-
1
-
-
34147200289
-
Predictive factors that affect the mobilization of CD34+ cells in healthy donors treated with recombinant granulocyte colony-stimulating factor (G-CSF)
-
DOI 10.1002/jca.20082
-
Martino M, Callea I, Condemi A, Dattola A, Irrera G, Marcuccio D, Messina G, Pontari A, Pucci G, Console G, Lacopino P,. Predictive factors that affect the mobilization of CD34+ cells in healthy donors treated with recombinant granulocyte colony-stimulating factor (G-CSF). J Clin Apheresis 2006; 21: 169-175. (Pubitemid 46579291)
-
(2006)
Journal of Clinical Apheresis
, vol.21
, Issue.3
, pp. 169-175
-
-
Martino, M.1
Callea, I.2
Condemi, A.3
Dettola, A.4
Irrera, G.5
Marcuccio, D.6
Messina, G.7
Pontari, A.8
Pucci, G.9
Console, G.10
Iacopino, P.11
-
2
-
-
0033060685
-
Allogeneic blood progenitor cell collection in normal donors after mobilization with filgrastim: The M.D. Anderson Cancer Center experience
-
DOI 10.1046/j.1537-2995.1999.39060555.x
-
Anderlini P, Donato M, Chan KW, Huh YO, Gee AP, Lauppe MJ, Champlin RE, Körbling M,. Allogeneic blood progenitor cell collection in normal donors after mobilization with filgrastim: the M.D. Anderson Cancer Center experience. Transfusion 1999; 39: 555-560. (Pubitemid 29275323)
-
(1999)
Transfusion
, vol.39
, Issue.6
, pp. 555-560
-
-
Anderlini, P.1
Donato, M.2
Chan, K.-W.3
Huh, Y.O.4
Gee, A.P.5
Lauppe, M.J.6
Champlin, R.E.7
Korbling, M.8
-
3
-
-
19044391218
-
Analysis of factors associated with low peripheral blood progenitor cell collection in normal donors
-
De la Rubia J, Arbona C, de Arriba F, del Cañizo C, Brunet S, Zamora C, Díaz MA, Bargay J, Petit J, de la Serna J, Insunza A, Arrieta R, Pascual MJ, Serrano D, Sanjuan I, Espigado I, Alegre A, Martínez D, Verdeguer A, Martínez C, Benlloch L, Sanz MA,. Analysis of factors associated with low peripheral blood progenitor cell collection in normal donors. Transfusion 2002; 42: 4-9.
-
(2002)
Transfusion
, vol.42
, pp. 4-9
-
-
De La Rubia, J.1
Arbona, C.2
De Arriba, F.3
Del Cañizo, C.4
Brunet, S.5
Zamora, C.6
Díaz, M.A.7
Bargay, J.8
Petit, J.9
De La Serna, J.10
Insunza, A.11
Arrieta, R.12
Pascual, M.J.13
Serrano, D.14
Sanjuan, I.15
Espigado, I.16
Alegre, A.17
Martínez, D.18
Verdeguer, A.19
Martínez, C.20
Benlloch, L.21
Sanz, M.A.22
more..
-
4
-
-
0031855307
-
Mobilization and collection of allogeneic peripheral blood progenitor cells for transplantation
-
Wiesneth M, Schreiner T, Friedrich W, Bunjes D, Duncker C, Krug E, Maccari B, Müller S, Nowak S, Kubanek B,. Mobilization and collection of allogeneic peripheral blood progenitor cells for transplantation. Bone Marrow Transplant 1998; 21 (Suppl. 3): S21-S24. (Pubitemid 28359157)
-
(1998)
Bone Marrow Transplantation
, vol.21
, Issue.SUPPL. 3
-
-
Wiesneth, M.1
Schreiner, T.2
Friedrich, W.3
Bunjes, D.4
Duncker, C.5
Krug, E.6
Maccari, B.7
Muller, S.8
Nowak, S.9
Kubanek, B.10
-
5
-
-
33746513100
-
Peripheral blood stem cell yield in 400 normal donors mobilised with granulocyte colony-stimulating factor (G-CSF): Impact of age, sex, donor weight and type of G-CSF used
-
DOI 10.1111/j.1365-2141.2006.06223.x
-
Ings SJ, Balsa C, Leverett D, Mackinnon S, Linch DC, Watts MJ,. Peripheral blood stem cell yield in 400 normal donors mobilised with granulocyte colony-stimulating factor (G-CSF): impact of age, sex, donor weight and type of G-CSF used. Br J Haematol 2006; 34: 517-525. (Pubitemid 44141718)
-
(2006)
British Journal of Haematology
, vol.134
, Issue.5
, pp. 517-525
-
-
Ings, S.J.1
Balsa, C.2
Leverett, D.3
Mackinnon, S.4
Linch, D.C.5
Watts, M.J.6
-
6
-
-
0029827284
-
Stem cell mobilization in normal donors for allogeneic transplantation: Analysis of safety and factors affecting efficacy
-
Miflin G, Charley C, Stainer C, Anderson S, Hunter A, Russel N,. Stem cell mobilization in normal donors for allogeneic transplantation: analysis of safety and factors affecting efficacy. Br J Haematol 1996; 95: 345-348. (Pubitemid 26360223)
-
(1996)
British Journal of Haematology
, vol.95
, Issue.2
, pp. 345-348
-
-
Miflin, G.1
Charley, C.2
Stainer, C.3
Anderson, S.4
Hunter, A.5
Russell, N.6
-
7
-
-
0031007627
-
Collection of peripheral blood stem cells from normal donors 60 years of age or older
-
Anderlini P, Przepiorka D, Lauppe J, Seong D, Giralt S, Champlin R, Körbling M,. Collection of peripheral blood stem cells from normal donors 60 years of age or older. Br J Haematol 1997; 97: 485-487. (Pubitemid 27224636)
-
(1997)
British Journal of Haematology
, vol.97
, Issue.2
, pp. 485-487
-
-
Anderlini, P.1
Przepiorka, D.2
Lauppe, J.3
Seong, D.4
Giralt, S.5
Champlin, R.6
Korbling, M.7
-
8
-
-
0023092594
-
A new method of classifying prognostic comorbidity in longitudinal studies: Development and validation
-
DOI 10.1016/0021-9681(87)90171-8
-
Charlson ME, Pompei P, Ales KL, MacKenzie CR,. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis 1987; 40: 373-383. (Pubitemid 17055592)
-
(1987)
Journal of Chronic Diseases
, vol.40
, Issue.5
, pp. 373-383
-
-
Charlson, M.E.1
Pompei, P.2
Ales, K.A.3
MacKenzie, C.R.4
-
9
-
-
0029760436
-
The ISHAGE guidelines for CD34+ determination by flow cytometry
-
Sutherland DR, Anderson L, Keeney M, Nayar R, Chin-Yee I,. The ISHAGE guidelines for CD34+ determination by flow cytometry. International Society of Hematotherapy and Graft Engineering J Hematother 1996; 5: 213-226.
-
(1996)
International Society of Hematotherapy and Graft Engineering J Hematother
, vol.5
, pp. 213-226
-
-
Sutherland, D.R.1
Anderson, L.2
Keeney, M.3
Nayar, R.4
Chin-Yee, I.5
-
10
-
-
33748879386
-
Reduced intensity conditioning (RIC) haematopoietic cell transplants in elderly patients with AML
-
DOI 10.1016/j.beha.2006.06.007, PII S1521692606000466, Immune Therapy in Haematological Malignancies
-
Niederwieser D, Lange T, Cross M, Basara N, Al-Ali H,. Reduced intensity conditioning (RIC) haematopoietic cell transplants in elderly patients with AML. Best Pract Res Clin Haematol 2006; 19: 825-838. (Pubitemid 44418026)
-
(2006)
Best Practice and Research: Clinical Haematology
, vol.19
, Issue.4
, pp. 825-838
-
-
Niederwieser, D.1
Lange, T.2
Cross, M.3
Basara, N.4
Al-Ali, H.5
-
11
-
-
33846577834
-
Hematopoietic cell transplantation after reduced-intensity conditioning for older adults with acute myeloid leukemia in complete remission
-
DOI 10.1097/MOH.0b013e3280168462, PII 0006275220070300000010
-
Baron F, Storb R,. Hematopoietic cell transplantation after reduced-intensity conditioning for older adults with acute myeloid leukemia in complete remission. Curr Opin Hematol 2007; 14: 145-151. (Pubitemid 46175099)
-
(2007)
Current Opinion in Hematology
, vol.14
, Issue.2
, pp. 145-151
-
-
Baron, F.1
Storb, R.2
-
12
-
-
54449093967
-
Five-year follow-up of patients with advanced chronic lymphocytic leukemia treated with allogeneic hematopoietic cell transplantation after nonmyeloablative conditioning
-
Sorror ML, Storer BE, Sandmaier BM, Maris M, Shizuru J, Maziarz R, Agura E, Chauncey TR, Pulsipher MA, McSweeney PA, Wade JC, Bruno B, Langston A, Radich J, Niederwieser D, Blume KG, Storb R, Maloney DG,. Five-year follow-up of patients with advanced chronic lymphocytic leukemia treated with allogeneic hematopoietic cell transplantation after nonmyeloablative conditioning. J Clin Oncol 2008; 26: 4912-4920.
-
(2008)
J Clin Oncol
, vol.26
, pp. 4912-4920
-
-
Sorror, M.L.1
Storer, B.E.2
Sandmaier, B.M.3
Maris, M.4
Shizuru, J.5
Maziarz, R.6
Agura, E.7
Chauncey, T.R.8
Pulsipher, M.A.9
McSweeney, P.A.10
Wade, J.C.11
Bruno, B.12
Langston, A.13
Radich, J.14
Niederwieser, D.15
Blume, K.G.16
Storb, R.17
Maloney, D.G.18
-
13
-
-
27844555304
-
Factors associated with granulocyte colony-stimulating factor-induced peripheral blood stem cell yield in healthy donors
-
DOI 10.1111/j.1423-0410.2005.00701.x
-
Suzuya H, Watanabe T, Nakagawa R, Watanabe H, Okamoto Y, Onishi T, Abe T, Kawano Y, Kagami S, Takaue Y,. Factors associated with granulocyte colony-stimulating factor-induced peripheral blood stem cell yield in healthy donors. Vox Sang 2005; 89: 229-235. (Pubitemid 41641103)
-
(2005)
Vox Sanguinis
, vol.89
, Issue.4
, pp. 229-235
-
-
Suzuya, H.1
Watanabe, T.2
Nakagawa, R.3
Watanabe, H.4
Okamoto, Y.5
Onishi, T.6
Abe, T.7
Kawano, Y.8
Kagami, S.9
Takaue, Y.10
-
14
-
-
0031821902
-
Comparison between once a day vs twice a day G-CSF for mobilization of peripheral blood progenitor cells (PBPC) in normal donors for allogeneic PBPC transplantation
-
Arbona C, Prosper F, Benet I, Mena F, Solano C, Garcia-Conde J,. Comparison between once a day vs. twice a day G-CSF for mobilization of peripheral blood progenitor cells (PBSC) in normal donors for allogeneic PBSC transplantation. Bone Marrow Transplant 1998; 22: 39-45. (Pubitemid 28330534)
-
(1998)
Bone Marrow Transplantation
, vol.22
, Issue.1
, pp. 39-45
-
-
Arbona, C.1
Prosper, F.2
Benet, I.3
Mena, F.4
Solano, C.5
Garcia-Conde, J.6
-
15
-
-
0030743512
-
Stem cell mobilization in normal donors
-
Tabilio A, Falzetti F, Giannoni C, Aversa F, Martelli MP, Rosetti M, Caputo P, Chionne F, Gambelunghe C, Martelli MF,. Stem cell mobilization in normal donors. J Hematother 1997; 6: 227-234.
-
(1997)
J Hematother
, vol.6
, pp. 227-234
-
-
Tabilio, A.1
Falzetti, F.2
Giannoni, C.3
Aversa, F.4
Martelli, M.P.5
Rosetti, M.6
Caputo, P.7
Chionne, F.8
Gambelunghe, C.9
Martelli, M.F.10
-
16
-
-
70350513277
-
Donor, recipient, and transplant characteristics as risk factors after unrelated donor PBSC transplantation: Beneficial effects of higher CD34+ cell dose
-
Pulsipher MA, Chitphakdithai P, Logan BR, Leitman SF, Anderlini P, Klein JP, Horowitz MM, Miller JP, King RJ, Confer DL,. Donor, recipient, and transplant characteristics as risk factors after unrelated donor PBSC transplantation: beneficial effects of higher CD34+ cell dose. Blood 2009; 114: 2606-2616.
-
(2009)
Blood
, vol.114
, pp. 2606-2616
-
-
Pulsipher, M.A.1
Chitphakdithai, P.2
Logan, B.R.3
Leitman, S.F.4
Anderlini, P.5
Klein, J.P.6
Horowitz, M.M.7
Miller, J.P.8
King, R.J.9
Confer, D.L.10
-
17
-
-
79951764739
-
Apheresis safety and product yield among elderly donors for allogeneic sibling hematopoietic cell transplantation (HCT)
-
(abstract 5223).
-
Ghada A, Guthrie KA, Sorror ML, Linenberger M,. Apheresis safety and product yield among elderly donors for allogeneic sibling hematopoietic cell transplantation (HCT). Blood 2006; 108 (abstract 5223).
-
(2006)
Blood
, pp. 108
-
-
Ghada, A.1
Guthrie, K.A.2
Sorror, M.L.3
Linenberger, M.4
-
18
-
-
62549146622
-
Regeneration, health status and quality of life after rhG-CSF-stimulated stem cell collection in healthy donors: A cross-sectional study
-
Leitner GC, Baumgartner K, Kalhs P, Biener D, Greinix HT, Hoecker P, Worel N,. Regeneration, health status and quality of life after rhG-CSF-stimulated stem cell collection in healthy donors: a cross-sectional study. Bone Marrow Transplant 2009; 43: 357-363.
-
(2009)
Bone Marrow Transplant
, vol.43
, pp. 357-363
-
-
Leitner, G.C.1
Baumgartner, K.2
Kalhs, P.3
Biener, D.4
Greinix, H.T.5
Hoecker, P.6
Worel, N.7
-
19
-
-
65349145905
-
Adverse events among 2408 unrelated donors of peripheral blood stem cells: Results of prospective trial from the National Marrow Donor Program
-
Pulsipher MA, Chiphakdithai P, Miller JP, Logan BR, King RJ, Rizzo JD, Leitman SF, Anderlini P, Haagenson MD, Kurian S, Klein JP, Horowitz MM, Confer DL,. Adverse events among 2408 unrelated donors of peripheral blood stem cells: results of prospective trial from the National Marrow Donor Program. Blood 2009; 113: 3604-3611.
-
(2009)
Blood
, vol.113
, pp. 3604-3611
-
-
Pulsipher, M.A.1
Chiphakdithai, P.2
Miller, J.P.3
Logan, B.R.4
King, R.J.5
Rizzo, J.D.6
Leitman, S.F.7
Anderlini, P.8
Haagenson, M.D.9
Kurian, S.10
Klein, J.P.11
Horowitz, M.M.12
Confer, D.L.13
-
20
-
-
49449118199
-
Recovery and safety profiles of marrow and PBSC donors: Experience of the national marrow donor program
-
Miller JP, Perry EH, Price TH, Bolan CD, Jr., Karanes C, Boyd TM, Chitphakdithai P, King RJ,. Recovery and safety profiles of marrow and PBSC donors: experience of the national marrow donor program. Biol Blood Marrow Transplant 2008; 14: 29-36.
-
(2008)
Biol Blood Marrow Transplant
, vol.14
, pp. 29-36
-
-
Miller, J.P.1
Perry, E.H.2
Price, T.H.3
Bolan, Jr.C.D.4
Karanes, C.5
Boyd, T.M.6
Chitphakdithai, P.7
King, R.J.8
-
21
-
-
0035037982
-
Peripheral blood stem cell donation: An analysis from the International Bone Marrow Transplant Registry (IBMTR) and European Group for Blood and Marrow Transplant (EBMT) databases
-
DOI 10.1038/sj.bmt.1702875
-
Anderlini P, Rizzo JD, Nugent ML, Schmitz N, Champlin RE, Horowitz MM,. Peripheral blood stem cell donation: an analysis from the International Bone Marrow Transplant Registry (IBMTR) and European Group for Blood and Marrow Transplant (EBMT) databases. Bone Marrow Transplant 2001; 27: 689-692. (Pubitemid 32409442)
-
(2001)
Bone Marrow Transplantation
, vol.27
, Issue.7
, pp. 689-692
-
-
Anderlini, P.1
Rizzo, J.D.2
Nugent, M.L.3
Schmitz, N.4
Champlin, R.E.5
Horowitz, M.M.6
-
22
-
-
58149260470
-
Severe events in donors after allogeneic hematopoietic stem cell donation
-
Halter J, Kodera Y, Urbano Ispizua A, Greinix HT, Schmitz N, Favre G, Baldomero H, Niederwieser D, Apperley JF, Gratwohl A,. Severe events in donors after allogeneic hematopoietic stem cell donation. Haematologica 2009; 94: 94-101.
-
(2009)
Haematologica
, vol.94
, pp. 94-101
-
-
Halter, J.1
Kodera, Y.2
Urbano Ispizua, A.3
Greinix, H.T.4
Schmitz, N.5
Favre, G.6
Baldomero, H.7
Niederwieser, D.8
Apperley, J.F.9
Gratwohl, A.10
-
23
-
-
0036327614
-
Induction of a hypercoagulability state and endothelial cell activation by granulocyte colony-stimulating factor in peripheral blood stem cell donors
-
DOI 10.1089/15258160260194820
-
Canales MA, Arrieta R, Gomez-Rioja R, Diez J, Jimenez-Yuste V, Hernandez-Navarro F,. Induction of a hypercoagulability state and endothelial cell activation by granulocyte colony-stimulating factor in peripheral blood stem cell donors. J Hematother Stem Cell Res 2002; 11: 675-681. (Pubitemid 34851799)
-
(2002)
Journal of Hematotherapy and Stem Cell Research
, vol.11
, Issue.4
, pp. 675-681
-
-
Canales, M.A.1
Arrieta, R.2
Gomez-Rioja, R.3
Diez, J.4
Jimenez-Yuste, V.5
Hernandez-Navarro, F.6
-
24
-
-
77953052796
-
Selection of adult unrelated hematopoietic stem cell donors: Beyond the HLA
-
Confer DL, Agrese LK, Navarro W, Madrigal A,. Selection of adult unrelated hematopoietic stem cell donors: beyond the HLA. Biol Blood Marrow Transplant 2010; 16 (1 Suppl): S8-S11.
-
(2010)
Biol Blood Marrow Transplant
, vol.16
, Issue.1 SUPPL.
-
-
Confer, D.L.1
Agrese, L.K.2
Navarro, W.3
Madrigal, A.4
-
25
-
-
0035496909
-
Donor characteristics as risk factors in recipients after transplantation of bone marrow from unrelated donors: The effect of donor age
-
Kollman C, Howe CWS, Anasetti C, Antin JH, Davies SM, Filipovich AH, Hegland J, Kamani N, Kernan NA, King R, Ratanatharathorn V, Weisdorf D, Confer DL,. Donor characteristics as risk factors in recipients after transplantation of bone marrow from unrelated donors: the effect of donor age. Blood 2001; 98: 2043-2051.
-
(2001)
Blood
, vol.98
, pp. 2043-2051
-
-
Kollman, C.1
Howe, C.W.S.2
Anasetti, C.3
Antin, J.H.4
Davies, S.M.5
Filipovich, A.H.6
Hegland, J.7
Kamani, N.8
Kernan, N.A.9
King, R.10
Ratanatharathorn, V.11
Weisdorf, D.12
Confer, D.L.13
-
26
-
-
55949099856
-
Matched unrelated or matched sibling donors result in comparable survival after allogeneic stem-cell transplantation in elderly patients with acute myeloid leukemia: A report from the cooperative German Transplant Study Group
-
Schetelig J, Bornhäuser M, Schmid C, Hertenstein B, Schwerdtfeger R, Martin H, Stelljes M, Hegenbart U, Schäfer-Eckart K, Füssel M, Wiedemann B, Thiede C, Kienast J, Baurmann H, Ganser A, Kolb HJ, Ehninger G,. Matched unrelated or matched sibling donors result in comparable survival after allogeneic stem-cell transplantation in elderly patients with acute myeloid leukemia: a report from the cooperative German Transplant Study Group. J Clin Oncol 2008; 26: 5183-5191.
-
(2008)
J Clin Oncol
, vol.26
, pp. 5183-5191
-
-
Schetelig, J.1
Bornhäuser, M.2
Schmid, C.3
Hertenstein, B.4
Schwerdtfeger, R.5
Martin, H.6
Stelljes, M.7
Hegenbart, U.8
Schäfer-Eckart, K.9
Füssel, M.10
Wiedemann, B.11
Thiede, C.12
Kienast, J.13
Baurmann, H.14
Ganser, A.15
Kolb, H.J.16
Ehninger, G.17
-
27
-
-
34247163959
-
Allogeneic marrow stem-cell transplantation from human leukocyte antigen-identical siblings versus human leukocyte antigen-allelic-matched unrelated donors (10/10) in patients with standard-risk hematologic malignancy: A prospective study from the French society of bone marrow transplantation and cell therapy
-
DOI 10.1200/JCO.2006.08.0952
-
Yakoub-Agha I, Mesnil F, Kuentz M, Boiron JM, Ifrah N, Milpied N, Chehata S, Esperou H, Vernant JP, Michallet M, Buzyn A, Gratecos N, Cahn JY, Bourhis JH, Chir Z, Raffoux C, Socié G, Golmard JL, Jouet JP,. Allogeneic marrow stem-cell transplantation from human leukocyte antigen-identical siblings versus leukocyte antigen-allelic-matched unrelated donors (10/10) in patients with standard-risk hematologic malignancy: a prospective study from the French Society of Bone Marrow Transplantation and Cell Therapy. J Clin Oncol 2006; 24: 5695-5702. (Pubitemid 46631311)
-
(2006)
Journal of Clinical Oncology
, vol.24
, Issue.36
, pp. 5695-5702
-
-
Yakoub-Agha, I.1
Mesnil, F.2
Kuentz, M.3
Boiron, J.M.4
Ifrah, N.5
Milpied, N.6
Chehata, S.7
Esperou, H.8
Vernant, J.-P.9
Michallet, M.10
Buzyn, A.11
Gratecos, N.12
Cahn, J.Y.13
Bourhis, J.H.14
Chir, Z.15
Raffoux, C.16
Socie, G.17
Golmard, J.L.18
Jouet, J.-P.19
-
28
-
-
33745742607
-
Does younger donor age affect the outcome of reduced-intensity allogeneic hematopoietic stem cell transplantation for hematologic malignancies beneficially?
-
Mehta J, Gordon LI, Tallman MS, Winter JN, Evens AM, Frankfurt O, Williams SF, Grinblatt D, Kaminer L, Meagher R, Singhal S,. Does younger donor age affect the outcome of reduced-intensity allogeneic hematopoietic stem cell transplantation for hematologic malignancies beneficially? Bone Marrow Transplant 2006; 38: 95-100.
-
(2006)
Bone Marrow Transplant
, vol.38
, pp. 95-100
-
-
Mehta, J.1
Gordon, L.I.2
Tallman, M.S.3
Winter, J.N.4
Evens, A.M.5
Frankfurt, O.6
Williams, S.F.7
Grinblatt, D.8
Kaminer, L.9
Meagher, R.10
Singhal, S.11
-
29
-
-
37349118061
-
High-resolution donor-recipient HLA matching contributes to the success of unrelated donor marrow transplantation
-
DOI 10.1182/blood-2007-06-097386
-
Lee SJ, Klein J, Haagenson M, Baxter-Lowe LA, Confer DL, Eapen M, Fernandez-Vina M, Flomenberg N, Horowitz M, Hurley CK, Noreen H, Oudshoorn M, Petersdorf E, Setterholm M, Spellman S, Weisdorf D, Williams TM, Anasetti C,. High-resolution donor-recipient HLA matching contributes to the success of unrelated donor marrow transplantation. Blood 2007; 110: 4576-4583. (Pubitemid 351377826)
-
(2007)
Blood
, vol.110
, Issue.13
, pp. 4576-4583
-
-
Lee, S.J.1
Klein, J.2
Haagenson, M.3
Baxter-Lowe, L.A.4
Confer, D.L.5
Eapen, M.6
Fernandez-Vina, M.7
Flomenberg, N.8
Horowitz, M.9
Hurley, C.K.10
Noreen, H.11
Oudshoorn, M.12
Petersdorf, E.13
Setterholm, M.14
Spellman, S.15
Weisdorf, D.16
Williams, T.M.17
Anasetti, C.18
|