First case of A859T epidermal growth factor receptor mutation responding to erlotinib

Journal of Thoracic Oncology

Volumn 6, Issue 3, 2011, Pages 639-640

  Le Maignan, Laureline ^a   Mirebeau Prunier, Delphine ^a   Vervueren, Laurent ^a   Jeanfaivre, Thierry ^a   Urban, Thierry ^a   Hureaux, José ^a  

^a ANGERS UNIVERSITY HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOPLATIN; EPIDERMAL GROWTH FACTOR RECEPTOR; ERLOTINIB; GEFITINIB; PEMETREXED;

ADENOCARCINOMA; ADRENAL METASTASIS; ADULT; ARTICLE; CASE REPORT; COMPUTER ASSISTED TOMOGRAPHY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; LUNG BIOPSY; LUNG NODULE; LUNG NON SMALL CELL CANCER; MALE; MUTATION; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL;

ADENOCARCINOMA; ADRENAL GLAND NEOPLASMS; CARCINOMA, NON-SMALL-CELL LUNG; DNA, NEOPLASM; EXONS; HUMANS; LUNG NEOPLASMS; MIDDLE AGED; MUTATION; POLYMERASE CHAIN REACTION; POSITRON-EMISSION TOMOGRAPHY; PROTEIN KINASE INHIBITORS; QUINAZOLINES; RECEPTOR, EPIDERMAL GROWTH FACTOR; TOMOGRAPHY, X-RAY COMPUTED; TREATMENT OUTCOME;

EID: 79951755469     PISSN: 15560864     EISSN: 15561380     Source Type: Journal    
DOI: 10.1097/JTO.0b013e3182037c0c     Document Type: Article

References (6)

1. Rosell R, Moran T, Queralt C, et al. Screening for epidermal growth factor receptor mutations in lung cancer. N Engl J Med 2009;361:958-967.
2. Mok TS, Wu YL, Thongprasert S, et al. Gefitinib or carboplatinpaclitaxel in pulmonary adenocarcinoma. N Engl J Med 2009;361:947-957.
3. Avizienyte E, Ward RA, Garner AP. Comparison of the EGFR resistance mutation profiles generated by EGFR-targeted tyrosine kinase inhibitors and the impact of drug combinations. Biochem J 2008;415: 197-206.
4. Han SW, Kim TY, Hwang PG, et al. Predictive and prognostic impact of epidermal growth factor receptor mutation in non-small-cell lung cancer patients treated with gefitinib. J Clin Oncol 2005;23:2493-2501.
5. Cappuzzo F, Bemis L, Varella-Garcia M. HER2 mutation and response to trastuzumab therapy in non-small-cell lung cancer. N Engl J Med 2006;354:2619-2621. (Pubitemid 43882374)
6. de Gunst MM, Gallegos-Ruiz MI, Giaccone G, et al. Functional analysis of cancer-associated EGFR mutants using a cellular assay with YFPtagged EGFR intracellular domain. Mol Cancer 2007;6:56.