vol.144 , Issue.11 , pp. 4269-4274
    • Ekdahl, K.N.1    Nilsson, U.R.2    Nilsson, B.3
  • 10
    • 0000380031 scopus 로고
    • Cellular receptors for fragments of the third component of complement
    • Fearon D. Cellular receptors for fragments of the third component of complement. Immunol Today. 1984;5:105-10.
    • (1984) Immunol Today , vol.5 , pp. 105-110
    • Fearon, D.1
  • 12
    • 0024382146 scopus 로고
    • Variability of CR2 gene products is due to alternative exon usage and different CR2 alleles
    • Toothaker LE, Henjes AJ, Weis JJ. Variability of CR2 gene products is due to alternative exon usage and different CR2 alleles. J Immunol. 1989;142:3668-75. (Pubitemid 19137505)
    • (1989) Journal of Immunology , vol.142 , Issue.10 , pp. 3668-3675
    • Toothaker, L.E.1    Henjes, A.J.2    Weis, J.J.3
  • 14
    • 0019862044 scopus 로고
    • Large scale isolation of functionally active components of the human complement system
    • Hammer CH, Wirtz GH, Renfer L, Gresham HD, Tack BF. Large scale isolation of functionally active components of the human complement system. J Biol Chem. 1981;256:3995-4006.
    • (1981) J Biol Chem , vol.256 , pp. 3995-4006
    • Ch, H.1    Wirtz, G.H.2    Renfer, L.3    Gresham, H.D.4    Tack, B.F.5
  • 15
    • 0017665846 scopus 로고
    • Purification of C3b inactivator and demonstration of its two polypeptide chain structure
    • Fearon DT. Purification of C3b inactivator and demonstration of its two polypeptide chain structure. J Immunol. 1977; 119:1248-52. (Pubitemid 8200371)
    • (1977) Journal of Immunology , vol.119 , Issue.4 , pp. 1248-1252
    • Fearon, D.T.1
  • 16
    • 0000332710 scopus 로고
    • Isolation of beta IF-globulin from human serum and its characterization as the fifth component of complement
    • Nilsson U, Müller-Eberhard H. Isolation of beta IF-globulin from human serum and its characterization as the fifth component of complement. J Exp Med. 1965;122:277-98.
    • (1965) J Exp Med , vol.122 , pp. 277-298
    • Nilsson, U.1    Müller-Eberhard, H.2
  • 17
    • 0034874856 scopus 로고    scopus 로고
    • Deposition of C3b/iC3b leads to the concealment of antigens, immunoglobulins and bound C1q in complement-activating immune complexes
    • DOI 10.1016/S0161-5890(01)00039-6, PII S0161589001000396
    • Nilsson UR. Deposition of C3b/iC3b leads to the concealment of antigens, immunoglobulins and bound C1q in complement-activating immune complexes. Mol Immunol. 2001;38:151-60. (Pubitemid 32786773)
    • (2001) Molecular Immunology , vol.38 , Issue.2-3 , pp. 151-160
    • Nilsson, U.R.1
  • 20
    • 0022501942 scopus 로고
    • Nucleotide sequence of cDNA and derived amino acid sequence of rabbit complement component C3 α-chain
    • Kusano M, Choi NH, Tomita M, Yamamoto K, Migita S, Sekiya T, et al. Nucleotide sequence of cDNA and derived amino acid sequence of rabbit complement component C3 alpha-chain. Immunol Invest. 1986;15:365-78. (Pubitemid 16001325)
    • (1986) Immunological Investigations , vol.15 , Issue.4 , pp. 365-378
    • Kusano, M.1    Choi, N.-H.2    Tomita, M.3
  • 21
    • 0024561883 scopus 로고
    • Distinctive expression of neoantigenic C3(D) epitopes on bound C3 following activation and binding to different target surfaces in normal and pathological human sera
    • DOI 10.1016/0161-5890(89)90127-2
    • Nilsson B, Ekdahl KN, Svensson KE, Bjelle A, Nilsson UR. Distinctive expression of neoantigenic C3(D) epitopes on bound C3 following activation and binding to different target surfaces in normal and pathological human sera. Mol Immunol. 1989;26:383-90. (Pubitemid 19093457)
    • (1989) Molecular Immunology , vol.26 , Issue.4 , pp. 383-390
    • Nilsson, B.1    Ekdahl, K.N.2    Svensson, K.-E.3    Bjelle, A.4    Nilsson, U.R.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.