Predictive value of routine transcutaneous tissue oxygen tension (tcpo2) measurement for the risk of non-healing and amputation in diabetic foot ulcer patients with non-palpable pedal pulses

Medical Science Monitor

Volumn 16, Issue 6, 2010, Pages

  Ladurner, Ruth ^a   Küper, Markus ^a   Königsrainer, Ingmar ^a   Löb, Stefan ^a   Wichmann, Dörte ^a   Königsrainer, Alfred ^a   Coerper, Stephan ^a   Beckert, Stefan ^a  

^a UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

Author keywords

Diabetic foot ulcer; Microcirculation; Non palpable pedal pulses; Transcutaneous tissue oxygen tension; Wound healing

Indexed keywords

ANTIBIOTIC AGENT; OXYGEN;

ADULT; AGED; ARTICLE; CONTROLLED STUDY; DIABETIC FOOT; FEMALE; FOLLOW UP; FOOT AMPUTATION; HOSPITALIZATION; HUMAN; MAJOR CLINICAL STUDY; MALE; OUTPATIENT DEPARTMENT; PREDICTIVE VALUE; PULSE RATE; SOFT TISSUE INFECTION; TRANSCUTANEOUS OXYGEN MONITORING; ULCER HEALING; WOUND CARE; WOUND HEALING; AMPUTATION; BLOOD; MIDDLE AGED; PATHOPHYSIOLOGY; RISK; TIME FACTOR; TREATMENT OUTCOME; VERY ELDERLY;

ADULT; AGED; AGED, 80 AND OVER; AMPUTATION; DIABETIC FOOT; FEMALE; HUMANS; MALE; MIDDLE AGED; OXYGEN; PREDICTIVE VALUE OF TESTS; RISK; TIME FACTORS; TREATMENT OUTCOME; WOUND HEALING;

EID: 79951750845     PISSN: 12341010     EISSN: 16433750     Source Type: Journal    
DOI: None     Document Type: Article

References (28)

1. Knighton DR, Halliday B, Hunt TK: Oxygen as an antibiotic: the effect inspired oxygen on infection. Arch Surg, 2004; 119: 199-204
2. Hunt TK, Niinikoski J, Zederfeldt B: Role of oxygen in repair processes. Acta Chir Scand, 1972; 138: 109-110
3. Hunt TK, Beckert S: The theoretical and practical aspects of oxygen in wound healing. In: Lee B (ed.), The Wound Management Manual. McGraw Hill, 2004; Chapter 3: 44-54
4. Beckert S, Witte M, Wicke C et al: A new wound-based severity score for diabetic foot ulcers: A prospective analysis of 1,000 patients. Diabetes Care, 2006, 29: 988-992
5. Franzeck UK, Bernstein EF, Talke P et al: Transcutaneous PO2 measurements in health and peripheral occlusive disease. Surgery, 1982; 91: 156-163
6. Rooke TW, Osmundson PJ: Variability and reproducibility of transcutaneous oxygen tension measurements in the assessment of peripheral vascular disease. Angiology, 1989; 40: 695-700
7. Kalani M, Brismar K, Fagrell B et al: Transcutaneous oxygen tension and toe blood pressure as predictors for outcome of diabetic foot ulcers. Diabetes Care, 1999; 22: 147-151
8. Wagner HJ, Schmitz R, Alfke H, Klose KJ: Influence of percutaneous transluminal angioplasty on transcutaneous oxygen pressure in patients with peripheral arterial occlusive arterial disease. Radiology, 2003; 226: 791-797
9. Caselli A, Latini V, Lapenna A et al: Transcutaneous oxygen tension monitoring after successful revascularization in diabetic patients with ischaemic foot ulcers. Diabet Med, 2005, 22: 460-465
10. De Graaf JC, Ubbink DT, Legemate DA et al: Interobserver and intraobserver reproducibility of peripheral blood and oxygen pressure measurements in the assessment of lower extremity arterial disease. J Vasc Surg, 2001; 33: 1033-1040
11. Jörneskog G, Djavani K, Brismar K: Day to day variability of transcutaneous oxygen tension in patients with diabetes mellitus and peripheral occlusive disease. J Vasc Surg, 2001; 34: 277-282
12. Wutschert R, Bounameaux H: Determination of amputation level in ischemic limbs. Reappraisal of the measurement of TcPO2. Diabetes Care, 1997, 20: 1315-1318
13. Ubbink DT, Geert HJJ, Spincemaille GH et al: Prediction of imminent amputation in patients with non-reconstructible leg ischemia by means of microcirculatory investigations. J Vasc Surg, 1999; 30: 114-121
14. Ratliff DA, Clyne CA, Chant AD, Webster JH: Prediction of amputation wound healing: the role of transcutaneous pO2 assessment. Br J Surg, 1984; 71: 219-222
15. Gibbons GW, Wheelock FC, Siembieda C et al: Non invasive prediction of amputation level in diabetic patients. Arch Surg, 1979; 114: 1253-1257
16. Padberg FT, Back TL, Thompson PN, Hobson RW: Transcutaneous oxygen (TcPO2) estimates probability of healing in the ischemic extremity. J Surg Res, 1996; 60: 365-369
17. Coerper S, Wicke C, Pfeffer F et al: Documentation of 7051 Chronic Wounds Using a New Computerized System Within a Network of Wound Care Centers. Arch Surg, 2004; 139: 251-258
18. Coerper S, Schäffer M, Enderle M et al: Die chirurgische Wundsprechstunde. Chirurg, 1999; 70: 480-481
19. Prompers L, Schaper N, Apelqvist J et al: Prediction of outcome in individuals with diabetic foot ulcers: focus on the differences between individuals with and without peripheral arterial disease. The EURODIALE Study. Diabetologia, 2008; 51: 747-755
20. Putz Z, Nadas J, Jermendy G: Severe but preventable foot burn injury in diabetic patients with peripheral neuropathy. Med Sci Monit, 2008; 14(9): CS89-CS91
21. Ertugrul BM, Savk O, Ozturk B et al: The diagnosis of diabetic foot osteomyelitis: examination findings and laboratory values. Med Sci Monit, 2009; 15(6): CR307-CR312
22. Khan NA, Rahim SA, Anand SS et al: Does the clinical examination predict lower extremity peripheral arterial disease? Jama, 2006; 295: 536-546
23. Cournot M, Boccalon H, Cambou JP et al: Accuracy of the screening physical examination to identify infclinical atherosclerosis and peripheral arterial disease in asymptomatic infjects. J Vasc Surg, 2007; 46: 1215-1221
24. Urbancic-Rovan V, Bernjak A, Stefanovska A et al: Macro- and microcirculation in the lower extremities - possible relationship. Diabetes Res Clin Pract, 2006; 73: 166-173
25. Diamantopoulos EJ, Haritos D, Yfandi G et al: Management and outcome of severe diabetic foot infections. Exp Clin Endocrinol, 1998; 106: 346-352
26. Ballard JL, Eke CC, Bunt TJ, Killeen JD: A prospective evaluation of transcutaneous oxygen measurements in the management of diabetic foot problems. J Vasc Surg, 1995; 22: 485-490; discussion 490-92
27. Pecoraro RE, Ahroni JH, Boyko EJ, Stensel VL: Chronology and determinants of tissue repair in diabetic lower-extremity ulcers. Diabetes, 1991; 40: 1305-1313
28. De Graaf JC, Ubbink DT, Legemate DA et al: Evaluation of toe pressure and transcutaneous oxygen measurement in management of chronic critical leg ischemia: A diagnostic randomized clinical trial. J Vasc Surg, 2003; 38: 528-534